UV 광산화 공정 및 광촉매 공정을 이용한 벤젠 및 톨루엔 가스의 처리

황철원,전보경,김찬훈,서정민,최금찬 동아대학교 환경문제연구소 2003 硏究報告 Vol.25 No.2

Volatile organic compounds (VOCs) are widely used in both industrial and domestic activities. This extensive use results in adverse effect in aquatic, soil and atmospheric environments. Conventional methods for treating VOCs from gas streams, such as absorption, adsorption, condensation and thermal /catalytic incineration all have their inherent limitations and none are definitely cost-effective to treat emissions from the small workplace such as architectural coating, printing, and dry cleaning. In this study, photooxidation-photocatalytic oxidation process was applied in the decomposition of VOCs and benzene and toluene, typical VOCs in industrial area, which were adapted as experimental gases. In photooxidation process, the decomposition efficiency of benzene and toluene was evaluated by varying different conditions, such as UV output, flowrate and background gas. The results showed that the decomposition efficiency of benzene and toluene increased considerably with increasing UV output and retention time. In case of background gas, the decomposition efficiency in standard air was higher than that in nitrogen. In photooxidation-photocatalytic oxidation process, the decomposition efficiency was higher than that in photooxidation process and the concentration of ozone generated from photooxidation reactor was drastically decreased after photocatalytic oxidation process. From this study, the results indicate that photooxidation-photocatalytic oxidation process is ideal for treatment of benzene and toluene from the small workplace. But further process optimization must be achieved to apply this process in workplace.

응급실에서 시행된 기관내 삽관의 현황

김병철,강보승,송형곤,이정훈,송근정,정연권 대한응급의학회 1999 대한응급의학회지 Vol.10 No.4

Background : The purpose of this study was to analyze the endotracheal intubation cases performed in the emergency department. Methods : We investigated retrospectively 326 cases of endotracheal intubation performed in the emergency department of a tertiary care center form April 1, 1998 to March 31, 1999. We focused on operators, medications used, its success rate and immediate complications, and the relationship between its success rate and medications. Results : Of 326 consecutive intubations, 193 patients(59.2%) were done by emergency medicine residents or attending physician. While 320 patients(98.2%) were successfully intubated, 6 patients could not be intubated and 2 patients underwent tracheostomy. Of 50 cases of intubations(15.3%) attempted with paralyzing agents, 48 cases were done with succinylcholine and 46 cases underwent by emergency physicians. Intubations with neuromuscular paralysis resulted in high success rates at the first attempt. Of 55 immediate adverse events were encountered in 47 patients(desaturation=17, bronchial intubation=15, hypotension=8, bradycardia=4, cardiac arrest=2, others=5). Conclusion : At this institution, paralyzing agents were used infrequently, but almost all of them were used by emergency physicians.

부산지역 산성강우의 장기적인 화학적 성상의 변화

황성욱,전보경,김찬훈,서정민,최금찬 동아대학교 환경문제연구소 2001 硏究報告 Vol.24 No.1

It is important to know the impacts of acid rain because of soil acidification, reduced biological productivity. Many researchers were interested in regional acid problems, and former research were focued in short-term trends of acid rain. It is not easy to evaluate acid rain problems because of many parameters relating to meteorological factors, which are wind, temperature, humidity and other factors. Rainfall sampling for this study was done from September 1933 to December 2000 in Dong-A University, Busan. All Samples were collected in separately to early fraction and succeeding fraction. Also, the samples were measured for pH, and EC, cations and anions were analysed by ion Chromatography.

알코올 사용 장애 환자에서 알코올 사용의 심각도에 따른 불안 및 우울 증상과의 연관성

천은진,이준엽,구본훈,문보영,정진영,정성훈 대한생물치료정신의학회 2011 생물치료정신의학 Vol.17 No.2

Objectives:The purpose of this study was to examine the relationships of anxiety& depressive symptoms according to the severity of alcohol use in patients with alcohol use disorder. Methods:A total of 85 patients with alcohol use disorders were enrolled in this study. The severity of alcohol use was measured by the Korean version of alcohol use disorders identification test(AUDIT-K)& National Alcohol Screening test(NAST). Anxiety and depressive symptoms were measured by using the Beck Anxiety Inventory(BAI) and the Beck Depression Inventory(BDI), respectively. Pearson’s correlation test was applied to correlate among the severity of alcohol use, anxiety and depressive symptoms. Results:The mean scores of AUDIT-K, NAST, BAI and BDI were 22.22(±8.28), 6.24(±3.25), 18.64(±13.08), and 22.05(±10.13), respectively. Pearson’s correlation test showed that between the score of AUDIT-K and NAST, BAI or BDI, there were positively significant correlations(r=.534, p<.01 r=.231, p<.05 r=.334, p<.01), respectively. And in cases of≥26 score of AUDIT-K, there were much more positive correlations with BAI(r=.425, p<.05). Conclusion:The results of this study demonstrated that patients with alcohol use disorders have high co-morbid anxiety and depressive disorders. Overall, the greater severity of alcohol use may be associated with more anxiety and depressive symptoms. However, it is suggested that in the patients with severe alcohol use, correlation appeared to be positive only for anxiety symptoms.

베체트병 환자에서 Azathioprine으로 유발된 급성 췌장염 1례

김기향,권민정,김동기,김애란,김윤정,박지훈,이영태,박보민,김동욱 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Although many drug are thought capable of initiating acute pancreatitis, following azathioprine administration represents the 5% incidence by far the highest recorded incidence to date. We report a 35-year-old male who developed acute pancreatitis in the course of treatment with azathioprine for Behcet's disease. He was admitted due to abdominal pain, diarrhea, and fever for 10 days. Serum amylase and lipase levels were 510U/L and 3702U/L respectively. The abdominal CT scan revealed diffuse enlargement of the pancreas. There was no history of alcohol use or gall bladder disease. We considered drugs, especially azathioprine, as the cause of acute pancreatitis. We diagnosed it as acute pancreatitis. The patient was treated conservatively with hydration and analgesics. The symptom subsided within four days. Five days later, azathioprine was resumed. And the patient complained of abdominal pain. The elevated levels of serum amylase and lipase confirmed the recurrence of pancreatitis. His symptom subsided when azathioprine intake the stopped, and the serum amylase and lipase levels returned to normal level within five days.

젊은 성인에서 흡연에 의한 상완동맥 내피기능의 부전에 관한 연구

이상철,권영주,방덕원,이선해,이보영,김지욱,김영훈,온영근,현민수,김성구 순천향의학연구소 2002 Journal of Soonchunhyang Medical Science Vol.8 No.1

Background and Objectives : Cigarette smoking is a major factor and the most modifiable risk factor for atherosclerosis. Endothelial dysfunction is an early event in atherosclerosis, before the structural change of the systemic arteries. We hypothesized that endothelial dysfunction might be present in the systemic arteries of young adult smokers and that this might be dose-dependent phenomenon. Therefore, we try to certify that smoking is associated with endothelial dysfunction in healthy young adults without other risk factor of atherosclerosis. Subjects and Methods : we studied noninvasively 29 subjects aged 3 to 4 decades without other risk factor of atherosclerosis, they were composed of the two groups, current smokers(n=15) and nonsmokers(n=14). Smoking history varied from 3 to 20 pack years. Using high-resolution ultrasound, vessel diameter and mean flow rate were measured at rest, during reactive hyperemia(with flow-mediated endothelium-dependent dilation), and after sublingual nitroglycerin(NG-induced endothelium-independent vasodilation). Result : Flow mediated endothelium dependent dilation was observed in the control subjects (9.4±3.44%) but was impaired in the smokers(5.8±2.51%)(p=0.004). NG-induced endothelium independent dilation is no difference in all subjects. Conclusion : Cigarette smoking is associated with endothelial dysfunction in healthy young adults.

당뇨병 백서의 대동맥에서 열 자극이 혈관 운동성에 미치는 영향

구성모,이순희,한정훈,정기영,김인겸,김정국,하승우,김보완 대한당뇨병학회 2002 Diabetes and Metabolism Journal Vol.25 No.5

연구배경:열자극은 열자극 단백질의 생성을 유도하여 유해한 자극에 대한 세포내 반응을 유도하는 것으로 알려져 있다. 열자극 단백질은 여러 조직에서 발현되며 일부 열자극 단백질은 산화 스트레스에 대해 세포를 보호하는 기능을 나타내기도 한다. 최근 보고에 의하면, 일부 열자극 단백질은 혈관운동성과 관련이 있다고 한다. 당뇨병은 수축물질에 대한 과다한 수축과 이완물질에 대한 이완능의 저하를 특징으로 하는 혈관 운동성의 장애를 초래하는 대표적인 질환이다. 이런 혈관운동성의 장애는 당뇨병성 혈관병증의 병인에 중요한 요소이다. 그러나 고혈당의 조건에서 혈관 운동성에 대한 열자극의 효과에 대해서는 잘 알려져 있지 않으며 그 기전에 대해서도 밝혀진 것이 없다. 이에 스트렙토조토신으로 당뇨병을 유발한 백서 대동맥에서 열자극이 혈과운동성에 미치는 영향에 대하여 연구하였다. 방법:당뇨병 백서 대동맥을 적출하여 대동맥환을 준비하고 장치한 후 42도에서 45분간 열자극을 가한군과 열자극을 가하지 않은 군사이의 혈관 수축물질에 대한 수축반응과 이와물질에 대한 이완반응을 측정하였다. 혈관반응을 측정한 후 대동맥환을 얼리고 열자극단백질 HSP 70의 발현을 조사하였다. 결과:당뇨병 백서와 정상 대조군 백서의 대동맥에서 KCI과 phenyephrine에 대한 혈관 수축반등은 열자극을 준 군에서 주지 않은 군에 비해 현저하게 증가하였다. 열자극은 당뇨병과 정상 대조군의 대동맥에서 혈관수축반응의 증가 뿐만 아니라 HSP 70의 발현을 의미있게 증가시켰다. 정상 대조군의 대동맥에서 아세틸콜린에 대한 이완반응은 열자극을 준 군과 주지 않은 군사이에 통계학적 유의한 차이는 없었다. 반면에 당뇨병 백서의 대동맥에서는 열자극을 준 군이 주지않은 군에 비해 아세틸콜린에 대한 이완반응이 유의하게 감소하였다. 결론:이상의 결과는 당뇨병과 정상쥐에서 열자극에 대한 혈관 수축반응의 증가는 HSP 70의 발현을 유도하여 일어날 수 있음을 시사하여 당뇨병군에서 정상 대조군에 비해 열자극에 대한 이완반응이 감소하는 기전은 많은 연구가 되어야 할 것으로 생각된다. Background: Heat shock has been known to change cellular response to noxious stimuli by inducing heat shock proteins(HSP). HSP are expressed in many tissues, and increased expression of some HSP enhances the survival of cells exposed to oxidative stress. Recently, Some HSP are known to associate with vascular reactivity. Under diabetic conditions, there is a abnormal vascular reactivity to relaxing or contracting factors. Abnormal vascular response to some stimuli is an important role in the development of diabetic complications. However, the effects of heat shock on the vascular reactivity in diabetic condition is unclear. Therefore, we investigated effects of heat shock on the vascular reactivity in isolated aorta of streptozotocin-induced diabetic rats. Methods: After mounced in organ bath, aortic ring preparations were exposed to 42℃ for 45 minutes followed by being subjected to contraction and relaxation in 4 hours. Tissues were frozen for measurement of HSP 70 and phosphorylation of myosin light chain after functional study. Results: Heat shock not only increased expression of HSP70 in rat aorta but also augmented contraction to KCI and phenylephrine in the aorta of control and diabetic rats(p<0.05). Relaxation responses to acetylcholine (Ach) were not changed in the aorta of control rats with and without heat shock for 45 minutes. However, heat shock for 45 minutes decreased relaxative responses to Ach in the aorta of diabetic rats compared to those in the aorta of control rats. Conclusion: This result suggests that heat shock increases vascular contractility in the aorta of diabetic and control rats through the induction of HSP70 while heat shock seems to decrease relaxative response in the aorta of diabetic rats compared to control rats(p<0.05). Whether heat shock impaired relaxative response in the aorta of diabetic rats deserves additional studies (J Kor Diabetes Asso 25:343~353, 2001).

A survey of patients’ perspectives of steroid injection (ppyeojusa) in Korea

Bo-Mi Shin,홍성준,Yun Hee Lim,Jae Hun Jeong,Ho Sik Moon,Hey Ran Choi,Sun Kyung Park,Richard Jin Woo Han,Jae Hun Kim 대한통증학회 2019 The Korean Journal of Pain Vol.32 No.3

Background: Steroid injections are commonly used in pain clinics to relieve pain and treat inflammation. In Korea, these steroid injections are well known as ‘ppyeojusa’, which means to inject into the bone in Korean. Some patients often have a negative perception of this treatment method due to inaccurate information about the treatment and side effects of steroids. The purpose of this study is to investigate patients’ perception and knowledge of ppyeojusa.Methods: A questionnaire about ppyeojusa was completed by patients who visited one of the pain clinics in nine university hospitals, from August 1 to September 10, 2017.Results: Three-hundred seventy-four patients completed the survey. Eighty-five percent of patients had had ppyeojusa, and 74% of the respondents had heard of ppyeojusa from the mass media, friends or relatives. Only 39% of the patients answered that this injection was safe without side effects if properly spaced. Of the patients surveyed, 21% responded that ppyeojusa are “injections into the bone”; while 15% responded that ppyeojusa are “terrible injections that melted ‘the bone if used a lot’”. Half of the patients did not know what the active constituent is in ppyeojusa. If steroid injections are advised by the pain specialists, 89% of the patients would consent.Conclusions: Most pain clinic patients have heard of ppyeojusa. Most patients obtained information about ppyeojusa from mass media, rather than their physicians. Therefore, it is likely that most patients have inaccurate knowledge.

Poster Session : PS 1619 ; Miscellaneous : Prevalence of Chest X-Ray Abnormalities by Amount of Smoking in the General Population

( Bo Ram Lee ),( Yu Il Kim ),( Chul Min Ahn ),( Ji Ye Jung ),( Ju Ock Kim ),( Jin Young An ),( Hyoung Kyu Yoon ),( Sang Haak Lee ),( Yeong Hun Choe ),( Chang Hoon Han ),( Joo Hun Park ),( Jae Yeol Kim 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: A simple chest x-ray (CXR) is commonly used to examine the chest and lung disease. There are few reports on the prevalence of CXR abnormalities in the general population. We aimed to investigate the prevalence of abnormalities seen on CXR in the general population and risk factors including smoking associated with these abnormalities. Methods: We analyzed the data of the 4th and 5th Korea National Health and Nutrition Examination Survey; a cross-sectional survey in the general population of Korea. A total of 27,936 subjects aged 19 years or more were enrolled in this study. CXR fi ndings were categorized into 5 groups; normal, tuberculosis (active or inactive), lung nodule or cancer or mediastinal disease, active other lung diseases, inactive other lung diseases. The amount of smoking was classifi ed as never, =15 pack-years, and >15 pack-years. Results: The prevalence of CXR abnormalities was 12.8 % (n=3180); 9.5% in never- smokers, 9.9% in smokers who had smoked =15 pack-years, 19.1% in smokers who had smoked >15 pack-years. The most common abnormal fi nding was pulmonary tuberculosis. Signifi cant independent risk factors for CXR abnormalities by multivariate analysis were age (40-59 years: odds ratio [OR], 3.40; 95% confi dence interval [CI], 2.93 - 3.93; = 60 years: OR, 9.81; 95% CI, 8.52 - 11.29), sex (male) (OR, 1.68; 95% CI, 1.50 - 1.88) and smoking amount (>15 pack-years) (OR, 1.19; 95% CI, 1.05 - 1.35). Conclusions: Abnormalities on CXR were more prevalent in moderate to heavy smokers, older subjects and men in the general population. The prevalence increased with increased amount of smoking. Since cigarette smoking is a preventable risk factor for lung disease, efforts are needed for smoking cessation in the community.

Thematic Poster : TP-79 ; Prevalence of Chest X-Ray Abnormalities by Amount of Smoking in the General Population

( Bo Ram Lee ),( Yu Il Kim ),( Chul Min Ahn ),( Ji Ye Jung ),( Ju Ock Kim ),( Jin Young An ),( Hyoung Kyu Yoon ),( Sang Haak Lee ),( Yeong Hun Choe ),( Chang Hoon Han ),( Joo Hun Park ),( Jae Yeol Kim 대한결핵 및 호흡기학회 2014 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.118 No.-

Background: A simple chest x-ray (CXR) is commonly used to examine the chest and lung disease. There are few reports on the prevalence of CXR abnormalities in the general population. We aimed to investigate the prevalence of abnormalities seen on CXR in the general population and risk factors including smoking associated with these abnormalities. Methods: We analyzed the data of the 4th and 5th Korea National Health and Nutrition Examination Survey; a cross-sectional survey in the general population of Korea. A total of 27,936 subjects aged 19 years or more were enrolled in this study. CXR findings were categorized into 5 groups; normal, tuberculosis (active or inactive), lung nodule or cancer or mediastinal disease, active other lung diseases, inactive other lung diseases. The amount of smoking was classified as never, =15 pack-years, and >15 pack-years. Results: The prevalence of CXR abnormalities was 12.8 % (n=3180); 9.5% in never-smokers, 9.9% in smokers who had smoked =15 pack-years, 19.1% in smokers who had smoked >15 pack-years. The most common abnormal finding was pulmonary tuberculosis. Significant independent risk factors for CXR abnormalities by multivariate analysis were age (40-59 years: odds ratio [OR], 3.40; 95% confidence interval [CI], 2.93 - 3.93; = 60 years: OR, 9.81; 95% CI, 8.52 - 11.29), sex (male) (OR, 1.68; 95% CI, 1.50 - 1.88) and smoking amount (>15 pack-years) (OR, 1.19; 95% CI, 1.05 - 1.35). Conclusions: Abnormalities on CXR were more prevalent in moderate to heavy smokers, older subjects and men in the general population. The prevalence increased with increased amount of smoking. Since cigarette smoking is a preventable risk factor for lung disease, efforts are needed for smoking cessation in the community.