Thioridazine에 의한 야뇨증 1례

정성훈,김휘중 대한생물치료정신의학회 1997 생물치료정신의학 Vol.3 No.2

요약대부분의 항정신병약물은 요실금과 야뇨증을 유발한다. 도파민 활동을 억제하거나 차단하는 약물은 요실금이나 야뇨증을 야기하고, 반면에 노아드레날린계 활성을 증가시키는 약물들은 배뇨자제를 촉진한다. 최근에는 요실금과 야뇨증은 기저핵 구조 내에서 카테콜라민 신경전달물질의 균형이 깨어짐으로써 이? 汰岵막? 발생한다는 가설이 제안되었다.항정신병약물에 의한 야뇨증과 요실금은 치료 시작 수시간내에 생기거나 첫 몇주 뒤에 산발성으로 생기는 급성 내지 아급성 반응이다. 소변장애의 정도는 이전의 비뇨생계 병력과는 무관하고 야뇨증 단독에서부터 주간 요실금까지의 범위로 다양하다. 야뇨증이나 요실금은 항정신병약물을 계속 사용함에 따라 점차로 호전되고 약물을 중단하면 사라지는 on-off 패턴을 따른다. 항정신병약물에 의한 요실금과 야뇨증은 항정신병약물을 감량하거나 중단하고 또는 다른 계열의 약물을 선택하고 야간보다는 주간에 투약함으로써 조절될 수 있고, 치료효과가 있다고 보고된 amantadine, benztropine, trihexyphenidyl, oxybutynine, ephedrine desmopressin 등을 사용해볼 수도 있다. 항정신병약물에 의한 야뇨증과 요실금은 환자들이 흔히 보고하지 않고 숨기는 경향이 있기 때문에 임상의들이 적극적인 비뇨생식계 부작용에 대해 관심을 가질 필요가 있으며, 향후 항정신병약물에 의한 비뇨생식계 부작용에 대한 체계적인 연구가 지속되어야 할 것으로 생각된다.The authors reported a case of nocturnal enuresis and/or urinary incontinence following thioridazine treatment. A 40 year old male patient with organic personality disorder developed nocturnal enuretic episodes with daily dose 200mg of thioridazine. As we stopped in a week and restart thioridazien with behavioral interventions, nocturnal enuresis was decreased in the frequency after one week of the maintenance of daily dose 200mg of thioridazine and ceased after a month.The authors reviewed the literatures about antipsychotics related with nocturnal enuresis and/or urinary incontinence, pathophysiological mechanisms, the qualitative features and treatment of antipsychotics-induced nocturnal enuresis.

히스토리 정보를 활용한 사용자 지향의 검색 시스템 설계 및 구현

전병휘,김정희,곽호영 제주대학교 공과대학 첨단기술연구소 2002 尖端技術硏究所論文集 Vol.13 No.1

User oriented search system is proposed and implemented using the information of history. For offering more qualified information to user without the redundant search results and unnecessary information of legacy search system, this system uses user information and generates a keyword and category. Comparing user favorite category with search result of legacy search system through the agent oriented search engine, the result close to the user category is only supplied. At the same time, search result is saved as the history databases according to each category to be used for later search work. As a result, the redundant information of search result was efficiently removed and the information close to the user favorite category was obtained.

다중 문턱전압 CMOS를 이용한 저 전력 캐리 예측 가산기 설계

김동휘,김정범 강원대학교 정보통신연구소 2007 정보통신논문지 Vol.11 No.-

This paper proposes a low-power carry look-ahead adder using multi-threshold voltage CMOS. The designed adder is compared with conventional CMOS adder. The propagation delay time is reduced by using low-threshold voltage transistor in the critical path. Also, the power consumption is reduced by using high-threshold voltage transistor in the shortest path. Comparing with the conventional CMOS circuit, the proposed circuit is achieved to reduce the power consumption by 14.71% and the power-delay-product by 16.11%. This circuit is designed with Samsung 0.35㎛ CMOS process. The validity and effectiveness are verified through the HSPICE simulation.

상악골, 하악골 및 이부의 외과적 동시 이동술

이재휘,이호준,이정근,황병남 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.2

Art and science to determine the treatment objectives, specifically, the desired soft tissue changes are firstly established by using the clinician's “esthetic sense” of the facial beauty and proportion aided to a few cephalometric guidelines. In this sense, the dependence on the clinician's “esthetic eye” by Dr. Bell is more important in analyzing the facial proportion than the satisfaction of rigid cephalometric norms. The purpose of this article was to elucidate the indication for simultaneous surgical repositioning of the maxilla, mandible, and chin, and to describe the clinical cephalometric analysis for orthognathic surgery. Representative 6 case reports were presented and discussed to illustrate the esthetic, orthodontic, and surgical treatment objectives with long-term follow-up.

등방성 이종재료 내의 Ⅴ-노치 균열에 대한 응력강도계수 결정에 관한 연구

조상봉,정휘원,김진광 경남대학교 신소재연구소 1999 論文集 Vol.11 No.-

접합계면 V-노치 균열 문제는 고유치와 고유벡터 문제로 수식화할 수 있다. V-노치 균열첨단에서 응력특이성을 가지는 고유치가 존재한다. 상반일 등고선 적분법(RWCIM)은 고유치와 관련된 고유벡터의 계수를 구하는 한 가지의 방법이다. 상반일 등고선 적분법을 이용하여 접합계면 균열의 응력확대계수를 구하도록 시도하였다. 상반일 등고선 적분법으로 구한 응력확대계수와 경계요소법과 변위외삽법을 이용하여 구한 결과를 비교하였다. An inteiface 17-notched crack problem can be formulated as a eigenvalue problem. there are the eigenvalues which give stress singularities at the V-notched crack tip. The RWCIM is a method of calculating the eigenvector coefficients associated with eigenvalues. Obtaining the stress intensity factors for an interface crack in dissimilar materials was examined by the RWCIM. The results obtained for stress intensity factors using RWCIM were compared with those obtained by using the displacement extrapolation method and the BEM.

한국 정상성인에서 이부의 골격 및 연조직의 상대적 비율에 관한 연구

김수연,이정근,황병남,이재휘 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.2

The esthetics of chin contour is very important in facial deformities, and the quantity of soft tissue overlying the symphysis can be helpful to the correct diagnosis and surgical treatment for optimal facial harmony. The objectives of this study is to measure the different thicknesses of skeletal and soft tissues of chin on lateral cephalometric radiographs, to obtain the mean values of normal Korean adults, and to investigate the relative proportions of skeletal and soft tissues of chin. The results were as follows ; 1. In normal Korean adults, the relative proportions of the distances of soft tissue toward skeletal tissue were 1.5 in B point and 0.95 in Pg, and there were significant difference between male and female in the relative proportion of Pg (p<0.05). The relative proportion of the distances of vertical soft tissue toward horizontal soft tissue of Me was 1.91, and there were not significant difference between male and female. 2. In normal Korean adults, the distances of skeletal and soft tissues of chin showed no correlation, but the distances of vertical and horizontal soft tissues of Me showed high correlation (p<0.01). 3. In normal Korean adults, the correlations among the distances of each skeletal and soft tissues of chin were significantly high in both of male and female (p<0.01). Among the relative proportions of the distances of skeletal and soft tissues, the correlations of the proportions of B point and Mp and the proportions of Mp and Pg were significantly high (p<0.01).

적외선 센서를 이용한 다종가스 계측기 구현

최낙진,류정호,강봉휘,이광우,이덕동 경북대학교 센서기술연구소 1997 센서技術學術大會論文集 Vol.8 No.1

The semiconductor gas sensors with a tin oxide as the raw material have been generally used to detect gases in the principle of electrical conductivity variation. However, it was difficult to design the gas detection system due to the non-selectivity, the non-stability and the influence of temperature, humidity etc. Therefore, it was proposed NDIR(non-dispersive infrared) method using pyroelectric infrared sensor to overcome the disadvantage of the semiconductor gas sensors. This method has been recently used to detect various gases in industrial parts. It has the advantages of selectivity, stability and responsibility. The gases used in this paper were CO_(2)(carbon dioxide) and HC(hydrocarbon) series. The system was designed with the Intel MCU i8097BH microprocessor. Main topics were to remove interference effect for other gases and to minimize influence for ambient circumstance by using the software and the hardware techniques.

규칙파를 이용한 방향 스펙트럼 추정방법

김가현,이승휘,민일규,이정환 慶南專門大學 1999 論文集 Vol.27 No.1

MRI를 이용한 양측성 약관절 내장증의 임상적 평가

황병남,이재휘,이정근 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.1

This is a retrospective study of 31 patients, who were diagnosed as bilateral TMJ internal derangement in consequence of magnetic resonance imaging (MRI) of the temporomandibular joint (TMJ) at Department of Dentistry, Ajou University Hospital, and who were compared clinical findings with radiological findings. The results obtained were as follows. 1. The average of the patients of bilateral TMJ internal derangement was 27.3 years with a range from 12 to 74 years, and 93.6% of the patients were youger than 40 years of age. The male-female ratio was 1 : 6.8, and the females of 20∼29 years were most common in 35.5%. 2. In the patients of bilateral TMJ internal derangement, the patients who complained clinical symptoms bilaterally were 38.7% and the patients who complanined clinical symptoms untilaterally were 61.3%. 3. The most common disc position of bilateral TMJ internal derangement was anterior disc displacement without reduction on both sides in 38.7%. The most common disc configuration of bilateral TMJ internal derangement was biconcave on both sides and amorphous on both sides in closed mouth, and was amorphous on both sides in open mouth. 4. In the patients of bilateral TMJ internal derangement, the joints which really showed clinical symptoms were most common in anterior displacement without reduction of 48.9%.

자동차차체 및 부품제조업 산업장의 작업환경실태에 관한 조사 연구

서준호,문덕환,김정호,이채관,황용식,손병철,김대환,이창희,김휘동,이채언 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

Objectives: For the purpose of preparing the fundamental data and control the working environment and assessing the status of working environmental in manufacturing industry of bodies for motor car and of parts. Methods and Materials: Accessories for motor car and its engines the auther measured the noise level, concentration of dust, heavymetals, organic solvents, chemicals to 99 industries(24 working processes) form Feb. 2000 to Oec. 2000. Results: The results were as follows : 1. Mean noise level cutting, grinding, pressing, foundries and shot-blast was exceeded to threshold limit value(TLV) of noise. 2. Mean concentration of total dust was not exceeded to TLV. 3. Mean concentration of Mn in welding process and Pb in drying, welding, fabricating, rolling was exceeded to TLV. 4. Mean concentration for chemicals and organic solvents were not exceeded to TLV. 5. Mean concentration of dust and heavymetals were statistical significant difference between with local ventilation system and without local ventilation system. Conclusion: Above results, author suggest to prepare more passively control to working environment where exceeded the TLV.