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Abe, Ikue,Hara, Mitsuo,Seki, Takahiro,Cho, Sung June,Shimizu, Masaki,Matsuura, Kazunori,Cheong, Hae-Kap,Kim, Jin Young,Oh, Jihun,Jung, Jaehoon,Han, Mina The Royal Society of Chemistry 2019 Journal of Materials Chemistry C Vol.7 No.8
<P>The design of light-responsive fluorescent assembly systems with a variety of photochemical and photophysical properties is important for the fundamental understanding of the assembly-disassembly process as well as for applications such as optical information storage and fluorescence sensing. A major obstacle in constructing such photofunctional materials is the lack of a molecular design strategy for photoswitchable organic chromophores with aggregation-induced emission/aggregation-induced emission enhancement (AIE/AIEE) characteristics. Herein, we describe a new trigonal azobenzene framework showing AIE/AIEE characteristics and excellent photoisomerization (∼90%) from the <I>C</I>3-symmetric to asymmetric (including a bent-shaped <I>cis</I>-azobenzene) form. NMR experiments demonstrate light-induced molecular structure changes, which cause drastic symmetry breaking. The trigonal chromophores assemble into red fluorescent microspheres and their fluorescence intensity increases by ∼10-fold, confirming the AIE/AIEE characteristics. Importantly, scanning electron microscopy (SEM), optical microscopy (OM), and fluorescence optical microscopy (FOM) images substantiate that a noticeable light-driven melting occurs simultaneously with a marked fluorescence switching from on to off. Moreover, the fluorescent spheres are successfully applied in optical information storage and fluorescence sensing in a non-contact fashion.</P>
Takuya Mino,Yoko Kurosaki,Kana Tokumoto,Takaharu Higuchi,Shinichi Nakanoda,Ken Numoto,Ikue Tosa,Aya Kimura-Ono,Kenji Maekawa,Tae Hyung Kim,Takuo Kuboki 대한치과보철학회 2022 The Journal of Advanced Prosthodontics Vol.14 No.4
PURPOSE. The aim of this study was to introduce rating criteria to evaluate student performance in a newly developed, digital wax-up preclinical program for computer-aided design (CAD) of full-coverage crowns and preliminarily investigate the reliability and internal consistency of the rating system. MATERIALS AND METHODS. This study, conducted in 2017, enrolled 47 fifth-year dental students of Okayama University Dental School. Digital wax-up training included a fundamental practice using computer graphics (CG), multipurpose CAD software programs, and an advanced practice to execute a digital waxup of the right mandibular second molar (#47). Each student’s digital wax-up work (stereolithography data) was evaluated by two instructors using seven qualitative criteria. The total qualitative score (0-90) of the criteria was calculated. The total volumetric discrepancy between each student’s digital wax-up work and a reference prepared by an instructor was automatically measured by the CAD software. The inter-rater reliability of each criterion was analyzed using a weighted kappa index. The relationship between the total volume discrepancy and the total qualitative score was analyzed using Spearman’s correlation. RESULTS. The weighted kappa values for the seven qualitative criteria ranged from 0.62 - 0.93. The total qualitative score and the total volumetric discrepancy were negatively correlated (ρ = -0.27, P = .09, respectively); however, this was not statistically significant. CONCLUSION. The established qualitative criteria to evaluate students’ work showed sufficiently high inter-rater reliability; however, the digitally measured volumetric discrepancy could not sufficiently predict the total qualitative score.
개에 있어서 중증(重症)의 판막상성(瓣上性) 및 판막성폐동맥협착증(瓣性肺動脈狹窄症)에 대한 심박동정지하 (心停止下) 심장막패치법에 의한 1 치험례(治驗例)
백영기(번역자),長屋好昭(Yoshiaki NAGAYA),金本 勇(Isamu KANEMOTO),千村?一(Syuichi CHIMURA),益本友成(Tomonari MASUMOTO),小原公成(Kiminari OHARA),伊藤裕二(Yuji ITO),猪股直美(Naomi INOMATA),竹島昌俊(Masatoshi TAKESHIMA),田中郁江(Ikue TANAKA) 로얄에이알씨 주식회사 2004 로얄동물임상의학 Vol.2 No.4
4개월령 때의 예방접종을 위한 진찰에서 수축기잡음이 청취되었던 1세령의 암컷, 체중 3㎏의 치와와가 각종의 검사에서 중증의 판막상성(瓣上性)-판막성(瓣性)폐동맥협착증으로 진단되었다. 이 증례에 대하여 표면냉각단순저체온마취(表面冷却單純低體溫麻醉)에의한 심장박동 정지하(停止下)에서의 심장막 패치법(Patch method)으로 외과수술을 실시하여 교정에 성공하였다. 수술 후에는 X선 검사에 의하여 심흉격비율(心胸隔比)의 축소와 우심실압(右心室壓)의 저하가 인정되었다. In a one-year-old female Chihuahua, weighing 3㎏, which had shown a systolic murmur at the examination of vaccination at 4 months of age, we diagnosed several supravalvular and valvular pulmonic stenoses using various examinations. Our surgical treatment with the pericardial path-method under cardiac arrest succeeded using simple surface hypothermia. The treatment induced a reduction of the cardiothoracic ratio in radiographic examination and decline of right ventricle pressure after operation.
Iku Abe,Takahiro Kinoshita,Akio Kaito,Hideki Sunagawa,Masahiro Watanabe,Shizuki Sugita,Akiko Tonouchi,Reo Sato 대한위암학회 2017 Journal of gastric cancer Vol.17 No.2
The role of nodal station No. 14v (along the superior mesenteric vein) in lymphadenectomy for distal gastric cancer remains elusive. A 73-year-old woman underwent endoscopic submucosal dissection for gastric cancer, and was referred to our division for additional surgery because of pathologically non-curative resection. A laparoscopic distal gastrectomy with D1+ dissection was performed, with a final diagnosis of pT1bN1M0, Stage IB (2 nodal metastases to No. 6). Four months post-surgery, abdominal computed tomography revealed a 14-mm solitary nodule along the superior mesenteric vein. The lesion was excised and pathologically identified as a lymph node metastasis. Adjuvant chemotherapy with tegafur- gimeracil-oteracil potassium (S-1) was administered for the metastasis. Presently the patient survives without recurrence, 5.5 years after the second operation. Our findings suggest that there is lymphatic flow from the No. 6 to the No. 14v nodal station. Some patients with a No. 6 metastasis may benefit from a No. 14v lymphadenectomy, even in early-staged disease.
Aboh Iku Kisani,Ageh Nonye Immaculate,Saganuwan Alhaji Saganuwan 경희대학교 융합한의과학연구소 2023 Oriental Pharmacy and Experimental Medicine Vol.23 No.3
Lignocaine is a local anaesthetic used in castration of dogs. However, lignocaine is sometimes combined with adrenaline in order to prolong the anaesthetic efect. Either lignocaine or lignocaine-adrenaline combination is associated with toxicity efects. Hence, anaesthetic potentials of lignocaine, lignocaine-adrenaline, fruit and stem-bark aqueous extract of Annona muricata were comparatively studied during castration in Nigerian indigenous dogs. Twelve adult dogs of about 1.00±0.00-year-old and weighing 8.8±0.4 kg divided into four groups of three each were used. The four groups were administered 2% lignocaine, lignocaine-adrenaline, fruit and stem-bark aqueous extracts each, at a dose of, 7.5 mg/kg each, by infltration on the scrotal sac. After loss of sensation, ochidectomy was carried out. Time of onset and duration of anaesthesia were signifcantly higher (p<0.05) in stem bark and fruit extract groups as compared to lignocaine and lignocaineadrenaline groups. More so duration of anaesthesia was higher in lignocaine-adrenaline as compared to adrenaline. The fndings have shown that lignocaine and lignocaine-adrenaline could increase whereas stem bark and fruit extract could decrease respiratory rate, respectively. Highest duration of anaesthesia was observed in stem- bark extract anaesthetized dogs followed by fruit extract treated group in comparison with lignocaine-adrenaline and lignocaine treated groups. Time of onset of anaesthesia was longest in fruit extract treated group and shortest in lignocaine and lignocaine-adrenaline treated groups respectively. Lignocaine and lignocaine/adrenaline increased and decreased haematological parameters, respectively. Lignocaine, lignocaine-adrenaline and the extracts altered biochemical parameters. Hence, Annona muricata could serve as potent local anaesthetic agent.