京畿道岸地域 貝類中의 重金屬含量에 關한 硏究

허숙희,고영수 漢陽大學校 韓國生活科學硏究所 1992 韓國 生活 科學 硏究 Vol.- No.10

本 硏究에서는 경기도 연안지역에 棲息하는 貝類의 중금속오염 실태를 파악하기 위하여 강화, 반월, 소래, 인천의 4個 地域에서 바지락, 꼬막, 동죽, 피조개, 모시조개등 5種의 試料를 採取하여 ICP法으로 카드뮴, 납, 아연, 망간 및 구리의 含量을 測定하여 比較 考察하였다. 그 結果 카드뮴은 0.03∼0.25ppm의 범위였으며, 강화의 꼬막이 0.25ppm으로 가장 높았고 인천과 소래의 모시조개가 0.03ppm으로 가장 낮았다. 납은 0.39∼1.01ppm의 범위였으며, 인천의 동죽이 1.01ppm으로 가장 높았고 소래의 꼬막이 0.39ppm으로 가장 낮았다. 아연은 4.91∼10.54ppm의 범위에 있었고, 인천의 모시조개가 10.54ppm으로 가장 높았고 강화의 꼬막이 4.91ppm으로 가장 낮았다. 망간은 0.89∼13.79ppm의 범위에 있었고 인천의 동죽이 13.79ppm으로 가장 높았고 강화의 바지락이 0.89ppm으로 가장 낮았다. 그리고 구리는 검출되지 않았다. 이상의 結果로 볼 때 이들 조개류의 오염의 정도는 크게 문제시되지 않을 것으로 생각된다. This study was performed to investigate the content of heavy metal in shellfishes. The area of samples collection were In Cheon, Kang Wha, Ban Wol, So Rae in Kyungki coast. The kinds of sample were short necked calm(Tapes philippinarum), ark shell (Anadara granosa bisenesis), surf clam(Mactra veneriformis), chest shell (Anadara broughtonii) and corb shell(Paphia philippinarum). The contents of cadmium, copper, lead, zinc, and manganese are determined by ICP (Plasma Scan 710 Labtest Co). The mean of the heavy metal concentration in shellfishes are as follows : The highest value of cadmium was 0.25 ppm in Anadara granosa bisenesis at Kang Wha, and the lowest value of cadmium was 0.03 ppm in Paphia philippinarum at In Cheon and So Rae. The highest value of lead was 1.01 ppm in Mactra veneriformis at In Cheon, and the lowest value of lead was 0.39 ppm in Anadara granosa bisensis at So Rae. The highest value of zinc was 10.54 ppm in Paphia philippinarum at In Cheon, and the lowest value of zinc was 4.91 ppm Anadara granosa bisenesis at Kang Wha. The highest value of manganese was 13.79 ppm in Martra veneriformis at In Cheon, and the lowest value of mangnese was 0.89 ppm in Tapes philippinarum at Kang Wha, Copper was not detected. According to the results the content of heavy metal of shellfishes in Kyungki coast were agreed with the other data of study in this field.

자궁경부암 병기판정 기초검사시 새로운 보조방법으로서 고주파 질식 초음파의 가치

유희석,이은주,장기홍,권혁찬,양정인,김행수,오기석 아주대학교 의과학연구소 1996 아주의학 Vol.1 No.1

To investigate the efficacy of endoluminal ultrasound system (EUS) as a surrogate for high frequency transvaginal ultrasonography and as an optional baseline study in determining parameirial and stromal invasion of early stage cervical cancer, 52 women suspected of cervical cancer underwent EUS. A 12 MHz endoscopic probe was employed to radially scan the cervix for possible lesions suspected to be invasive cancer during a period of 6 months from Feb. 1 to July 1, 1995. Patients also underwent magnetic resonance imaging (MRI) and/or computerized tomography (CT) as a routine mode of baseline study, and were clinically staged by 3 independent physicians specializing in Obstetrics and Gynecology at the Department of Obstetrics and Gynecology, School of Medicine, Ajou University, Suwon, Korea. Thirty one patients subsequently received surgery appropriate for the stage of the disease and the final pathology findings were compared with the results of clinical staging, EUS, MRI/CT by regression analysis. The results showed that there was statistically significant correlation between MRI/CT and pathology (r=0.660, p<0.02), between EUS and pathology (r=0.803, p<0.01), and between clinical staging and pathology (r=0.825, p<0.01). It is concluded that there was significant statistical correlation t>etween EUS, MRI/CT, clinical staging and pathology, but the question remained as to the statistical superiority of EUS over MRI/CT with regard to parametrial invasion and stromal invasion depth assessment. Finally, EUS is useful as an alternative optional diagnostic tool in the baseline study of cervical cancer.

두부 손상이 골절 칭 촉진 시동물 모델 및 유전자 발현 분석

김경희,김학선,문성환,김향,권언해,이환모,박희완,한수봉,문은수 대한정형외과연구학회 2003 대한정형외과연구학회지 Vol.6 No.2

Platinum sensitive 재발성 난소암에서 Carboplatin/Paclitaxel의 효과

장혜진,유희석,임윤경,문세희,장기홍,이정필 대한부인종양 콜포스코피학회 2003 Journal of Gynecologic Oncology Vol.14 No.4

목적 : 재발성 난소암에서 platinum 감수성을 기준으로 2차 항암요법으로 사용한 Carboplatin과 Paclitaxel의 효과를 알아보기 위하여 본 연구를 진행하였다. 연구방법 : 1998년 1월 1일부터 2003년 8월 31일까지 만 5년 8개월 간 아주대학교병원 산부인과에 재발성 난소암으로 입원한 환자 중에서 최초 수술로 난소암을 확진한 후 Cisplatin 또는 Carboplatin 등 platinum 제재가 포함된 항암치료를 받은 후 6개월 이후에 재발한 환자 29명을 대상으로 Carboplatin은 5 AUC를 그리고 Paclitaxel은 175 mg/m^(2)를 투여하였으며, 최소 3회에서 최고 16회까지 투여하였다. 치료효과의 판정은 CT, MRI, Ultrasonography등 영상진단상 암종괴의 크기가 완전히 소실되었을 경우를 완전반응(complete response)으로, 50%이상 감소되었을 경우를 부분반응(partial response)으로, 50% 미만으로 감소되었거나 20% 미만 증가하였을 경우를 불변(stable disease)으로, 그리고 20% 이상 증가되었을 경우를 진행(progressive disease)로 정의하였다. 결과 : 대상 환자에서 완전반응은 6명(21%), 부분반응은 11명(38%), 그리고 불변은 5명(17%)로 전체 반응율 (overall response rate)은 59% 그리고 임상적 유용성(clinical benefit=CR+PR+SD)은 76%이었다. 결론 : 재발성 난소암환자에서 기왕에 사용한 Platinum 제재에 민감한 환자에서는 Carboplatin과 Paclitaxel의 병행 투여가 효과적이었다. Objective : To ascertain the effect of Carboplatin and Paclitaxel combination as a second line regimen for recurrent ovarian carcinoma based on platinum sensitivity. Methods : From January 1st, 1998 through to August 31st, 2003, 29 patients were retrospectively reviewed who had previously underwent primary cytoreductive surgery and adjuvant chemotherapy with Cisplatin or Carboplatin for ovarian carcinoma, and who had later recurred during follow up. All 29 patients had recurred at least 6 months after therapy, and thereafter received second line chemotherapy consisting of Carboplatin (5 AUC) and Paclitaxel (175 mg/㎡) for a minimum of least 3 cycles and a maximum of 16 cycles. Treatment efficacy was assessed by imaging studies including Computerized tomography, Magnetic Resonance Imaging, or Ultrasonography. Complete response was determined as complete disappearance of tumor, partial response at least than 50% reduction in tumor volume, stable disease as less than 50% reduction or less than 20% increase in tumor volume, and progressive disease as more than 20% increase. Results : There was complete response in 6 (21%) patients, partial response in 11 (38%), stable disease in 5 (17%), showing an overall response rate of 59%. The clinical benefit (CR+PR+SD) was 76%. Conclusion : The combination of Carboplatin and Paclitaxel administration seems to be an effective mode of second line therapy in patients with recurrent ovarian carcinoma who had been sensitive to prior platinum based chemotherapy.

초정밀가공기를 이용한 Zerodur의 연삭 특성에 관한 연구

김주환,김건희,한정열,김석환,원종호 한국공작기계학회 2003 한국공작기계학회 춘계학술대회논문집 Vol.2003 No.-

We explored a new rough grinding technique on optics materials such as Zerodur. The facility used is a NANOFORM-600 diamond turning machine with a custom grinding module and a range of diamond resin bond wheel. The grinding parameters such as workpiece rotation speed, depth of cut and feed rate were altered while grinding the workpiece surfaces of 20mm in diameter. Surface roughness is measured by Form Talysurf series2. Our target is to define grinding conditions producing the surface roughness better than 0.02μm Ra and the form accuracy of around 0.2μm PV.

인체동작분석시 Wavelet변환을 이용한 영상자료의 보간 및 분석

김기형,김민기,유경석,김희영 한국운동역학회 1997 한국운동역학회지 Vol.7 No.1

Inputting data of human motion analysis means signal processing of changes in linear time dependent spatial coordinates of anatomical landmarks. Commercial CCD camera appears to be sampling 30 fps imposing limitation for human motion analysis which needs at least 60 fps. For the interpolation 60 fps fast algorithm of inverse wavelet transformation (IWT) was utilized producing 60 fps out of normal 30 fps. The original data from free fall and cycling motion of lower extremity were used to test the applicabiility of wavelet interpolation to human motion analysis. The test results showed linear relationship between two data sets. In the test of free fall, data curves of two sets, theoretical 30 frame data and 60 frame data after inverse wavelet transformation, appeared to be almost identical. Regression analysis of free fall test showed R^2 = 0.99 meaning Y = IWT. In the test with cycling motion of lower extremity % cycle of maximum flexion and extension at the joints was compared between two data sets showing same result, as in free fall test.

국내에서 분리된 Extended-Spectrum β-Lactamase 생성 Escherichia coli와 Klebsiella pneumoniae의 빈도 및 유형

홍성근,김선주,정성훈,장철훈,조성란,안지영,신종희,이혜수,송원근,어영,염종화,용동은,이경원,정윤섭 대한임상미샐물학회 2003 Annals of clinical microbiology Vol.6 No.2

냉기치료후 슬관절강내의 온도변화

백승석,최기섭,박시복,이상건,김영호,양길태,장윤희 大韓再活醫學會 1998 Annals of Rehabilitation Medicine Vol.22 No.2

Effects of Hepatocyte Growth Factor on the Expression of Matrix Metalloproteinases and Their Tissue Inhibitors During the Endometrial Cancer Invasion in a Three-Dimensional Co-Culture

( Hee Sug Ryu ) 대한산부인과학회 2004 대한산부인과학회 학술대회 Vol.90 No.-

Status and Causes Related to Internet Addiction in Korean Elementary Students

Hee Sug Cho,Hyang Yeon Lee 한국간호과학회 2007 한국간호과학회 학술대회 Vol.2007 No.11