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Shiqi Liu,Huanling Wang,Weiya Xu,Zhichao Cheng,Zhipeng Xiang,Wei-Chau Xie 대한토목학회 2020 KSCE JOURNAL OF CIVIL ENGINEERING Vol.24 No.11
Soil-rock mixture is a widely distributed geological material in mountainous regions, where slope stability is an important issue. To investigate the influence of rock on slope stability, firstly, rocks in SRM are generated and then SRM slope models are simulated based on the finite difference method (FDM). The impact of various characteristics of rocks on slope factor of safety (FOS) is studied systematically by using the reduced strength method. The characteristic of rock considered include rock content, number of rock edges, aspect ratio, rock size and inclination of rock. The simulations indicate that increasing the rock content can prevent the development of high strain region and improve slope stability. However, the aspect ratio of rock has negligible impact on the mean value of FOS. For slopes with 45o slope angle, rocks with 45o angle of inclination result in smooth potential sliding surface, whereas rocks with 135o angle of inclination lead to more tortuous potential sliding surfaces. Statistical indices are utilized to analyze the results of numerical modelling.
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Ailin Xia,Huanling Zhang 한국물리학회 2010 Current Applied Physics Vol.10 No.3
Zn(OH)2 is a kind of amphoteric compound. Therefore, for chemical coprecipitation method, the precipitation of Zn2+ ions may be incomplete if using NaOH as precipitator. In this study, single-phase powder specimens with a nominal composition Ni0.2Zn0.6Cu0.2Fe2O4 were prepared with chemical coprecipitation method, and the effects of excessive Zn2+ content (x, x = 3%, 5%, 7%, 9%) in working solution on intrinsic magnetic and structural properties were studied by vibrating sample magnetometer and X-ray diffractometer,respectively. It was found that the magnetization when Hm = 398 kA/m (5000 Oe) reached a maximum when x = 5%, and then decreased with the increase of x, which was attributed to the effect of different amount of Zn2+ in A sites on the A–B and B–B exchange interaction. Moreover, it was found that the lattice parameter was affected by the Zn2+ and Fe3+ ions due to their different ion radius to a certain extent.
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Anisotropic Characteristic of Irregular Columnar-jointed Rock Mass Based on Physical Model Test
Zhinan Lin,Weiya Xu,Huanling Wang,Jiuchang Zhang,Wang Wei,Rubin Wang,Hua Ji 대한토목학회 2017 KSCE JOURNAL OF CIVIL ENGINEERING Vol.21 No.5
Columnar joint is a special geological structure with self-organized joint network which separates the rock into an assemblage of blocks. The mechanic characteristics of irregular columnar-jointed rock mass (ICJRM) are dependent not only on the intact rock material but also on unique types of columnar joints. In effort to understand the anisotropic mechanic characteristics of ICJRM by the inherent anisotropic nature of the jointed structure, we conducted a series of uniaxial compression tests. Experiments were performed on an artificial ICJRM of 50 mm in diameter and 100 mm high. The “intact material” consisted of cement mortar and the columnar joints of photosensitive resins. The columnar joint in the specimen was made into six different orientations: 0°, 30°, 45°, 60°, 75°, and 90°, respectively, so observe the deformation behavior and failure modes of ICJRM with different various angles between the loading orientation and columnar joint were observed. Based on the analysis of the test results, the uniaxial compression strength and elastic modulus of ICJRM showed strong anisotropic behavior along with a special “U” shape in response to the angle between the loading orientation and columnar joint. Furthermore, the failure modes of ICJRM was observed.
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Weiwei Ma,Bingjie Ding,Huanling Yu,Linhong Yuan,Yuandi Xi,Rong Xiao 한국식품영양과학회 2015 Journal of medicinal food Vol.18 No.3
Genistein (GEN), a major soybean isoflavone (SIF), might possess neuroprotective properties through its antiinflammatory activity. We hypothesized that GEN could prevent the inflammatory damage detected in C6 cells induced by β-amyloid peptides 25-35 (Aβ25-35). Accordingly, we evaluated the inflammatory damage induced by Aβ25-35 and the protective effect of GEN against Aβ25-35 in C6 cells. In our study, the C6 glial cells (rats glioma cell lines) were preincubated with or without GEN for 2 h following incubation with Aβ25-35 for another 24 h. Then, methylthiazolyl tetrazolium (MTT) assay was used to assess the cell viability. Immunofluorescence staining was used to identify the C6 cells. Inflammatory factors tumor necrosis factor (TNF)-α and interleukin (IL)-1β were analyzed by using enzyme-linked immunosorbent assay (ELISA). Western blot analysis and reverse transcription-polymerase chain reaction analysis were performed to assess the expression of Toll-like receptors 4 (TLR4), inhibitor of kappaB-alpha (IκB-α). The current results showed that GEN could alleviate Aβ25-35-induced cell apoptosis and prevent Aβ25-35-induced TNF-α and IL-1β release from C6 cells. In addition, GEN prevented Aβ25-35-induced upregulation of the gene and protein expression of TLR4, and GEN significantly upregulated the expression of IκB-α in C6 cells damaged by Aβ25-35. These results suggest that GEN can alleviate the inflammatory stress caused by Aβ25-35 treatment, which might be associated with the neuroprotective effect of GEN regulating the TLR4/NFκB signaling pathway.
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Zhinan Lin,Weiya Xu,Wei Wang,Huanling Wang,Rubin Wang,Hua Ji,Jiuchang Zhang 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.9
The strength behavior and deformation modulus of columnar jointed rock mass have been investigated by conducting a series of uniaxial compressive tests, along with consideration of columnar joint effect. The tests have been performed on the artificial physical model samples, incorporating different angles β (which was the between the loading direction and axial direction of the columns) and heights of specimen. Columnar joint is a special geological structure with self-organized joint network which separates the rock into an assemblage of blocks. Due to the special joint network, the anisotropic characteristics of columnar joint rock mass is very remarkable. The physical model consisted of “intact rock” and “jointed filler”, replaced by cement mortar and white cement, respectively. The angle β were set to 0°, 15°, 30°, 45°, 60°, 75° and 90°, respectively, and the heights of specimen were set to five different values. Through the test, failure strength and failure modes of columnar joint rock mass with different angles β were observed. Based on the analysis of the test results, the uniaxial compression strength and average modulus of columnar joint rock mass showed strong anisotropy, showing a special “U” shape in terms of loading orientation. The size effect of columnar jointed rock mass was very typical, and the failure mode of columnar joint rock mass were analyzed. Furthermore, the relationship between failure strength and joint factor was studied.
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Atmospheric Research by Lidar at Anhui Institute of Optics and Fine Mechanics, China
Shunxing Hu,Tao LI,Jun Zhou,Huanling Hu,Yonghua Wu 慶熙大學校 레이저 工學硏究所 1999 레이저공학 Vol.10 No.-
Some lidar systems have been constructed for atmospheric research in Anhui Institute of Optics & Fine Mechanics (AIFOM), including L625 lidar, an UV-DIAL lidar, and a mobile dual-wavelength lidar, a Raman lidar. These lidar systems are used in measurements of the aerosol. and ozone profiles in stratosphere and troposphere, and water vapor in the air. A large number of data have been obtained.
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Permeability Anisotropy of Columnar Jointed Rock Masses
Lifang Zou,Weiya Xu,Guotao Meng,Yu Ning,Huanling Wang 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.10
This paper investigated the anisotropic permeability of columnar jointed rock masses at Baihetan hydropower station in Southwest China. Discrete element analysis is conducted to evaluate the hydraulic Representative Elemental Volume (REV) size of jointed rock masses. It is found to be 5m×5m and it is seven times of the column length. Research shows that permeability tensor of the jointed rocks exists. The maximum principle permeability is 3.47 × 10−14 m2 and the minimum principle permeability is 1.39 × 10−14 m2. The direction of maximum principle permeability is 72 degrees anticlockwise from the positive x- axis direction, which is along the same direction of the column length. A continuum hydro-mechanical coupling analysis is carried out on water infill of a tailrace tunnel in columnar basalt. An equivalent anisotropic mechanical model is applied in the numerical simulation. Anisotropic deformation and anisotropic permeability characteristics are investigated under the condition that the angle between maximum principle stress axis and maximum principle permeability axis is 72 degrees. Results show that anisotropic seepage field has an effort on anisotropic deformation field.
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( Fengcun Ji ),( Chao Lang ),( Pengfei Gao ),( Huanle Sun ) 한국미생물생명공학회(구 한국산업미생물학회) 2021 Journal of microbiology and biotechnology Vol.31 No.6
Previous studies have uncovered the role of circ_0000144 in various tumors. Here, we investigated the function and mechanism of circ_0000144 in gastric cancer (GC) progression. The expression of circ_0000144 in GC tissues and cells was detected through quantitative real-time polymerase chain reaction (qRT-PCR) method. Gain- and loss-of-function experiments including colony formation, wound healing and transwell assays were performed to examine the role of circ_0000144 in GC cells. Furthermore, western blot was conducted to determine the expressions of epithelial mesenchymal transition (EMT)-related proteins. The interaction between circ_0000144 and miR-217 was analyzed by bioinformatic analysis and luciferase reporter assays. The circ_0000144 expression was obviously upregulated in GC tissues and cells. Silencing of circ_0000144 inhibited cell proliferation, migration and invasion of GC cells, but ectopic expression of circ_0000144 showed the opposite results. Moreover, circ_0000144 sponged miR-217, and rescue assays revealed that silencing miR-217 expression reversed the inhibitory effect of circ_0000144 knockdown on the progress of GC. Our findings reveal that circ_0000144 inhibition suppresses GC cell proliferation, migration and invasion via absorbing miR-217, providing a new biomarker and potential therapeutic target for treatment of GC.
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