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Iku Abe,Takahiro Kinoshita,Akio Kaito,Hideki Sunagawa,Masahiro Watanabe,Shizuki Sugita,Akiko Tonouchi,Reo Sato 대한위암학회 2017 Journal of gastric cancer Vol.17 No.2
The role of nodal station No. 14v (along the superior mesenteric vein) in lymphadenectomy for distal gastric cancer remains elusive. A 73-year-old woman underwent endoscopic submucosal dissection for gastric cancer, and was referred to our division for additional surgery because of pathologically non-curative resection. A laparoscopic distal gastrectomy with D1+ dissection was performed, with a final diagnosis of pT1bN1M0, Stage IB (2 nodal metastases to No. 6). Four months post-surgery, abdominal computed tomography revealed a 14-mm solitary nodule along the superior mesenteric vein. The lesion was excised and pathologically identified as a lymph node metastasis. Adjuvant chemotherapy with tegafur- gimeracil-oteracil potassium (S-1) was administered for the metastasis. Presently the patient survives without recurrence, 5.5 years after the second operation. Our findings suggest that there is lymphatic flow from the No. 6 to the No. 14v nodal station. Some patients with a No. 6 metastasis may benefit from a No. 14v lymphadenectomy, even in early-staged disease.
Abe, Iku,Kinoshita, Takahiro,Kaito, Akio,Sunagawa, Hideki,Watanabe, Masahiro,Sugita, Shizuki,Tonouchi, Akiko,Sato, Reo The Korean Gastric Cancer Association 2017 Journal of gastric cancer Vol.17 No.2
The role of nodal station No. 14v (along the superior mesenteric vein) in lymphadenectomy for distal gastric cancer remains elusive. A 73-year-old woman underwent endoscopic submucosal dissection for gastric cancer, and was referred to our division for additional surgery because of pathologically non-curative resection. A laparoscopic distal gastrectomy with D1+ dissection was performed, with a final diagnosis of pT1bN1M0, Stage IB (2 nodal metastases to No. 6). Four months post-surgery, abdominal computed tomography revealed a 14-mm solitary nodule along the superior mesenteric vein. The lesion was excised and pathologically identified as a lymph node metastasis. Adjuvant chemotherapy with tegafur-gimeracil-oteracil potassium (S-1) was administered for the metastasis. Presently the patient survives without recurrence, 5.5 years after the second operation. Our findings suggest that there is lymphatic flow from the No. 6 to the No. 14v nodal station. Some patients with a No. 6 metastasis may benefit from a No. 14v lymphadenectomy, even in early-staged disease.
Aboh Iku Kisani,Ageh Nonye Immaculate,Saganuwan Alhaji Saganuwan 경희대학교 융합한의과학연구소 2023 Oriental Pharmacy and Experimental Medicine Vol.23 No.3
Lignocaine is a local anaesthetic used in castration of dogs. However, lignocaine is sometimes combined with adrenaline in order to prolong the anaesthetic efect. Either lignocaine or lignocaine-adrenaline combination is associated with toxicity efects. Hence, anaesthetic potentials of lignocaine, lignocaine-adrenaline, fruit and stem-bark aqueous extract of Annona muricata were comparatively studied during castration in Nigerian indigenous dogs. Twelve adult dogs of about 1.00±0.00-year-old and weighing 8.8±0.4 kg divided into four groups of three each were used. The four groups were administered 2% lignocaine, lignocaine-adrenaline, fruit and stem-bark aqueous extracts each, at a dose of, 7.5 mg/kg each, by infltration on the scrotal sac. After loss of sensation, ochidectomy was carried out. Time of onset and duration of anaesthesia were signifcantly higher (p<0.05) in stem bark and fruit extract groups as compared to lignocaine and lignocaineadrenaline groups. More so duration of anaesthesia was higher in lignocaine-adrenaline as compared to adrenaline. The fndings have shown that lignocaine and lignocaine-adrenaline could increase whereas stem bark and fruit extract could decrease respiratory rate, respectively. Highest duration of anaesthesia was observed in stem- bark extract anaesthetized dogs followed by fruit extract treated group in comparison with lignocaine-adrenaline and lignocaine treated groups. Time of onset of anaesthesia was longest in fruit extract treated group and shortest in lignocaine and lignocaine-adrenaline treated groups respectively. Lignocaine and lignocaine/adrenaline increased and decreased haematological parameters, respectively. Lignocaine, lignocaine-adrenaline and the extracts altered biochemical parameters. Hence, Annona muricata could serve as potent local anaesthetic agent.
Abe, Ikue,Hara, Mitsuo,Seki, Takahiro,Cho, Sung June,Shimizu, Masaki,Matsuura, Kazunori,Cheong, Hae-Kap,Kim, Jin Young,Oh, Jihun,Jung, Jaehoon,Han, Mina The Royal Society of Chemistry 2019 Journal of Materials Chemistry C Vol.7 No.8
<P>The design of light-responsive fluorescent assembly systems with a variety of photochemical and photophysical properties is important for the fundamental understanding of the assembly-disassembly process as well as for applications such as optical information storage and fluorescence sensing. A major obstacle in constructing such photofunctional materials is the lack of a molecular design strategy for photoswitchable organic chromophores with aggregation-induced emission/aggregation-induced emission enhancement (AIE/AIEE) characteristics. Herein, we describe a new trigonal azobenzene framework showing AIE/AIEE characteristics and excellent photoisomerization (∼90%) from the <I>C</I>3-symmetric to asymmetric (including a bent-shaped <I>cis</I>-azobenzene) form. NMR experiments demonstrate light-induced molecular structure changes, which cause drastic symmetry breaking. The trigonal chromophores assemble into red fluorescent microspheres and their fluorescence intensity increases by ∼10-fold, confirming the AIE/AIEE characteristics. Importantly, scanning electron microscopy (SEM), optical microscopy (OM), and fluorescence optical microscopy (FOM) images substantiate that a noticeable light-driven melting occurs simultaneously with a marked fluorescence switching from on to off. Moreover, the fluorescent spheres are successfully applied in optical information storage and fluorescence sensing in a non-contact fashion.</P>