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      • 호산구성 기관지염의 임상적 특징

        김용현,윤여일,임건일,박상준,주재학,김용훈,박춘식 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

        Background: Eosinophilic inflammation of airway is usually associated with airway hyperresponsiveness in bronchial asthma. However, there is a small group of patients who has the eosinophilic inflammation in the bronchial tree with normal spirometry and no evidence of airway hyperresponsiveness, which was named eosinophilic bronchitis. The objectives of this study are 1) to investigate the incidence of eosinophilic bronchitis in the chronic cough syndrome and 2) to evaluate the clinical features and course of eosinophilic bronchitis. Methods : We evaluated 92 patients who had persistent cough for 3 weeks or longer. In addition to usual diagnostic protocol, we performed differential cell count of sputum. Eosinophilic bronchitis was diagnosed when the patient had normal spirometic values, normal peak expiratory flow variability, no airway hyperresponsiveness, and sputum eosinophilia(>3%). Result : The causes of choronic cough were post-nasal drip in 33%, cough variant asthma in 16%, bronchitis in 15%, and eosinophilic bronchitis in 12% of the study subjects. Initial eosinophil percentage in sputum of patience with eosinophilic bronchitis was 26.8±6.1% (3.8-63.7%). Treatment with inhaled steroid is related with a subjective improvement of cough severity and a significant decrease of sputum eosinophil percentage (from 29.1±8.3% to 7.4±3.3%)/ During the follow up period of over ? months, recurrence of cough of was associated with reappearance of sputum eosinophilia. Conclusion : Eosinophilic bronchitis is one of the important causes of chronic cough. Assessment of airway inflammation by sputum examination is important in investigating the cause of chronic cough. Cough in eosinophilic bronchitis are effectively controlled by inhaled corticosteroid, but it recurs frequently over a long term period of follow-up(Korean J Med 60:77-84, 2001)

      • 흉요추부 굴곡-신연 손상에서 척추체의 골절 양상

        고영도,김종오,윤여헌,유재두,정준모 대한골절학회 2003 대한골절학회지 Vol.16 No.2

        목적 : 흉요추부 굴곡-신연 손상에 동반되는 척추체의 골절 양상을 알아 보고자 하였다. 대상 및 방법 : 흉요추부 굴곡 - 신연 손상 21례의 방사선 검사를 검토하여 골절된 척추체의 위치, 전후방 추체 높이, 손상된 분절의 후만각, 척추체 골편의 척추관내 침범 정도 및 척추체의 분쇄 정도를 관찰하였다. 결과 : 총 21례 중 압박 골절이 11례, 방출성 골절이 9례 있었다. 척추체 골절은 85%에서 굴곡-신연 손상된 분절내에서 하부 척추체에 위치하였다. 전방 추체 높이는 평균 27% 감소하였고, 압박 골절이 동반된 경우 18%, 방출성 골절이 동반된 경우 40% 감소하였다. 후방 추체 높이는 평균 1% 감소하였고, 압박 골절이 동반된 경우 1% 증가하였으며, 방출성 골절이 동반된 경우 4% 감소하였다. 손상된 분절의 후만각은 평균 19.5도이었고, 압박 골절이 동반된 경우는 15.4도, 방출성 골절이 동반된 경우는 26.8도이었다. 방출성 골절이 동반된 9례 중 골편의 척추관내 침범은 평균 27%이었으며, 척추체의 분쇄 정도는 71.4%에서 경미하였다, 결론 : 흉요추부 굴곡-신연 손상에서 척추세의 골절은 매우 흔하며 분절내 하부 척추체에 호발하였다. 가해진 힘에 비하여 전후방 추체 높이의 감소, 척추관내 침범 및 분쇄 정도가 적었으며, 이는 굴곡력이나 축성 부하의 효과가 신연력에 의해 일부 상쇄되었기 때문이다. Purpose : To evaluate the configuration of vertebral body fractures in flexion-distraction injuries of thoracolumbar spine. Materials and Method : We investigated the location of fractures, anterior or posterior vertebral body height, kyphotic angle of injured segments, canal encreachment and severity of comminution on radiologic examinations of 21 cases. Result : There were 11 compression fractures and 9 burst fractures. 85% of fractures were located in the inferior vertebrae of injured segments. Anterior vertebral height decreased by 27% on average with decrease of 18% in compression fractures and 40% in burst fractures. Posterior height decreased by 1% on average with increase of 1% in compression fractures and decrease of 4% in burst fractures. The average kyphotic angle of injured segments was 19.5˚ with 15.4˚ in compression fractures and 26.8˚ in burst fractures. The canal encreachment in 9 burst fractures was 27% on average, and the comminution of vertebral body was mild in 74%. Conclusion : The fracture of vertebral body in flexion-distraction injuries of thoracolumbar spine was very common, and located on the inferior vertebare of injured segment. The decrease of vertebral height, canal encreachment and severity of comminution was relatively less than the estimated from mechanism of injury, with offset effect of distraction force.

      • 노령에서 고관절 골절에 영향을 주는 수상전 요인

        김종오,윤여헌,고영도,유재두,정준모,방한천,강규복 대한골절학회 2002 대한골절학회지 Vol.15 No.4

        목 적 : 노령에서 고관절골절의 여러 원인적 요인들과 상관관계를 분석, 그 연관성에 대해 알아 보고자 하였다. 대상 및 방법 : 2001년 1월부터 2002년 5월까지 대퇴 고관절 골절로 본원에서 치료받은 환자중 60세 이상이고 골밀도 검사를 시행받은 158례를 대상으로, 수상전 요인을 나이, 성별, 흡연여부, 비만정도, 골절종류, 수상장소, 다른 이환 질환, 골절전 활동도, 골밀도 검사, 수상당시 바닥의 경도, 수상당시 넘어진 방향, 수상에너지에 따라 대퇴 경부골절과 전자간 골절, 전자간 골절중 안정골절과 불안정 골절로 나눠 비교하였다. 결 과 : 80세 이상의 군에서 대퇴 전자간 골절이 대퇴 경부 골절에 비해 의미있게 많이 발생했음을 알 수 잇었으며(p<0.001) 환자의 수상전 활동정도의 비교에서도 활동정도가 낮았던 군에서 대퇴 전자간 골절이 의미있게 많이 발생하였다(p<0.001). 골밀도 검사에 따른 비교에서는 T-score -3.0 이하인 군에서 대퇴 전자간 골절이 많았으며(p<0.005), 수상에너지에 따른 비교에서는 적은 에너지에 의한 골절이 전자간 골절에서 많았다(p<0.05). 대퇴 전자간 골절은 안정 골절과 비안정 골절로 나눈 비교에서는 사회 활동이 어려운 ADL C이하의 군과(p<0.05), 골밀도 T-score -3.0 이하인군에서는 의미있는 차이를 보였다(p<0.001). 결 론 : 노령에서의 고관절 골절 중 80세 이상의 고령에서, 골밀도 T-score -3.0 이하인 경우, 일상생활 활동정도가 낮은 경우에, 비교적 적은 에너지에 의한 충격시에 대퇴 전자간 골절의 발생이 대퇴 경부 골절에 비해 의미있게 많았고 전자간 골절에서 불안정 골절은 사회활동이 적고 골밀도 T-score -3.0 이하인 경우 많음을 알수 있었다. Purpose : We studied the co-relation on the causes of the hip fracture through the analysis of a relevance on the etiological factors as increased incidence according increasing old age. Materials and Methods : Total 158 cases that treated on the hip fracture from 2001 Jan. to 2002 May were studied. The parameters were age, gender, smoking, obesity, type of fracture, place of fracture, other comorbidity, activity of daily living, bone marrow densitometry, hardness of floor, orientation, injury energy. And then, we analysis of difference between femur neck fracture and femur intretrochanter fracture and between stable femur intertrochanter fracture and unstable femur intertrochanter fracture. Results : The incidence of the femoral intertrochanteric fracture was larger significantly than that of the femoral neck fracture in the older then 80(p<0.001). On the comparison of the pre-fractural activity of daily living, the group revealed lower activity had larger incidence of femoral intertrochateric fracture(p<0.001). Also, the femoral intertrochanteric fracture was more larger osteoporosis patient group(p<0.005), and lower energy trauma(p<0.05). In a unstable femoral intertrochanteric fracture, 21 cases(77.7%) of total 27 cases were belong to the group of the activity of daily living scale below C(p<0.05), 24 cases pf 27 cases were belong to the osteoporosis patient who was estimated below -3.0 on T-score(p<0.001). Conclusion : In the hip fracture of the elderly patients, the femoral intertrochanteric fracture is more prevalance ratherthe femoral neck fracture on the cases of older patient more than 80 year-old, lower activity of daily living scale, lower T-score less than -3.0 on BMD, lower energy trauma. Also, in femur intertrochanter fracture, unstable fracture is more common in low daily activity and owteoporosis.

      • KCI등재후보

        대기오염과 천식증상에 의한 응급실내원과의 연관성에 관한 환자교차연구

        임형준,이상윤,윤기정,주영수,강대희,조수현 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

        Objectives : This study, using case-crossover design, search a relationship between changing levels of air pollutants and asthma attack in asthma patients. Methods : We searched the daily total number of asthmatic patients at hospital's emergency room in Seoul, Korea by investigating total 49 general hospital's emergency room records. Otherwise, We investigated medical records of asthmatic patients at one of the 49 hospitals we have searched. We investigated addresses that they are living, diagnosis, smoking history, whether respiratory infection or not, medications. We analyzed the data by 1:m conditional logistic regression used when matched case-control study is analyzed. Control periods were chosen by bidirectional paired matching technique 7, 14 days before and after case periods. Results : the relative risk of asthmatic attack by 100 ppm ozone increase between June and September were 1.348(95 % CI = 1.010∼1.619). Between November and February, the relative risk by 100 ㎍/㎥ TSP increase, 100ppb sulfur dioxide and nitrogen dioxide were respectively 1,278(1.010∼1.619), 1.237(1.019∼1.502), 1.285(1.006∼1.640). In stratified analysis, the relative risk were significant when the asthmatic patients were children aged 15 years or below, when there were respiratory infection, and when the patients took medications irregularly Conclusions : There was statistically significant association between ambient levels of air pollutants and asthmatic attack. So, we have to exert our efforts to minimize the air pollution effectively, to protect public health from air pollution.

      • KCI등재

        주상골 골절에서 Herbert/Whipple 나사못의 바람직한 위치 : 모형연구 A Model Study

        유재두,김종오,윤여헌,고영도,배서영,이정준 대한골절학회 2002 대한골절학회지 Vol.15 No.4

        목 적 : 주상골 골절 치료에 사용하는 Herbert/Whipple 나사못의 바람직한 삽입 위치를 알아보고자 하였다. 대상 및 방법 : 4개의 사체에서 분리한 주상골을 이용하여 각 주상골마다 12개씩 주물 모형을 제작하여 대상으로 하였다. 각 모형에서 핀 삽입 안내 장치(jig, Zimmer??)를 이용하여 안내핀(guide wire)을 원위부에서 근위부를 향해 삽입하되 원위부에 A, B, C, D의 4개 근위부에 0, 5, 10의 3개의 지점을 설정하여 총 12가지 방법으로 삽입하였다. 각 모형은 주상골의 장축에 직각인 방향으로 근위부, 요부, 원위부의 세 단면을 만들고 핀 삽입의 흔적과 가장 가까운 피질골 표면과의 거리를 측정하여 이 거리가 대적으로 길 때 안전한 것으로 평가 하였다. 결 과 : 핀 삽입의 흔적과 가장 가까운 표면과의 거리가 근위부에서는 D5, 원위부에서는 C10이 유의하게 길었다. 원위 삽입 위치를 기준으로 하였을 때 근위부에서 C가 유의하게 거리가 길었고 요부, 원위부, 그리고 근위 목표 지점을 기준으로 하였을 때의 측정된 거리는 유의한 차이가 없었다. 결 론 : Herbert/Whipple 나사못의 삽입 위치는 근위부 골절에서는 D5군, 원위부 골절에서는 C5군이 가장 바람직한 위치라고 할 수 있엇고 요부 골절에서는 A0군과 D0군을 제외하면 별 다른 차이 없이 비교적 안전하다고 할 수 있다. 바람직한 위치 선정을 위해서는 근위부의 목표지점보다 원위부의 지점을 정확히 하는 것이 중요하다고 사료된다. Purpose : To evaluate optimal placement of the Herbert/Whipple screw in scaphoid fracture Materials and Methods: Forty eight model molded from four cadaver scaphoids were used for this study. Using the Herbert/Whipple jig, the guide wire was placed distal to proximal into each scaphoid with twelve method which were four entry points and three target points. Guide wire placement was then evaluated with three planes in the proximal, middle, distal planes and distance from the nearest cortex. Results : The most concentric position in the proximal plane was D5, in the middle plane C10. As distal entry point, the most concentric position in proximal plane was C. There were no statistical concentric, as middle, distal plane, and proximal entry point, Conclusion : The most ideal placement were D5 in proximal fractures of the scaphoid, C5 in distal fractures. In waist fractures of the scaphoid, there were relatively safe, except A0 and D0. The position of entry points was more important than that of target points for ideal screw placement.

      • KCI등재후보

        사업장 소음 폭로에 의한 일과성 역치 상승과 회복

        조수헌,하미나,한상환,주영수,성주헌,강종원,윤덕로,송동빈,이명학,김선태 大韓産業醫學會 1996 대한직업환경의학회지 Vol.8 No.2

        To determine the recovery time from noise-induced temporary threshold shift(TTS), a prospective field study was conducted at three worksites where workers are known to be exposed high level of noise. Subjects were selected according to answers on a questionnaire which inquired about otological history and previous noise exposure, including avocational, military and occupational exposures. After excluding employee with past otologic problems, recent exposure to high level noise, and under medications, total 92 employees participated in the study. Among 92 participants, complete consecutive audiometric examinations were carried out at 0∼2 hours, 5∼7 hours, 14∼16 hours after worktime noise exposure on 26 participants wearing hearing protectors and 22 participants wearing no protective devices. The difference between the hearing level 0∼2 hours after noise exposure and 5∼7 hours is statistically significant by paired t-test(p<0.01). The median recovery times calculated from the data of 22 participants wearing no protective hearing devices are 15.6 hours at 4000Hz, and 7.7 hours, 10.3 hours, 8.4 hours at 1000Hz, 2000Hz and 8000Hz respectively. These data suggest that when measuring the pure tone audiometry for noise exposed workers, at least 16 hours noise-free interval is required.

      • KCI등재

        Effects of Online Mindful Somatic Psychoeducation Program on Mental Health During the COVID-19

        Young Sook Yook,Jae-Hon Lee,Inkyoung Park,Hwi-young Cho 대한신경정신의학회 2024 PSYCHIATRY INVESTIGATION Vol.21 No.1

        Objective This study aims to determine the effects of online mindful somatic psychoeducation program (o-MSP) on mental health in female university students during the coronavirus disease-2019 (COVID-19).Methods Thirty-eight female university students were randomly assigned to an intervention group (IG, n=19) or a control group (CG, n=19). IG received o-MSP for 2-hours per session, twice weekly for 4-weeks; CG maintained their usual daily routine for 4-weeks. Measurements were performed pre- and post-intervention to assess stress, anxiety, and social connectedness using Perceived Stress Scale, State-Trait Anxiety Inventory, and Social Connectedness Scale. A qualitative analysis of changes in soma and social connectedness, subjectification of the soma, and mind–body integration was conducted through online interviews.Results Regarding stress and social connectedness, there were no significant difference between the groups (p>0.05). However, significant differences were observed in the main effect of time of measurement and time×group interaction, with IG showing significant improvement post-intervention, unlike CG (p<0.05). Regarding anxiety, there were significant differences in the main effect of time of measurement, time×group interaction, and group factor (p<0.05). Post-intervention, CG did not show a significant change, while IG showed a significant decrease (p<0.05). Qualitative analysis revealed that participants experienced “changes in soma and social connectedness,” “subjectification of soma–body,” and “embodiment of mind–body integration,” and reported improved mental health.Conclusion The o-MSP effectively reduced stress and anxiety in female university students and improved social connectedness. This suggests that o-MSP can be used to manage the mental health of university students in various settings.

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