볼링후 발생한 전골간신경 증후군-증례 보고-

김혜경,이희숙,박준명,정광익,박동식 大韓再活醫學會 1998 Annals of Rehabilitation Medicine Vol.22 No.4

식도암과 위암이 동시에 발생한 원발성 중복암 1예

윤혜원,심기남,나선경,송도경,정정화,정가영 이화여자대학교 의과학연구소 2012 EMJ (Ewha medical journal) Vol.35 No.2

Double primary cancers are two independently developed cancers in an individual. There have been some reports on double primary cancer since Billroth reported it for the first time in 1879. Double primary cancer of the stomach and esophagus has been revealed a very low incidence worldwide. The incidence of an esophageal cancer with another primary cancer is reported to be 9.5∼27%, but double primary cancers in the esophagus and stomach have been rarely reported to our knowledge. In this study, we present here a case of double primary esophageal and stomach cancer in a 66-year-old man because of progressive dysphagia.

딥러닝 기반 사용자 최적화 스마트 홈 시스템

강경민,함지혜,박동규 순천향대학교 산업기술연구소 2022 순천향 산업기술연구소논문집 Vol.28 No.2

With the 4th industrial revolution IT technologies such as AI and IoT lead the era and AIoT technologies that combine them are currently developing. This paper develops user-optimized smart home system based on deep learning and supplements the security vulnerabilities of IoT services with AES encryption algorithms. The proposed system by this paper implements a deep learning model to learn, predict and provide user-optimized temperatures according to the current temperature and humidity and location. The state of the smart home is divided into automatic and manual and when in automatic mode the cooling and heating system is operated by predicting the user-optimized temperature according to the current temperature, humidity data and the user's location in real time. The smart home proposed by this paper not only increases user convenience but also enables efficient energy management.

[논문] trn L-trn F에 의한 한국 족도리풀속 식물 종 분류

성혜경,허만규,허홍욱 釜山大學校 師範大學 科學敎育硏究所 2011 科學敎育硏究報 Vol.38 No.-

Asarum consists low-growing herbs and is a genus in the Aristo-lochiaceae family with species found in the north temperate zones with most species in Asia. Any species with a highly structured variation pattern must show different distributions of phenotypic characteristics at different locations. I analysed intra- and interspecific phylogenic relationships within genus Asarum in Korea. I evaluated a representative sample of the fourteen taxa (eight Korean taxa and six obtained taxa from GenBank) with the trn L intron and the trn L - trn F spacer region of the chloroplast genome to estimate genetic relationships within genus Asarum. No variable positions were found within the trn L 5` exon and trn L 3` exon. Variable positions within the intron region were mostly distributed outside the structural elements required for intron processing, i.e., not within the first 140 bp at the 5` end and not within the 90 bp at the 3` end of the intron region. Within the spacer region, variable positions were evenly distributed. Alignment of the DNA sequences required adding numerous gaps. Sequence variation within the Asarum is mostly due to nucleotide substitutions, although several small indels and 20 inserts can be found. Another source of sequence divergence is length variation due to stretches of short repeats that occur at the intergenic spacer region ITS2 in all the Asarum. A + T content for eight Korean species of genus Asarum ranged between 64.3% and 64.6%. The base furtherance did not showed the significant difference to the by a total taxon. These values are similar to those (64.5%~67.1%) for the angiosperm alignments of the total trn L and trn F region. The main phylogenetic analysis revealed two distinct clades. The first clade includes ten species (eight Korean species, A. nipponicum, and A. tamaensis). The second clade includes four species (A. canadense , A. cautatum, A. chingchengense , and A. yakusimense). However, some internal nodes are poorly supported. Within Korean Asarum, four species were unsolved portions.

學衝硏究

金惠經 한국중국문화학회 1995 中國學論叢 Vol.4 No.-

양무운동 후기 중국지식인의 서구 의원제에 대한 인식 : 早期維新派를 중심으로

金卿惠 中韓人文科學硏究會 2000 한중인문학연구 Vol.4 No.-

中文要旨 19世紀60年代以後, 淸政府已受到西方列强兩次鴉片戰爭的嚴重打擊, 又受到太平天國和捻軍起義的嚴重威脅.通過內外雙重危機, 淸政府一是親眼看到了西方"船堅砲利"的威力, 二是親身感到階級矛盾的尖銳.正是在面臨"數千年來未有之變局"的背景下, 淸政府部分開明官僚開始興辦洋務, 極力推行練兵制器.70年代中後期, 在多數人眼里, 中國自强的唯一道路仍然是辦洋務, 但 不能應付"地球中之第一大國而受制小夷"的局面, 洋務運動所標榜的"求强","求富"逐漸變成了一句空話.作爲一批先進的知識分子, 早期維新派開始看出洋務運動的一些問題, 批評洋務派的軍事工業是"僅襲皮毛".在尋 自强的出路中, 他們看到了中國與西方的差距, 認識到西方國家之所以富强, 其根本原因在于實行君民共主的議院政治. 他們考察了西方國家政治制度的歷史和現況, 比較了中西政治制度的得失, 認識到中國政治的根本問題卽在封建君主專制制度所造成的 "上下不通"的危害, 于是對封建專制制度進行了大膽的揭露和批判.他們從君民關係, 特別是 "上下不通"的角度來批評封建專制制度.他們認爲, 封建君主專制制度使君,官,民之間隔 太深, 這是造成中國貧困弱後的主要根源.對君主專制制度的懷疑和否定, 使他們向往西方"君民不隔, 上下一心"的議院制度, 進而 主張要想得民心, 挽救民族危機, 就必須變革封建專制制度, 設立議院, 使君民一體, 上下同心.早期維新派在介紹西方議院制時, 賞議院制的兩種作用.第一, 議院是通君民之情者.他們認爲"議院"的作用在于改善封建政治中"君民隔 "的弊病, 其主要目的是爲了"上下相通", "君民一體".第二, 議院是改善官場弊病之道.他們注意到, 由于議院制度的推行, 使西方各國的官僚機構旣不龐大, 又效率顯著, 幾乎沒有淸朝官場中的一切弊病.議院制能根絶官場的一切弊病, 是 因爲具有"公擧","衆寡以爲進退"的良好原則.總之, 西方議院制度是能 實現"公是公非"的合理的社會機制.早期維新派積極宣傳西方議院制的同時, 竝主長在中國實行議院制.不少早期維新派人士都提出了在中國設"議院"的具體方案.他們都認爲西方的模式不太合適中國的情況, 需要有所改變. 何啓,胡禮垣主張把議院與科擧制聯在一起; 陳熾主張把議院制與鄕官制混在一起; 宋恕把議院制與舊官僚制,科擧制混在一起; 湯震主張把議院制與舊官僚機構融爲一體; 陳 把議院制與幕僚制混雜一起.他們對議院的産生,組織,功能等, 都有所討論. 他們所設計議院的目的在于廣開言路, 通上下之情, 而調整和改善君,官,民三者之間的非正常的勸力關係.還有, 他們曾注意到西方政治制度中的三權分立原則, 而初步地介紹進中國來.但他們十分淸楚, 按中國的情況來看, 最需要和有可能實現的, 不是效 西方議院制, 而是建立一 具有"通下情"作用的政治機構.在當時歷史條件下, 早期維新派勇敢地揭露出君,官,民三者之間的非正常的勸力關係, 主張在中國實行"君民共主"的議院制度, 從而改善和調整不均衡的勸力關係.這具有不可忽視的啓蒙意義.

Conjugated Linoleic Acid가 3T3-L1 세포의 증식, 분화, 사멸 및 지질분해에 미치는 영향

김혜경 가톨릭대학교 생활과학연구소 2009 생활과학연구논집 Vol.29 No.1

Conjugated linoleic acid(CLA)는 리놀레산의 위치 및 기하이성질체로 실험동물에서 체지방 증가를 감소시키는 것으로 알려져 있다. 본 연구는 CLA가 지방세포주인 3T3-L1 세포에서 세포 증식, 지방 합성, 세포 사멸 및 지질 분해에 미치는 직접적인 영향을 조사하기 위한 목적으로 실행되었다. 세포는 0.2mM의 α-tocopherol을 함유한 50, 200uM 농도의 CLA 또는 알부민 운반체를 대조군으로 처리하였다. CLA는 지방전구세포의 preconfluent 단계와 postconfluent단계의 증식을 농도의존적으로 억제하였고 성숙한 지방세포의 살아있는 세포 수를 감소시켰다. Postconfluent 단계의 지방전구세포와 성숙한 지방세포는 CLA처리 24시간, 48시간 후에 세포사멸이 관찰되었다. AdipoRed™ 분석법으로 측정한 지방 축적 정도는 CLA에 의해 소폭 감소하는 경향이 있었고, 성숙한 지방세포는 CLA 처리에 의해 기초지질분해가 증가되었다. 이 결과들은 CLA가 지방세포 증식억제, 세포 사멸 유도, 세포 내 지방 축적 감소, 지질 분해에 직접적으로 작용함을 나타낸다. Conjugated linoleic acid(CLA), a group of positional and geometric isomers of linoleic acid, has been shown to decrease body fat gain in rodents. The objective of this study was to determine the direct effects of CLA on proliferation, adipogenesis, apoptosis, and lipolysis in 3T3-L1 adipocytes. Cells were treated with 50, 200 u㏖/L CLA containing 0.2m㏖/L α-tocopherol or bovine serum albumin vehicle as a control. CLA treatment inhibited proliferation of preconfluent and postconfluent preadipocytes dose-dependently and decreased viability of mature adipocytes. Postconfluent preadipocytes and mature adipocytes demonstrated apoptosis after 24 and 48h CLA treatment. Adipogenesis monitored by AdipoRed™ assay was modestly decreased and basal lipolysis was increased by CLA treatment. These results show that CLA decreases fat gain by inhibiting proliferation, inducing apoptosis, attenuating adipogenesis, and promoting lipolysis.

캡슐내시경과 단일풍선 소장내시경으로 진단된 공장의 간질종양 1예

송도경,심기남,태정현,김경진,송명은,송하응,윤혜원,정가영,정정화 이화여자대학교 의과학연구소 2012 EMJ (Ewha medical journal) Vol.35 No.2

Gastrointestinal stromal tumors (GISTs) are common mesenchymal tumors that arise in the wall of the gastrointestinal tract. We report a case of obscure gastrointestinal bleeding due to a GIST of the jejunum successfully documented by videocapsule endoscopy (VCE) and single-balloon enteroscopy (SBE). A 36-year-old man with hematochezia was referred for further evaluation of no evidence of bleeding focus on esophagogastroduodenoscopy and colonoscopy. A VCE showed a suspicious ulcerative hyperemic mass that located in about 1 hour apart from duodenal second portion. SBE revealed a nonbleeding 4×2 cm mass with an ulcer at the proximal jejunum. The patient underwent laparoscopic resection without complication. Histological examination revealed a well circumscribed, dumbbell-shaped firm mass comprised of spindle cells. Immunohistochemical staining for CD 117 was diffusely positive, whereas staining for S-100, CD 34 and MIB-1 was all negative. It was confirmed to be a low-grade GIST at the proximal jejunum.

동진강 정읍천 유역 오염부하량 평가

이경보,김종천,박지혜,이덕배,김종구 한국환경농학회 2004 한국환경농학회지 Vol.23 No.1

하천 수질관리 대안을 제시하고자 동진강에 영향을 가장 크게 미치는 정읍천을 대상으로 2002년 1월부터 2003년 12월까지 점 및 비점 오염원으로부터 수질오염물질의 부하량, 유출 경로 등을 평가하였다. 계절별 수질 변화는 pH 범위가 6.87∼7.53으로 봄의 pH 범위가 컸으 며, EC 농도는 정읍천 중류가 높았으며, 상류유역은 83∼95㎲/㎝ 범위를 나타냈고, 계절별로 가을에 517㎲/㎝로 가장 높았다. BOD의 농도는 상류유역에서 0.61∼1.27 ㎎/L로 Ⅰ급수 수 질은 나타내었으나, 중류와 하류에서는 Ⅲ등급 수준이었다. T-N의 농도는 정읍천 중류 유 역이 6.10∼10.84㎎/L로 가장 높았고, T-P의 농도는 타오염물질에 비해 농도의 편차가 컸으 며, 특히 중류에서 T-P의 농도가 0.41∼0.98 ㎎/L로 높았다. BOD의 배출부하량은 J4 유역에서 553 ㎎/day로 가장 많았고 T-N 발생부화량은 가축, 인 구, 토지이용, 산업의 순으로 컸으며, T-N 배출부하량은 인구 및 산업에 의한 것은 J4 유역, 가축과 토지이용에 의한 부하량은 J5, J6유역에서 높았다. T-N의 유달부하량은 하류 유역에 서 높았으며, T-P의 유달 부하량은 BOD, T-N에 비하여 유달부하량이 낮았고 유달율은 6∼38% 범위를 나타냈다. The influence of pollutant loads on the water quality in Jeongeupcheon of Dongjin river was evaluated from Jan. 2002 to Dec. 2003 for two years. The range of pH in water was 6.87-753. The EC level in upstream ranged from 83 to 95 us/cm with the highest value in autumn. The BOD level in upstream ranged from 0.61 to 1.27 ㎎/L, which would be Ⅰ grade according to water quality criteia by Ministry of Environment, but that in downstream was Ⅲ grade. The average T-N level in midstream range from 6.10 to 10.84㎎/L which was the highest values throughout the stretch of the river. The average T-P levels ranged from 0.41mg to 0.98㎎/L. Jeongeupcheon was suitable for the agricultural usage based upon one year analysis of river water quality. The effluent loads of BOD was high in midstream(J4) with 553 ㎏/day. The major sources of T-N loads were livestock, population, land use, and industry in order. The effluent loads of T-N was high in J4 by population and industry while that of T-N was high in J5 and J6 by livestock and land use. The delivered loads of T-N was high in downstream. The delivered loads of T-P was low as compared with those of BOD and T-N. The delivery ration of T-N ranged from 6 to 38%.

자료포락분석을 통한 직업재활시설의 효율성 분석

이혜경,나운환 한국장애인고용촉진공단 고용개발원 2009 장애와 고용 Vol.19 No.2

20여년의 역사를 지닌 직업재활시설은 중증장애인을 위한 고용과 훈련의 장으로써 역할을 해오고 있으나, 직업재활시설 운영의 효율성에 대하여 실제적으로 연구된 적이 거의 없다. 지금까지 의 직업재활시설 운영에 대한 평가는 단순지표체계에 의한 평가로 정부 예산의 타당성이나 시설 운영에 바람직한 운영방향을 제시하는데에 제한이 있고, 시설 운영의 효율성에 대한 정확한 분석을 얻기 어렵다는 한계가 있다. 따라서 본 연구에서는 자료포락분석을 활용하여 직업재활시설의 상대적 효율성 분석을 통해 직업재활시설이 보다 효율적으로 운영될 수 있는 방안을 제시하고자 하였다. 연구결과 첫째, 종사자 수가 많은 시설일수록 근로장애인들의 월평균 임금이 높으며, 직업재활과정에 따른 사업을 수행하는 시설일수록 재활프로그램 실적, 취업알선 및 취업실적 등의 전반적 실적도 높았으나 상담 및 평가실적과 재활프로그램의 실적이 높을수록 근로장애인의 월평균 임금액은 줄어드는 음의 상관관계가 있는 것으로 분석되어, 생산활동 보다 상담과 평가 등의 재활훈련과 프로그램에 시간을 많이 투자할수록 생산력이 떨어지는 것으로 분석되었다. 둘째, 개별 직업재활시설 효율성 분석 결과 효율적인 시설이 더 많았으며, 비효율적인 시설의 공통점은 투입요인이 산출요인에 비하여 과잉공급되고 있기 때문인 것으로 나타나, 업재활시설이 보다 효율적으로 운영되기 위한 구체적 방안을 제시하였다. This study was designed to present efficient operational directions and the related tasks for vocational rehabilitation facilities via an analysis of their relative efficiency. In order to achieve the objectives of this study, first it was derived the efficiency factors by analyzing the operational status of the facilities. Then, it was analyzed the co-relationship among the factors and the efficiency of the facilities by using the DEA (Data Envelopment Analysis) method. The study outcome is summarized as follows: First, the input and output variable factors revealed that those facilities that perform more counseling or assessment activities have more rehabilitation programs. The vocational rehabilitation facilities perform their business operations according to a series of vocational rehabilitation service systems. However, it was found that facilities which have more rehabilitation programs pay less monthly average wages to the persons with disabilities, indicating that there exists a negative co-relationship between the two factors. Second, eleven out eighteen DMUs were classified as efficient vocational rehabilitation facilities through analysis of the efficiency of individual facilities. It was revealed that the common causes for their inefficiency were excessive input factors coupled with insufficient output factors. The variable factors that most affect the efficiency of vocational rehabilitation facilities are not their input budget or number of employees but their insufficient efforts and the lack understanding of their efficiency. Therefore, the vocational rehabilitation facilities cannot achieve efficiency simply on the basis of government input or the number of employees. Indeed, they need to strive to enhance their efficiency or output factors with limited input factors. nalysis(DEA)