Protective Effects of N-acetylcystenine and Selenium against Doxorubicin Toxicity in Rats

Yeo-sung Yoon,Sun-don Kim,Min-hye Lee,Heung-shik S.Lee,In-se Lee,Je-kyung Sung,Eun-sung Park 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2

Effects of N-acetylcysteine and Selenium against Doxorubicin Toxicity in RatsEun-sung Park, Sun-don Kim1, Min-hye Lee, Heung-shik S. Lee, In-se Lee, Je-kyung Sung and Yeo-sung Yoon*

변환된 자기회귀이동평균 모형에서의 예측구간추정

조혜민,오승언,여인권,Cho, Hye-Min,Oh, Sung-Un,Yeo, In-Kwon 한국통계학회 2007 응용통계연구 Vol.20 No.3

시계열자료를 분석하는데 있어 중요한 목적 중에 하나가 미래값에 대한 예측이다. 일반적으로 자기회귀이동평균모형에서는 백색잡음이 정규분포를 따른다는 가정 하에서 모수의 추론과 예측 및 예측구간의 추정이 이루어지고 있다. 그러나 자료가 이러한 가정을 만족하지 않는 경우, 자료를 가정에 맞게 변환시킨 후 분석하는 방법을 생각해 볼 수 있다. 이 논문에서는 변환된 자료를 분석하여 얻은 결과를 이용하여 본래의 척도에서의 미래값에 대한 예측구간을 추정하는 문제에 대해 알아본다. 제안하는 방법에서는 먼저 적절한 변환을 이용하여 자료를 정규가정을 만족하도록 변환시키고 변환된 자료를 이용하여 미래값에 대한 예측구간을 추정한 후, 역변환을 이용하여 예측구간을 추정한다. 이 논문에서는 시계열분석에서 모델링이 상대적으로 어려운 왜도의 문제를 해결하기 위해 Yeo-Johnson 변환을 중심으로 한 방법론을 소개한다. 모의실험 결과 제안된 방법에 의한 단측예측구간의 포함확률이 변환을 사용하지 않은 구간보다 명목수준에 가까운 것을 확인하였다. One of main aspects of time series analysis is to forecast future values of series based on values up to a given time. The prediction interval for future values is usually obtained under the normality assumption. When the assumption is seriously violated, a transformation of data may permit the valid use of the normal theory. We investigate the prediction problem for future values in the original scale when transformations are applied in ARMA models. In this paper, we introduce the methodology based on Yeo-Johnson transformation to solve the problem of skewed data whose modelling is relatively difficult in the analysis of time series. Simulation studies show that the coverage probabilities of proposed intervals are closer to the nominal level than those of usual intervals.

이상화 문학에 나타난 시적 상상력의 근원 연구

유신지 ( Yu Shin-ji ),여상임 ( Yeo Sang-im ) 한국문학언어학회(구 경북어문학회) 2017 어문론총 Vol.74 No.-

이상화문학에 대한 논의는 이상화 당대는 물론, 1960년대부터 지금까지 상당히 구체적으로 진행되었다. 주로 상징주의나 낭만주의와 같은 문예사조적인 경향이나 저항시인이라는 민족주의적인 관점에서 연구가 많이 진행되었다. 그러나 이러한 관점에서는 이상화 문학 전반에서 드러나는 동양적이고 전통적인 사유를 다 해명하는 데는 한계가 있었다. 이상화문학과 그의 사상의 근저에는 동학이나 천도교적인 사상의 근간을 이루는 내재적 초월의 사유가 자리하고 있다. 내재적 초월의 사유는 이상화 문학의 곳곳에서 다양한 모습으로 드러나고 있다. 본고에서는 이상화의 시적 상상력의 근원이 이러한 내재적 초월의 사유로 파악될 수 있다고 보고, 전통시학의 관점, 특히 기층철학을 토대로 이상화의 문학 텍스트를 분석해보고자 했다. 특히 이상화의 전기적 사실들을 살펴보면, 그의 사상과 사유가 형성되는 중요한 시기인 십대와 이십대 전반에 걸쳐서 천도교적인 색채가 짙은 인물들과 깊은 교류를 맺었고 그와 관련된 활동들을 했다는 것을 알 수 있다. 또한 그가 제시하는 문학론이나 시작품들에서도 그러한 사유들이 드러나는 것을 볼 수 있다. 이상화의 문학평론이나 시에서는 우리 고유의 민속 신앙인 샤머니즘과 이를 계승한 동학사상의 색채가 드러난다. 그의 시작품들에서도 특징적인 것이 ‘하늘’,‘신령’, ‘검’, ‘동굴’ 등과 같은 시어들이 빈번히 쓰이고 있는데, 이러한 시어들은 이상화 텍스트 전반에서 관찰되는 ‘내재적 초월’의 사유들을 드러내는 것으로 쓰이고 있는 것을 볼 수 있다. 이러한 양상은 기존의 논의에서 채 규명되지 못한 부분들로, 동양적이고 전통적인 사유의 지평 안에서만 비로소 설명이 되는 부분이기도 하다. 이러한 논의는 이상화가 1920년대 시단의 다양한 흐름 속에서도 그 시류에 휩쓸리지 않고, 우리의 자생적인 사상이라 할 수 있는 전통철학의 토대 위에 그 나름의 시세계를 구축하였음을 확인할 수 있게 해주며, 나아가 이상화 문학을 바라보는 새로운 해석의 지평을 넓혀볼 수 있다는 점에서 의의가 있다. Untill now, the study on Lee Sang-hwa’s literature has been done very widely. Most rearchess have been done in the point of view of symbolism, romanticism, or nationalism. But, through these views, we couldn't find the basic thoughts of his Literature. There are immanent transcendence in the origin of his Literature and his own ideas. Therefor, at this thesis, we found that the origin of poetic imagination in Lee Sang-hwa’s literature is based on the oriental and traditional thoughts. Especially, when we searched Lee Sang-hwa’s biography, we found that he was related to the people who had Chondo-kyo belief. Such thoughts appeared his literary theory or in his prototypes. His literary criticism and poetry reveal the color of Korean folk faith, Shamanism and Donghak's succession. In his poetry text, the words such as 'heaven', 'spirit', 'sword' and 'cave' are frequently used. And these words are used to reveal the aspects of 'Immanent transcendence' observed wholy. This aspect can not be clarified in the existing discourse and is only explained within the horizon of the traditional thoughts. This study enables us to confirm that Lee-Sanghwa has built his own poetry system on the basis of traditional philosophy which is not influenced by the currents in the various ideal flows of the 1920s. In addition, it has a significance in that it can broaden the horizon of the new interpretation in reading the Lee-Sanghwa’s literature.

해상보험에 있어서 전쟁위험에 관한 연구

여성구 慶南大學校 産業經營硏究所 2001 産業經營 Vol.29 No.-

신뢰성 이론에 의한 PSC박스거더교의 시공중 안전성 평가

여성욱,장일영,송재호 금오공과대학교 산업기술개발연구원 2000 産業技術開發硏究 Vol.16 No.-

Recently, the bridge structures are becoming longer and larger mainly due to the development in materials, the improvement in construction and the advance in structural analysis and design technique. So, construction of this type of bridges such as cable stayed bridge, suspension bridge and segmental PSC box girder bridge are increasing nowadays. Especially, the segmental PSC box girder bridges are widely constructed for medium and long span bridges. But it has been well known that structural failure probability during the construction, in general is higher than that during the service life due to lack of the empirical judgement, field data and standard process for the construction as well as due to high uncertainty involved in the evaluation of loads and strength of structures during construction. So in this study for the reliability based safety assessment of segmental PSC box girder bridges during construction, which are erected by Free Cantilever Methods, a set of linear strength limit state models are suggested for the box girder. The reliability of the structures using the proposed practical limit state model is evaluated by using Advanced First Order Second Moment method. Also the proposed models are applied to the safety assessment of a real bridge during construction stage in order to check their applicability in practice for the bridge assessment engineering. Finally, the important factors of construction stages are identified through the sensitivity analysis of the main random variables.

6주간 유산소 운동 트레이닝이 심장 질환자들의 운동수행능력과 혈액 생화학 성분에 미치는 영향

여남회,김상수 東亞大學校附設스포츠科學硏究所 2001 스포츠科學硏究論文集 Vol.19 No.-

Seven male patients with heart diseases, over 50.6 years old, were randomly selected for this study. They received 6 week aerobic exercise with 60% maximum heart rate at 2 or 3 times a week. ECG was measured during exercise, and blood sample was taken before and after exercise. The conclusions of this study are the followings. 1) Mean exercise durations were 1317±2:11 min, 9:58±1:36 min, 10:39±2:21 min at pre phase, middle phase, and post phase, respectively. The mean exercise duration was significantly decreased during training(p<0.001) and after training(p<0.05). 2) LDL-cholesterol was decreased from 116.14±27.63 mg/dl to 104.42±36.78 mg/dl after training(p<0.05). 3) MCV was significantly decreased from 93.14±3.32fl to 89.72±3.16fl after training(p<0.01). In conclusion, 6 week aerobic exercise decreased the diastolic blood pressure, metabolism index, exercise duration and LDL-cholesterol among male patients with heart disease.

금속사출성형에 의한 중합금 소결체 부품 제조에 관한 연구

여환균,김병진,김길수,김성훈,송준호,한관희 嶺南大學校 工業技術硏究所 2003 工業技術硏究所論文集 Vol.31 No.2

In this study we demonstrate that a small complex part of a tungsten-based heavy alloy (W-Ni-Cu) can be readily manufactured by utilizing the metal injection molding (MIM) technology. We use a simple thermoplastic binder system, containing low density polyethylene, paraffin wax, and stearic acid. To remove the organic binder from the molded part, we employ the solvent extraction and thermal debinding processes. Densification of debound parts is achieved by sintering in hydrogen atmosphere. The experimental results of the optimization of process variables to manufacture the heavy alloy part are described, with a brief discussion.

격자이론에 의한 영어강세형

여상필 신영어영문학회 2001 신영어영문학 Vol.19 No.-

The purpose of this article is to show how the apparently varied and unpredictable stress patterns of English can be account for based on a serious of principles and parameters of grid theory. End Stress can account for the contrasting English stress patterns of phrases and verbs/unsuffixed adjectives, on the one hand, and compounds and nouns/suffixed adjectives, on the other. The antepenultimate stress patterns of nouns of more than two syllables can be accounted for by building the bracketed left-headed feet iteratively from right to left. The grid dominating the heavy syllables is projected onto line 1. Verbs and unsuffixed adjectives with final branching rimes can be explained simply by making the final syllable extrametrical. I also discussed the arguments for the bracketed metrical grid theory based on Hayes's.

교외지역에서 토양 중 PBDEs 종별 농도 특성

이성희,여현구 忠州大學校 2010 한국교통대학교 논문집 Vol.45 No.-

Polybrominated diphenyl ethers(PBDEs) was measured in soil samples of Ansung in Kyonggi-province to investigate concentration characteristics of PBDEs. Total concentration of PBDE were 2,205.3 pg/g dry weight (DW) in soil sample. BDE-209 showed as the most abundant congener in soil samples which was related to imported amount and usage amount of deca-BDE technical mixture in Korea. Also, BDE-99, BDE-47, BDE-100 deposition in soil sample was higher than other congeners and was related to the imported and usage amount reported for penta-BDE technical mixture in Korea. Correlation coefficient between PBDE contribution and technical mixture formulation(Bromokal 70-5DE) were significant(r=0.91, p<0.01) which suggests the influence of sources in this technical mixtures.

분심기음의 항암작용 및 면역기능에 관한 연구

여대원,김진성,윤상협,류봉하,류기원 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2003 東西醫學硏究所 論文集 Vol.2003 No.-

This study was performed to investigate the effect of Bunsimgieum on antitumor effect after sarcoma-180 cells transplantation into peritoneal cavity or left groin and immune responses on the depressed immunity induced by methotrexate in mice. The Bunsimgieum extract of 10㎎/㎏ was orally administered 14 days for antitumor effects and 21 days for immune responses. 50% inhibitory concentration(IC_(50)) of SUN-1, SUN-C4. and SUN-396 cancer cell, mean sunvival days and body weight of tumor bearing mice, and growth of tumor mass for antitumor effect; delayed type hypersentivity, hemagglutinin titer, hemolysis titer, rosette forming cells, natured killer cell activity, lymphocyte transformation. productivity of interleukin-2 and phagocytic activity for their immune responses were measured in ICR mice. Significance in antitumor effect is noted in the enlongation of mean life days and inhibition of tumor growth(p<0.01 respectively). Significance of immune responses is also noted in hemolysis titer, lymphocyte transfumotion IL-2 productivity, phagocytic activity, and natural killer cell activity at E/T ratio 100 : 1(p<0.01, respectively). Significant in rosette cell formation was seen dosage of 20㎎/㎏(p<0.01) However, Difference of body weight as antitumor effect, delayed type hypersensitivity, and hemagglutinin titer were not shown significantly. According to the above results, it could be suggested that Bunsimgieum has prominent antitumor and immunity enhancing effect.