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Developing a Solution to Improve Road Safety Using Multiple Deep Learning Techniques
Humberto Villalta,Min gi Lee,Yoon Hee Jo,Kwang Sik Kim 한국인터넷방송통신학회 2023 International Journal of Internet, Broadcasting an Vol.15 No.1
The number of traffic accidents caused by wet or icy road surface conditions is on the rise every year. Car crashes in such bad road conditions can increase fatalities and serious injuries. Historical data (from the year 2016 to the year 2020) on weather-related traffic accidents show that the fatality rates are fairly high in Korea. This requires accurate prediction and identification of hazardous road conditions. In this study, a forecasting model is developed to predict the chances of traffic accidents that can occur on roads affected by weather and road surface conditions. Multiple deep learning algorithms taking into account AlexNet and 2D-CNN are employed. Data on orthophoto images, automatic weather systems, automated synoptic observing systems, and road surfaces are used for training and testing purposes. The orthophotos images are pre-processed before using them as input data for the modeling process. The procedure involves image segmentation techniques as well as the Z-Curve index. Results indicate that there is an acceptable performance of prediction such as 65% for dry, 46% for moist, and 33% for wet road conditions. The overall accuracy of the model is 53%. The findings of the study may contribute to developing comprehensive measures for enhancing road safety.
Humberto Cortes-López,Javier Castro-Rosas,Rodolfo García-Contreras,José Salud Rodríguez-Zavala,Bertha González-Pedrajo,Miguel Díaz-Guerrero,Javier Hernández-Morales,Naybi Muñoz-Cazares,Marcos Soto-Her 한국식품영양과학회 2021 Journal of medicinal food Vol.24 No.9
Hibiscus sabdariffa L. (Hs) calyxes, rich in organic acids, are included in diets in different countries. In recent years, some phytochemicals have been shown to reduce bacterial virulence at sublethal concentrations by interfering with quorum sensing (QS) systems. Therefore, in this study the antivirulence properties of Hs calyxes and two γ-lactones (hibiscus acid [HA] and its methyl ester) in Pseudomonas aeruginosa were analyzed. Acetone and methanol extracts of Hs showed anti-QS activity by inhibiting violacein production (60% to 80% with 250 μg/mL). In molecular docking analysis, the γ-lactones registered a good binding score, which suggests strong interaction with the active site of LasR protein. To verify their effect in vitro, they were isolated from Hs and evaluated in six QS-regulated phenotypes, as well as in ExoU toxin that is released by the type III secretion system (T3SS). At 500 μg/mL they reduced alkaline protease (29–52%) and elastase (15–37%) activity, biofilm formation (∼75%), and swarming (50%), but there was no effect on pyocyanin production, hemolytic activity, or type III secretion. In a mouse abscess/necrosis model, HA at sublethal concentrations (15 and 31.2 μg/mL) affected infection establishment and prevented damage and systemic spread. In conclusion, HA is the first molecule identified with antivirulence properties in Hs with the potential to prevent infections caused by P. aeruginosa.
Humberto R. Gamba,Marcos V. H. Rambo,Gustavo B. Borba,Joaquim M. Maia,Carlos A. S. Ramos 대한의용생체공학회 2013 Biomedical Engineering Letters (BMEL) Vol.3 No.3
Purpose Electronic foramen locators are widely used to locate the apical foramen (AF), by measuring the electrical impedance between the electrodes (ZE). There is no in vivo study that completely characterizes ZE as a function of frequency and endodontic file tip position. The results of in vivo studies of the impedance ZE and a coefficient that can be used to locate the AF are presented. Methods An electronic device was specially built to study ZE. Ten root canals were used in the experiment. The spectral attenuation of ZE was in vivo measured with the endodontic file tip placed at -3.0, -2.5, -2.0, -1.5, -1.0, -0.5 and zero millimeters from the root canal AF. At each file position the spectrum attenuation was modeled. Based on the attenuation models an endodontic spectral attenuation coefficient (ESAC)was defined. Results The in vivo results demonstrate that the spectral attenuation of the electrical impedance ZE has an exponential decay in the frequency range of the study. It was verified that ESAC can be correlated to the distance between the endodontic file tip and the apical foramen. The ESAC accuracy was assessed and the results showed that it can locate the AF with accuracy better than 0.5mm. Conclusions The spectral attenuation of ZE has an exponential decay for all file tip distances from the AF. It supports the feasibility of ESAC to accurately locate the root canal AF. Moreover, using frequencies steps of one octave makes the implementation of ESAC in an embedded system easier.
Humberto J. Morris,Olimpia V. Carrillo,Marı´a E. Alonso,Rosa C. Bermu´dez,A´ ngel Almarales,Gabriel Llaurado,Yamila Lebeque,Roberto Fontaine 한국식품영양과학회 2011 Journal of medicinal food Vol.14 No.12
This study examined the effects of oral administration of an enzymatic protein hydrolysate from green microalga Chlorella vulgaris (Cv-PH) on the nutritional recovery of malnourished Balb/c mice after a 3-day fasting period. Mice were refed with commercial diet supplemented or not supplemented with Cv-PH (500 mg/kg) for 8 days. Regardless of the diet used during refeeding, animal body weights and serum protein concentrations did not differ between groups. Mice given Cv-PH had a significant increase in hemoglobin concentrations. Most serum amino acid levels were similar in the control and Cv-PH animals. Starved mice refed with Cv-PH showed normal liver functions, as judged by liver weight, protein concentration, and the enzymatic activities of cholinesterase and arginase. Cv-PH increased DNA, protein content, and gutmucosal weight. In addition, brush-border oligosaccharidase activities were also higher in the Cv-PH group. These findings suggest that Chlorella protein hydrolysate can be used to develop specific formulations suitable for pharmacologic nutrition.
Luis Humberto Delgado-Rangel,Julia Hernández-Vargas,Marymar Becerra-González,Ataúlfo Martínez-Torres,Evgen Prokhorov,J. Betzabe González Campos 한국섬유공학회 2019 Fibers and polymers Vol.20 No.12
The combination of collagen (CG), chondroitin sulfate (CS), and hyaluronic acid (HA) with poly(vinyl alcohol)(PVA) was explored to produce 3D tri-component scaffolds with enhanced mechanical properties and potential use in tissueengineering. The CG/PVA/CS and CG/PVA/HA electrospun scaffolds were crosslinked with citric acid, a cytocompatiblecrosslinker, which induced improved mechanical properties in both dry and wet state, especially with large elongation atbreak in the wet state. Ultimate tensile stress under the dry and wet state are significantly higher than those previouslyreported about collagen based nanofibers. IR, DSC and dielectric analysis demonstrated homogenous blending without phaseseparation and strong interactions between components. All scaffolds had swelling pH-sensitive behavior, making thempromising materials for drug delivery systems. The nanofiber mats permitted adhesion and proliferation of human embryonickidney cells; this cell line formed clusters that adapted well to the mats’ surface, through which the cells extended theirprocesses.
Jorge Humberto Dias 강원대학교 인문과학연구소 2015 Journal of Humanities Therapy Vol.6 No.1
This text is the English translation of a resume we made to the doctoral thesis that we presented in February, 2013 at the New University of Lisbon in Portugal. We had also drawn up a structural adjustment, to make possible the publication of this text in the Journal. This is the first thesis developed in Portugal on the basis of a theory for philosophical counselling, based on the work of a Spanish philosopher, Julián Marías, and crossing a theme, happiness, regarded as the great purpose of life and of philosophical counselling. To read more information about the “PROJECT@” method (created by me) in more detail, we suggest the consultation of the bibliography and the footnotes. The innovative nature of our academic text and the fact that this is still only known in the Portuguese language, we consider very important the knowledge of the international community, so that we can open a wider debate as well as a enrichment of our research line.
Effect of sterilization on 3-point dynamic response to in vitro bending of an Mg implant
Luis Humberto Campos Becerra,Marco Antonio Loudovic Hernández Rodríguez,Raúl Lesso Arroyo,Hugo Esquivel Solís,Alejandro Torres Castro 한국생체재료학회 2021 생체재료학회지 Vol.25 No.2
Background: The aim of the study is to characterize a biomedical magnesium alloy and highlighting the loss of mechanical integrity due to the sterilization method. Ideally, when using these alloys is to delay the onset of degradation so that the implant can support body loads and avoid toxicological effects due to the release of metal ions into the body. Methods: Standardized procedures according to ASTM F-1264 and ISO-10993-5 were used, respecting detailed methodological controls to ensure accuracy and reproducibility of the results, this testing methodology is carried out in accordance with the monographs of the Pharmacopoeia for the approval of medical devices and obtaining a health registration. An intramedullary implant (IIM) manufactured in magnesium (Mg) WE43 can support loads of the body in the initial period of bone consolidation without compromising the integrity of the fractured area. A system with these characteristics would improve morbidity and health costs by avoiding secondary surgical interventions. Results: As a property, the fatigue resistance of Mg in aggressive environments such as the body environment undergoes progressive degradation, however, the autoclave sterilization method drastically affects fatigue resistance, as demonstrated in tests carried out under in vitro conditions. Coupled with this phenomenon, the relatively poor biocompatibility of Mg WE43 alloys has limited applications where they can be used due to low acceptance rates from agencies such as the FDA. However, Mg alloy with elements such as yttrium and rare earth elements (REEs) have been shown to delay biodegradation depending on the method of sterilization and the physiological solution used. With different sterilization techniques, it may be possible to keep toxicological effects to a minimum while still ensuring a balance between the integrity of fractured bone and implant degradation time. Therefore, the evaluation of fatigue resistance of WE43 specimens sterilized and tested in immersion conditions (enriched Hank’s solution) and according to ASTM F-1264, along with the morphological, crystallinity, and biocompatibility characterization of the WE43 alloy allows for a comprehensive evaluation of the mechanical and biological properties of WE43. Conclusions: These results will support decision-making to generate a change in the current perspective of biomaterials utilized in medical devices (MDs), to be considered by manufacturers and health regulatory agencies. An implant manufactured in WE43 alloy can be used as an intramedullary implant, considering keeping elements such as yttrium-REEs below as specified in its designation and with the help of a coating that allows increasing the life of the implant in vivo.