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沼田浩通 ( Numata¸ Hiromichi ) 한국일어교육학회 2021 일본어교육연구 Vol.- No.56
これまで、付帯状況を表わす「姿勢変化動詞+ナガラ」のアスペクト的意味は〈結果の継続〉になると説明されることが多かった。しかし、実例を調査してみると、数は少ないものの〈動作の継続〉を表す用例も確認できる。本稿は、同じ「姿勢変化動詞+ナガラ」の構文であっても、ナガラ節が異なるアスペクトを表す用例に注目し、「姿勢変化動詞+ナガラ」の用例をナガラ節のアスペクトの違いによって分類することで、ナガラ節のアスペクトとナガラ節が表す意味との関連性について考察したものである。 その結果、「姿勢変化動詞+ナガラ」の用例をナガラ節のアスペクトが<動作の継続>を表すもの、〈結果の継続〉を表すもの、<反復相>を表すものの3種に分類できた。このうち、アスペクトが〈動作の継続〉であるナガラ節は主節の出来事と同時並行的な主体の姿勢の変化を表わし、〈結果の継続〉であるナガラ節は主節の出来事が実現する過程で主体がとっている姿勢を表わす。また、〈反復相〉の場合、ナガラ節は主節の出来事と同時並行的に反復して行われる主体の姿勢の変化をひとまとまりに捉えることを確認した。 重要なのは、主節の出来事がナガラ節の出来事の運動過程を時間的に超えずに実現する場合、「姿勢変化動詞+ナガラ」は従来なされてきた説明とは異なり、〈動作の継続〉を表わすことができることが確認できたことである。このことは、ナガラという接続形式は“動作動詞=動作の継続、変化動詞=結果の継続”という二分法の動詞分類では捉えることができない、姿勢変化動詞が表わす出来事の〈運動〉局面に焦点を当てることができることを示している。 Previous studies have suggested that the 'postural change verb + nagara' representing collateral circumstances indicates the “resultative” aspect. However, some case studies have shown that there are a few examples where the postural change verb + nagara construction indicates the “progressive” aspect. Noting the examples where some nagara clauses indicate different aspects even if they have the same construction of postural change verb + nagara, this paper is to classify these examples of postural change verb + nagara construction according to the differences in aspects and study the relationship between the aspect and meaning of nagara clause. According to the study findings, the aspects of nagara clauses in examples containing postural change verb + nagara constructions could be classified into three: progressive, resultative and iterative. Among them, while the nagara clause whose aspect was progressive indicated the postural change of an agent running parallel with the event of the principal clause, the nagara clause whose aspect was resultative indicated a posture taken by the agent while the event of the principal clause was realized. Likewise, in case of iterative aspect, the nagara clause comprehensively indicated the postural change of an agent repeatedly performed along with the event of the principal clause. More importantly, it was confirmed that if the time interval for the event of a principal clause is shorter than that for the event of the nagara clause, the postural change verb + nagara can indicate the “progressive” aspect unlike the previous explanations. It means that the conjunction forms of nagara can be focused on the ‘action’ stage of an event indicated by a postural change verb which cannot be understood in the dichotomous classification of verbs where they are verbs of action and verbs of change.
파랑중 KCS 선형의 2자유도 운동에 관한 CFD 시뮬레이션
Hiromichi Akimoto,박종천(Jong-Chun Park),옥유빈(Yu-Bin Ock),허재경(Jae-Kyung Heo),정세민(Se-Min Jeong),Rahaman Md. Mashiur,김현철(Hyun-Chul Kim) 대한조선학회 2012 대한조선학회 학술대회자료집 Vol.2012 No.5
A unsteady RaNS code is applied to simulate MOERI container ship model, KCS, in regular head sea conditions. Various combinations of Froude's number, wave length and wave height are simulated. With respect to the integral quantities, a comparison between simulation and experimental results shows that the computed amplitude of heave and pitch motions are in well agreement each other. However, the first-order harmonic amplitudes of heave are significantly under predicted by the present simulations.
Novel Approaches for High Power and High Speed IGBTs
Hiromichi Ohashi,Akio Nakagawa 전력전자학회 1989 ICPE(ISPE)논문집 Vol.- No.-
New approaches for high power IGBTs such as (1) self-aligned deep P-diffusl on, (2)Stripe gate source pattern, (3)Hole bypass structure, (4) Silicon wafer Direct Bonding technique and (5)Donble gate structure for lateral IGBTs are reviewed. All of these novel aporoaches make possible high power handling capability with high speed and ruggedness against SOA. These excellent IGBT feature satisfy Increasing demands for high frequency power conversion and power IC applications.
A Capable High-Throughput Technology Generates Low Molecular-Weight Leads for Pharmaceuticals
Hiromichi Kotaki 가톨릭의과학연구원 2000 가톨릭 의과학연구원 국제학술대회 Vol.4 No.-
To win the way to the finals in the recent competitive environment of the drug-discovery research, it is demanded for one to collect a larger number of and a greater variety of 'drug-like' samples, screen them within a shorter period of time and then identify more promising lead compounds quickly. The expectation that robotics and miniaturization of assays can expand the capability of random screening of low molecular-weight chemical compounds and natural products has been realized. High-throughput screening(HTS) utilizing robotic systems allows for rapid and efficient identification of lead candidates from al huge number of samples in mega-pharmaceutical companies.
Biological Activities of Non - saponin Compounds Isolated from Korean Red Ginseng
(Hiromichi Okuda),(Sung Dong Lee),(Yukinaga Matsuura),(Yinan Zheng),(Keizo Sekiya),(Takeshi Takaku),(Kenji Kameda),(Kumi Hirose),(Kazuhiro Ohtani),(Osamu Tanaka),(Toshiie Sakata) 고려인삼학회 1990 Proceedings of International Symposium on Korean G Vol.- No.-
Stem cell-based therapy for inflammatory bowel disease
Hiromichi Shimizu,Kohei Suzuki,Mamoru Watanabe,Ryuichi Okamoto 대한장연구학회 2019 Intestinal Research Vol.17 No.3
Inflammatory bowel disease (IBD) is an idiopathic, multi-etiological disease characterized by inflammation and mucosal destruction of the gastrointestinal tract. Despite the remarkable advance in immunomodulating therapies, there still remains a certain population of patients who are refractory to conventional as well as biologic therapies and fail to achieve mucosal healing. To improve the prognosis of those patients, at least 2 types of stem cells have been tested for their potential therapeutic use. Transplantation of hematopoietic stem cells or mesenchymal stem cells have been tested in several clinical studies, but their beneficial effect still remains controversial. In this review, we would like to overview the recent clinical challenges of stem cell-based therapies in IBD and also introduce our new therapeutic plan of intestinal stem cell transplantation for IBD, based on our ex vivo intestinal organoid culture technique.
Rapid prediction of 1-year efficacy of tofacitinib for treating refractory ulcerative colitis
( Hiromichi Shimizu ),( Toshimitsu Fujii ),( Shuji Hibiya ),( Maiko Motobayashi ),( Kohei Suzuki ),( Kento Takenaka ),( Eiko Saito ),( Masakazu Nagahori ),( Kazuo Ohtsuka ),( Mamoru Watanabe ) 대한장연구학회 2021 Intestinal Research Vol.19 No.1