Long-term assessment of periodontal disease progression after surgical or non-surgical treatment: a systematic review

Ignacio Sanz-Martín,Jae-Kook Cha,윤성욱,Ignacio Sanz-Sánchez,정의웅 대한치주과학회 2019 Journal of Periodontal & Implant Science Vol.49 No.2

The primary aim of this systematic review was to assess the evidence on periodontal disease progression after treatment in patients receiving supportive periodontal therapy (SPT) and to identify predictors of clinical attachment level (CAL) loss. A protocol was developed to answer the following focused question: In adult patients treated for periodontitis, what is the disease progression in terms of CAL loss after surgical or non-surgical treatment? Randomized controlled clinical trials, prospective cohort studies, and longitudinal observational human studies with a minimum of 5 years of follow-up after surgical or non-surgical treatment that reported CAL and probing depth changes were selected. Seventeen publications reporting data from 14 investigations were included. Data from 964 patients with a follow-up range of 5–15 years was evaluated. When the CAL at the latest follow-up was compared to the CAL after active periodontal therapy, 10 of the included studies reported an overall mean CAL loss of ≤0.5 mm, 3 studies reported a mean CAL loss of 0.5–1 mm, and 4 studies reported a mean CAL loss of >1 mm. Based on 7 publications, the percentage of sites showing a CAL loss of ≥2 mm varied from 3% to 20%, and a high percentage of sites with CAL loss was associated with poor oral hygiene, smoking, and poor compliance with SPT. The outcomes after periodontal therapy remained stable over time. Disease progression occurred in a reduced number of sites and patients, mostly associated with poor oral hygiene, poor compliance with SPT, and smoking.

"Do they see me as a Professional?”: Narratives of an Early Childhood Teacher in the Context of COVID-19 Pandemic

Figueroa-Céspedes Ignacio(Figueroa-Céspedes Ignacio),Guerra Paula(Guerra Paula) The Pacific Early Childhood Education Research Ass 2024 Asia-Pacific journal of research in early childhoo Vol.18 No.1

This article analyses the experience of a Chilean early childhood (EC) teacher in the context of the COVID-19 pandemic. Part of a broader qualitative and narrative research, this article is a case study based on her professional experience during the pandemic. The results reveal four phases in the process: (1) initial confusion, (2) proposal, (3) disappointment and action, (4) balance and dialogue. The narrative shows a series of situations experienced by the EC teacher in her relationship with the children’s families, where identity negotiation emerged linked to the revalidation of her professional role. In addition, developing teaching and collaborative skills to respond to emergency situations is highlighted. Based on this experience, the need to elicit cultural changes that articulate care and pedagogical fields in EC education in Chile is analysed.

Unilateral Cervical Facet Fractures: Relevance of Acute Disc Injury in Conservative Treatment Failure

Totera Juan Ignacio Cirillo,Vargas Gabriel Hernández,Martini Ignacio Farías,Romero Marcos Gimbernat,Bacciarini Alejandro Urzúa,Plaza José Vicente Ballesteros 대한척추외과학회 2023 Asian Spine Journal Vol.17 No.1

Study Design: Case-control study. Purpose: Analyze association between imaging factors related to the failure of conservative treatment in isolated subaxial cervical facet fractures. Overview of Literature: Facet fracture (F1, F2, and F3 AOSpine) may be stable or unstable depending on clinical and imaging variables, which are not well established. As a result, differences in fracture management lead to differences in surgical or conservative indications, and there is no evidence to predict conservative treatment failure. Methods: Patients were categorized into two groups: six patients (16.2%) with conservative treatment failure (defined as the appearance of neurological symptoms, listhesis >3.5 mm, kyphotic deformation >11°, and/or non-union), and 31 patients (83.7%) with successful conservative management (defined as complete consolidation confirmed by computed tomography [CT] at the 6-month follow-up). All participants were fitted with rigid collars of the Miami type, and standardized follow-up was performed until consolidation or failure. CT and magnetic resonance imaging (MRI) was used to examine imaging characteristics. Sagittal balance parameters were assessed using CT, and signs of acute disc injury, prevertebral edema, facet synovitis, and interspinous hyperintense signal were assessed using MRI. Results: Thirty-seven patients were diagnosed with unilateral cervical facet fractures between 2009 and 2020. In this sample, acute disc injury had a significative association to failure of conservative treatment in F2 and F3 AOSpine facet fractures, 100% of the failure group presented with traumatic disc injury compared to 9.7% of the successful group, for the other variables: prevertebral edema, 83.7% vs. 41.9%; facet synovitis, 100% vs. 77.4%; and interspinous hyperintensity, 71.4% vs. 38.7%, respectively. With conservative management, all F1 fractures healed successfully. Conservative treatment failed in 20% of F2 fractures and 50% of F3 fractures, respectively. In terms of cervical sagittal balance parameters, there were no significant differences between groups. Conclusions: Conservative management was successful in all F1 fractures. In F2 and F3 types, there was a significant association between acute disc injury and conservative treatment failure.

Long-term assessment of periodontal disease progression after surgical or non-surgical treatment: a systematic review

Sanz-Martin, Ignacio,Cha, Jae-Kook,Yoon, Sung-Wook,Sanz-Sanchez, Ignacio,Jung, Ui-Won Korean Academy of Periodontology 2019 Journal of Periodontal & Implant Science Vol.49 No.2

The primary aim of this systematic review was to assess the evidence on periodontal disease progression after treatment in patients receiving supportive periodontal therapy (SPT) and to identify predictors of clinical attachment level (CAL) loss. A protocol was developed to answer the following focused question: In adult patients treated for periodontitis, what is the disease progression in terms of CAL loss after surgical or non-surgical treatment? Randomized controlled clinical trials, prospective cohort studies, and longitudinal observational human studies with a minimum of 5 years of follow-up after surgical or non-surgical treatment that reported CAL and probing depth changes were selected. Seventeen publications reporting data from 14 investigations were included. Data from 964 patients with a follow-up range of 5-15 years was evaluated. When the CAL at the latest follow-up was compared to the CAL after active periodontal therapy, 10 of the included studies reported an overall mean CAL loss of ${\leq}0.5mm$, 3 studies reported a mean CAL loss of 0.5-1 mm, and 4 studies reported a mean CAL loss of >1 mm. Based on 7 publications, the percentage of sites showing a CAL loss of ${\geq}2mm$ varied from 3% to 20%, and a high percentage of sites with CAL loss was associated with poor oral hygiene, smoking, and poor compliance with SPT. The outcomes after periodontal therapy remained stable over time. Disease progression occurred in a reduced number of sites and patients, mostly associated with poor oral hygiene, poor compliance with SPT, and smoking.

Pulmonary Embolism from Cement Augmentation of the Vertebral Body

Jose Manuel Fernando Ignacio,Katrina Hannah Dizon Ignacio 대한척추외과학회 2018 Asian Spine Journal Vol.12 No.2

Pulmonary cement embolism (PCE) can follow cement augmentation procedures for spine fractures due to osteoporosis, traumatic injuries, and painful metastatic lesions. PCE is underreported and it is likely that many cases remain undiagnosed. Risk factors for PCE have been identified, which can help alert clinicians to patients likely to develop the condition, and there are recommended techniques to reduce its incidence. Most patients with PCE are asymptomatic or only develop transient symptoms, although a few may exhibit florid cardiorespiratory manifestations which can ultimately be fatal. Diagnosis is mainly by radiographic means, commonly using simple radiographs and computed tomography scans of the chest with ancillary tests that assess the patient’s cardiorespiratory condition. Management depends on the location and size of the emboli as well as the patient’s symptomatology. The aim of this review is to raise awareness of the not uncommon complications of PCE following vertebral cement augmentation and the possibility of serious sequelae. Recommendations for the diagnosis and management of PCE are presented, based on the most recent literature.

La antig?edad cl?sica como fuente y contexto en El esclavo en grillos de oro de Bances Candamo

Ignacio L?pez-Calvo 한국스페인어문학회 2006 스페인어문학 Vol.0 No.41

La antigüedad clásica sirve de trasfondo a la comedia El esclavo en grillos de oro en donde el dramaturgo aurisecular Francisco Bances Candamo(1662-1704)refleja sus inquietudes políticas. Con la presentación de los enredos políticos del imperio romano, el dramaturgo asturiano consigue que el lector-espectador tome conciencia de la sombra amenazadora que acosa a la monarquía de Carlos II el Hechizado (1661-1700), dada la ausencia de heredero. La crítica ha mencionado varios tratados destinados a la educación de príncipes. Sin embargo, no se ha mencionado nunca un texto que parece haber tenido también mucha influencia en su obra: la "Oración" a Nicocles, rey de Chipre, de Isócrates. En El esclavo en grillos de oro, además del esperado panegírico al rey, encontramos una osadía que acabaría costando muy cara a su autor. Como Isócrates, Bances Candamo tratade educar al rey para el buen gobierno e incluso se atreve a volver a mencionar el tema tabú de la sucesión. Al instar indirectamente al rey a que buscara un heredero para España, y al criticar a los allegados al emperador romano, la corte lo consideró una afrenta tanto al rey como al privado de Carlos II. De hecho, tras ser herido en el pecho por un espectador que vio en El esclavo en grillos de oro un ataque al Conde de Oropesa, privado del rey, Bances Candamo se vio obligado, como se mencionó anteriormente, a dejar su cargo y huir de Madrid por un tiempo.

Numerical and experimental analysis of a wave energy converter in extreme waves

Ignacio P. Johannesen,Jose M. Ahumada,Gonzalo Tampier,Laura Gruter,Cristian Cifuentes Techno-Press 2023 Ocean systems engineering Vol.13 No.3

In the present paper, a numerical and experimental analysis for a wave energy converter under extreme environmental conditions is carried out. After the definition of design waves, including a 100-year return period stochastic sea state and a deterministic rogue wave condition, a numerical analysis using potential theory and a RANS equations solver are compared with experiments carried out at the Seakeeping Basin at the Technical University of Berlin. Results are discussed with special emphasis on the limits of potential theory methods for the evaluation of extreme wave conditions and the use of the presented methodology for early design stages.

Therapeutic effect of Active Hexose-Correlated Compound (AHCC) combined with CpG-ODN (oligodeoxynucleotide) in B16 melanoma murine model

Ignacio, R.M.,Kim, C.S.,Kim, Y.D.,Lee, H.M.,Qi, X.F.,Kim, S.K. Saunders Scientific Publications, W.B. Saunders ; 2015 Cytokine Vol.76 No.2

While Active Hexose Correlated Compound (AHCC) and CpG oligodeoxynucleotide (ODN) are separately known to modulate oxidative stress and immune responses in cancer patients, the combined effect of these two compounds is unknown. To clarify this, we investigated whether AHCC plus KSK-CpG ODN would be therapeutic in B16 melanoma mouse model, if so, and how in reduction-oxidation (redox) balance and cytokines network. We found that treatment groups (AHCC only, KSK-CpG ODN only and AHCC/KSK-CpG ODN) markedly reduced (p<0.001) tumor size when compared to the positive control (PC) group. The total white blood cell (WBC) of AHCC only and KSK-CpG ODN only-treated groups showed significant lower counts than that of PC group. Next, the production of nitric oxide (NO) was significantly increased (p<0.01) in AHCC/KSK-CpG ODN group compared to the PC group. Further, the redox balance was improved in AHCC/KSK-CpG ODN group through significantly low (p<0.001) reactive oxygen species (ROS) production and significantly high (p<0.05) glutathione peroxidase (GPx) activity compared to the PC group. Finally, AHCC/KSK-CpG ODN (p<0.01) and KSK-CpG ODN (p<0.001)-treated groups augmented tumor immune surveillance as shown by significantly increased level of anti-inflammatory cytokine (IL-10) and significantly decreased (p<0.05) level of pro-tumorigenic IL-6 of AHCC/KSK-CpG ODN treated group as compared to the PC group. Collectively, our study indicates therapeutic effect of Active Hexose-Correlated Compound (AHCC) combined with KSK-CpG ODN in B16 melanoma murine model via balancing redox and cytokines network.

Use of intraoperative impression smear cytology to guide successful treatment of a large renal cyst in a dog: a case report

Ignacio Otero Balda,Michail Vagias,Joseph Cassidy,Peter J. O’Brien,Ronan A. Mullins 대한수의학회 2022 Journal of Veterinary Science Vol.23 No.2

A 13-yr-old Shih tzu was referred for surgical management of right-sided cranial abdominal mass, which corresponded to large, cavitated renal mass on ultrasonography, and was suspected to represent neoplasia. Intraoperative impression smear cytology (ISC) of the renal mass wall was consistent with benign renal cyst (RC), without evidence of neoplasia or infection. Deroofing and omentalisation were performed and histopathology was consistent with benign RC. Chronic kidney disease was diagnosed 4 mon postoperatively, however, the dog was asymptomatic, without cyst reoccurrence. Intraoperative ISC is an expedient and inexpensive diagnostic technique that can guide most appropriate treatment in dogs with large RCs.

La antiguedad clasica como fuente y contexto en El esclavo en grillos de oro de Bances Candamo

( Ignacio Lopez Calvo ) 한국스페인어문학회 2006 스페인어문학 Vol.0 No.41

La antiguedad clasica sirve de trasfondo a la comedia El esclavo en grillos de oro en donde el dramaturgo aurisecular Francisco Bances Candamo(1662-1704)refleja sus inquietudes politicas. Con la presentacion de los enredos politicos del imperio romano, el dramaturgo asturiano consigue que el lector-espectador tome conciencia de la sombra amenazadora que acosa a la monarquia de Carlos II el Hechizado (1661-1700), dada la ausencia de heredero. La critica ha mencionado varios tratados destinados a la educacion de principes. Sin embargo, no se ha mencionado nunca un texto que parece haber tenido tambien mucha influencia en su obra: la Oracion a Nicocles, rey de Chipre, de Isocrates. En El esclavo en grillos de oro, ademas del esperado panegirico al rey, encontramos una osadia que acabaria costando muy cara a su autor. Como Isocrates, Bances Candamo tratade educar al rey para el buen gobierno e incluso se atreve a volver a mencionar el tema tabu de la sucesion. Al instar indirectamente al rey a que buscara un heredero para Espana, y al criticar a los allegados al emperador romano, la corte lo considero una afrenta tanto al rey como al privado de Carlos II. De hecho, tras ser herido en el pecho por un espectador que vio en El esclavo en grillos de oro un ataque al Conde de Oropesa, privado del rey, Bances Candamo se vio obligado, como se menciono anteriormente, a dejar su cargo y huir de Madrid por un tiempo.