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        청소년기에 있어서의 정신의학적 위험도 평가

        이대희,최희정 大韓神經精神醫學會 1982 신경정신의학 Vol.21 No.3

        청소년기 학생들의 정신과적 위험도를 평가하는데 Anthony's Risk Profile의 적용가능성과 방법론상의 문제점들을 알아보기 위해서 청소년 640명과 청소년기 정신과 환자 23명에게 설문지법으로 조사한바 다음과 같은 결과를 얻었다. 1. 총위험도점수는 발달시기별, 남녀별 차이는 없었으나, 도시보다 농촌에서 높은 경향을 보였다. 2. 각 소제목별 비교에 있어서는 「체질부담」, 「발달부담」, 「신체질환부담」 및 「환경부담」이 도시보다 농촌에서 높은 것으로 나타났다. 그리고 「발달부담」, 「환경부담」과 「충격부담」은 여자보다는 남자에서 높은 것으로 나타났으며 「충격부담」은 나이가 들어감에 따라 증가하는 것으로 나타났다. 3. 환자군은 정상군에 비해 높은 총위험도 점수를 나타냈으며, 「출산부담」을 제외한 모든항목 특히 「유전부담」과 「충격부담」이 현저히 높은 것으로 나타났다. 4. 결론적으로 청소년의 정신과적 위험도를 측정하는데 ARP설문지를 이용할 수 있을 것으로 보이며 다만 더 자세한 조사를 위해서는 몇몇 항목의 수정이나 첨가가 필요할 것으로 생각된다. The purpose of this study was to investigate the discriminating power and the applicability of the 'Anthony's Risk Profile(ARP) which is a tool for assessment of psychiatric risk of an individual. After translation into Korean, the ARP questionnaires were sent to the parents of 160 preadolescents, 240 early adolescents and 240 middle alolescents. (Male: Female=1:1, Urban:Rural 1:1) Six hundred and eight questionnaires were returned and the data of 578 questionnaires were analyzed statistically. Then the stratified sample of 23 rural boys were chosen and compared with a 23 psychiatric patient group. Some of the results and conclusions are as follows: 1. All subjects but one belonged to the range of low risk of 0 to 13 scores. 2. The subjects whose total risk score ranged between 7-13 were significantly more in rural samples than in the urban probably due to increased environmental and subsequent physical ill-health loading. 3. The developmental, environmental and traumatic loading were greater in male samples than in the female. 4. Patient group showed higher total risk score and higher risk of all sub-categories except reproductive loading than normal group 5. In conclusion, the ARP questionnaire was found to have some discriminating power between different groups and found applicable to Korean abolescents. The authors hinted at a possibility of revising some items and addition of new items such as sibling rivalry or parental overprotection.

      • 흥미로운 구조를 가진 Dipyrrolylbenzene들의 합성에 관한 연구

        정대일,김인식,정두희,박철우,김윤영 東亞大學校 大學院 1996 大學院論文集 Vol.21 No.-

        1-(2-Aminophenyl)pyrrole 20a and 1,2-dipyrrolylbenzene 17a were synthesized by using 1,2-phenylenediamine 16a with 2,5-dimethoxytetrahydrofuran 12 in glacial acid. 1-(3-Aminophenyl)pyrrole 20b and 1,3-dipyrrolylbenzene 17b were obtained by using 1,3-phenylenediamine 16b with 2,5-dimethoxytetrahydrofuran 12 in glacial acetic acid. 1,4-Dipyrrolybenzene 17c was synthesized by using 1,4-phenylenediamine 16c with 2,5-dimethoxytetrahydrofuran 12 in glacial acetic acid. Aminophenylpyrroles 20 and dipyrrolylbenzenes 17 were respectively synthesized by the treatment of 1,2-phenylenediamine 16a, 13-phenylenediamine 16b, 1,4-phenylenediamine 16c and 2,5-dimethoxytetrahydrofuran 12 in no solvent, acrylic acid, silica-gel, acrylic acid + silica-gel + acetic acid instead of glacial acetic acid. In case of silica-gel + acetic acid among various methods reactivity about synthesis of dipyrrolylbenzene 17 was best. 9-Phenylcarbazole 15 was synthesized by treatment of 1-phenylpyrrole 13 with 2,5-dimethoxytetrahydrofuran 12 in glacial acetic acid.

      • 박테리아의 生育에서 Aspergillas flavus 抽出物과 SH group의 相關作用

        李大熙,崔鎬亨 공주대학교 사범대학 과학교육연구소 1987 과학교육연구 Vol.19 No.1

        Aspergillus flavus 抽出物과 Aflatoxin 및 ρCMB가 박테리아의 생장과 증식과정에 미치는 형태와 억제의 정도 및 작용의 유사성을 조사하기 위하여 이들 각각의 저해 물질들을 배양액에 처리하여 박테리아를 배양 실험하였다. 또한 SH group이 이들 저해물질들의 저해작용을 완화할 수 있는지의 여부를 조사하기 위하여 각 저해물질과 glutathione을 同量으로 처리하여 박테리아의 증식변화를 추적하였다. 얻어진 결과는 다음과 같았다. 1. Aspergillus flavus 抽出物 1mg(dry weight) 은 박테리아 증식을 50% 억제하였다. 2. Aflatoxin B₁을 농도별로 배양액에 처리한 결과 박테리아 증식은 10??M 에서 45% 10??M에서 21%정도 억제되었다. 3. ρCMB 10??M에서 박테리아 생장과 증식은 45% 억제되었다. 4. Aflatoxin B₁과 ρCMB는 박테리아의 생육억제의 크기나 형태변화 유발등에서 유사하였다. 그러나 생육장해를 주는 방법에 있어서는 서로 차이가 있었다. 5. ρCMB의 장해는 glutathione에 의하여 보완적이었으나 Aflatoxin B₁에 의한 장해는 거의 보완되지 않았다. 6. Aspergillus flavus 抽出物에 의하여 박테리아의 증식이 억제되었을 경우 glutathione처리를 하였을 때 14%정도 보완되었다. 7. Aspergillus flavus 抽出物중에서 박테리아 生育을 억제하는 성분은 Aflatoxin만이라고 한정할 수 없었으며 또한 그 저해작용은 SH아미노산에 의하여 상당히 보완될 수 있었다. In order to examine mode and rate of inhibition and the similarity of biochemical process that Aspergillus flavus extract aflatoxin and ρCMB effect on the process of its growth and reproduction of bacteria, it was experimented as treating each inhibitor into bacterial culture medium. In order to examine whether SH group could be on the decrease in the rate of inhibition, the reproductive mode in bacteria was investigated by means of treating as the same amount of each inhibitor and glutathione. Reproduction and groth of bacteria was decreased about 50% by Aspergillus flavus extract lmg(dry weight) Reproduction of bacteria was inhibited about 45% in 10??M and 21% in 10??M. The reproduction of the bacteria was decreased 45% in 10??M ρCMB-treated medium. Aflatox B₁and ρCMB showed the similar tendency of the inhibition rate in reproduction and causing the alternation of morphologic modification of bacteria. However, there were dissimiliar to the phenomenon of inhibition. The inhibition of ρCMB was offset by glutathione in the large percentage but the inhibition by aflatoxin was not almost offset by aflatoxin. Inhibition by Aspergillus flavus extract was offseted about 14% by treatment of 10??M glutathione. Inhibitory components of Aspergillus flavus extract could not define only aflatoxin and inhibition could be same offset by glutathione.

      • 1,2-Benzisothiazol-3-one-1,1-Dioxide 유도체의 합성

        정대일,정희철,변석인,이용균,박유미,최순규,한정태 東亞大學校附設基礎科學硏究所 2002 基礎科學硏究論文集 Vol.19 No.1

        사카린 유도체는 제초제, 항독성, 살균제 등에 광범위하게 연구되어져 오고 있다. 새로운 농략 활성을 가진 물질을 합성하기 위해 먼저 선도물질로 사카린 1을 산화, 염소화 시킨 3-chloro-1,2-benzisothiazol-1,1-dioxide(BID-CI) 2와2cholromethy-1,2-benzisohizol-3-one1,1-dioxide 4를 합성하였다. 선도물질, amines, imidazoles, trones등과 반응시켜 다음과 같은 물질들을 얻었다. ; 3-cyclohexylamino-1,2-benzisothiazol-1,1-dioxide 6, 3-furylamino-1,2-benzisothiazol-1,1-dioxide 8, 3-(3-imidazol)-1,2-benzisothiazol-1,1-dioxide 10, 3-(2-methy-3-imidazol)-1,2-benzisothaizol-1,1-dioxide 12, 2-(3-imidazol)methy-1-1,2-benzisothiazol-3-one-1,1-dioxide 13, and 2-(-3-imidazol)methyl- 1,2-benzisothiazol-1,1-dioxide 14.

      • Nortropinone 유도체로부터 Nortropane Spirohydantoin 유도체의 합성

        정대일,박유미,박종훈,김윤영,정두희,김인식 東亞大學校 1998 東亞論叢 Vol.35 No.-

        The nortropinones 11 (tropinone lla, N-isopropylnortropinone 11b, N-Carbethoxynortropinone 11c, N-furfurylnortropinone 11d, N-(p-methoxyphenyl)nortropinone 11e) were respectively synthesized by the treatment of acetonedicarboxylic acid 8 with, 2, 5-dimethoxytetrahydrofurane 9 in various amines 10 (methylamine 10a, N-isopropylamine 10b, ethylcarbamate 10c, furfurylamine 10d, p-anisidine 10e). The nortropane spirohydantoins 14 (tropane spirohydanttoin 14a, N-isopropylnortropane spirohydantoin 14b, N-Carbethoxynortropane spirohydantoin 14c, N-furfurylnortropane spirohydantion 14d, n_(p-methoxyphenyl) nortropane spirohydantoin 14e) were respectively synthesized by the treatment of synthesized nortropinones 11 (tropinone 11a 54%, N-isopropylnortropinone 11b 50%, N-Carbethoxynortropinone 11c 58%, N-furfurylnortropinone 11d 31%, N-(p-methoxyphenyl) nortropinone 11e, 70%) with potassium cyanide 12, ammonium carbonate 13.

      • 조리방법에 따른 식품 중 영양소 잔존률(retention factor)에 관한 연구(Ⅰ) : 채소류 및 감자류 Vegetablesn ane potatoes

        김대병,장영미,김인복,이혜영,장재희,박정현,엄세정 식품의약품안전청 2000 식품의약품안전청 연보 Vol.4 No.-

        조리조건에 따른 식품의 영양소 잔존를을 측정하여 보다 정확한 조리식풍에 의한 영양소 섭취량을 평가할 수 있도록 하기 위하여 합리적인 영양소섭취량 조사, 영양 평가를 위한 개선책을 제시하고자 끓였다. 대상 시료와 조리법은 시금치(데치기, 끓이기), 배추(끓이기), 콩나물(데치기, 끓이기), 호박(끓이기, 볶기). 당근(끓이기, 볶기), 우엉(조림), 감자(끓이기, 볶기)이었으며, 조리 전 후의 비타민 A(β -carotene), Bl, B2, C, E, 나이아신, 칼슘, 철, 아연, 칼륨, 인, 나트륨의 함량을 분석하여 조리법에 따른 잔즌률을 국하였다. 조리조건별 잔존률을 구한 결과 무기질은 데치기의 경우 조리수를 제거하므로 손실이 있었으나 끓이기, 볶기 등의 조리법에서는 손실이 거의 없었다. 비타민 A와 I는 대부분 80%이상으로 많이 손실되지 않았으며 비타민 Bi은 데치기가 가장 낮았고, 조림, 괄이기, 볶기의 순으로 잔존률이 높았다. 비타민 B2와 나이아신은 비타민 Bi보다는 잔존를이 높은 경향이었다. 비타민 C는 대부 분의 조리법에서 크페 손실되었다. 본 연구의 결과는 합리적이고 정확한 영양소 섭취량 평가를 위한 기초자료로서 기존의 평가방법을 개선 보완하여 영양소섭취량 평가으 과학화에 기여할 것으로 기대된다. In various mutrition activities, the necessary values of nutrient intake were usually calculated from food composition tables which have nutrient contents of raw ingredients and dishes, but Korean food composition tables of dishes were lacking, So we studied todetermine the nutnent retention factors(RF) of vegetables and potatoes by cooking methods. Atfirst, we surveyed cooking methods of vegetables and potatoes, and selected major vegetablesand cooking methods. Selected items and cooking methods were sp.mach(blanching and boiling),cRnese cabbage(boiling), soybean sprout(bBanchlng and boiling), pumpkin(boiling andstir-frying), carlot(boiling and stir-frying), burdock(braising), and potato(boiling and stir-frying)We analyzed 6 vitamins luhich were vitamin A(β-carotene), Bl, B2, C, E, and niacin, and 6minerals which were calciurrl, iron, zinc, potassium, phosphorus, and sodium. The results wereas follows : Minerals almost retained in boiling, stir-frying, except in blanching method, RF ofvitamin A and I were 80% or more. RF of vitandn Bl were decreased in order of sfir-frying,boiling, braising, blanching and the RF of vitamin B2 and niacin were higher than vitandn Bl,RF of the vitamin C were varird in So~90% in all cooking methods

      • 韓牛 末梢血液 淋巴球의 在來山羊 赤血球 Rosette形成

        宋憙鍾,金鍾冕,姜明大,蔡孝錫 全北大學校 附設 畜産開發硏究所 1988 畜産開發硏究報告 Vol.2 No.-

        In order to enumerate the T lymphocytes in bovine peripheral blood lymphocytes(PBL) by E rosette assay, KGRBC were treated with various concentration of 2-aminoethylisothiouronium bromide hydrobromide(AET) and dextran(Dex), singte or combination. The PBL from 10 clinically normal Korean native cattle were formed as low percentage of spontaneous E rosette(6.7±2.4%) in control group, whereas KGRBC treated with 0.1M AET for 20 minutes and 8%Dex were formed as 37.3±2.7% and 45.1±2.1%, respectively. And the synergistic effects were noted no less than 66.5±5.6% when the KGRBC treated with 0.1M AET and 8% Dex subsequently. These results suggest that the KGRBC would be a useful agent for the enumeration of T tymphocytes by E rosette assay in bovine PBI.

      • Thioamide와 Benzothiazole 유도체의 합성

        정대일,신규하,김인식,김윤영,정두희,이용균 東亞大學校 1998 東亞論叢 Vol.35 No.-

        The thioamides; {N-(6-methyl-2-pyridinecarbothionyl)-3-methoxyaminobenzene (27), N-(6-methyl-2-pyridinecarbothionyl)-4-methoxyaminobenzene (29), N-(6-methyl-2-pyridine-carbothionyl)-3-ethoxyaminobenzene (31), N-(6-methyl-2-pyridinecarbothionyl)-4-ethoxyamion-benzene (33), N-(6-methyl-2-pyridinecarbothionyl)-3-bromoaminobenzene (35), N-(6-methyl-2-pyridinecarbothionyl)4-bromoaminobenzene (37), N-(6-methyl-2-pyridinecarbothionyl)-3-chloroaminobenzene (39), N-(6-methyl-2-pyridinecarbothionyl)-4-chloroaminobenzene (41)} were synthesized by the treatment of 2,6-lutidine(22) with sulfur in aniline derivatives (23). The benzothiazole derivatives; {5-methoxy-2-(6-methylpyridy)benzothiazole (46) and 6-ethoxy-2-(6-methylpyridyl)benzothiazole (47)} were respecively synthesized by the treatment of synthesized thioamides; N-(6-methyl-2-pyridinecarbothionyl)-3-methoxy-aminobenzene (27) and N-(6-methyl-2-pyridinecarbothionyl)-4-ethoxyaminobenzene (33) with zirconium (Ⅳ) oxide catalyst in sodium carbonate solution.

      • 사상규칙과 소함수를 이용한 간호정보시스템의 스키마 사상 모듈의 설계 및 구현

        김대희,전종훈 명지대학교 산업기술연구소 2001 産業技術硏究所論文集 Vol.20 No.-

        Data interchange module for data sharing in a distributed database system envirionment is indispensible. Especially, inconsistency problem incurred by heterogeneous schema and database management system are known to be the most difficult one. This paper proposes a schema mapping method for data interchange between nursing information system and hospital information system. The method is based on the use of rule map and mini functions and the former is for providing schema mapping information and the latter is tailored for each individual database management system. The rule map and mini function resolves mismatch problem, which in turn makes it possible to implement effective data interchange module.

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