韓國 大學生의 運動後 臨床血液學的 變化 測定에 關한 硏究

양태홍 서울保健大學 1981 論文集 Vol.1 No.1

종합병원 방사선사의 근무환경에 따른 지역별 스트레스 수준 분석

정홍량,손부순 한국환경과학회 2005 한국환경과학회지 Vol.14 No.4

A survey was conducted to 890 radiological technologists working at 44 general hospitals of 16 cities and provinces across the county to determine their stress level according to regions divided into the capital city, metropolitan areas and small- and medium-sized cities. For this purpose, such factors as their working environment, role playing, job conflict and job burden were compared and analyzed according to the regions. The findings may be summed up as follows: 1. In terms of working environment, radiological technologists in the capital city were found to have the least stress(23.46), followed by those in metropolitan areas(24.53) and small- and medium-sized cities(24.85). There was a significant difference according to the regions as for the item 'worry about influence of radioactive contamination(genetic, decisive and plausible)(P<0.001 ). 2. As for role playing, radiological technologists in small-and medium-sized cities appeared to receive the highest stress(18.25) followed by metropolitan areas(17.71) and the capital city(16.69). There was a statistically significant difference(p<0.001) according to the regions 3. Regarding job conflict, those who work in small- and medium-sized cities turned out to get the highest stress(15.66) compared to those in metropolitan areas(15.35) and the capital city(14.44). In terms of job autonomy, there was no significant result from the survey in spite of the difference between metropolitan areas(14.87). small- and medium-sized cities(14.79) and the capital city(14.66). 4. Little difference was detected according to the regions as far as the job burden(excessive or too little) was concerned. But their was a significant regional difference in terms of patient-related factors with the capital city(11.50), small- and medium-sized cities(10.75), and metropolitan areas(10.63)(p<0.001).

CATCH22의 분자유전학적 특성에 관한 연구

길홍량,이영하,정용헌 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.2

To investigate molecular genetic characteristics of CATCH 22 syndrome, we studied the correlation between phenotype and target gene screening and mode of inheritance using FISH (fluroscence in situ hybridization) and STRP(short tandem-repeated polymorphism). Hemizygosity for a region of 22q11.2 was found in 21 CATCH 22 patients. 2 of 19 family (11%) had familial CATCH 22 syndrome and affected 2 parents were mothers. No familial cases were found among CATCH 22 syndrome with absent thymus/ DiGeorge syndrome. The conotruncai cardiac anomalies such as Tetralogy of Fallot and vascular anomalies were common among CATCH 22 syndrome. Both the STRP maker screening(D22S941) and FISH(D22S75) were efficient and useful for the detection of chromosome 22q11 deletion and the evaluation of parent of origin but show some heterogeniety. Markers D22S75 and D22S941 appear to be consistently hemizygous in patients with deletions, so it was very useful in screening the patients with the conotrucal cardiac anomalies.

심도자술 및 심혈관조영술을 시행한 소아 심혈관질환의 임상적 고찰

길홍량 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2

A clinical study was made on 195 patients with cardiovascular disease who were admitted to the department of pediatrics Chungnam National University Hospital & taken cardiac catherterization and cineangiography from March 1993 to December 1995. The results were as follows 1) The ratio of male to female was about 1 : 1 among 195cases, male 99 cases, female 96 cases. 2) The age distribution of the patients with cardiovascular disease was as follows ; 7.2% under 1 month of age, 35.4% under lyear of age, 80% under 5year of age, & 20% over 5year of age. 3) The distribution of cardiovascular disease in order of frequency as follows : VSD 42.6%, Tetrallogy of Fallot 11.3%, Patent ductus arteriosus 8.7%, Atrial septal defect 7.7%, Pulmonary stenosis 5.1%. 4) Kawasaki disease with aneurysm & transposition of grat arteries were appeared as male dominance. Patent ductus arteriosus was female preponderence. 5) The ratio of acyanotic to cyanotic congenital heart disease was 3.8 : 1. 6) Major complication during cardiac catheterization & cineangiography appeared in 19 cases (9.7%) : supraventricular tachycardia 9cases, bleeding requiring transfusion 5cases, & death 3 cases. The causes of death were cardiac perforation & arrythmia.

컬럼형 회분건조기를 이용한 벼의 건조에 관한 연구

변유량,최홍식,조형용,권윤중,김주봉 연세대학교 산업기술연구소 1984 논문집 Vol.16 No.1

The vertical column batch dryer which is suitable to Korean farm was constructed and dryer performance was investigated through field test. The effect of a drying air temperature and an airflow rate on the drying rate was studied, and an empirical drying equation was established. The average drying rate of paddy were 1.6-1.8%/hr at the air temperature of 43℃ and the airflow rates of 19.4 - 24.5 CFM/ft². The differences of grain moisture content between the inner and outer layer of vertical paddy bed were 0.5 - 0.9% The effect of a drying air temperature was larger at high airflow rate. At constant temperature, the drying rate was increased as an airflow rate was increased. The empirical drying equation could be expressed as followed: ??=0.9exp(??) Where K=3.22×?? The average whitening ratio of brown rice which was dried with column batch dryer was higher 0.6% than that of sun dried rice.

Anthracycline으로 치료한 소아암환아에서 Dobutamine 부하 심초음파를 이용한 심근기능의 평가

길홍량 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

Doxorubicin is a effective anticancer agent known to cause acute and chronic cardiotoxicity. To develop a more sensitive echocardiographic screening test for cardiac damage, a preliminary study was performed using dobutamine to differnentiate asymtomatic childhood patient treating with doxorubicin from healthy control subject. Echocardiographic data from the experimental group of 8 patients (mean age 7.9±4.8 years) treated from 0.2 to 3.2 year(meann 1.7year) before study with 250 to 502mg/㎡ of doxorubicin (mean 319) were compared with echocardiographic data from 8 normal age-matched control subjects, Graded dobutamin infusions of 2.5 and 5㎍/kg per min were administrated. Echocardiographic doppler studies were performed before infusion and after 15min of infusion at each rate. The most important findings were that compared with values in control subject, end-systolic left ventricular posterior wall dimension and percent of left ventricular posterior wall thickening in doxorubicin treated patients were decreased at baseline study and these findings were more clearly documented with dobutamine stress. End systolic left ventricular posterior wall dimension at baseline for the doxorubicin treated patients was 12±0.7mm vs 13.1±1.5mm for control (p<0.05). End-systolic left ventricular posterior wall dimension at the 5㎍/kg per min dobutamin infusion for the doxorubicin treated patients was 14.5±1.2mm vs 19.3±2.6 for control subjects(p <0.01). Percent left ventricualr posterior wall thickening at baseline study for the doxorubicine treated patient was 87±11% vs 97±13% for the control group(p<0.05). Percent left ventricular posterior wall thickening at the 5㎍/kg per min dohutamine infusion for the doxorubicin group was 113±11% vs 185±20% for the control group. These results suggest that evaluation of left ventricualr systolic function such as end-systolic posterior wall dimension and posterior wall thickening during isotropic stimulation provides a sensitive technique for exam ng the cardiac status of asymtomatic doxorubicine-treating patients.

가와사끼병에서 γ-글로블린 1회 대량요법과 분주요법의 치료 효과

길홍량 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

We studied 58 children , who were diagnosed as Kawasaki disease at department of ped. Chungnam university hospital from Jan,1990 to Nov. 1993. These cases were divided into two groups according to the mode of therapy administerated during acute phase : 18 cases in group A with a combination of intravenous gammaglobulin(2gm/kg single) and oral aspirin (100mg/kg/day) and 40 cases in group B treated with combination of intravenous gammaglobulin (400mg/kg/day 5 days)and oral aspirin. The clinical and echocardiographic findings were as follows 1) The age & sex distribution was comparable in both groups : the mean age was 30.0± 17.8 months for group A and 35.6± 28.7 months for group B. There were 13 boys and 5 girls in group A and 28 boys and 12 girls in group B. 2) Single high dose gammaglobulin was started at 6.1± 2.1 days in group A and at 6.1± 2.6 days in group B after onset of illness. 3) No significant difference was noted in the hemoglobin, WBC count, platelet count & ESR during course of disease. 4) The echocardiographic abnormalities at 2 month after onset were noted in 3 cases (16.6%) out of 18 cases in group A and in 10 cases (25.0%) out of 40 in group B. The author concluded that single high-dose intravenous gammaglobulin compared to splitted dose of that, is safe and effective in reducing the clinical findings including the fever and the prevalence of coronary abnormalities.

심근의 단독 비경화증(Isolated Noncompaction of Ventricular Myocardium)의 임상 양상

문은경,이훈영,장미영,길홍량,정용헌 대한소아과학회 2002 小兒科 Vol.45 No.12

고위험군 가와사끼병에서 스테로이드 추가 요법의 효과

강선미,문은경,인수미,길홍량 대한소아과학회 2002 小兒科 Vol.45 No.12

가와사키병 환아중 치료 실패 및 재발하는 환아의 위험 인자

이훈영,김재철,이재호,길홍량 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

Several cases of Kawasaki disease(KD) were unresponsive to the initial treatment with intravenous immunoglobulin(IV1G). We retrospecitvely analyzed all children admitted with KD to determine the occurrence and variables associated with the initial IVIG treatment failure. All patients who were diagnosed for KD and atypical KD between January 1995 and December 2002 were enrolled. A total of 235patients were enrolled during the study period. All patients had been treated with IVIG and high dose ASA in acute phase. 196 patients had a normal baseline echocardiogram before treatment. 12 patients(6.1%) of them had developed the new coronary abnormalities after treatment. We divided the patients into two group : Treatment success group(n=184) vs. treatment failure group(n=12). Patients who were younger and had few numbers of symptom and longer duration of fever after treatment, a high CRP, a high Harada score were at risk of failure to respond to IVIG treatment. We found no correlation among gender, WBC count, hematocrit,albumin,erythrocyte sedimentation rate (ESR) with failure of the initial IVIG treatment. We found that treatment failure was more common in atypical KD and high Harada score group.