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Behaviour of CFST Stub Columns Subjected to Pure Compression
A. Horváth,D. Kollár,B. Kövesdi 한국강구조학회 2022 International Journal of Steel Structures Vol.22 No.4
Application of concrete-fi lled steel tubes (CFST) is becoming increasingly prominent in the civil engineering practice. However, the interaction of cross-sectional elements in CFST columns raises a number of questions, which have to be investigated in detail to improve design background and analytical resistance formulae. The aim of the current paper is to examine the structural behaviour of innovative concrete-fi lled steel tubes using diff erent structural steel grades (S355, S500 and S960) and concrete classes (C30/37 and C60/75). Combination of normal or high strength steel with normal or high-performance concrete is a novel research topic of composite structures resulting in economic and optimal design for distinct civil engineering applications such as buildings, bridges, towers and masts, etc. An advanced fi nite element model is developed and validated based on previous experimental results found in the international literature in order to investigate the discrepancies in structural behaviour, load-bearing capacity and failure mode of stub columns subjected to pure compression. Validated numerical results are compared to formulae-based resistances and the applicability of standardised design methods are examined. In addition, a novel formula is proposed considering hardening of steel material in accordance with EN 1993-1- 5. The developed formula can be used for the economic design of CFST stub columns, combining normal and high strength materials, where elastic shell buckling cannot occur ( D / t ≤ 90 ε 2 ).
Attila Horváth 한국세계문화사학회 2010 세계 역사와 문화 연구 Vol.0 No.22
역사적으로 중세 헝가리 대평원은, 그 면적의 2/3정도가 하천 간석지로, 경작 적지(適地)가 아니었기에, 오히려 독특한 활용형태로 발전하였다. 18‐19세기 헝가리 대평원과 소평원 대부분의 지역은 (현 헝가리 전체 국토 면적의 1/4에 달하는 지역) 하천 간석지였다. 헝가리 Szatmár 지역의 호두나무 군락지는 Tiszabecs로부터 Vásárosnamény까지 Tisza강을 따라 위치한다. 그 면적은 대략 9500 헥타르로, Szatmár의 전체 경작지에 있는 호두나무의 95%는 Tisza강 하천 간석지에 위치한다. 주변 자연환경적 특성에 적응된, 이 호두나무 지대는 우리가 하천 간석지 농업이라 부르는 복합적인 경작형태의 일부분이다. 이 전통적인 하천 간석지 농업의 핵심을 일명 notch 또는 natural drain‐farming system이라고 부른다. 이런 농업유형의 중요한 특징은 전적으로 자연적 자원들을 인식하고 활용하는 것에 기초하고 있다는 것이다. Notch는 지리학적인 범주일 뿐 아니라, 경제사적인 개념이기도 하다. 자연적인 배수 시스템의 역할, 그 활용 시도와 필요 충족의 결과로 그 가치를 인식하였다. 이러한 의미로 notch‐farming이라 부르는데, 고대 하천 저지대 농업을 위한 가장 중요한 토대를 만들어내었다. 호두나무는 하천 간석지 농업을 하는 사람들에게는 핵심적인 생계수단이었다. 그들에게 호두는 중요한 에너지원이었기 때문이다. 호두 알맹이는 쇠고기보다 약 7배 가량 칼로리가 뛰어나다. 비타민 B1과 B2를 함유하고, 건조된 알맹이는 단백질이 15‐25%, 지방이 50‐72%, 당분이 6‐13%이다. 호두는 훌륭한 현금자산이자, 그 목재는 큰 값어치가 있다. 하천 저지대 농업은 전적으로 자연과 조화를 추구하는 농업형태로, 하천의 범람으로 인해서 인간과 그 환경 사이에 균형을 만들어 내는 것이다. 또한 하천 저지대 농업은 유기농업을 위한 필요조건들을 전적으로 만족시킨다. Tisza강의 범람은 유기물질의 퇴적을 가져오고, 이는 토양을 위한 비료역할을 한다. 범람 이후 진흙은 질소함유량이 높은데, 이는 나무의 가지와 잎의 성장을 돕는다. 화학비료가 전혀 필요하지 않다. 하천의 범람은 토질개선을 위한 아무런 인공적인 조치가 필요치 않다. 퇴적은 토양 가운데 공기의 유통을 가져온다. 또한 범람은 산소부족으로 토양과 나무의 해충들을 제거하기 때문에 화학적인 살충이 필요하지 않다. 환경을 파괴하지 않고 계속해서 유지 가능한 고대의 자연협력적인 농업방식으로의 회귀는 상당히 많은 이점을 가져오리라 확신한다. 오늘날 환경론자들이 자연적인 순환과정을 따르되 절대 통제하려 하지 않는 notch‐farming을 강조하는 것은 우연이 아니다. 환경보호와 더불어 농업을 겸비할 수 있는 유일한 방법은 하천 간석지 농업방식에 대한 재고이다. 이와 같은 유형의 역사적인 경작방식이 카르파텐 분지의 자연적인 토대의 발전과 보호를 동시에 기할 수 있는 것이다. 그러한 경작방식의 붕괴와 사라짐은 자연적인 생태 시스템의 쇠퇴를 의미한다. 카르파텐 분지에서 생태학적으로 지속 가능한 살아있는 환경의 미래는 역사의 흔적이 되어버린 하천 간석지 경작 시스템에 대한 새로운 연구를 통한 자연과 협력하는 것에 달려있다.
Assessment of neutron-induced activation of irradiated samples in a research reactor
Harsányi Ildikó,Horváth András,Kis Zoltán,Gméling Katalin,Jozwiak-Niedzwiedzka Daria,Glinicki Michal A.,Szentmiklósi László 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.3
The combination of MCNP6 and the FISPACT codes was used to predict inventories of radioisotopes produced by neutron exposure of a sample in a research reactor. The detailed MCNP6 model of the Budapest Research Reactor and the specific irradiation geometry of the NAA channel was established, while realistic material cards were specified based on concentrations measured by PGAA and NAA, considering the precursor elements of all significant radioisotopes. The energy- and spatial distributions of the neutron field calculated by MCNP6 were transferred to FISPACT, and the resulting activities were validated against those measured using neutron-irradiated small and bulky targets. This approach is general enough to handle different target materials, shapes, and irradiation conditions. A general agreement within 10% has been achieved. Moreover, the method can also be made applicable to predict the activation properties of the near-vessel concrete of existing nuclear installations or assist in the optimal construction of new nuclear power plant units.
Recent Advances in the Neoadjuvant Treatment of Breast Cancer
Gábor Rubovszky,Zsolt Horváth 한국유방암학회 2017 Journal of breast cancer Vol.20 No.2
In the last few decades, neoadjuvant therapy for breast cancer has gained considerable therapeutic importance. Despite extensive clinical investigations, it has not yet been clarified whether neoadjuvant therapy would result in improved survival in comparison with the standard adjuvant setting in any subgroups of patients with breast cancer. Chemotherapy is especially effective in the treatment of endocrine insensitive tumors, and such therapeutic benefit can be assumed for patients with triple-negative, or hormone receptor-negative and human epidermal growth factor receptor 2 (HER2)-positive breast cancer. However, dose escalation, modification of the therapeutic regimens according to early tumor response, as well as the optimal sequence of administration are still matters of debate. There is a current debate between clinical experts regarding the concomitant and sequential administration of carboplatin and capecitabine, respectively, as part of the standard neoadjuvant treatment, as well as the use of bevacizumab, as part of the preoperative treatment. In case of HER2 positive tumors, an anti-HER2 agent can be administered as part of the preoperative treatment, and according to preliminary clinical data, dual HER2 blockade can also be reasonable. Further, chemotherapy-free regimens can be justified in highly endocrine sensitive tumors, while immune modulating agents may also gain particular importance in the case of certain subtypes of breast cancer. Several small-molecule targeted therapies are under clinical investigation and are expected to provide new neoadjuvant treatment options. However, novel, more predictive biomarkers are required for further evaluation of the neoadjuvant therapies, as well as the effect of novel targeted agents intended to be incorporated into neoadjuvant therapy.
Sirasak Tepjit,Imre Horváth, Zoltán Rusák 한국CDE학회 2019 Journal of computational design and engineering Vol.6 No.4
Smart CPSs (S-CPSs) have been evolving beyond what was identified by the traditional definitions of CPSs. The objective of our research is to investigate the concepts and implementations of reasoning processes for S-CPSs, and more specifically, the frameworks proposed for the fuzzy front end of their reasoning mechanisms. The objectives of the paper are: (i) to analyze the framework concepts and implementations of CPS, (ii) to review the literature concerning system-level reasoning and its enablers from the points of view of the processed knowledge, building awareness, reasoning mechanisms, decision making, and adaptation. Our findings are: (i) awareness and adaptation behaviors are considered as system-level smartness of S-CPSs that are not achieved by traditional design approaches; (ii) model-based and com-posability approaches insufficiently support the development of reasoning mechanisms for S-CPSs; (iii) frameworks for development of reasoning in S-CPS should support compositional design. Based on the conclusions above, we argue that coping with the challenges of compositionality requires both software-level integration and holistic fusion of knowledge by means of semantic transformations. This entails the need for a multi aspect framework that is able to capture at least conceptual, functional, architectural, informational, interoperation, and behavioral aspects. It needs further investigation if a compositionality enabling framework should appear in the form of a meta-framework (abstract) or in the form of a semantically integrated (concrete) framework.
Carbon dioxide reforming of methane over Ni–In/SiO2 catalyst without coke formation
Johanna Károlyi,Miklós Németh,Claudio Evangelisti,György Sáfrán,Zoltán Schay,Anita Horváth,Ferenc Somodi 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.58 No.-
It was found that coke formation on Ni/SiO2, used in dry reforming of methane, can be eliminatedcompletely by addition of indium to the catalyst. The interaction of the two metals was suggested by theresults of TPR, CO-TPD and XPS measurements. The presence and uniform distribution of NiIn and Ni2Inalloy nanoparticles after reduction at 700 C of the calcined catalyst was shown by HAADF-STEM, HRTEMand EDX analysis. The indium atoms dilute the nickel surface inhibiting the formation of multiplebondedcarbon species thereby hindering the development of carbon nanostructures on the catalystsurface during dry reforming.
K. M. Faridul Hasan,Czók Csilla,Zsuzsanna Mária Mucsi,Zsófia Kóczán,Péter György Horváth,Miklós Bak,Tibor Alpár 한국섬유공학회 2022 Fibers and polymers Vol.23 No.12
The hybridization effect of sisal/cotton interwoven fabric backed by paper roving with jute woven material isinvestigated in the presence of polylactide (PLA) matrix. The biocomposites (five) were produced through varying different(100/0, 75/25, 50/50, 25/75, and 0/100) proportions of sisal/cotton with jute woven fabrics respectively in the laminates. Afterthe successful reinforcements, mechanical properties were investigated in terms of tensile and flexural tests. Moreover, thewater absorption, thickness swelling, and moisture content tests were also examined for assessing the physical anddimensional stability of developed hybrid composites. The water absorption and thickness swelling tests were carried out inthe presence of water after 2 h and 24 h immersion. The highest mechanical properties were found in case of 100 % sisal/cotton reinforced composites whereas the lowest value was observed in case of 100 % jute fiber. The morphological views ofthe developed materials were also characterized using SEM (Scanning electron microscopy) to observe the surfaces beforeand after the tensile load. The SEM deployed EDX (energy-dispersive X-ray) linear scanning was applied to explore thepresence of different chemicals in the biocomposite systems. The reinforcement effects of different fibers loading incomposite systems were also tested in terms of regression analysis and found that sisal/cotton interwoven fabrics existsignificant influence in the composite systems to increase the mechanical properties.
Gergely Temesi,Viktor Virág,Éva Hadadi,Ildikó Ungvári,Lili E Fodor,András Bikov,Adrienne Nagy,Gabriella Gálffy,Lilla Tamási,Ildikó Horváth,András Kiss,Gábor Hullám,András Gézsi,Péter Sárközy,Péter Ant 대한천식알레르기학회 2014 Allergy, Asthma & Immunology Research Vol.6 No.6
Purpose:Based on a previous gene expression study in a mouse model of asthma, we selected 60 candidate genes and investigated their possible roles in human asthma. Methods: In these candidate genes, 90 SNPs were genotyped using MassARRAY technology from 311 asthmatic children and 360 healthy controls of the Hungarian (Caucasian) population. Moreover, gene expression levels were measured by RT PCR in the induced sputum of 13 asthmatics and 10 control individuals. t-tests, chi-square tests, and logistic regression were carried out in order to assess associations of SNP frequency and expression level with asthma. Permutation tests were performed to account for multiple hypothesis testing. Results: The frequency of 4 SNPs in 2 genes differed significantly between asthmatic and control subjects: SNPs rs2240572, rs2240571, rs3735222 in gene SCIN, and rs32588 in gene PPARGC1B. Carriers of the minor alleles had reduced risk of asthma with an odds ratio of 0.64 (0.51-0.80; P=7×10-5) in SCIN and 0.56 (0.42-0.76; P=1.2×10-4) in PPARGC1B. The expression levels of SCIN, PPARGC1B and ITLN1 genes were significantly lower in the sputum of asthmatics. Conclusions: Three potentially novel asthma-associated genes were identified based on mouse experiments and human studies.