요중 N-acetyl-β-D-glucosaminidase 활성치를 이용한 신발제조업 근로자들의 만성 신기능 장애 평가

김돈균,이수일,조병만,이지호,이후락,박종욱 大韓産業醫學會 1993 대한직업환경의학회지 Vol.5 No.1

부산지역 신발제조업 근로자중 유기용제에 폭로되고 있는 150명을 폭로군으로 하고, 일반사무직 근로자 53명을 대조군으로 하여 인적특성, 직업에 대한 만족도, 자각증상, 작업과 관련된 스트레스의 정도를 조사하고, 유기용제 폭로량의 지표가 되는 요중 마뇨산 및 근로자 건강진단 항목인 혈중 요소질소, 혈청 크레아티닌 그리고 조기 신기능 장애의 지표로 알려진 요중 NAG 활성치를 측정하여 얻은 바를 아래와 같이 요약한다. 1. 요중 NAG 활성치는 폭로군에서 4.63U/g creatinine, 대조군에서 2.95U/g creatinine로 폭로군에서 높게 측정되었고(p<0.05), 유기용제 폭로에 의한 신기능 변화에 민감한 결과를 보였다. 2. 설문조사에서 직업에 대한 불만족, 이직을 원하는 경우, 건강에 대한 염려, 직업과 관련된 스트레스 및 유기용제 폭로와 관련된 증상호소가 대조군에 비해 폭로군에서 유의하게 증가되어 있어(p<0.05), 유기용제에 폭로되고 있는 신발제조업 근로자들의 보건관리는 산업보건학적 측면에서 매우 중요한 것으로 나타났다. 3. 폭로군중 근무기간 5년 이상인 대상자에서 요중 NAG 활성치는 5.92U/g creatinine, 근무기간 5년 미만인 경우 4.34U/g creatinine으로, 유기용제 폭로 기간이 길어짐에 따라 요중 NAG활성치는 통계학적으로 유의하게 증가되어 있었다(p<0.05). 4. 요중 NAG활성치는 근무기간을 가중한 톨루엔 총 폭로량과 유의한 정의 상관관계를 보여(p<0.05), 용량-반응관계를 보여 주었다. 이상의 결과에서, 복합유기용제에 만성적으로 폭로되는 근로자들에 공통적으로 발생할 수 있는 조기 신기능 장애를 감시하기 위하여, 요중 NAG활성치를 측정한 자료를 이용하면 유기용제 폭로 근로자들의 보건관리를 위하여 자료를 제공할 수 있을 것으로 생각된다. Personal characteristics, degree of satisfaction for work, subjective symptoms, and stress related to working condition were investigated from 150 workers exposed to organic solvents in shoe factories and 53 official workers in Pusan area, and urinary hippuric acid concentration which represented the amount of exposed organic solvents, BUN and serum creatinine which were renal function tests for worker's health examination and urinary N-acetyl-β-D-glucosaminidase activity were measured. The results obtained were summarized as follows. 1. The mean value of urinary NAG activity of exposed group was higher than that of control group(p<0.01), and subjects whose NAG activities were over refrence range in exposed group were far more than in control group(p<0.05), therefore urinary NAG activity was a sensitive test for the change of renal function due to exposure of organic solvents. 2. Unsatisfaction for occupation, want to change occupation, worry about health, stress related to job and symptoms related to exposure of organic solvents investigated by questionnaire were higher in exposed group than in control group, therefore the health management for workers exposed to organic solvents in shoe factories was important in the viewpoint of occupational medicine. 3. The mean value of urinary NAG activity in the subjects whose working duration were over 5 years was higher than in the subjects whose working duration were over 5 years was higher than in the subjects whose working duration were under 5 years, therefore the longer exposured duration was, the higher urinary NAG activity was. 4. Urinary NAG activity had positive correlation with time weighted amount of total toluene exposure therefore dose-response relationship was suspected. As above results, it will be very useful to apply the data of urinary NAG activity to the health management of workers exposed to orgaic solvents in order to monitoring of early renal dysfunction which was common in the workers chornically exposed to mixed organic solvents.

營農類型別 農業所得의 隔差要因分析 : 河東部 3 個 部落을 중심으로 A Survey of Three Villages in Hadong-gun

金永暾,金厚根 慶尙大學校 1985 論文集 Vol.24 No.2

The present study has been performed postulating that we are able to increase income in a limited area of crop land by improving the type of farming and making use of family labor time. In an attempt to test the my hypothesis, three typical villages with the similar farm size but different type of farming have been selected. The results obtained in the survey are summarized as follows. 1) There are no differences between the size of crop land and numbers of farmers in the selected three villages. In addition, the farms have similar economic background and farming conditions. 2) Though the general food grain village still keep growing only rice and barley with the traditional type of farming, the other farms(villages) have changed to livestock farm by importing beef cattles since 1970. Improving the old style of farming the present major portion of job was livestock farming and minor, crop farming. Further a third type of farming, has been observed that have improved the old type of farming by employing both the multi-culture farming system and vinyl house. .3) Food grain village farmers cultivate rice and barley. But livestock farm village grow the rice and forage crops. Advanced horticulture farming farmer cultivate rice and horticulture instead of cultivating barley in the winter and spring season. 4) The cropping systems on non-paddy land in food grain village are crops and barley but livestock farmers produce mainly forage during the seasons. Vinyl house farmers regard horticulture farming as their main income source but summer crops only their family requirements. 5) It was found that the size of crop land surveyed on the three villages appeared similar in each other, but its labor input was shown to be remarkly different by their type of farming. The average labor input an livestock village and those an vinyl house farmer have been increased 60 percent and 70 percent, respectively, comapring with food grain village. 6) The ratio of fixed capital turned out to be the highest in livestock village. 7) The component-ratio of farm expenses is very different. In crop-major the component ratio of farm expenses shows the high figure of 44. 1 percent. It shows the lower in the other villages. 8) The farms with similar size of crop land but being improved in type of farming brought about a great differences in average farm income.. The average income of 350,000 Won in food grain village have been in comparison with that of 870,000 Won in livestock village and that of 760,000 Won in vinyl house village. 9) The factors of increasing farm income prove to be as follows. 1. To cultivate economic crops. 2. To use more labor hour. 3. Utilization of by-products. 4. To promote efficiency of land utility, such as 168 percent in food grain village, 180 percent in livestock village, 360 percent in vinyl house village. 10) From the result of determinant for increasing farm income by type of farming, crop land is measured as a critical factor of increasing farm income at the food grain village, and farm land, farm labor hours and other capital inputs have equally contributed to increase farm income at livestock village. Farm labor hours is measured as a important factor to improve farm income at the vinyl house village.

Helicobacter Pylori 감염의 유병률과 위험요인에 관한 연구

이후락,김영욱,김돈균 대한보건협회 1999 대한보건연구 Vol.25 No.1

H. pylori 감염은 만성위염과 소화성 궤양의 원인인지로 작용하며 위암발생과도 밀접한 관련성이 있는 것으로 증명되어 기존의 위·십이지장 질환의 치료와 관리에 많은 변화를 가져오고 있다. 저자는 H. pylori 감염의 유병률을 추정하고 감염과 관련되는 위험요인을 조사할 목적으로 부산광역시와 경상남도에 거주하는 소아, 청소년 및 성인 1,466명을 대상으로 1996년 4월부터 8월에 걸쳐 본 연구를 시행했다. 연구대상자들의 혈청에 존재하는 H. pylori IgG 항체는 Enzyme Linked immunosorbent Assay(ELISA) 방법으로 측정했으며 설문조사를 통해 기본적인 인구학적 특성, H. pylori 감염과 관련되는 요인에 관한 정보를 얻었다. 연구대상자들의 총 H. pylori 감염률은 33.1%였고 이를 1996년 한국표준인구로 환산한 연령보정 표준화 유병률은 51.5%로 우리나라 사람의 반 이상이 H. pylori에 감염되어 있는 것으로 추정된다. 성별 연령보전 표준화 유병률은 남자49.8%, 여자 53.7%로 여성이 남성보다 약간 높았다. 연령군별 H. pylori 감염률은 1∼9세군의 10.0%에서 60세 이상군의 76.1%까지 연령이 증가함에 따라 유병률도 비례해 증가하는 양상을 보였다(x2 for trend=460, p<0.0001). 특히, 1∼3세 연령군에서 학동기전 연령인 4∼6세군간에 유병률의 차이가 없으나 초등학교 1, 2, 3 학년 연령인 7~9세군 간에 갑작스런 유병률의 상승이 관찰되어 이 시기부터 H. pylori 감염이 본격적으로 시작되는 것으로 추측된다. 소아 및 청소년의 경우, 다변량 로짓 희귀 모델에서 연령과 가족수가 H. pylori 감염과 유의한 상관관계를 보였으며 특히, 연령은 1∼3세에 비해 16∼19세 군의 교차비(95% 신뢰구간)가 7.1(1.9-26.3)로 H. pylori 감염의 가장 강력한 예측인자인 것으로 나타났다. 가족수 1∼3명을 기준으로 4∼5명의 교차비는 2.0(1.0-4.0), 6명 이상의 교차비는 2.8(1.3-6.0)이었다. 성인의 경우 소아 및 청소년에서와 마찬가지로 연령과 가족수가 H. pylori 감염의 유의한 위험요인 이었다. Helicobacter pylori is now recognized as a causative agent of chronic gastritis and peptic ulcer, and strongly associated with the development of gastric carcinoma, by the sensitive and specific serologic ests to indentify the individuals infected with Helicobacter pylori, the epidemiologic features of this diseases have been investigated. But its transmission route is not established, yet. The purposes of this study is to estimate the prevalence of Helicobacter pylori infection in health children and adults and to evaluate the risk factors for Helicobacter pylori infection in Korea. The observed overall seropositivity rate, as determined by detecting IgG antibodies to Helicobacter pylori by using ELISA. was 33.1% and the age adjusted standardized prevalence rate was 51.5%. Also, age adjusted sex-specific standardized prevalence rates were 49.8% in male and 53.7% in female. The prevalence rate was increased progressively from 10.0% in the age group 1~9 years to 76.1% in the age group above 60 years(x2 for trend=460, p<0.001). Especially, the rate increased abruptly from 6.3% in the age group 4~6 years to 13.8% in the age group 7~9 years, and this suggested that elementary school age would be the beginning time of Helicobacter pylori infection in good earnest. In case of age group 1~19 years, age and the numbers of family member in the house were statistically significant risk factors for Helicobacter pylori infection in multivariate logistic regression model. Especially, adjusted odds ratio(95% CI) for Helicobacter pylori infection in the age group 16~19 years referent to age group 1~3 years was 7.1(1.9-26.3), so age was the strongest predictive factor for Helicobacter pylori infection. In case of age group more than 20 years, age and number of family members were statistically significant risk factors for Helicobacter pylori infection in multivarite logistic regression model.

Selective Laser Melting of Fe-Ni-Cr Coating on AISI H13 Tool Steel

Byeong don Joo,Jeong Hwan Jang,Jae Hoo Lee,Young Myung Son,Young Hoon Moon 한국표면공학회 2008 한국표면공학회 학술발표회 초록집 Vol.2008 No.-

Fucoidan Prevents the Progression of Osteoarthritis in Rats

Lee, Don-Gil,Park, Sang-Yong,Chung, Won-Seok,Park, Jae-Hee,Hwang, Eunson,Mavlonov, Gafurjon Tom,Kim, In-Ho,Kim, Ki-Young,Yi, Tae-Hoo Mary Ann Liebert 2015 Journal of medicinal food Vol.18 No.9

Xe gas %에 따른 AC PDP의 방전특성 고찰

이돈규(Don-Kyu Lee),이선홍(Sun-Hong Lee),이호준(Ho-Jun Lee),박정후(Chung-Hoo Park) 대한전기학회 2003 대한전기학회 학술대회 논문집 Vol.2003 No.10

0.5% 고비중 Bupivacaine 과 Tetracaine을 사용한 척추 마취의 비교

이후전,류지한,심규호,전병돈,이신우,태일산 대한마취과학회 1997 Korean Journal of Anesthesiology Vol.32 No.1

Several methods for the management of intractable pain for various conditions including malignant disorders, herpes zoster, and low back pain and/or sciatica in 80 patients were described and analyzed. Neurolytic blocks of celiac plexus were given to the patients suffering from intra-abdominal pain from malignant origin or chronic pancreatitis. Herpes zoster was treated mainly by chemical sympathectomy via paravertebral route and occassionaly corticosteroid was administered epidurally with the local anesthetic, bupivacaine. All the patients with low back pain and/or sciatica were given epidural corticosteroid one to three times. Other peripheral verve blocks and regional corticosteroid therapy were given to the rest of the patients. Fair to excellent result was obtainde in 71% of the patients but the response was poor in the remaining 28% of the patients. It seems that earlier the patients were referred to the pain clinic, the better the results were.

Alveolar Bone Protective Effect of Hiziki Extracts on the Progression of Periodontitis

Lee, Don-Gil,Shin, Yu-Kyong,Park, Jae-Hee,Park, Sang-Yong,Hwang, Eunson,Yang, Jung-Eun,Jo, Hae,Kim, Ki-Young,Mavlonov, Gafurjon T.,Yi, Tae-Hoo Springer-Verlag 2018 Marine biotechnology Vol.20 No.3

Helicobacter Pylori 감염의 유병률과 위험요인에 관한 연구

이후락(Hoo Rak Lee),김영욱(Young Uk Kim),김돈균(Don Kyoun Kim) 대한보건협회 1999 대한보건연구 Vol.25 No.1

N/A N/A

Xe 분압비에 따른 AC PDP의 방전특성 연구

이돈규(Don-Kyu Lee),서동현(Dong-Hyun Seo),김동현(Dong-Hyun Kim),이호준(Hoo-June Lee),박정후(Jung-Hu Park) 대한전기학회 2003 대한전기학회 학술대회 논문집 Vol.2003 No.7