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      • Simulation of Poultry House Ventilation using Computational Fluid Dynamics

        ( Chih-hsiang Hsu ),( Sumingchen ),( Kuang-wen Hsieh ),( Chao-yin Tsai ),( Rou-yan Peng ),( Jin-ming Tsai ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1

        Poultry output value in Taiwan takes a large proportion of whole livestock production. However, in 2014, it was suffered from a serious bird flu invasion in Taiwan, culling a large number of poultries. Take geese as an example, almost 90% of the geese were culled in 2014. As a result, it caused serious losses to livestock industry. In order to prevent outbreak of bird flu, the government has stipulated that poultry houses must be rebuilt as non-open poultry houses and rehabilitated. Therefore, the development of the design in closed poultry houses is important. In this study, Computational Fluid Dynamics (CFD) was used to simulate a 30 m <sup>*</sup> 8.5 m <sup>*</sup> 3.6 m closed poultry house. There are two suction fans used for longitudinal ventilation. Through the different circulation fan setups to evaluate for the growth conditions of poultry and improve the ventilation of closed poultry houses, and reduce the possibility of invasion of pathogenic sources at the same time. The results showed when a circulation fan was not placed, there was a phenomenon of non-uniform airflow distribution within 6 m near water-cooled wall. When a circulation fan was placed 3 m away from the water-cooled wall, some parts of the airflow concentrated near the fan and caused non-uniform airflow distribution within 9 m near the water-cooled wall, which may be unsuitable for poultries living. The study showed that simulation of flow field facilitates designs of non-open poultry houses.

      • Prediction of Sugar and Acidity Contents in Pineapple using Near Infrared Spectroscopy

        ( Bo-an Shang Kuan ),( Suming Chen ),( Chao-yin Tsai ),( Chih-hsiang Hsu ),( Ha-chun Hsu ),( Yung-huei Chang ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1

        Pineapples are not only nutritious, but also have significant economic importance in Taiwan. Traditional technique used to determine the fruit’s quality is by hitting the fruit with palm. However, such method requires experience and is highly dependent on the condition of the fruit. More importantly, decisions made are often subjective. This research used near infrared spectroscopy to develop a fast and non-destructive method to measure the quality of pineapples. Tai-Nung No. 17 pineapple was used in this research to construct the calibration equation. During the experiments, pineapple samples are separated into three sections: top, middle, and bottom. Optical measurements are taken around each section in 90 degree increments, with a total of 131 samples. A multivariate model was then established by mathematical pre-treatments and modified partial least squared regression. Results showed strong correlation between constituents and optical spectrum, with a coefficient of determination r<sub>c</sub><sup>2</sup>=0.78,r<sub>p</sub><sup>2</sup>=0.747,SEP=1.142°Brix,RPD=1.803. Future experiment aims to increase the predictability of spectrum model by enhancing experimental methods, increasing sample size as well as minimizing experimental error.

      • KCI등재

        Magnolol induces apoptosis via caspase-independent pathways in non-small cell lung cancer cells

        Jong-Rung Tsai,Inn-Wen Chong,Yung-Hsiang Chen,Jhi-Jhu Hwang,Wei-Hsian Yin,Hsiu-Lin Chen,Shah-Hwa Chou,Chien-Chih Chiu,Po-Len Liu 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.4

        Magnolol, a hydroxylated biphenyl agent isolatedfrom herbal planet Magnolia officinalis, is a componentof traditional Asian herbal teas. It has been reported tohave anti-microbial, anti-inflammatory, and anti-canceractivity. Non-small cell lung cancer (NSCLC) cell lines(A549, H441 and H520) and normal human bronchialepithelial cells (HBECs) were used to evaluate the cytotoxiceffect of magnolol. We show that magnolol inhibitedcellular proliferation, increased DNA fragmentation, anddecreased mitochondrial membrane potential in all NSCLCcells, but had no cytotoxic effect on HBECs. Magnololtriggered the release of pro-apoptotic proteins: Bid, Bax and cytochrome c from mitochondria, but did not activatethe caspase-3, -8, and -9, suggesting that magnolol inducesapoptosis of NSCLC cell lines via a caspase-independentpathway. The caspase-independent pathway is mediatedthrough the activation of nuclear translocation of apoptosis-inducing factor, endonuclease G and cleaved poly(-ADP-ribose) polymerase, which played important roles inmediating cell death. Furthermore, magnolol inhibitedPI3K/AKT and ERK1/2 activity, but up-regulated p38 andJNK activity in A549 cell lines. The results of this studyprovided a basis for understanding and developing magnololas a novel treatment of NSCLC.

      • SCIESCOPUSKCI등재

        Magnolol induces apoptosis via caspase-independent pathways in non-small cell lung cancer cells

        Tsai, Jong-Rung,Chong, Inn-Wen,Chen, Yung-Hsiang,Hwang, Jhi-Jhu,Yin, Wei-Hsian,Chen, Hsiu-Lin,Chou, Shah-Hwa,Chiu, Chien-Chih,Liu, Po-Len 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.4

        Magnolol, a hydroxylated biphenyl agent isolated from herbal planet Magnolia officinalis, is a component of traditional Asian herbal teas. It has been reported to have anti-microbial, anti-inflammatory, and anti-cancer activity. Non-small cell lung cancer (NSCLC) cell lines (A549, H441 and H520) and normal human bronchial epithelial cells (HBECs) were used to evaluate the cytotoxic effect of magnolol. We show that magnolol inhibited cellular proliferation, increased DNA fragmentation, and decreased mitochondrial membrane potential in all NSCLC cells, but had no cytotoxic effect on HBECs. Magnolol triggered the release of pro-apoptotic proteins: Bid, Bax and cytochrome c from mitochondria, but did not activate the caspase-3, -8, and -9, suggesting that magnolol induces apoptosis of NSCLC cell lines via a caspase-independent pathway. The caspase-independent pathway is mediated through the activation of nuclear translocation of apoptosis-inducing factor, endonuclease G and cleaved poly(-ADP-ribose) polymerase, which played important roles in mediating cell death. Furthermore, magnolol inhibited PI3K/AKT and ERK1/2 activity, but up-regulated p38 and JNK activity in A549 cell lines. The results of this study provided a basis for understanding and developing magnolol as a novel treatment of NSCLC.

      • Study on a Wireless Environmental Monitoring System for Duck Incubator

        ( Rou-yan Peng ),( Suming Chen ),( Kuang-wen Hsieh ),( Chao-yin Tsai ),( Chih-hsiang Hsu ),( Jin-ming Tsai ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1

        Taiwan's domestic development of incubators are in simple structure, at low prices, and generally used by the industry. However, high number of regional dead eggs, the inability to understand the environmental conditions of incubator and other issues occurred frequently, resulting in operation and production difficulties. This research developed a wireless environmental monitoring system to collect data and upload to the cloud. A variety of environmental sensors and Raspberry Pi 3 were used in the establishment of wireless sensing module and environmental information detection platform. The environmental information was displayed in real-time and uploaded to the cloud. Computational fluid dynamics (CFD) was also used to simulate the internal flow field inside the incubator to determine the environmental control features, and control heating and humidification equipment with a PID controller. In this study, the establishment of wireless environmental monitoring system was completed. The wireless sensing module and the environment information detection platform have also been developed and tested. The stability of wireless sensing module was 98.5%, and the CFD simulation error was under 20%, which was low enough to predict the actual field temperature changes, and can be applied to the regulation of the incubator environment.

      • SCISCIESCOPUS

        Final report on international comparison APMP.QM-S4: Carbon dioxide in nitrogen at 2000 µmol/mol

        Rhoderick, George,Kim, Yong Doo,Kim, Kwang Seob,Lee, Sangil,Oh, Sang Hyub,Lin, Tsai-Yin,Cheng, Jui-Hsiang,Huang, Chiung-Kun Springer-Verlag 2014 METROLOGIA -BERLIN- Vol.51 No.-

        <P>This report presents the results of APMP.QM-S4, a supplementary comparison. This comparison is designed to test the capabilities of the NMIs to measure and certify carbon dioxide at a nominal amount fraction of 2000 µmol/mol in nitrogen. The previous key comparisons regarding carbon dioxide, CCQM-K1.b and CCQM-K52, had been done at a lower range than that in this comparison. This comparison gives an opportunity to the NMIs to submit supporting evidence for CMC at a higher range.</P><P>Main text.To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/.</P><P>The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).</P>

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