자궁내막에 발생한 점막 연관 림프조직 (MALT) 림프종 1예

전균호,조현진,박성균,김천복,김대연,김종혁,김용만,김영탁,목정은,남주현 대한부인종양 콜포스코피학회 2003 Journal of Gynecologic Oncology Vol.14 No.4

Non-Hodgkin's 림프종의 약 40%는 결절외(extranodal) 림프종으로 대개 위장관에서 발생하며 이들 중 점막 연관 림프조직(mucosa-associated lymphoid tissue: MALT)에서 기원한 림프종은 MALT 림프종으로 분류된다. 위 외의 부위에서 원발성으로 발생하는 MALT 림프종은 매우 드물지만 실제 거의 모든 신체 장기에 발생하는 것으로 알려져 있는데, 가장 흔한 부위인 위 외에도 폐, 갑상선, 침샘, 눈물샘에 발생하고, 드물게 안구, 유방, 방광, 신장, 흉선 등에도 보고된 바 있다. MALT 림프종은 오랜 기간동안 원격 전이하지 않고 국소 병변으로 남아 있는 특징이 있어 치료 방향 또한 국소 병변의 치료에 집중되며, 예후도 림프절 기원의 림프종에 비해 양호한 것으로 알려져 있다. 본 저자 등은 자궁 내막에 원발성으로 발생한 MALT 림프종 1예를 경험하였기에 문헌 고찰과 함께 이를 보고하고자 한다. Mucosa associated lymphoid tissue (MALT) lymphoma can rarely develop primarily in extranodal sites other than stomach which is the most common site for it. Other rare primary sites are small intestine, colorectum, esophagus, lung, thyroid, salivary gland, lacrymal gland, breast and skin. MALT lymphoma represents a distinct clinicopathologic features: it is usually localized to their original site for a long time and shows much more favorable prognosis than lymphoma at other site, but some MALT lymphoma can arise simultaneously or successively in different organ or give rise to another MALT lymphoma of other organ and can be multifocally disseminated or recurred. We report a very rare case of high grade B-cell lymphoma of mucosa associated lymphoid tissue (MALT) of the uterine endometrium, which was confirmed by immunohistochemical assay.

원문 : 좌업 시간과 알코올 섭취가 30대 남자 사무직 근로자의 혈압과 혈관탄성에 미치는 영향

조봉오 ( Bong Oh Cho ),이인녕 ( In Yeong Lee ),정균근 ( Gyun Geun Jeong ),장창현 ( Chang Hyun Jang ) 한국운동생리학회(구 한국운동과학회) 2014 운동과학 Vol.23 No.3

조봉오, 이인녕, 정균근, 장창현. 좌업 시간과 알코올 섭취가 30대 남자 사무직 근로자의 혈압과 혈관탄성에 미치는 영향. 운동과학, 제23권 3호, 241-248, 2014. 본 연구의 목적은 일과 중 대부분을 좌업근무 형태로 업무를 수행하고, 스트레스로 인해 음주가 잦고, 운동이 부족한 30대 남자 사무직 음주자 15명을 대상으로 좌업 시간과 알코올 섭취가 혈압과 혈관탄성에 미치는 영향을 분석하여 사무직 근로자에게 건강관리에 필요한 정보를 제공하는데 있다. S대학 운동 생리학 실험실에서 사전 인적 사항과 설문을 작성하고, 신장, 체중, 채혈, 혈압, 혈관탄성, BMI를 측정하였다. 알코올 섭취 횟수, 섭취량, 좌업 시간, 그리고 음주 섭취 전과 후 및 시간대별 (10분, 40분, 60분) 혈압과 혈관탄성의 변화를 측정 분석한 결과를 요약하면 다음과 같다. 1) 평균 좌업시간이 9.87시간, 음주횟수 및 음주량은 월 평균 9.13회와 12.47잔 이였다. 2) 알코올 섭취횟수 및 섭취량에 따른 BMI, TC, LDL-C, HDL-C, 혈압과 혈관탄성 비교에서 알코올 섭취횟수에서 좌상지 혈관탄성은 통계적으로 유의한 차이를 나타냈다(p<.05). 3) 알코올 섭취 전, 후 비교 분석 결과 우상지와 좌상지의 혈관탄성에서 통계적으로 유의한 차이가 나타났다(p<.05). 4) 알코올 섭취 후 시간대별 우상지 혈관탄성은 통계적으로 유의한 차이를 나타냈다(p<.05). 이상의 결과를 종합해 볼 때, 좌업 시간이 혈압과 혈관탄성에 미치는 영향은 통계적으로 유의하게 나타나지 않았고, 알코올 섭취는 혈관탄성에 통계적으로 유의한 차이를 나타냄을 알 수 있었다. 따라서 이는 직장생활의 스트레스를 음주로 해소하는 경향이 있음을 보여주며 건강에 부정적인 영향을 주고 있음을 알 수 있었다. 또한, 신체가 음주에 적응되어 실험 시 섭취한 적은 양(1/2병)은 1회 12.47잔에 비해 혈압과 혈관탄성에 큰 영향을 미치지 못한 것으로 사료된다. Cho, Bong-Oh, Lee, In-Yeong, Jeong, Gyun-Geun, Jang, Chang-Hyun. Effects of Sedentary Occupation Time and Alcohol Intake on Blood Pressure and Vascular Compliance in 30s Male White-Collar Workers. Exercise Science, 23(3): 241-248. 2014. The purpose of this study was to examine effects of duration of sedentary office work and alcohol intake on blood pressure and vascular compliance in male subjects who were office workers aged between 30 to 39 and frequently drink alcoholic beverages to cope with their stress without exercising for health. The study was to provide health-related information necessary for white-collar workers. We collected data of demographic information, height, weight, blood sample, blood pressure, vascular compliance, and BMI from 15 subjects in S University`s Exercise Physiology Laboratory, and analyzed the frequency and amount of alcohol intake, duration of sedentary work, and changes in blood pressure and vascular compliance at diffident time points (10, 40, and 60 minutes post drinking) from baseline. I t was found that the average time of sedentary work was 9.87 hours, drinking 9.13 times a month on average, 12.47 glasses of alcohol beverages per drink. In comparison of BMI, TC, LDL-C, HDL-C, blood pressure and vascular compliance upon the frequency and amount of alcohol intake, the upper left limb`s vascular compliance had a statistically significant difference (p<.05). In the result of the comparative analysis of pre-and post-drinking, vascular compliance was significantly different in the upper right and left limbs (p<.05). Vascular compliance in the upper right limb after drinking significantly changed (p<.05). As a result, the duration of sedentary work had no statistically significant difference in blood pressure and vascular compliance. T he vascular compliance after drinking h ad a statistically significant difference. This suggested that the result was an index that shows the trend of the office workers releasing their work stress by drinking alcoholic beverages, and that drinking had negative impacts on them. In addition, a small amount of intake (a half bottle) at the test time, after the body was adjusted to drinking, compared with 12.47 glasses per intake, had no great impacts on blood pressure and vascular compliance.

정신증적 증상을 보인 장티푸스 1례

손현균 대한생물치료정신의학회 1998 생물치료정신의학 Vol.4 No.2

장티푸스의 여러 합병증 중에 정신증적 증상은 드문 임상양상이다. 장티푸스와 정신증상과의 인과관계는 아직 명확히 알려진 바는 없으나, 장티푸스 환자 중 어떤 화자가 정신증상을 나타내고 어떤 화자는 증상이 나타나지 않는 지에 대해서는 아직 밝혀진 바가 없다. 발병하는데 기여하는 요인으로 장티푸스 감염, 고열, 독소, 대사결핍, 효소 결핍, 비타민 결핍, 소인이 있는 성격 경향 등이 추정된다. 저자는 정신증상을 보인 34세 된 남자 장티푸스 환자를 치료할 기회가 있었고 그 환자는 입원당시에는 정신분열병과 같은 증상을 나타냈었다. 그래서 이에 대한 증례보고와 함께 장티푸스 환자의 정신과적 증상에 대한 문헌고찰을 하여보았다. Among the various complications in typhoid fever, the psychotic symptoms are rare clinical manifestation. The causal relationship between typhoid fever and the psychiatric symptoms is not yet clear. The causative factors of psychiatric symptoms could be the typhoid infection, high fever, toxin, metabolic deficiency, enzymatic defect, vitamin deficiency, predisposing personality. The author experienced a 34 year old male of typhoid fever accompanied with psychotic symptoms, whose symptoms and signs were like that of schizophrenics on admission, and then author reported this patient and reviewed related articles antipsychotics frequently used to relieve psychotic and behavior symptom during acute manic episode before mood stabilizer have an effect on, and it have been suggested that antipsychotics immediately discontinue when to be relieve acute manic symptom is theoretically the best choice.

유치의 치근단 병소에 의해 변위된 영구치의 자발적 맹출

강동균,양승덕,김태완,김현정,김영진,남순현 대한소아치과학회 2007 大韓小兒齒科學會誌 Vol.34 No.2

The infection of primary teeth occurs by caries or trauma. But, if it is not treated on time, the complication may occur such as enamel hypoplasia, discoloration, impaction, displacement and dilaceration of permanent successors. The periapical lesion on primary tooth could displace the permanent successors in any direction. Treatment options of displaced tooth are observation after extracting the primary teeth, surgical exposure, orthodontic traction, transplantation and extraction. In these cases, displacement of permanent central incisor caused by the periapical lesion of primary teeth was observed. The spontaneous eruption after extraction of primary teeth was expected considering degree of displacement, development of root and direction of eruption. This case report shows spontaneous eruption of displaced permanent tooth germ was achieved with periodic examination after extraction of primary teeth.

설계환경을 위한 트랜젝션의 관리에 관한 연구

강현석,김기철,오성균 全北大學校 基礎科學硏究所 1986 基礎科學 Vol.9 No.1

For implementing to design data management in CAD environment, the design transaction must be managed effectively. In this paper, we compared the most known two techniques about this issue. And also we described a design transaction management which is adapted to our proposed design object management system.[8]

방사선을 조사한 생쥐 장기에서의 Superoxide Dismutase 분포에 대한 연구

김양균,전현우,차종희,고광삼,이근배 朝鮮大學校 附設 醫學硏究所 1986 The Medical Journal of Chosun University Vol.11 No.1

The cytosolic and mitochondrial supreoxide dismutases (EC 1.15.1.1) were investigated in various organs, thyroid gland, lung, heart, liver, spleen and kidney, of normal and irradiated mice. The mouse organs were fractionated into cytosolic and mitochondrial fractions by differential centrifugation, and the supsroxidp dismutase was measured by the method of McCord and Fridovich. The mouse organs contain two types of superoxide dismutase ; one is localized in the cytosol and contains cupper and zinc, the other in the mitochondria and contains manganese. Superoxide dismutasc activity was found in all organs of mouse investigated, and maximal activity of enzyme was observed in liver. most of superoxide dismutase activity, 79-86%, was present in the cytosolic fraction, and the rest was associated with mitochondria. The activity of cytosolic superoxide dismutase was most prominent in the liver among those tissues assayed. However, that of mitochoadrial enzyme was highest in the heart. Thc specific activity of superoxide dismutase in mitochondria was found about 2-5 folds greater than that of the enzyme in cytosol and cyanide inhibit the activity of cytosolic enzyme but not mitochondrial enzyme, In irradiatcd mice, the enzyme activity and the specific activity of superoxide dismutase in cytosol and mitochondna of various organs were decreased with minimal value on 7th and l4th day after exposured by whole body-irradiation.

Gas Chromatography를 이용한 멸치젓의 DHA 분석

육현균,하정욱,이승철 慶南大學校 附設 工業技術硏究所 1998 硏究論文集 Vol.16 No.-

멸치젓은 한국의 고유 수산발효식품으로 널리 이용되고 있는 기호식품이다. 멸치젓의 기능성을 살펴보기 위한 기초연구로 기능성 소재인 docosahexaenoic acid (DHA) 함량을 gas chromatorgraphy를 이용하여 분석 하였다. 먼저 산분해법에 의해 고형분의 경우 평균 4,520 ppm 검출되었으며, 액젓의 경우 농축을 하지 않고 산분해법으로 처리한 것과 농축을 한 후 산분해법으로 처리하여 측정한결과 전자는 평균 108 ppm, 후자는 82 ppm으로 검출되었다. 또한 시간이 경과함에 따라 멸치 액젓이 DHA 함량이 감소되어 정확한 검출을 위해서는 항산화제의 첨가가 필요하다. The anchovy-jeot (salt-fermented anchovy) has being widely used as a traditional fish fermented food in Korea. For examining the functional characteristic of the anchovy-jeot, docosahexaenoic acid (DHA) was analyzed by gas chromatography. DHA contents of anchovy solid and anchovy sauce by acidolysis method was 4,520 ppm and 108 ppm, respectively, while that of anchovy sauce by acidolysis method after concentration was 82 ppm. That means that the condition of previous treatment for anchovy sauce would affect the determination of DHA. Furthermore, addition of antioxidant would be needed because DHA of anchovy-jeot was decreased with days by oxidation.

치아 석회화 단계와 골 성숙도 단계간의 상관관계에 대한 연구

강동균,김태완,김영진,남순현,김현정 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.2

본 연구는 성장 중인 부정교합 환자의 진단이나 치료계획의 수립,치료방법 및 시기,예후 등을 결정하는데 중요한 판단 지침이 되는 치아 석회화 단계와 경추 및 수완부골 성숙도간의 연관성을 규명하여 개인의 보다 정확하고 효율적인 사춘기 성장 정도를 평가하기 위해 시행하였다. 전신 질환이 없고 교정 치료 경험이 없는 7-16세의 여아 154명,남아 179 명,총 333명의 파노라마 방사선사진,측모 두부규격 방사선사진,수완부 방사선사진을 분석하여 평가하였다. 연구 결과,파노라마 방사선사진의 치아 석회화 단계를 통하여 사춘기 성장 정도를 평가하는 것은 부정교합 환자의 진단 및 치료계획을 수립하는데 임상적으로 유용한 정보를 제공할 것으로 판단되었다. The purpose of this study was to investigate the relationship between the stages of calcification of various teeth and skeletal maturity stages among Korean individuals. The study subjects consisted 154 female and 179 male ranging from 7 years to 16 years of age. A total of 333 hand-wrist, cephalo-lateral and panoramic radiographs were obtained and analyzed. The tooth development of the mandibular canines, first, second premolars, and second molars were assessed according to the Dermijian' s system. Skeletal maturity stages were determined from hand-wrist radiographs by using the SMI system and cephalo-lateral radiographs by using the CVMS, respectively. The results were as follows 1. The mean ages of each stage of skeletal maturity were consistently younger in female subjects. 2. There was a high correlation between skeletal maturity of hand-wrist and cervical vertebrae in the both sexes. 3. There was a high correlation between skeletal maturity and dental calcification stage of mandibular canines, first premolar, second premolars, and second molar. 4. The mandibular second molar was tooth showing the highest correlation. 5. Percent distributions of the relationship between calcification stages of individual teeth and stages of skeletal maturity were obtained in both sexes. In summary, this suggests that tooth calcification stages from panoramic radiographs might be clinically useful as a maturity indicator of the pubertal growth period.

更年1號丸의 抗酸化活性에 對한 硏究

이현숙,남경수,이태균 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

To investigate the antioxidant effects of Gaengnyounilhohwan (GIH), we administrated acetaminophen (500mg/kg, i.P.) that induced hepatic lipid peroxidation to starved mice for 24hrs after pretreatment of GIH for 6 days. And the effects of GIH on the hepatic enzymes(glutathion-S-transferase, superoxide dismutase, glutathion peroxidase and catala se) which participate in lipid peroxidation and glutathion metabolism were investigated. The results were as follows 1. GST(glutathion-S-transferase) activity in the acetaminphen treated group was remarkably reduced compared with saline treated group (control group). However, in the pretreated group of GIH for 6 days GST activity was increased about 2.7 fold. 2. Compared with control group, SOD (superoxide dismutase) activity was decreased by 26.9% in the acetaminophen treated group. On the other hand, in the GIH pretreated group SOD activity was almost recovered to the level of control group. 3. In the acetaminophen treated group, GSH-Px(glutathion peroxidase) activity was decreased by 47.1 % compare with control group. And in the GIH pretreated group. GSH-Px activity was increased about 2 fold and recover to the control group. 4. Catalase activity was also decreased by 23.8% in actamlnophen treated group. However, in the GIH pretreated group, catalase activity was increased above 2 fold compared with control group. 5. In the acetaminophen treated group, malondialdehyde values of plasma and cytosolic fraction were significantly increased compared with control group. However, after the GIH treated group, lipid peroxide formation was decreased by 47% in plasma, and remarkably decreased 3.7 fold in cytosolic fraction. These results suggest that GIH plays a protective role in the formation of acetaminophen induced lipid peroxidation.

직연신 방사과정에서의 폴리프로필렌 구조해석 : 분자량 및 권취속도에 따른 영향 Effect of Molecular Weight and Take-up Velocity

신현세,이태균 단국대학교 1998 論文集 Vol.33 No.-

Abstrack : The development of the structure of polypropylene fibers during the direct drawing melt spinning process was analyzed by comparing fibers which have gone through the whole direct drawing melt spinning process and fibers in which the drawing step was omitted. The relative contribution of the drawing step was evaluated so that the information on the stages of development of the structure can be utilized as the foundation for future research on functional or high performance fibers. Four different molecular weights and take­up speeds were utilized to study the effect of these variables on the development of the structure. The samples taken up omitting the drawing step were designated as undrawn fibers and the fibers in which the drawing was carried out as drawn fibers. When the properties of the drawn fibers were taken as reference and the degree of structure formation in the undrawn fibers described by the percentage therof, 99, 85 and 95% of the density crystallinity and crystalline orientation had already developed prior to the drawing step. In the other hand the overall orientation was found to be more dependent on the drawing process, with about 64-73% of the orientation being developed in the drawing step and 26.8-36.1% being developed prior to the drawing step. The amorphous orientation of the undrawn fibers exhibited a negative value suggesting that the rotation of lamella to the final structure occurs in the drawing step. The highest tenacity obtained in this experiment was 4.5g/den and the highest modulus 25.4g/den when PP of Mn=230,000 was spun at 800m/min.