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한국인 주요우울장애 환자에서 혈중 ACTH, Cortisol 농도와 해밀턴 우울 평가 척도의 신체증상 항목과의 상관관계
여혜빈,김린,함병주,심세훈,권영준,정희연,정한용,한상우,이민수,이화영 대한생물치료정신의학회 2011 생물치료정신의학 Vol.17 No.2
Objectives:Hypothalamic-Pituitary-Adrenocortical(HPA) system dysregulation plays an important role in the pathophysiology of major depressive disorder. Medically unexplained somatic symptoms comprised the predominant complaints of korean patients with major depressive disorder. It might be related to dysregulation of HPA system and somatic symptoms. The aim of this study was to investigate the association between Hamilton Depression Rating Scale severity and the Plasma Adrenocorticotropic Hormone(ACTH) & Serum Cortisol level in Korean patients with major depressive disorder. Methods:Our study design was prospective. A total 111 hospitalized patients with major depressive disorder (DSM-IV) at Anam Hospital, Korea University Medical Center between Jan 2009 and May 2011 were selected. Hamilton Depression Rating Scale was measured by psychiatrist. Plasma ACTH, Serum Cortisol levels were analyzed at the time of admission. Results:There are significant correlations(p<0.05) between Hamilton Depression Rating Scale of somatic component(HAM-D 11-15 item) and Plasma ACTH and Serum Cortisol level. However, other HAM-D sub items were not significantly correlated with Plasma ACTH and Serum Cortisol level except somatic component. Conclusion:Our Study results suggest that hyperactivity of HPA axis might be correlation with somatic symptoms in korean patients with major depressive disorder.
Plyometric Training과 비타민 C 투여가 남고생의 체력, 혈중 젖산, 암모니아 및 젖산탈수소효소에 미치는 영향
장준원,김세종,이현미,서혜림,조현숙,고정림,염종우,예정복,백영호 釜山大學校 附設 體育科學硏究所 2003 體育科學硏究所 論文集 Vol.19 No.-
The purpose of this was to examine the effect of plyometric training and vitamin C ingestion on physical fitness and fatigue substance....
윤혜준 한국외국어대학교 외국문학연구소 2004 외국문학연구 Vol.- No.16
The complex challenge Australian Aborigines raise against the very notion of history is manifold. To begin with, there is the very idea of recorded history, which stands in direct confrontation with the long oral tradition of Aboriginal culture, whose lack of encoded written language had been used by the European settlers as justification of their destructive acts of 'civilizing mission' imposed on them. Against this outmoded ideology, one has to endorse the alternative view of civilization which allows one to appreciate, among others, the ecologically sound lifestyle of the hunter-gathering cultures, which at this very conjuncture of global environmental threat, can even appear to be a civilization superior to that of Western modernity. At the second level, there is the written or glossed history of the Aborigine's heroic struggle against the European invaders, which historians such as Henry Reynolds have successfully incorporated into the very fabric of Australian history. At the most sophisticated level, there is the literary history of the Aborigines writing their lives and histories in the language of the conquerors, in which the works of Mudrooroo, the recent scandal about his ethnic "purity" notwithstanding, with their bold reconstruction of history, stand out as the most significant achievements. In Mudrooroo's works, as much as in his supposedly inauthentic genetic identity itself, the boundaries between fact and fiction, the actual and the virtual, the individual and the collective, purity and hybridity, are all brought under radical scrutiny in such a way that the particular instances of the original Australians gain universality as exemplary symptoms or overdeterminations of this late postmodern world.
이혜승,이재원,한길로,황적준 大韓法醫學會 1998 대한법의학회지 Vol.22 No.2
When we intend to do the personal identification using DNA profiles, it will obviously be better to use as much information as possible. The power of identification is increased by using the genetic marker system such as VNTRs or STRs. Although STRs do not have many alleles per locus as VNTRs, these can be compensated by a large number of loci that are potentially usable. However, it will be more efficient to use a morphic loci. Therefore, prior to choose the genetic marker system of STRs for identification, it is essential to consider the statistical parameters of each STR locus, such as obs-H(observed heterozygosity), exp-H(expected heterozygosity), pM(probability of match), DI(discrimination index), PD(power of discrimination), MEC(mean exclusion chance), MEP(mean exclusion paternity), PIC(polymorphic information content) et al. In this article, we described the exact meaning of statistical parameters for the purpose of identification.
조혜진,이경하,이세준,이광원 大韓齒科保存學會 2002 Restorative Dentistry & Endodontics Vol.27 No.4
Compomer is composed of matrix and filler; matrix is made of the combination of resins and polycarboxylic molecules that are light-cured. and a filler is a glass component which is capable of ion-release. The resin content of compomers produces polymerization shrinkage which can adversely affect marginal adaptation. Pretreatment is a fundamental step which is treated with conditioner or primer in the use of these materials. Microleakage of restorative materials has been investigated mostly by dye penetration method. Dye penetration method was not quantitative and not measured repeatedly. Fluid filtration method. introduced and developed by Pashley's group, has been extensively used for 20 years for research purpose to understand the physiology of dentin, as well as the effects of various restorative treatments on dentin permeability. It permits quantitative, nondestructive measurment of microleakage in a longitudinal manner. The purpose of this study was to evaluate the change the change of dentin permeability according to the process of compomer restoration. In this study, CI Ⅴ cavities were prepared on buccal surface of thirty extracted human molars. The prepared cavities were etched by 37% phosphoric acid. The experimental teeth were randomly divided into three groups. Each group was treated with following materials; Group 1 : Prime & Bond NT/Dyract AP, Group 2: Single Bond/F2000 compomer, Group 3 : Syntac Single Component/Compoglass. The bonding agent and compomer were applied for each group following manufactures information. Dentin permeability of each group was measured at each process by fluid filtration method; Step 1 : preparation(smear layer), Step 2 : etching(smear layer removal), Step 3 : applying the bonding agent, Step 4 : filling the compomer. Dentin permeability was expressed by hydraulic conductance(㎕ min^-1cmH_2O^-1). The data were analysed statistically using One-way ANOVA and Sheffe's method. The results were as follows : 1. Dentin permeability differences between each process were significant except between step 1 and step 2(p<0.01). 2. Dentin permeability after removal of smear layer was highly increased(p<0.01). 3. In most case, decrease of dentin permeability was obtained by applying bonding agent(p<0.01). 4. Dentin permeability differences among the experimental groups were not significant(p>0.05). 5. None of compomers used in this study showed perfect seal at the interface.
비주얼 베이직을 활용한 초등학교 고학년용 통계교육 모형
박동준,강혜진 한국수학교육학회 2000 初等 數學敎育 Vol.4 No.2
제7차 교육과정의 확률과 통계영역의 내용에 맞추어 초등학교 고학년을 위하여 비주얼 베이직으로 프로그램한 통계교육모형을 개발하였다. 10개의 모듈로 구성된 통계교육모형은 초등학생들이 쉽게 사용할 수 있도록 하였고, 모형을 실행시키면 다양한 색깔을 갖는 물체들이 컴퓨터의 화면에 나타나고 마우스의 클릭만으로 동적 기능을 볼 수 있도록 하였다. 통계교육모형의 사용 후 설문조사 결과, 모형의 내용과 특성에 대해 긍정적인 평가가 있었고 초등학생들이 확률과 통계에 높은 흥미와 관심을 나타냈다. 마련된 홈페이지에 모형의 실행파일을 올려놓으면 무료로 다운로드하여 사용할 수 있도록 하였다. Based on the contents of probability and statistics areas in the seventh curriculum, we developed a statistics education model programmed by visual basic for upper grade students of elementary schools. The model that was consisted of ten modules can be easily manipulated by elementary school students. The objects with a variety of colors are presented on P.C. monitor and dynamic functions are performed by clicking a mouse. According to the survey after using the model, students positively evaluated the contents and characteristics and showed great interest in the model. We will upload the execution files of the model on our homepage. One can download and use them free.