한국인에서 도파민 D4 수용체 다형성과 Novelty Seeking 성격 특성의 연관성

이헌정,이홍석,강화연,김린,이민수,서광윤,변영찬 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.4

연구목적 : 저자들은 한국인에서 도파민 D4 수용체(DRD4) 유전자의 다형성과 성격의 관련성을 알아보고자 본 연구를 시행하였다. 방 법 : 173명의 건강한 한국인 여자 청소년(13.88±0.29세)을 대상으로 하여 성격 기질 설문지(Temperament and Character Inventory : TCI)를 작성하도록 하였으며, 이들에서 DRD4 exon Ⅲ 48-bp VNTR(variable numbers of tandem repeats) 다형성을 분석하였다. 결 과 : DRD4 exon Ⅲ Vntr에서 긴 대립유전자(≥5 repeats)를 가진 군이 긴 대립유전자를 가지지 않은군에 비하여 Novelty Seeking 척도 점수가 유의하게 높았다(t=2.11,p=0.037). 결 론 : 본 연구 결과는 DRD4-exon Ⅲ의 긴 대립유전자가 Novelty Seeking 성격과 관련이 있다는 기존의 외국에서의 연구결과를 다시금 확인해주는 것이다. Objectives : We investigated the relationship of personality traits with dopamine D4 receptor(DRD4) exon Ⅲ polymorphism in a Korean population. Methods : We analysed DRD4 exon Ⅲ 48-bp repeats polymorphism in 173 Korean heakthy female adolescents(age=13.88±0.29years) who also completed Temperament and Charater Inventory(TCI). Results : Novelty seeking score of the TCI was significantly higher in the subjects with DRD4 long alleles(≥5 repeats) compares with the subjects without these (t=2.11, p=0.037). Conclusion : The present study supports the previous reports that long repeats of the DRD4-exon Ⅲ polymorphism are relatedwith Novelty Seeking personality.

일본의 정수처리 기술개발 최신동향 : e-Water'를 중심으로 e-Water Project

이석헌 대한상하수도학회 2003 상하수도학회지 Vol.17 No.5

운동조절이론과 중추신경계 손상환자를 위한 치료 접근법의 재검토

김종만,신헌석 한국전문물리치료학회 2001 한국전문물리치료학회지 Vol.8 No.1

Physical therapists should understand motor control models and apply various models to evaluation and treatment of neurologically impaired patients, Thus, this paper reviews motor control models and applications in clinical settings. Assumptions and limitations of reflex models, hierarchical models, and systems models are presented. This paper also delineates goals and dissatisfaction of neurologic rehabilitation approaches for neurologically impaired patients. Muscle reeducation approach, neurotherapeutic facilitation approach, and contemporary task-oriented approach are explained.

하퇴 의지 사용자의 족저압 분포 특성에 관한 연구

김장환,신헌석 한국전문물리치료학회 2001 한국전문물리치료학회지 Vol.8 No.3

The purpose of this study was to compare the static pressure, dynamic pressure, dynamic pressure-time integral, relative impulse, and contact time between the sound lower limb and amputated lower limb in trans-tibial amputee subjects using Parotec system. Seventeen trans-tibial amputee subjects wearing endoskeletal trans-tibial prosthesis voluntarily participated in this study. The results were as follows: 1) In static standing condition, there were significantly higher static pressure in sound lower limb insole sensor of 10, 14, 15, 18, 19, 23, and 24 and in amputated lower limb insole sensor of 9, 12, and 16 (p<.05). 2) In dynamic gait condition, there were significantly higher dynamic pressure in sound lower limb insole sensor of 2, 18, 22, 23, and 24 and in amputated lower limb insole sensor of 5, 9, 10, 11, 12, 14, 15, and 16 (p<.05), 3) In dynamic gait condition, there were significantly higher pressure-time integral in sound lower limb insole sensor of 2, 4, 18, 19, 20, 21, 23, and 24 and in amputated lower limb insole sensor of 5, 11, 12, and 15 (p<.05). 4) In dynamic gait condition, there were significantly higher relative impulse in sound lower limb insole sensor of 18, 19, 20, 22, 23, and 24 and in amputated lower limb insole sensor of 5, 9, 10, 11, 12, and 15 (p<.05). 5) In dynamic gait condition, there was significantly higher percentage of contact time in push off phase of sound lower limb and in support phase of amputated lower limb (p<.05). These results suggest that trans-tibial amputee subjects had characteristics of shortened push off phase due to unutilized forefoot and of lengthened support Phase with higher pressure in the midfoot.

호기성 SBR공정에 의한 비이온성 계면활성제 NPEO 의 제거

범진영,이석헌 대한상하수도학회 2002 상하수도학회지 Vol.16 No.5

Removal of non-ionic surfactant, nonylphenol ethoxylate (NPEO), by aerobic sequencing batch reactor was investigated using lab scale experimental apparatus. Bio-degradation of NPEO resulted in ethoxylate chain shortening and nonylphenol (NP) production. About 5mg/L of NPEO was introduced and only < 0.09mg/L of NPEO and NP was detected in treated effluent. During the aeration, NPEO and NP in mixed liquor were also reduced. Most of NP and short-chained NPEO were detected in solid phase. Anaerobic condition provided during settling of sludge and decanting of treated effluent caused increase of NP in sludge.

나노여과 공정에의한 플라스틱첨가제 및 내분비계교란물질의 제거특성

오정익,이석헌 경희대학교 2003 環境硏究 論文集 Vol.12 No.-

The rejection characteristics of sanofiltratios membranes for plastic additives and for endocrine disruptors were investigated. Bisphenol A, estradiow, phtawic acid estEus, phosphoric acid tri-esters, and so on wereused as target solutes. a simplified diffusion convection model was proposed to neglect the effect of the operating pressures and the rejections were converted into one parametEu. The converted rejection parametEu was further separated into two parameters of the size effect parametEu and the parameter of other effects. this separation into two parametEus was successful and the characteristics of the other factors were discussed. the difference is tho material of membranes affected the parametEus and similar membranes gave similar tesdoscy of the parameter.

자외선/과산화수소 고도산화공정에 의한 하수 2차 처리수 중의 용존유기물 분해에 미치는 부유물질과 과산화수소 농도의 영향

안규홍,이석헌,안석,김기팔,정민우,맹승규 대한상하수도학회 2002 상하수도학회지 Vol.16 No.3

Secondary effluent of activated sludge process was treated by UV/H_2O_2 advanced oxidation process to investigate the effect of suspended matter and H_2O_2 concentration. With low dosage of UV radiation, the concentration of the dissolved organic compounds measured as DOC could be increased with and without hydrogen peroxide. It was suggested that the cause of DOC increase in treated samples was the decomposition of suspended microbial particles and the incomplete oxidation of dissolved organic compounds. The removal of suspended solid significantly enhanced the degradation of DOC in both UV and catalyzed UV oxidation. Color and odor of secondary effluent was effectively removed. Turbidity was decreased by oxidation and the particle size distribution was shifted to lower range. With increased H_2O_2 dosage (30∼120mg/l), the removal of DOC was enhanced. To obtain the required quality meeting the regulated level for water reuse, additional treatment for turbidity rejection was required.

유지-이완기법과 냉치료가 지연성 근육통에 미치는 효과

김종만,박장성,김원호,신헌석,김연중 한국전문물리치료학회 2000 한국전문물리치료학회지 Vol.7 No.1

Despite research to treat delayed onse muscle soreness(DOMS), no effective treatment has been reported. The purpose of this study is to investigate the effect of a hold-relax technique and cryotherapy on DOMS. Thirty-three subjects were randomly assigned to one of three treatment groups: control, hold-relax technique, or hold-relax technique and cryotherapy. DOMS was induced in the non-dominant biceps muscle through repeated eccentric contractions. Resting elbow joint position, flexion and extension(universal goniometer), pain(Visual Analogue Scale; VAS), and WBC count(blood analysis) were measured one hour before DOMS was induced and 24, 48, and 72 hours after DOMS was induced. The data were analyzed by repeated measure of two-way ANOVA. The results of this study were summarized as follows: 1) While analysis showed no significant differences between groups in relation to resting elbow joint position, there were significant differences over time, especially at 24, 48 hours after DOMS was induced compared with resting elbow joint position before DOMS was induced. 2) While analysis showed no significant differences between groups in relation to range of flexion, there were significant differences between rage of flexion before DOMS was induced and range of flexion 72 hours after DOMS was induced. 2) There were no significant differences between groups or over time in relation to range of extension. 4) While analysis showed no significant differences between groups in relation to VAS, there were significant differences over time in different hours. 5) There were no significant differences between groups or over time in relation to WBC count. 6) There were no interactions between groups or over time in all variables. This results suggested that hold-relax technique and cryotherapy were not effective to reduce DOMS.

The Rejection of Turbidity , Dissolved Matter and Bacteria by MF Process

Seock Heon Lee 대한환경공학회 1998 Environmental Engineering Research Vol.3 No.4

Effects of Lumbar Stabilization on the Trunk and Lower Limb Muscle Activity and Velocity of the Center of Pressure During Single Leg Standing

Heon-seock Cynn 한국전문물리치료학회 2010 한국전문물리치료학회지 Vol.17 No.4

The aim of this study was to investigate the effects of lumbar stabilization on both trunk and lower limb muscle activity and center of pressure (COP) in single leg standing. Surface electromyography (EMG) was used to collect muscle activity data, the mean velocity of COP was measured using a force plate, and a pressure biofeedback unit was used for lumbar stabilization training. The findings of this study are summarized as follows: l) The EMG activity of the erector spinae decreased significantly and the activity of the rectus abdominis, internal oblique, external oblique, gluteus maximus, and gluteus medius increased significantly with lumbar stabilization single leg standing. 2) No differences in activity in the tibialis ante-rior, medial gastrocnemius, rectus femoris, and medial hamstrings were found with single leg standing. 3) The mean velocity of COP in the antero-posterior and medio-lateral directions in the lumbar stabilization single leg standing decreased significantly compared with the preferred single leg standing. The findings of this study therefore indicate that lumbar stabilization can facilitate the co-activation of deep stabilization and global muscles that improve postural control capability during single leg standing.