Case Reports : Basal Cell Carcinoma on the Pubic Area: Report of a Case and Review of 19 Korean Cases of BCC from Non-sun-exposed Areas

( Jin Park ),( Yong Sun Cho ),( Ki Hun Song ),( Jong Sun Lee ),( Seok Kweon Yun ),( Han Uk Kim ) 대한피부과학회 2011 Annals of Dermatology Vol.23 No.3

Basal cell carcinoma (BCC) is one of the most commonly diagnosed malignant skin tumors and develops characteristically on sun-exposed areas, such as the head and neck. Ultraviolet light exposure is an important etiologic factor in BCCs, and BCCs arising from non-sun- exposed areas are, therefore, very rare. In particular, the axilla, nipple, the genital and perianal areas are not likely to be exposed to ultraviolet light; thus, if BCC develops in these areas, other predisposing factors should be considered. Herein, we report a case of BCC arising on the pubic area in a 70-year-old man. We also performed a survey of the literature and discussed the 19 cases of BCC from non-sun-exposed areas reported to date in Korea.

The Efficacy and Safety of 4-n-butylresorcinol 0.1% Cream for the Treatment of Melasma: A Randomized Controlled Split-face Trial

( Sun Young Huh ),( Jung Won Shin ),( Jung Im Na ),( Chang Hun Huh ),( Sang Woong Youn ),( Kyoung Chan Park ) 대한피부과학회 2010 Annals of Dermatology Vol.22 No.1

Background: Melasma is a common acquired symmetrical hypermelanosis that occurs on sun-exposed areas, and it is frequently observed among women. Various treatment modalities have been tried, but none are completely satisfactory. 4-n-butylresorcinol, which is a resorcinol derivative that has an inhibitory effect on both tyrosinase and tyrosinase-related protein-1, was introduced in 1995 and it has received increasing attention as a new hypopigmenting agent. However, the hypopigmenting effect of 4-n-butylresorcinol in human subjects has only been shown in a few studies. Objective: The aim of this study was to investigate the hypopigmenting efficacy and safety of 4-n-butylresorcinol 0.1% cream for the treatment of melasma. Methods: Twenty patients with melasma were enrolled to this randomized, double-blind, vehicle-controlled, split-face comparative study. The patients were instructed to apply 4-n-butylresorcinol 0.1% cream or vehicle to each side of the face twice daily for 8 weeks. Mexameter measurements were performed along with photography at baseline, 4 weeks and 8 weeks. Adverse events were observed and recorded throughout the study. Results: All the patients completed the study. Mexameter measurements demonstrated that the melanin index of the treated side showed a significant decrease when compared with that of the vehicle-treated side after 4 weeks (p=0.006) and after 8 weeks (p<0.0005). All the adverse reactions were mild and transient. Conclusion: 4-n-butylresorcinol 0.1% cream showed rapid efficacy and it was well tolerated when used for the treatment of melasma. (Ann Dermatol 22(1) 21∼25, 2010)

A rare case of abdominal adenoid basal cell carcinoma in a patient with a history of radiation therapy

Kim, Ji Hun,Kim, Sun Eung,Cheon, Young Woo Korean Society of Plastic and Reconstructive Surge 2020 Archives of Plastic Surgery Vol.47 No.1

Basal cell carcinoma (BCC) is the most common skin cancer and its incidence is steadily increasing. Prior radiation therapy is one of the most important risk factors for BCC. Although the mechanism remains undefined, long-term studies have shown that people exposed to radiation have an increased risk of BCC. Despite the fact that BCC occurs most frequently in sun-exposed areas of the body, patients with a history of radiation therapy have an increased risk of BCC in areas previously exposed to radiation. Here, we report a case of adenoid BCC on the abdomen in a 67-year-old woman after radiation therapy post-hysterectomy.

Geosynchronous Magnetic Field Response to Solar Wind Dynamic Pressure

Park, Jong-Sun,Kim, Khan-Hyuk,Lee, Dong-Hun,Lee, En-Sang,Jin, Ho 한국우주과학회 2011 Journal of Astronomy and Space Sciences Vol.28 No.1

The present study examines the morning-afternoon asymmetry of the geosynchronous magnetic field strength on the dayside (magnetic local time [MLT] = 06:00~18:00) using observations by the Geostationary Operational Environmental Satellites (GOES) over a period of 9 years from February 1998 to January 2007. During geomagnetically quiet time (Kp < 3), we observed that a peak of the magnetic field strength is skewed toward the earlier local times (11:07~11:37 MLT) with respect to local noon and that the geosynchronous field strength is larger in the morning sector than in the afternoon sector. That is, there is the morning-afternoon asymmetry of the geosynchronous magnetic field strength. Using solar wind data, it is confirmed that the morning-afternoon asymmetry is not associated with the aberration effect due to the orbital motion of the Earth about the Sun. We found that the peak location of the magnetic field strength is shifted toward the earlier local times as the ratio of the magnetic field strength at MLT = 18 (B-dusk) to the magnetic field strength at MLT = 06 (B-dawn) is decreasing. It is also found that the dawn-dusk magnetic field median ratio, B-dusk/B-dawn, is decreasing as the solar wind dynamic pressure is increasing. The morning-afternoon asymmetry of the magnetic field strength appears in Tsyganenko geomagnetic field model (TS-04 model) when the partial ring current is included in TS- 04 model. Unlike our observations, however, TS-04 model shows that the peak location of the magnetic field strength is shifted toward local noon as the solar wind dynamic pressure grows in magnitude. This may be due to that the symmetric magnetic field associated with the magnetopause current, strongly affected by the solar wind dynamic pressure, increases. However, the partial ring current is not affected as much as the magnetopause current by the solar wind dynamic pressure in TS-04 model. Thus, our observations suggest that the contribution of the partial ring current at geosynchronous orbit is much larger than that expected from TS-04 model as the solar wind dynamic pressure increases.

백서에서 Depulpin®과 Formocresol에 대한 치수와 치근단 조직의 반응

문형인,김선호,황윤찬,오병주,황인남,김선헌,정선와,윤창,오원만 大韓齒科保存學會 2002 Restorative Dentistry & Endodontics Vol.27 No.4

One fifth dilution of formocresol is usually for pulpotomy of the primary teeth and emergency pulpotomy of the permanent teeth. However, the use of formaldehyde has been subjected to criticism because it may be absorbed into the blood stream and become distributed systemically, it may also alter the pulp tissue rendering it immumologically active, and have carcinogenic potential. Recently Depulpin®(VoCo., Germany) gains popularity as a devitalizing agent during root canal therapy in spite of high concentration of 49% paraformaldehyde because it facilitate devitalization of pulp and make root canal therapy easier. But there have been not enough publications about the reaction of pulp and periapical tissue caused by Depulpin. This study was performed to evaluate the histological changes in pulp and periapical tissue of rats after pulpotomy using formocresol and Depulpin and to elucidate the toxic effects of these agents. Thirty six Sprague-Dawley rats were anesthetized by intraperitoneal injection of ketamine. Maxillary first molar teeth were used for pulpotomy with formocresol and Depulpin. Rats were sacrificed after 2 days, 4 days, 1 week, 2 weeks, 3 weeks and 4 weeks respectively. Specimens were histologically observed by light microscope changes in pulp and periapical tissue. The obtained results were as follows. 1. Formocresol group A zone of fixed tissue, in which odontoblasts could clearly be defined, was present directly underneath the pulpotomy dressing in almost all teeth of this group. This was followed by an area of necrotic tissue which resembled dried out fibrous tissue with no cellular detail except some pyknotic nuclei. In the specimens of after 2 days, 4 days, 1 week, 2 weeks in which vital tissue was present. it was separated from the fibrous area by a zone of inflammation. In the specimens of after 3 weeks and after 4 weeks, inflammatory infiltrate was in the periodontal ligament adjacent to the apical foramina of the teeth. 2. Depulpin® group The area of necrotic tissue which had no cells and fibers , was present adjacent to the dressing. This was followed by dried out fibrous tissue with no cellular details except some pyknotic nucleli. A short stump of vital pulp with odontoblasts was present at the end of the canal after 2 days. Inflammatory infiltrate was in the periodontal ligament after 4 days and after 1week. Severe root resorption and necrosis of periapical tissue opposite the root resorption site were defined after 2 weeks and after 3 weeks. Periapical lesion which consist of necrotic tissue surrounded by a fibrous connective wall. was found after 4 weeks. The results indicated that Depulpin can cause more adverse reaction to the dental pulp and periapical tissue than formocresol, and further studies are needed for its clinical use with safety.

부비동 내시경수술 후 비음도 변화

동헌종,김선일,권중근,윤영선,강수미,추광철 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.7

장기 이식 환자에 있어서의 부비동염의 치료

동헌종,류준선 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.2

한국의 두부 연혁과 신규 두부의 개발

손헌수 漢陽大學校 民族學硏究所 1997 民族과文化 Vol.6 No.-

선택적 치료 교육 활동의 실행 방안

전현선 大邱大學校 特殊敎育·再活科學硏究所 2000 特殊敎育硏究 Vol.23 No.1

본 연구는 선택적 치료 교육 활동의 실행 방안을 모색하기 위하여 학생 중심, 수요자 중심, 수행 능력 중심의 치료 교육 활동의 구성 체제, 전개 방안, 그리고 운영 방안을 알아보는데 목적이 있었다. 연구의 결과와 논의를 토대로 내린 결론은 다음과 같다. 첫째, 학생 중심의 치료 교육 활동은 이들의 독특한 교육적 욕구를 충족시켜 주는 가장 적절한 수업을 보장하는 교육 체제이어야 한다. 둘째, 수요자 중심의 선택적 치료 교육 활동을 전개하기 위해서는 개별화 교육 계획, 개별화수업 계획이 수립되어 수요자의 선택이 보장되는 교육 체제이어야 한다. 셋째, 수행 능력 중심의 선택적 치료 교육 활동은 개인 학생의 능력을 토대로 계속적인 성공감이 보장되는 교육 체재이어야 한다. Therapeutic educational service is activity promoting education for the whole man, maintainenance of unlimited life, recovery of physiological self-control function, supplement of disability and recovery of life skills. The purpose of this study was to investigate execution plan of selected therapeutic educational service for the student with disabilities. The results of this study were as follows ; First, therapeutic educational service of student centered were promoting education for the whole man and appropriate subject lesson activity and special activity to students with' unique educational needs' in order to practice an idea. Second, therapeutic educational service of consumer centered should be performed selectively according to individual character of student with disability. Finally, therapeutic educational service of competence centered should be able to perform competence centered selected therapeutic educational service according to feature and degree of severity. Therefore, Therapeutic educational service was education activity. Teacher should practice it through play, exercise, and occupation according to character of student, and carry out instruction slowly, safely, and naturally.

구조적 가족치료의 임사사례 적용에 관한 연구

김효순,김헌수,박인호,민병근 中央醫學社 1989 中央醫學 Vol.54 No.8

Today, through the rapid industrialization and civilization of Korean society, the Korean family structure has been shifting from extended family structure of the past to nuclear family structure. This changing trend has had great effects on family structure and health of family members in aspects of body and mind. Family therapy has shown a rapid development in the developed countries since 1950 and there has been 5 important theories; the psychoanalytic family therapy theory of Nathan Ackerman, Bowen's family system theory, the communication theory of Satir, Minuchin's structural family therapy, and Haley's strategic family therapy theory. This study proposes the solution of fundamental problem of family member's mental health caused by unbalance of family structure. Minuchin's theory recognized of its practical appropriateness and popular usage, was selected and applied to hospitalized mental patients to verify its applicability in Korean family structure. After the comprehensive review of Minuchin's family therapy, the case analyses approach through the Minuchin's structural family therapy is applied. The' subjects of this study consist of, randomly selected, five families of psychiatric patients in university medical center who do not have hereditary diseases. The conclusions from this study are as follows: First, Family and patient with motivation for therapy have shorter remedy period and few frequency of family therapy than family and patient without it. Second, in Korean society having patriarch system, the father has more influence on children than the mother. Therefore, the more father takes up a positive attitude, the more Minuchin's theory is effective. Third, in usual family structure, the family therapy is more effective, on the other hand, the defected family that undergo divorce or separation is less effective. Fourth, the technique of reframing, joining, reality challenging, tasks were very effective. Finally, in proportion to individual and sociodemographic variables, as parent's educational level, economical level, etc., the therapy effects are different. In conclusion, this study verify that the Minuchin's family therapy model is appropriate in adapting to practically clinical cases. The further study is to develop family therapy model that is suitable to various flexible family structures.