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不純物에 依한 Barium Titanates의 電氣的 性質
박창엽,박상만,김현재,양재면 연세대학교 산업기술연구소 1975 논문집 Vol.6 No.1
Semiconductive Barium Titanates was prepared and its electrical properties were investigated. For the purpose of controlling in valency Al₂O₃, SiO₂, TiO₂ and Sb₂O₃were doped in Barium Titanates as additions. 0.1∼0.2mole% Sb₂O₃ was effective in reducing resistivity of the order of 10³ohm-cm. Semiconductive Barium Titanates showed anomalous positive character in the temperature dependency of resistivity. It is proposed that conduction in those samples is caused by exchanging electrons between ?? ions and ?? ions.
아동들의 태권도 수련활동참가에 따른 열등감 및 자아존중감의 관계
정재엽,정국현,김지영,김현철,이용국 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.2
The purpose of this study was to identify the relationship between children's Inferiority and self-esteem during Taekwondo practice. In order to achieve this purpose, 480 subject were selected among participants of Taekwondo activity programs in the Seoul area by using the stratified cluster random sampling method. Out of the 480 questionnaires responded to. only 414 were used for data analyses because 66 were responded to incompletely or incorrectly. The instrument for data collection was a questionnaire in which Inferiority and self-esteem consisted of items identified by Jun(1999) and Jun(1993), respectively. The statistical methods utilized in the study for analyzing the collected data were reliability analysis, descriptive statistics, one-way ANOVA, standard multiple regression analysis and the following results were obtained: First, both Inferiority and self-esteem differ statistically and significantly according to both sociodemographic variables. Second, both Inferiority and self-esteem differ statistically and significantly according to Taekwondo practice. Third, Inferiority statistically and significantly influences self-esteem.
Hyun-Yub Jung,Yong-Gun Kim,Myoung-Uk Jin,Jin-Hyun Cho,Jae-Mok Lee 대한치과보철학회 2013 The Journal of Advanced Prosthodontics Vol.5 No.1
PURPOSE. The purpose of this study was to to analyze the effect of Type 2 diabetes on tooth mortality, implant treatment and prosthetic status. MATERIALS AND METHODS. 275 Type 2 diabetics and 300 non-diabetics, aged 40-80 years were selected for analysis. The assessment of number of teeth, missing teeth, fixed prostheses (bridge pontics), implants using panoramic radiographs and dental records were carried out. RESULTS. Diabetes mellitus (DM) patients had a higher number of missing teeth (P<.05) and placed implants (P=.074), age (P<.05), male gender percentage (P=.042), smoker percentage (P<.05) than non-DM patients. In univariate analysis, the patients in older group showed significantly higher number of tooth loss rate at the first dental examination than the patients in younger group. Tooth loss rate of smokers did not show higher value than that of non-smokers. When multiple variables including DM, age, smoking, gender were considered together, diabetics and older group patients showed significantly higher tooth loss rate at the first dental examination than non-diabetics and younger group patients, respectively. Smokers and male group did not show a significant difference than nonsmokers and female group, respectively. CONCLUSION. Tooth mortality and implant treatment rate were significantly higher in the DM group as indicated by univariate and multivariate logistic regression analysis. Old age groups showed significantly higher odds ratios and tooth loss rate. As diabetics showed the higher tooth loss rate than non-diabetics, diabetics also had more implant restorations than non-diabetics.
( Hyun Ji Cho ),( Jeong Han Kang ),( Kwan Kyu Park ),( Jung Yoon Choe ),( Yoon Yub Park ),( Yong Suk Moon ),( Ii Kyung Chung ),( Hyeun Wook Chang ),( Cheorl Ho Kim ),( Yung Hyun Choi ),( Wun Jae Kim ) 영남대학교 약품개발연구소 2013 영남대학교 약품개발연구소 연구업적집 Vol.23 No.0
BACKGROUND: Bee venom has been used to relieve pain and to treat inflammatory diseases, including rheumatoid arthritis, in humans. To better understand the mechanisms of the anti-inflammatory and anti-atherosclerosis effect of bee venom, gel electrophoresis and mass spectrometry were used to identify proteins whose expression was altered in human Vascular Smooth Muscle Cells (hVSMCs) stimulated by tumor necrosis factor alpha after 12 h in the presence of melittin. RESULTS: To obtain valuable insights into the anti-inflammatory and anti-atherosclerosis mechanisms of melittin, two-dimensional (2-D) gel electrophoresis and MALDI-TOF/TOF were used. The proteomestudy, we showed 33 significant proteins that were differentially expressed in the cells treated withtumor necrosis factor alpha and melittin. Thirteen proteins were significantly increased in the cells treated with tumor necrosis factor alpha, and those proteins were reduced in the cells treated with melittin. Five of the proteins that showed increased expression in the cells treated with tumor necrosisfactor alpha are involved in cell migration, including calreticulin, an essential factor of development that plays a role in transcription regulation. The proteins involved in cell migration were reduced in the melittin treated cells. The observed changes in the expression of GRP75, prohibitin, and a select group of other proteins were validated with reverse transcribed-PCR. It was confirmed that the observed change in the protein levels reflected a change in the genes level. In addition, the phosphorylation of EGFR and ERK was validated by analyzing the protein pathway. CONCLUSION: Taken together, these data established that the expression of some proteins was significantly changed by melittin treatment in tumor necrosis factor alpha stimulated the cells and provided insights into the mechanism of the melittin function for its potential use as an anti-inflammatory agent.
Jung, Hyun-Yub,Kim, Yong-Gun,Park, Jin-Woo,Suh, Jo-Young,Lee, Jae-Mok Korean Academy of Periodontology 2013 Journal of Periodontal & Implant Science Vol.43 No.2
Purpose: The purpose of this study was to analyze the expression of inducible nitric oxide synthases (iNOS), tissue inhibitors of metalloproteinase $(TIMP)_{-3}$, and $TIMP_{-4}$ in the gingival tissues of periodontal patients with or without type 2 diabetes mellitus (DM). Methods: Depending on the patient's systemic condition and clinical criteria of the gingiva, each gingival sample was classified into one of three groups. Sixteen clinically, systemically healthy patients (group 1), 16 periodontal patients (group 2), and 16 periodontal patients with DM (group 3) were included. Tissue samples in each group were collected, prepared, and analyzed by western blotting. Quantification of the relative amount of $TIMP_{-3}$, $TIMP_{-4}$, and iNOS was performed. Results: The expression levels of iNOS and $TIMP_{-3}$ both increased in group 1, group 2, and group 3 in increasing order, and were significantly higher in both group 2 and group 3 as compared to group 1 (P<0.05). The expression levels of $TIMP_{-4}$ increased in the same order, but significantly increased in group 2 as compared to group 1, in group 3 as compared to group 1, and group 3 as compared to group 2 (P<0.05). Conclusions: This study demonstrated that iNOS, $TIMP_{-3}$, and $TIMP_{-4}$ might be involved in the progression of periodontal inflammation associated with type 2 DM. It is thought that further study of these factors can be applied practically for the diagnosis and control of periodontitis in diabetics.
( Jong Hyun Lee ),( Jung Yub Lee ),( Sang Won Yoon ),( Young Suk Oak ),( Jae Jeong Kim ),( Seung Hyun Kim ) 대한지질공학회 2015 지질공학 Vol.25 No.4
In this study, specific sections vulnerable to debris flow damage were selected, and a complete enumeration survey was performed for the sections with debris flow hazards. Based on this, the characteristics of the sections with debris flow hazards and the current status of actions against debris flow were examined, and an efficient installation plan for a debris flow damage prevention method that is required in the future was suggested. The results indicated that in the Route 56 section where the residential density is relatively higher between the two model survey sections, facilities for debris flow damage reduction were insufficient compared to those in the Route 6 section which is a mountain area. It is thought that several sites require urgent preparation of a facility for debris flow damage reduction. In addition, a numerical analysis showed that for debris barriers installed as a debris flow damage prevention method, distributed installation of a number of small-scale barriers facilities within a valley part was more effective than single installation of a large-scale debris barrier at the lower part of a valley.
Lee, Hyun Jik,Ryu, Jung Min,Jung, Young Hyun,Oh, Sang Yub,Lee, Sei-Jung,Han, Ho Jae AlphaMed Press 2015 Stem Cells Vol.33 No.7
<P>The control of stem cells by oxygen signaling is an important way to improve various stem cell physiological functions and metabolic nutrient alteration. Lipid metabolism alteration via hypoxia is thought to be a key factor in controlling stem cell fate and function. However, the interaction between hypoxia and the metabolic and functional changes to stem cells is incompletely described. This study aimed to identify hypoxia-inducible lipid metabolic enzymes that can regulate umbilical cord blood (UCB)-derived human mesenchymal stem cell (hMSC) proliferation and migration and to demonstrate the signaling pathway that controls functional change in UCB-hMSCs. Our results indicate that hypoxia treatment stimulates UCB-hMSC proliferation, and expression of two lipogenic enzymes: fatty acid synthase (FASN) and stearoyl-CoA desaturase-1 (SCD1). FASN but not SCD1 is a key enzyme for regulation of UCB-hMSC proliferation and migration. Hypoxia-induced FASN expression was controlled by the hypoxia-inducible factor-1 alpha (HIF-1)/SCAP/SREBP1 pathway. Mammalian target of rapamycin (mTOR) was phosphorylated by hypoxia, whereas inhibition of FASN by cerulenin suppressed hypoxia-induced mTOR phosphorylation as well as UCB-hMSC proliferation and migration. RAPTOR small interfering RNA transfection significantly inhibited hypoxia-induced proliferation and migration. Hypoxia-induced mTOR also regulated CDK2, CDK4, cyclin D1, cyclin E, and F-actin expression as well as that of c-myc, p-cofilin, profilin, and Rho GTPase. Taken together, the results suggest that mTORC1 mainly regulates UCB-hMSC proliferation and migration under hypoxia conditions via control of cell cycle and F-actin organization modulating factors. In conclusion, the HIF-1/FASN/mTORC1 axis is a key pathway linking hypoxia-induced lipid metabolism with proliferation and migration in UCB-hMSCs. Stem Cells 2015;33:2182-2195</P>