정상청력인에서 나이와 성별에 따른 DPOAE의 특성

홍빛나,남상길,김진숙 한국음성과학회 2004 음성과학 Vol.11 No.4

The primary goal of the present study was to explore more detailed evidence for the influence of aging and gender effects on the capability of Korean healthy, ears to generate DPOAEs. DPOAEs were examined in series of human subjects, with clinically normal hearing, ranging in age from 10 to 65 years. All 60 Koreans were divided into 6 age groups. Each age group included 10 participants, 5 females and 5 males. The gender effects on the difference between the absolute amplitude and noise floor value in DPOAEs did not exist. The difference increased as the frequency increased. The aging effects on the difference between the absolute amplitude and noise floor value in DPOAEs did exist. The difference increased as the frequency increased but orderly age effects could not be found. The principle finding was that, when compared between emissions in young and old ears, DPOAEs accurately tracked the systematic deterioration of high-frequency hearing in aging individuals. Such results support the need to reestablish the criterion for interpretation of DPOAEs in the elderly.

ICP-AES를 이용한 마그네시아 중의 미량성분 분석

임흥빈,김인숙,김혜영,김경희 단국대학교 1999 論文集 Vol.34 No.-

The sample pretreatment technique using an atmospheric pressure acid digestion for the analysis of magnesia that is a representative material for fine refractory was studied. When magnesia was dissolved by four kinds of acids . i. e.. hydrochloric acid, nitric acid, perchloric acid + hydrochloric acid, phosphioric acid + nitric acid, the intensity change of Cr. B. Fe. Ca. Al were observed by ICP-AES. And, the recovery was measured by spiking the standard solution of 100ppm, the results indicate that the loss of most of elements is 8∼32% for hydrochloric acid and 7∼26% for nitric acid. The recovery is relatively lower value compared to that of perchloric acid+hydrochloric acid(1+2) and phosphoric acid+nitric acid(1+2), of which the recovery is more than 95% for most of elements. Magnesia single crystal and powder were quantitatively analyzed by a standard addition method after optimizing in sample pretreatment using HClO4 + HCl.

n-Hexane에 依한 米糠蠟油의 抽出에 關한 理論的 硏究

任洪彬 충남대학교 공업기술개발연구소 1976 工業技術開發硏究所論文集 Vol.3 No.2

The effect of extraction of rice bran wax oil withn-Hexane was investigated theoretically. Then the accuracy of the experimental data were compared that of theory by the Hirata, Campbell, Hand and Treybal plot. From this comparision, the following were concluded. At the range of solvent ration 2∼6, the experimental data were regarded correct, but below the solvent ratio 1 and above the solvent ratio 7, the experimental data were considered very incorrect. Calculating the selectivity of the extraction about different solvent ratio, the following were concluded. In the extraction of rice bran wax oil with n-Hexane, the effect of extraction for the separation of wax is more effective than that for the separation of oil.

에이즈 환자의 거대세포바이러스 감염증

김홍빈,박상원,김남중,최희정,신동현,오명돈,김우호,정흠,최강원 대한감염학회 1998 감염 Vol.30 No.4

배 경 : 거대세포바이러스 감염은 인간면역부전바이러스 (Human Immunodeficiency Virus, HIV) 감염자에서 발생하는 가장 중요한 기회감염증의 하나이다. 특히, 국내에서는 95%이상의 국민이 거대세포바이러스의 1차감염을 경험한 상태이므로 에이즈 환자에서 거대세포바이러스 질환의 빈도가 높을 것으로 예상된다. 대상 및 방법 : 1987년 10월부터 1996년 9월까지 서울대학교 병원에서 추적 관찰하였던 128명의 HIV 감염자를 대상으로 하였다. 이들 환자의 의무 기록에서 임상 자료를 얻었다. 거대세포바이러스 망막염은 안과 전문의의 임상적인 소견으로 진단하였으며, 위장관 등 망막이외 부위의 거대세포마이러스 질환은 조직학적으로 확인된 경우에 한하였다. 결 과 : 대상환자 128명의 추적관찰기간은 중앙값이 6(0∼59)개월 이었으며 7명 (5.4%)에서 거대세포바이러스 질환이 발생하였다. 거대세포바이러스 질환은 망막염이 6예, 식도염이 2예, 대장염이 1예, 폐렴 및 부신감염이 1예, 범발성 감염이 1예였다. 거대세포바이러스 질환의 발생빈도는 CD4+ 림프구 수가 적을수록 높았으며, CD4+ 수가 200/㎣미만인 환자 중 15% (6/33)에서 거대세포바이러스 질환이 확인되었다. 11예 중 9예를 ganciclovir로 치료하였으며 이중 7예에서 호전 또는 진행의 억제가 확인되었다. 추적관찰이 가능한 6예 중 3예 (50%)에서 재발하였다. 결 론 : 국내 에이즈 환자에서 거대세포바이러스 질환은 비교적 흔한 기회감염증이다. Background : Cytomegalovirus (CMV) infection is one of the important opportunistic infections in immunocompromised patients. In Korea, seroprevalence of IgG against CMV is over 95%. Therefore, CMV diseases are expected to be a prevalent opportunistic infection in AIDS patients. in Korea. Methods : We reviewed the medical records of 128 patients with HIV infection who visited the Seoul National University Hospital during the period from Nov. 1987 TO Sep. 1996. All the patients were examined by one ophthalmologist and the diagnosis of CMV retinitis were made by funduscopic findings. Other CMV diseases were diagnosed when histopathologic examinations showed the characteristic cytomegalic cells. Results : Median duratior, of follow-up was 8 months. Eleven CMV diseases were found in 7 patients (5.4%): 6 patients ahd retinitis, 2 esophagitis, 1 colitis, 1 pneumonitis, and one patient developed disseminated infection. Fifteen percent (6/33) of the patients whose CD4+ lymphocyte counts were less than 200/㎣ at baseline developed CMV diseases. Out of the 9 cases treated with ganciclovir, 7 improved or were stabilized. No patient received maintenance treatment and 3 had relapsed. Conclusion : CMV diseases are common opportunistic infections in AIDS patients in Korea.

大學 自然系科目 敎授方法에 관한 硏究

任洪彬,金澤基,金振淳,盧泰天 충남대학교 공업교육연구소 1984 論文集 Vol.7 No.1

In order to find the effective teaching method of the natural science subjects in the university level, the project method wsa applied to the actual university classes as a experimental basis. The experimented subjects were "Teaching Method in the Industrial Education"of 3 classes, and "Manufacturing Practices"of 2 classes. The findings of this study are summarized as follows; 1. The project method gives the students much learing motivations and cooperative working habits. 2. The project method gives the students problem solving abilities through creativity and thinking power. 3. The project method is better than the course method in terms of learning content understanding and time utilization of the students. 4. The projet method is not suitable to the class which has a large number of students. 5. The problem level of project should be fitted to the time duration and the level of student' s ability. 6. The more studies are needed in order to generalize the project method to the other subjects.

NP-竝列의 {와/과}에 대하여

任洪彬 서울대학교 교양과정부 1972 論文集 Vol.4 No.-

生成方法이 國語學에 紹介된 이래 格現象의 解明을 위한 진지한 노력이 행해져 왔음은 주지의 사실이다. 필모어의 格文法의 導入 및 특히 主格重出을 圍繞한 一連의 論難은 이러한 解明에 있어 活力素의 역할을 담당해 온 듯이 보인다. {와/과}는 종래에 흔히 共同格助詞라 불려왔다. 이러한 格助詞로서의 {와/과}에 대하여 根源的인 懐疑를 제기한 분은 金完鎭 敎授(1970)이다. 金敎授는 {와/과}를 格機能에서 완전히 분리하여 「並列」의 기능에만 限定시켰으며, 이를 「句接續」의 ‘와’와 「文接續」의 ‘와’로 구분하였다. 이어 李鴻培는 金敎授와의 討論 및 發表에서 이를 格助詞로서의 {와/과}와 「文接續」의 기능으로서의 {와/과}로 분리하여 설명하였다. 두 분의 論議에서는 {와/과}에 관한 한 거의 모든 問題點이 제시 설명된 느낌이 짙다. 그러나 두 분 見解의 相違點은 여전히 남아 있으며, 또 {와/과}에는 아직도 釋明을 필요로 하는 많은 未解決點 및 疑問點들이 남아 있는 듯이 보인다. 筆者는 두 분의 論議에서 啓示된 바 적지 않다. 이를 토대로 하여 筆者는 筆者의 論理가 허용하는 범위 안에서 {와/과}에 關聯한 疑問點들을 統一性있게 밝혀 보려고 한다.

어트랙터 해석을 이용한 AISI 304강 열화 신호의 카오스성 평가

고준빈,오상균,김홍배,이성구,이영호 韓國工作機械學會 2000 한국생산제조학회지 Vol.9 No.2

This study proposes the analysis and evaluation method of time series ultrasonic signal using the chaotic feature extraction for degradation extent. Features extracted from time series data using the chaotic time series signal analyze quantitatively material degradation extent. For this purpose, analysis objective, in this study, is fractal dimension, lyapunov exponent and strange attractor on hyperspace. The lyapunov exponent is a measure of the rate at which nearby trajectories in phase space diverge. Chaotic trajectories have at least one positive lyapunov exponent. The fractal dimension appears as a metric space such as the phase space trajectory of a dynamical system. In experiment, fractal(correlation) dimensions and lyapunov exponents showed values of mean 3.837∼4.211 and 0.054∼0.078 in case of degradation material. The proposed chaotic feature extraction in this study can enhances ultrasonic pattern recognition results from degradation signals.

서울 21세기 : 변화의 관리와 환경학의 역할

강홍빈 서울大學校 環境大學院 1993 環境論叢 Vol.31 No.-

항생제 사용과 관련된 Clostridium difficile 감염증

김홍빈,김남중,최희정,오명돈,김의종,최강원 대한화학요법학회 1997 대한화학요법학회지 Vol.15 No.1

목적 : Clostridium difficile 감염증은 중요한 원내 감염중의 하나로 최근 들어 항균제 사용의 증가와 함께 그 빈도가 늘어나고 있어 Clostridium difficile 감염의 빈도 및 임상양상을 알기 위해 본 연구를 시행하였다. 방법 : 102명의 정상 성인으로부터 대변에서 Clostridium difficile 배양을 시행하였으며, 92년 3월부터 93년 9월까지 서울대학교 병원에 입원한 환자중 대변배양 검사에서 Clostridium difficile이 배양된 61명의 환자를 대상으로 병록지를 토대로 조사하였다. 결과 : 정상 성인 중 3%에서 Clostridium difficile이 분리되었다. 대상환자의 기저 질환은 악성고형종양(29%), 혈액종양(6.5%), 뇌혈관 질환(6.5%), 간경변(4.9%) 등의 순이었으며, 대상 환자의 75%에서 균이 분리되기 6주 이내에 항균제가 사용되었다. 사용된 항균제는 aminoglycoside(60.8%), 1세대 cephalosporin(56.5%), 3 세대 cephalosporin(43.4%), ampicillin(15.2%), metronidazole(15.2%), clindamycin(8.6%)의 순이었다. 흔한 증상은 설사(77%), 복통(53.8%), 오심(37%), 빈맥(25%) 등이었며, 혈액 검사상 백혈구증가증은 21.6%, 저알부민혈증은 3.03%에서 관찰되었다. 44명의 환자중 24명의 환자가 대증적 치료 후 호전되었고, vancomycin이나 metronidazole을 투여받은 17명의 환자중 15명의 환자가 증상의 호전을 보였다. 4예가 사망하였으며, 3예(4.9%)는 재발하였다. 결론 : Clostridium difficile 장염은 항균제 사용시 흔히 발생하는 질환이다. 정상 성인의 3%에서 Clostridium difficile이 분리되었다. Objective : Clostridium difficile gastrointestinal disease is an important nosocomial infection and is associated with antibiotic use. This study evaluated the incidence and clinical characteristics of Clostridium difficile infections. Methods : Stool specimens from 102 normal adults were cultured for Clostridium difficile. Sixty-one patients with Clostridium difficile isolated from stool specimens were reviewed retrospectively. The patients were seen at the Seoul National University Hospital during the period from Mar., 1592 to Sep., 1993. Results : Clostridium difficile was isolated in 3% (3/102) of normal adult Population. Underlying diseases of the patients included solid tumor(29%), hematologic malignancy(6.5%), corebrovascular disease(6.5%), and liver cirrhosis(4.9%). Antibiotics associated with Clostridium difficile infections included aminoglycosides (60.8%), first generation cephalosporin(56.5%), third generation cephalosporin(43.4%), ampicillin(15.2%), metronidazole(15.2%), and clindamycin(8.6%). In 3/4 of the cases, these antibiotics had beer) administered within 6 weeks before Clostridium difficile isolated. Associated symptoms included diarrhea(77%), abdominal pain(53.8%), nausea(37%), fever(37.7%), and tachycardia(25%). Leukocytosis and hypealbuminemia were observed in 21.6% and 30.3%. Out of 44 cases received symptomatic treatment, 54% (24/44) improved. Of 17 cases treated with metronidazole or vancomycin, 88% (15/17) improved. Four cases expired and 3 cases(4.9%)were relapsed. Conclusion : Clostridium difficile gastroenteritis is frequently associated with antibiotic treatment. Three percent of normal adult population had Clostridium difficile.

섬광법을 이용한 박판의 역활산계수 측정에 관한 연구

김홍빈,문찬 順天大學校 1994 論文集 Vol.13 No.1

□A short energy pulse is irradiated on the front surface of thin flat specimen.The resulting temperature-time history of rear surface is recorded and subsequently analyzed to yield the thermal diffusivity by the equation which is derived in idealized and simplified model. It is assumed that the heat flow is one dimensional and the heat pulse is instantaneous and uniform over the entire sample surface. But frequently these conditions are frequently not adequately met. This paper is concerned in the finite pulse- time effect and the aspect ratio effect in partial irradiation on the sample surface.For the finite pulse-time effect, finite pulse width correction factors are calculated by the numerical analyses and compared with the analytic solution. The aspect ratio effects in the partially irradiated specimen are examined by the numerical ananysis of heat conduction equation. The specimen with apect ratio of more than 10 can be considered as one-dimensional specimen.The theoretical equation α=1.37.L²/π²t for the thermal diffusivity with simplified assumptions can be used.