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      • KCI등재

        Saturation improvement in hue-preserving color image enhancement without gamut problem

        Hengjun Yu,Kohei Inoue,Kenji Hara,Kiichi Urahama 한국통신학회 2018 ICT Express Vol.4 No.3

        This study proposes a method to improve the saturation of colors during hue-preserving color image enhancement without the gamut problem. First, the color of each pixel in an input image is projected onto one of three bisecting planes or bisectors of an RGB color cube to increase saturation. Then, that projected color is transformed into a target color with a designated luminance and the same hue as the original color. Experimental results show that the proposed method can enhance color images better than can recent hue-preserving color image enhancement methods.

      • Wireless Remote Water Meter Design of Automatic Meter Reading System

        Zhu HengJun,Zhu YiSheng 보안공학연구지원센터 2015 International Journal of Smart Home Vol.9 No.12

        By wireless communication through GPRS internet, a remote water metering system with low cost, accuracy and adaptable to complex environment was designed. In this paper, the analysis on the scheme confirmation, the development of management software was carried out, and the integrated design of the system based on GPRS was studied. The general planning and the technical requirements on the user’s water consumption detecting system was also put forward, based on the S3C2440 chip.

      • A design and Implementation of Portable Spectrum Analyzer

        Zhu Hengjun,Wang Wenxing 보안공학연구지원센터 2015 International Journal of Multimedia and Ubiquitous Vol.10 No.12

        With the progress of society signal measurement and analysis have more widely range of applications, but the spectrum analyzer was generally expensive to make it difficult for popularization and application. In this paper, a design methodology of low cost, stable reliable spectrum analyzer based on the idea of Software Defined Radio (SDR) is presented, which consists of three functional units. The STM32 is the core of spectrum analyzer and is the key base to signal acquisition and analysis of the system. This paper designs the detailed hardware circuit and the software and optimizes the display program to obtain a higher refresh rate. Through testing the design is stable and reliable, simple and practical, and suitable for use in scientific research and industry production.

      • Machine learning-based prediction and performance study of transparent soil properties

        Bo Wang,Hengjun Hou,Zhengwei Zhu,Wang Xiao 국제구조공학회 2021 Smart Structures and Systems, An International Jou Vol.28 No.2

        An indispensable process of geotechnical modeling with transparent soils involves analyzing images and soil property simulations. This study proposes an objective framework for quantitative analysis of the influential mechanism of three key factors, namely, different aggregate proportions (DAP), solvent ratio (SR), and solute solution ratio (SSR) on transparent soils’ transparency and shear strength. 125 groups of transparent soil samples considering these three factors were prepared to investigate their impact on transparency and shear strength through Elastic Net regression. Spearman correlation analysis was performed for transparency and shear strength. Furthermore, by comparing the performance of XGBoost, GBDT, Random Forest, and SVR after hyperparameter tuning in predicting transparency and shear strength, XGBoost proved to be the optimal machine learning model with the lowest MSE of 0.0048 and 0.0306 and was innovatively adopted to analyze how various factors affect the transparency and shear strength, thus enhancing the interpretability of machine learning. A ranking system, according to the importance scores of XGBoost, shows that SSR was the most important factor affecting both shear strength and transparency of transparent soils, with importance scores being 0.45 and 0.57, respectively. Our study may shed light on the preparation and performance study of transparent soils.

      • Neurochemical Alterations in Methamphetamine-Dependent Patients Treated with Cytidine-5′-Diphosphate Choline: A Longitudinal Proton Magnetic Resonance Spectroscopy Study

        Yoon, Sujung J,Lyoo, In Kyoon,Kim, Hengjun J,Kim, Tae-Suk,Sung, Young Hoon,Kim, Namkug,Lukas, Scott E,Renshaw, Perry F American College of Neuropsychopharmacology 2010 Neuropsychopharmacology Vol.35 No.5

        Cytidine-5′-diphosphate choline (CDP-choline), as an important intermediate for major membrane phospholipids, may exert neuroprotective effects in various neurodegenerative disorders. This longitudinal proton magnetic resonance spectroscopy (<SUP>1</SUP>H-MRS) study aimed to examine whether a 4-week CDP-choline treatment could alter neurometabolite levels in patients with methamphetamine (MA) dependence and to investigate whether changes in neurometabolite levels would be associated with MA use. We hypothesized that the prefrontal levels of N-acetyl-aspartate (NAA), a neuronal marker, and choline-containing compound (Cho), which are related to membrane turnover, would increase with CDP-choline treatment in MA-dependent patients. We further hypothesized that this increase would correlate with the total number of negative urine results. Thirty-one treatment seekers with MA dependence were randomly assigned to receive CDP-choline (n=16) or placebo (n=15) for 4 weeks. Prefrontal NAA and Cho levels were examined using <SUP>1</SUP>H-MRS before medication, and at 2 and 4 weeks after treatment. Generalized estimating equation regression analyses showed that the rate of change in prefrontal NAA (p=0.005) and Cho (p=0.03) levels were greater with CDP-choline treatment than with placebo. In the CDP-choline-treated patients, changes in prefrontal NAA levels were positively associated with the total number of negative urine results (p=0.03). Changes in the prefrontal Cho levels, however, were not associated with the total number of negative urine results. These preliminary findings suggest that CDP-choline treatment may exert potential neuroprotective effects directly or indirectly because of reductions in drug use by the MA-dependent patients. Further studies with a larger sample size of MA-dependent patients are warranted to confirm a long-term efficacy of CDP-choline in neuroprotection and abstinence.

      • KCI등재

        Preparation and Characterization of Emulsified Solid Dispersions Containing Docetaxel

        Ying Chen,Qiongzhi Shi,Zhiyu Chen,Jianling Zheng,Hengjun Xu,Jiazhi Li,Hong Liu 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.11

        An emulsified solid dispersion of docetaxel was prepared and characterized in vitro. In contrast to conventional solid dispersions, emulsifying pharmaceutical excipients and hydroxypropyl methylcellulose (HPMC) as a supersaturation promoter were introduced into the PEG6000-based solid dispersion to further improve its solubilizing capability. The solubility, dissolution in vitro and stability of the prepared emulsified solid dispersions were studied taking into consideration of the effects of different emulsifying excipients, preparation methods and the media. Results of the emulsified solid dispersion of docetaxel showed that the solubility and dissolution at 2 h were 34.2- and 12.7-fold higher than the crude powder. The type of emulsifying excipient used had a significant influence on the dissolution of the emulsified solid dispersion. The dissolution of the emulsified solid dispersion prepared by the solvent-melting method or the solvent method was higher than the melting method. There were no apparent differences among the dissolution media utilized. The status of the drug in the emulsified solid dispersion was observed in an amorphous or a molecular dispersion state by differential thermal analysis and powder Xray diffraction. In conclusion, the incorporation of emulsifying pharmaceutical excipients and HPMC with polymers into a solid dispersion could be a new and useful tool to greatly increase the solubility and dissolution of poorly water-soluble drugs.

      • SCISCIESCOPUS

        Evaluation of MRI resolution affecting trabecular bone parameters: Determination of acceptable resolution

        Kim, Namkug,Lee, June‐,Goo,Song, Youngkyu,Kim, Hengjun J.,S. Yeom, Jin,Cho, Gyunggoo Academic Press 2012 Magnetic resonance in medicine Vol.67 No.1

        <P><B>Abstract</B></P><P>The objective of this study is to evaluate the effect of MR image resolution on trabecular bone parameters and to determine the acceptable resolution that can be accurately analyzed to assess structural parameters. Ten distal femoral condyle specimens of 1 × 1 × 1 cm<SUP>3</SUP> were scanned with a 4.7‐T Bruker BioSpec MRI scanner using a three‐dimensional fast large‐angle spin‐echo sequence with various iso‐cubic voxels sizes (65, 130, 160, 196, 230, and 260 μm). Otsu thresholding was applied to identify voxels containing bone. Conventional bone parameters, structural bone parameters, and skeleton‐based local trabecular thickness (slTB.Th) were evaluated. The Bland–Altman method and correlation indicated that the conventional and structural bone parameters were preserved with an iso‐cubic voxel size up to 230 μm (<I>r</I> > 0.932 and <I>r</I> > 0.843, respectively). In addition, slTB.Th derived from the highest resolution images (65 μm iso‐cubic voxel size), correlated well (<I>r</I> > 0.833) with the values computed from lower resolution images, up to 230 μm, which is twice typical human trabecular thickness range (100–150 μm). The outcome of this study suggests that the various bone parameters were well preserved up to 230 μm images. Magn Reson Med, 2011. © 2011 Wiley‐Liss, Inc.</P>

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