Optimal Dietary Ratio of Spray Dried Plasma Protein (SDPP) and Dried Porcine Solubles (DPS) in Improving Growth Performance and Immune Status in Pigs Weaned at 21 Days of Age

Kim, J.D.,Hyun, Y.,Sohn, K.S.,Kim, T.J.,Woo, H.J.,Han, In K. Asian Australasian Association of Animal Productio 2001 Animal Bioscience Vol.14 No.3

An experiment was conducted to determine the optimal inclusion ratio of spray dried plasma protein (SDPP) and dried porcine solubles (DPS) for maximizing growth and improving immunity in weaned pigs. One hundred-fifty male (barrow) pigs were allotted in a completely randomized block design. Treatments were as follows: 1) control (6% SDPP), 2) S6D6 (6% SDPP+6% DPS), 3) S6D3 (6% SDPP+3% DPS), 4) S3D6 (3% SDPP+6% DPS) and 5) S3D3 (3% SDPP+3% DPS). Each treatment has 6 replicates with 5 pigs per replicate. Average daily gain (ADG) and average daily feed intake (ADFI) were highest, but not significantly different when pigs were fed a diet contained 6% SDPP and DPS from d 0 to 7 after weaning. Pigs fed the S6D3 diet showed better weight gain and feed intake than other treatments, especially compared with pigs fed S3D6 diet (p<0.05) from d 8 to 21 after weaning. For the overall experimental period, pigs fed the S6D3 diet showed the best improvement in ADG and ADFI. The digestibilities of dry matter (DM) and crude protein (CP) were higher in pigs fed the S6D6 diet than other diets from d 0 to 7 after weaning. However, pigs fed S6D3 diet showed higher DM, CP and essential amino acids (except methionine and arginine) digestibilities than pigs fed other diets from d 8 to 21 after weaning, although there was no significant difference. From d 8 to 21 after weaning, threonine, valine, isoleucine and leucine digestibilites were higher in S6D6 group, and phenyalanine, histidine, lysine and arginine digestibility were higher in S6D3 group than other groups. The ratio of CD4 and CD8 positive lymphocytes during the overall experimental period was independent of the ratio of SDPP and DPS. However, CD4+:CD8+ ratio was numerically lowered in pigs fed diet the S6D3 diet. Therefore, the present study suggests that an optimal inclusion ratio for maximizing growth performance and maintaining low immune status is 6% of SDPP and 3% of DPS in weaned pigs.

Progress in the development of heating systems towards long pulse operation for KSTAR

Kwak, J.G.,Bae, Y.D.,Chang, D.H.,Chang, D.S.,Hong, B.G.,Hwang, C.K.,In, S.R.,Jeong, S.H.,Jin, J.T.,Jung, K.S.,Kim, B.R.,Kim, J.,Kim, S.K.,Kim, T.S.,Lee, D.W.,Lee, K.W.,Oh, B.H.,Seo, C.S.,Seo, M.S.,Yoo International Atomic Energy Agency 2007 Nuclear fusion Vol.47 No.5

<P>Construction of the Korea superconducting tokamak advanced research (KSTAR) tokamak is in its final phase. For the long-pulse KSTAR discharges, the ion cyclotron range of frequencies (ICRF) and neutral beam injection (NBI) heating systems are expected to play important roles through a selective heating of ions and electrons, control of the plasma pressure and current profiles, a core fuelling and beam diagnostics for the KSTAR. In addition, the ICRF system is expected to be used for possible discharge cleaning and assisting in the tokamak startup. In this paper, the recent progress in the development of the ICRF and the NBI heating systems is described. The four-strap ICRF antenna has been successfully tested for a voltage up to 41 kV for a pulse length of 300 s (to 46 kV for 20 s) in a test chamber. A prototype KSTAR NBI system has been developed. At present, the system has successfully produced a 1 MW beam power for 200 s and a 3.5 MW output beam power for 4 s.</P>

국산박류의 사료가치에 관한 연구 2 . 부로일러에 대한 박류비교시험

백인기,한인규,김춘수 ( In K . Paik,In K . Han,Chun S . Kim ) 한국축산학회 1975 한국축산학회지 Vol.17 No.4

An experiment was conducted to study the comparative feeding value of locally produced vegetable protein cakes such as soybean oil meal (44%) (S.B.O.M.), rapeseed oil meal (R.O.M.), perilla oil meal (P.O.M.), sesame oil meal (S.O.M.) and corn gluten (50%). Three hundred broiler chickens were used for 8 weeks feeding trial and successive metabolic tiral. Results obtained are as follows; 1. Weight gains were significantly (P$lt;0.01) different among treatments showing the best gain in S.B.O.M. group and then P.O.M., R.O.M., corn gluten and S.O.M. group in that order. Feed intake showed same trend as weight gain did. For the feed efficiency, S.B.O.M. group was significantly (P$lt;0.01) superior to the other groups and S.O.M. group was significantly inferior to the other groups. Among the groups of receiving R.O.M., P.O.M. and corn gluten, differences were not significant each other in feed efficiency. 2. Amino acids compositions of R.O.M. and S.B.O.M. were better than that of other protein feeds considering their relatively high E.A.A. Index of 76.32 and 76.21 respectively. P.O.M., S.O.M. and corn gluten were low in lysine content while methionine contents were relatively high. 3. Nitrogen corrected M.E. values of S.B.O.M., R.O.M., P.O.M., S.O.M. and corn gluten were 2,367㎉, 843㎉, 2.234㎉, 1,305㎉ and 4,283㎉, respectively. Rates of nitrogen retention of P.O.M., S.B.O.M., R.O.M., corn gluten and S.O.M. were 59.38%, 51.18%, 54.11%, 44.80%, and 36.01%, respectively. 4. Dry matter and crude protein availabilities of finisher diet of R.O.M. group and S.B.O.M. group were higher than that of other groups but not significantly different. On the contrary however, crude fat availabilities of R.O.M., and S.B.O.M. group were significantly (P$lt;0.01) lower than that of other groups. 5. Thyroid gland weights and total serum cholesterol contents were significantly (P$lt;0.05) different among treatments. However, the relationship between thyroid gland weight and cholesterol content was observed only in R.O.M. group. Corn gluten was verb effective to increase skin pigmentation. 6. Production cost for 1㎏ of broiler meat of S.B.O.M. group was lower by about 20 won to 30won than that of R.O.M., corn gluten, or P.O.M. group, and by about 100won than that of sesame oil meal group which was least for the performance among the treatments.

In-direct localized surface plasmon resonance (LSPR)-based nanosensors for highly sensitive and rapid detection of cortisol

Jeon, Jinwoo,Uthaman, Saji,Lee, Jiyoung,Hwang, Hyejin,Kim, Gibum,Yoo, Pil J.,Hammock, Bruce D.,Kim, Christine S.,Park, Yeon-Su,Park, In-Kyu Elsevier 2018 Sensors and actuators. B, Chemical Vol.266 No.-

<P><B>Abstract</B></P> <P>Over-secretion of cortisol from the adrenal cortex is closely related to acute and chronic stress; thus, rapid and sensitive detection of cortisol in serum is of critical importance for preventing the progression of stress-related diseases. The binding of a biological molecule to the surface of metallic nanoparticles changes the local refractive index and in turn induces a shift in the localized surface plasmon resonance (LSPR) wavelength. Utilizing this phenomenon, we designed a novel disposable LSPR-based cuvette-type sensor for detecting cortisol in serum. The developed cuvette-type nanosensor consists primarily of an assembly of plastic unit sensors coated with gold nanoparticles on a single layer wherein cortisol-conjugated bovine serum albumin (BSA) is immobilized. In this system, a redshift in LSPR wavelength is induced by the binding of cortisol antibody onto cortisol-conjugated BSA immobilized on a gold nanoparticle surface in the nanosensor. In a competitive assay, the nanosensor could rapidly detect cortisol in both a PBS solution and serum (within 20 min) at concentrations ranging from 1 to 10,000 ng/mL (2.759–3 × 10<SUP>3</SUP> nmol/L), which is comparable to conventional enzyme-linked immunosorbent assay (ELISA) which typically requires longer than 4 h and complex sample preparation. Thus, we demonstrated that the LSPR-based nanosensor system developed in this study can provide a useful toolkit for a rapid, highly sensitive and reliable detection of cortisol hormone in a commercially available manner.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Novel disposable LSPR-based cuvette-type sensor for detecting cortisol in serum. </LI> <LI> Rapid, convenient, and sensitive method for detecting cortisol hormone in serum. </LI> <LI> Detect cortisol in both PBS solution and serum within 20 min at concentrations ranging from 1 to 10,000 ng/mL. </LI> </UL> </P>

반추위 곰팡이의 분리 · 동정과 섬유소 분해효소의 특성구명 및 이들의 산업적 이용에 관한 연구 (4) 한우 및 재래산양의 반추위에서 분리된 곰팡이의 섬유소 분해력 측정

이성실(S . S . Lee),하종규(J . K . Ha),최윤재(Y . J . Choi),한인규(In K . Han),김창현(C . H . Kim),강수현(S . H . Kang) 한국영양사료학회 1995 韓國營養飼料學會誌 Vol.19 No.5

라이신 : DE 비율이 육성된의 성장과 영양소 소화율에 미치는 영향

손광수,김지훈,한인규,정현정 한국축산학회 1999 한국축산학회지 Vol.41 No.4

This experiment was conducted to investigate the effects of energy:amino acid ratio on growth performance and nutrients digestibilities in growing pigs. A total of 180 growing pigs with an average body weight 15.96 ㎏ were randomly allotted into six dietary treatments in a two × three factorial arrangement (two levels of DE; 3,450 (L) and 3,500 (H) kcal DE/㎏ and three energy:amino acid ratios of 2.9 (L), 3.2 (M), 3.5 (H) ㎎ of lysine/㎉ of DE) to determine the optimum ratio of energy:amino acid ratio. For the determination of ileal digestibility, 24 pigs were subjected to a cannulation surgery and involved in a metabolic trial. ADG was not different among dietary groups except between LL and HH group. No significant difference was found between two energy levels, while high Lys:DE resulted in a significant improvement in ADG. Feed intake was not affected by Lys:DE. Digestibility of proximate nutrients generally were not influenced by dietary treatments. Howver, pigs fed HH diets showed significantly higher CP, CF and GE digestibility compared to pigs fed other diets (P$lt; 0.05). Between energy levels, pigs fed high enrgy showed higher digestibility of CP, CF and GE. Among Lys:DE ratios, only CF digestibility responded to increased Lys:DE ratio. The essential amino acids digestibility did not respond to the increase in lysine level in low energy group, while in high energy group average essential amino acids digestibility was increased as the lysine level increased. Pigs fed HH diets showed sinificantly higher lysine and average essential amino acids digestibility. In regard to non-essential amino acid digestibility, generally pigs fed HH diets showed higher value than pigs fed other diets. Between energy levels, digestibility of amino acids did not respond to the increase in energy content except TYR and GLU. However, pigs fed high Lys:DE diet showed higher digestibility in most amino acids except GLU and PRO. Total amino acids digestibility was higher in pigs fed high Lys:DE diet and this result was not consistent to the result of CP digestibility. Based on the result of this study, the optimum Lys:DE ratio was appeared to be higher 3.5 ㎎ lysine/㎉ DE, which is in close agreement with many recent reports.

말라리아박멸을 위한 조사연구 : 1. 말라리아 유행지역 주민의 항체보유율 변화 1. The study for the malaria eradication 1. The seasonal changes of antibodies of inhabitants lived in malaria epidemic areas

김동수,이형우,조신형,인태숙,이혜정,이욱교,김남렬,신민철,문승욱,임현정,고승연,이종수 국립보건연구원 2000 국립보건원보 Vol.37 No.-

Hepatic and splenic sonographic and sonoelastographic findings in pulmonary arterial hypertension

İlhan Hekimsoy,Burçin Kibar Öztürk,Hatice Soner Kemal,Meral Kayıkçıoğlu,Ömer Faruk Dadaş,Gülgün Kavukçu,Mehmet Nurullah Orman,Sanem Nalbantgil,Sadık Tamsel,Hakan Kültürsay,Süha Süreyya Özbek 대한초음파의학회 2021 ULTRASONOGRAPHY Vol.40 No.2

Purpose: The aim of this study was to evaluate the associations of sonographic and sonoelastographic parameters with clinical cardiac parameters, as well as to assess their value in predicting survival in patients with pulmonary arterial hypertension (PAH). Methods: Thirty-six patients with PAH and normal liver function were prospectively enrolled in this prospective study along with 26 healthy controls, all of whom underwent ultrasound and point shear wave elastography examinations. Additionally, the portal vein pulsatility index (PVPI), inferior vena cava collapsibility index, and clinical cardiac variables were obtained in PAH patients. The values of hepatic (LVs) and splenic shear wave velocity (SVs) were compared between PAH patients and controls. The relationships between all sonographic and clinical parameters in the PAH patients were analyzed. Furthermore, their prognostic value in predicting survival was investigated. Results: LVs values in PAH patients (median, 1.62 m/s) were significantly higher than in controls (median, 0.99 m/s), while no significant difference was observed in SVs values. Patients with higher grades of tricuspid regurgitation (TR) had significantly different values of PVPI (P=0.010) and sonoelastographic parameters (P<0.001 for LVs and P=0.004 for SVs) compared to those with less severe TR. Tricuspid annular plane systolic excursion values were the only investigated parameter found to be associated with survival (hazard ratio, 0.814; 95% confidence interval, 0.694 to 0.954; P=0.011). Conclusion: Our results demonstrated a direct association between cardiac congestion (i.e., the severity of TR) and liver stiffness, which should be kept in mind during the assessment of fibrosis in patients with PAH.

Severe Disease Activity Based on the Paris Classification Is Associated with the Development of Extraintestinal Manifestations in Korean Children and Adolescents with Ulcerative Colitis

Jang Hyo-Jeong,Suh Hyo Rim,Choi Sujin,Hong Suk Jin,Cho Seung-Man,Choi Kwang-Hae,Choe Byung-Ho,Kang Ben,Crohn's and Colitis Association in Daegu-Gyeongbuk 대한의학회 2021 Journal of Korean medical science Vol.36 No.44

Background: There are limited data regarding the extraintestinal manifestations (EIMs) associated with pediatric inflammatory bowel disease (IBD) in Korea. We aimed to investigate the clinical features and factors associated with the development of EIMs in Korean children and adolescents with IBD. Methods: This multicenter, retrospective study was conducted from 2010 to 2017. Baseline clinicodemographic, laboratory findings, disease activity, disease phenotypes, and EIMs were investigated. Results: A total of 172 patients were included. One-hundred thirty-seven (79.7%) had Crohn's disease (CD), and 35 (20.3%) had ulcerative colitis (UC). EIMs occurred in 42 patients (24.4%). EIMs developed in 34/137 diagnosed with CD (24.8%), and in 8/35 diagnosed with UC (22.9%), during a median follow-up duration of 3.2 (interquartile range, 1.9–5.4) years for CD and 3.0 (1.0–4.0) years for UC, respectively. Arthritis/arthralgia was most commonly observed (n = 15, 35.7%), followed by stomatitis/oral ulcer (n = 10, 23.8%), hepatitis (n = 5, 11.9%), nephritis (n = 4, 9.5%), pancreatitis (n = 2, 4.8%), erythema nodosum (n = 2, 4.8%), pyoderma gangrenosum (n = 1, 2.4%), primary sclerosing cholangitis (n = 1, 2.4%), uveitis (n = 1, 2.4%), and ankylosing spondylitis (n = 1, 2.4%). A significant difference in disease severity based on the Paris classification (P = 0.011) and ESR at diagnosis (P = 0.043) was observed between the EIM positive and negative group in patients with UC. According to logistic regression analyses, S1 disease severity based on the Paris classification was the only factor that was significantly associated with the development of EIMs (odds ratio, 16.57; 95% confidence interval, 2.18–287.39; P = 0.017). Conclusion: Severe disease activity based on the Paris classification in pediatric patients with UC was significantly associated with EIM development. As disease severity in the Paris classification is a dynamic parameter, treatment should be focused on disease control to minimize the occurrence of EIMs in Korean children and adolescents with UC.

南海島嶼地域에 있어서의 絲狀?症의 疫學的硏究 (Ⅱ)

李溫永,李鍾秀,金東洙,印泰淑,李仁淑,徐炳鍾,金德俊,金東燦 국립보건연구원 1989 국립보건원보 Vol.26 No.