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Hien-Trung Trinh,Eun-Ah Bae,Myung Joo Han,Yong-Wook Shin,Dong-Hyun Kim 고려인삼학회 2007 Journal of Ginseng Research Vol.31 No.3
To evaluate the antiatopic effect of Korea Red Ginseng (RG, steamed root of Panax ginseng C.A. Meyer, Family Araliaceae), its inhibitory effect on passive cutaneous anaphylaxis reaction and itching in mice was measured. RG and its ingredient saponin fraction (SF) potently inhibited passive cutaneous anaphylaxis (PCA) reaction and scratching behaviors. RG at a dose of 100 ㎎/㎏ and SF at a dose of 50 ㎎/㎏ significantly inhibited the scratching frequency by 32% and 38%, respectively. RG and SF also inhibited the degranulation and protein expression of tumor necrosis factor (TNF)-α and interleukin (IL)-4 of RBL-2H3 cells induced by IgE-antign complex. However, polysaccharide fraction of RG did not inhibit it. Based on these findings, RG can improve allergic skin disorders atopic dermatitis and contact dermatitis by the regulation of TNF-α, and IL-4 produced by mast cells and basophils and their membrane stabilization.
Trung Tran,Loc Thi My Nguyen,Thanh Thi Nghiem,Hien Thi Thu Le,Cuong Huu Nguyen,Thuy Phuong La,Trung Tien Nguyen,Hang Thi-Thu Nguyen 한국과학학술지편집인협의회 2019 Science Editing Vol.6 No.2
This study aimed at elucidating the present situation of scholarly journals published in Vietnam according to the minimum criteria to be indexed in the ASEAN Citation Index (ACI) and Scopus, with the goal of suggesting development strategies for scholarly journals in Vietnam. From the 387 journals accredited by the Vietnamese State Council for Professorship, 13 education journals were arbitrarily selected, and their compliance with the five minimum criteria for the ACI (peer review, timeliness, abstracts in English, references in Roman script, and a website in English) and the six minimum criteria for Scopus (peer review, timeline, abstracts in English, references in Roman characters, Electronic International Standard Serial Number [ISSN], and publication ethics) were assessed. Two of the 13 journals were eligible to be indexed in the ACI, while none fulfilled the minimum criteria to be indexed in Scopus. An urgent task for the editors of those journals is to establish an informative journal homepage in English that provides basic information on the journal. Then, an Electronic ISSN can be obtained from the ISSN International Center. Furthermore, the following steps are suggested for journal promotion: establishment of appropriate editorial policies and publication ethics procedures, improvement of research integrity, enhancement of the journals’ reputation in the international scientific community, and improvement of the online publishing system by adopting a journal manuscript management system. To achieve those goals, financial support from the Vietnamese government will be invaluable.
Hien-Trung Trinh,Eun-Ah Bae,Jung Joon Lee,Dong-Hyun Kim 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.12
To understand anti-allergic effect of Curcuma aromatica (family Zingerberaceae), which inhibited passive cutenous anaphylaxis (PCA) reaction in preliminary study, we isolated its main constituents, curcumin, demethoxycurcumin and bisdemethoxycurcumin, and investigated their inhibitory effects against PCA reaction and scratching behavior. These curcuminoids inhibited the PCA reaction induced by the IgE-antigen complex (IAC) and the scratching behavior induced by compound 48/80. These curcuminoids also inhibited degranulation, protein expression of TNF-α and IL-4, and transcription factor NF-κB activation in IAC-induced RBL-2H3 cells. Of these curcuminoids, curcumin exhibited the most potent inhibition, followed by demethoxycurcumin and bisdemethoxycurcumin. These findings suggest that curcuminoids, particularly curcumin, can improve the symptoms of allergic diseases, such as anaphylaxis and itching.
Trinh, Hien-Trung,Bae, Eun-Ah,Han, Myung-Joo,Shin, Yong-Wook,Kim, Dong-Hyun The Korean Society of Ginseng 2007 Journal of Ginseng Research Vol.31 No.3
To evaluate the antiatopic effect of Korea Red Ginseng (RG, steamed root of Panax ginseng C.A. Meyer, Family Araliaceae), its inhibitory effect on passive cutaneous anaphylaxis reaction and itching in mice was measured. RG and its ingredient saponin fraction (SF) potently inhibited passive cutaneous anaphylaxis (PCA) reaction and scratching behaviors. RG at a dose of 100 mg/kg and SF at a dose of 50 mg/kg significantly inhibited the scratching frequency by 32% and 38%, respectively. RG and SF also inhibited the degranulation and protein expression of tumor necrosis factor $(TNF)-{\alpha}$ and interleukin (IL)-4 of RBL-2H3 cells induced by IgE-antign complex. However, polysaccharide fraction of RG did not inhibit it. Based on these findings, RG can improve allergic skin disorders atopic dermatitis and contact dermatitis by the regulation of $TNF-{\alpha}$, and IL-4 produced by mast cells and basophils and their membrane stabilization.
Hien, Nguyen Khoa,Bao, Nguyen Chi,Ai Nhung, Nguyen Thi,Trung, Nguyen Tien,Nam, Pham Cam,Duong, Tran,Kim, Jong Seung,Quang, Duong Tuan Elsevier 2015 Dyes and pigments Vol.116 No.-
<P><B>Abstract</B></P> <P>A fluorescent chemosensor based on dimethylaminocinnamaldehyde-aminothiourea (DA) has been designed, synthesized, and applied with a combined theoretical and experimental study. The synthetic path, optimized molecular structure and characteristics of DA were carried out using the calculations at the B3LYP/LanL2DZ level of theory. The experimental investigations have a good agreement with the theoretical results. DA can be used as a chemosensor for simultaneous quantification of silver, copper, and mercury ions in aqueous solution at the ppb level. The stable geometric structures of the complexes between DA and Ag<SUP>+</SUP>, Hg<SUP>2+</SUP>, Cu<SUP>2+</SUP> with stoichiometry of 1:1, 2:1, and 2:1, have been found and investigated for electronic properties and fluorescence quenching phenomena by using Atoms in Molecules (AIM) and Natural Bond Orbitals (NBO) analyses.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A chemosensor has been studied with a combined theoretical and experimental study. </LI> <LI> Suitable for detecting trace amounts of Ag(I), Hg(II), Cu(II) ions at the ppb concentration level. </LI> <LI> High water solubility, simplicity, rapid analysis time, wide range of pH. </LI> <LI> The stable geometric structures of the complexes have been found and investigated. </LI> <LI> The fluorescence quenching of complexes is studied by using AIM and NBO analyses. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>