응급의료센터를 내원한 헬기이송 환자의 분석

권혜란,이영현,조남수 광주보건대학 2000 論文集 Vol.25 No.-

This study was a synoptic assessment of availability of the emergency medical transport by EMS helicopter. There have been 3 helicopters that belong to the Chonnam Regional Police Department. All of them could have been used in transporting emergency medical patients, especially when the patients would be islanders or be occurred in mountainy areas. During the past 5 years from the early 1995 to the late 1999, however, a total of 27cases were transported to the Chosun Univertiy Emergency Medical Center by EMS helicopter. In order to augment the availability or feasibility of the patient transport by EMS helicopter, the emergency medical technician or staff should be accompanied. At the same time, the merits of using the EMS helicopter should be disseminated to the general population.

Poster Session 1 : oral Presentation ; Signal Transduction : The Ras-MEK pathway is required for pro-apoptotic BNIP3 induction by nitric oxide treatment of macrophages

( Hyun Jung An ),( Oky Maeng ),( Chung Hyun Lee ),( Hay Young Lee ),( Sang Gi Paik ) 한국생화학분자생물학회 (구 한국생화학회) 2005 62회 KSBMB Annual Meeting in 2005 Vol.- No.-

Poster Session 1 : The Ras-MEK pathway is required for pro-apoptotic BNIP3 induction by nitric oxide treatment of macrophages

( Hyun Jung An ),( Oky Maeng ),( Chung Hyun Lee ),( Hay Young Lee ),( Sang Gi Paik ) 한국생화학분자생물학회 (구 한국생화학회) 2005 생화학분자생물학회 춘계학술발표논문집 Vol.2005 No.-

Poster Session : Ras-MEK-HIF pathway regulates nitric oxide-induced death of macrophages by inducing BNIP3 expression

( Hyun Jung An ),( Oky Maeng ),( Kyoung Hee Kang ),( Young Hun Yook ),( Chung Hyun Lee ),( Jie Oh Lee ),( Young Sang Kim ),( Sang Gi Paik ),( Hay Young Lee ) 한국생화학분자생물학회 (구 한국생화학회) 2006 생화학분자생물학회 춘계학술발표논문집 Vol.2006 No.-

출산 전후 어머니 스트레스 변화의 종단적 연구

이현정(Lee Hyun Jung),현온강(Hyun On Kang),나종혜(Rha Jong Hay) 한국지역사회생활과학회 2006 한국지역사회생활과학회지 Vol.17 No.3

Copper(Ⅱ) Sorption Mechanism on Kaolinite : An EPR and EXAFS Study 전자상자성공명 및 EXAFS 연구

Hyun, Sung Pil,Kim, F. Hayes 한국광물학회 2004 한국광물학회지 Vol.17 No.1

캐올리나이트(KGa-lb) 표면에 수착된 구리를 전자상자성공명(electron paramagnetic resonance)과 ExAFS (extended X-ray absorption fine structure) 분광법을 이용하여 연구하였다. 수착된 구리는 상온에서 g_(iso)=2.19의 등방성 전자상자성공명 흡수 신호를 보여 준다. 77 K에서 이러한 등방성 신호는 g_(∥)=2.40, g_(i)=2.08, 그리고 A_(∥)=131 G의 전사상자성공명 파라미터를 가지는 축대칭 이방성 신호로 바뀐다. 전자상자성공명 분석 결과로부터 수착된 구리 이온이 찌그러진 CuO_(6) 팔면체구조의 외부권착물을 형성함을 알 수 있다. 수착 실험에서 용액의 pH가 증가함에 따라 수착된 구리의 양은 증가하였다. 그러나 등방성 신호는 수착된 구리의 양에 단순 비례하지는 않았다. 수착된 구리 이온이 높은 pH 조건에서 표면 침전을 형성함을 가정함으로써 이러한 불일치를 해소할 수 있다. EXAFS 결과로부터 이러한 표면 침전의 존재를 확인할 수 있었다. 최적의 fitting 결과는 수착된 구리 이온이 1.96Å 거리에 결합된 4개의 수평 방향 산소와 2.31 Å 거리에 결합된 2개의 축방향 산소로 이뤄진 첫 번째 산소 껍질과 함께 3.08 Å 거리에 평균 6.8개의 구리 이웃 원자들을 가짐을 보여준다. 이 연구는 캐올리나이트에 수착된 구리 이온의 국소 환경이 용액의 pH와 표면 농도에 따라 변화하며 그러한 변화를 연구하는데 전자상자성공명과 EXAFS가 효과적으로 활용될 수 있음을 보여 준다. Copper(Ⅱ) sorbed on kaolinite (KGa-1b) was studied using electron paramagnetic resonance (EPR) and extended X-ray absorption fine structure (EXAFS) spectroscopy. The sorbed copper(Ⅱ) had an isotropic EPR signal with g_(iso)= 2.19 at room temperature. At 77 K, the isotropic signal converted to an axially symmetric anisotropic signal with g_(∥) = 2.40, g_(l) = 2.08, and A_(∥) = 131 G. These EPR results suggest that the sorbed copper(II) forms an outer-sphere surface complex with a tetragonally distorted CuO_(6) octahedral structure on the kaolinite. In the sorption measurement, the amount of sorbed copper increased with increasing pH of the solution. However, the intensity of the isotropic EPR line was not directly proportional to the amount of sorbed copper. This discrepancy was resolved by assuming the formation of a surface precipitate at higher pH that is invisible by EPR. The EXAFS data confirmed the existence of the surface precipitate. The best fit for the EXAFS of the sorbed copper showed that each copper on the kaolinite had 6.8 copper neighbors located 3.08 A from it, in addition to the first shell oxygen neighbors, including 4 equatorial 0 at 1.96 A and 2 axial 0 at 2.31 A. This work shows that the local environment of the copper sorbed on the kaolinite changes as a function of pH and surface loading, and that the EPR and EXAFS are useful in studying such changes.

Abiotic reductive dechlorination of cis-DCE by ferrous monosulfide mackinawite

Hyun, Sung Pil,Hayes, Kim F. Springer-Verlag 2015 Environmental Science and Pollution Research Vol.22 No.21

Distribution of mosquitocidal Bacillus thuringiensis and Bacillus sphaericus from sediment samples in Florida

Hyun-Woo Park,Sabrina R. Hayes,Clare M. Mangum 한국응용곤충학회 2008 Journal of Asia-Pacific Entomology Vol.11 No.4

A spore-forming soil bacterium, Bacillus thuringiensis subsp. israelensis has been used most widely and extensively in many regions of the world to control mosquito and blackfly larvae. It contains four major proteins in three different inclusion types assembled into a spherical parasporal body. Although no resistance to B. thuringiensis subsp. israelensis has been reported in the field yet, laboratory selection of mosquitoes with B. thuringiensis subsp. israelensis Cry proteins results in high levels of resistance. Furthermore, mosquito resistance to any of these proteins results in significant cross-resistance to the others. Another spore-forming bacterium, B. sphaericus also has been used to control mosquito larvae. However, as this bacterium contains only a single binary toxin, high levels of resistance to B. sphaericus have already been reported in the field in several countries. Consequently, there is an urgent need to search for and isolate new indigenous and more effective mosquitocidal bacterial strains. Therefore, in this study, we have screened sediment samples from various mosquito-breeding sites in Florida to isolate novel mosquitocidal bacilli with high toxicity. The results showed that mosquitocidal B. thuringiensis and B. sphaericus can be found almost everywhere. A spore-forming soil bacterium, Bacillus thuringiensis subsp. israelensis has been used most widely and extensively in many regions of the world to control mosquito and blackfly larvae. It contains four major proteins in three different inclusion types assembled into a spherical parasporal body. Although no resistance to B. thuringiensis subsp. israelensis has been reported in the field yet, laboratory selection of mosquitoes with B. thuringiensis subsp. israelensis Cry proteins results in high levels of resistance. Furthermore, mosquito resistance to any of these proteins results in significant cross-resistance to the others. Another spore-forming bacterium, B. sphaericus also has been used to control mosquito larvae. However, as this bacterium contains only a single binary toxin, high levels of resistance to B. sphaericus have already been reported in the field in several countries. Consequently, there is an urgent need to search for and isolate new indigenous and more effective mosquitocidal bacterial strains. Therefore, in this study, we have screened sediment samples from various mosquito-breeding sites in Florida to isolate novel mosquitocidal bacilli with high toxicity. The results showed that mosquitocidal B. thuringiensis and B. sphaericus can be found almost everywhere.

Abiotic U(VI) reduction by aqueous sulfide

Hyun, S.P.,Davis, J.A.,Hayes, K.F. Pergamon Press ; Elsevier Science Ltd 2014 Applied geochemistry Vol.50 No.-

Reactions with aqueous sulfide are important in determining uranium (U) geochemistry under sulfate reducing conditions. This paper reports on abiotic reduction of U(VI) by aqueous sulfide under a range of experimental conditions using batch reactors. Dissolved U concentration was measured as a function of time to study the effects of chemical variables including pH, U(VI), S(-II), total dissolved carbonate (CARB=H<SUB>2</SUB>CO<SUB>3</SUB><SUP>*</SUP>+HCO<SUB>3</SUB><SUP>-</SUP>+CO<SUB>3</SUB><SUP>2-</SUP>), and Ca<SUP>2+</SUP> concentration on the U(VI) reduction rate. Solid phase reaction products were characterized using X-ray diffraction, X-ray absorption spectroscopy, and transmission electron microscopy. The chemical variables had impacts on the solid phase U(VI) reaction products as well as the reduction rates by aqueous sulfide. The solid U reaction product at circumneutral pH was identified as uraninite (UO<SUB>2+x(s)</SUB>). Under basic pH conditions, whether a precipitate occurred depended on Ca<SUP>2+</SUP> and CARB concentrations. U(VI) reduction was faster under higher S(-II) concentrations but was slowed by increased dissolved Ca<SUP>2+</SUP> or CARB concentration. In the absence of dissolved CARB and Ca<SUP>2+</SUP>, a rapid decrease in dissolved U concentration occurred at circumneutral pH, while virtually no decrease was observed at pH 10.7 within the experimental timeframe of two days. The U(VI) reduction rate was proportional to the total concentration of free uranyl plus its hydrolysis complexes even at minor to trace concentrations. Dissolved Ca<SUP>2+</SUP> and CARB slow abiotic U(VI) reduction by forming stable Ca-U(VI)-carbonato soluble complexes that are resistant to reaction with aqueous sulfide. U(VI) reduction was slow in a synthetic solution representative of groundwater at a uranium mill tailings site. This study illustrates that abiotic U reduction by aqueous sulfide can significantly vary under typical ranges of chemical conditions in groundwater and newly demonstrates the importance of dissolved Ca<SUP>2+</SUP> in the abiotic U(VI) reduction by aqueous sulfide. The results contribute to our understanding of the impact of sulfate reducing conditions on U speciation in groundwater systems undergoing bioreduction conversion of U(VI) to less mobile U(IV) solid phases.

X-ray absorption spectroscopy study of Cu(II) coordination in the interlayer of montmorillonite

Hyun, S.P.,Hayes, K.F. Elsevier 2015 Applied clay science Vol.107 No.-

Cu(II) coordination in the interlayer of an expandable clay mineral montmorillonite is studied using X-ray absorption spectroscopy (XAS) along with electron paramagnetic resonance (EPR) and X-ray diffraction (XRD). Ab initio calculations are performed using FEFF code to reproduce the X-ray absorption near edge structure (XANES) and extended X-ray absorption fine structure (EXAFS) portion of the experimentally measured XAS spectra. Cu(II) coordination changes depending on the Cu(II) loading and hydration state of the interlayer. XRD shows that the Cu-saturated montmorillonite has d<SUB>001</SUB>-spacing values corresponding to the interlayer thickness of four and one water layer(s) for the hydrated and dehydrated interlayers, respectively. EPR shows that Cu(II) in the fully hydrated, unsaturated interlayer behaves similarly to free Cu(II) ion in a bulk aqueous solution, while Cu(II) forms a square planar complex in the dehydrated interlayer. Cu(II) in the fully hydrated, Cu-saturated montmorillonite has a characteristic singlet 1st derivative XANES spectrum. FEFF calculations show that this singlet feature originates from a quasi-regular octahedral coordination of water molecules around the interlayer Cu(II) atom. All other samples and model compounds including the dry Cu-saturated montmorillonite, wet and dry unsaturated montmorillonite, aqueous Cu(II), cupric nitrate salt (Cu(NO<SUB>3</SUB>)<SUB>2</SUB>.4.5H<SUB>2</SUB>O), and Cu(II) hydroxide precipitates have doublet 1st derivative XANES spectra. FEFF calculations suggest that the doublet features arise from an axially elongated octahedral coordination under the Jahn-Teller effect or square planar coordination. FEFF calculations of the EXAFS spectra as a function of the axial oxygen bond length demonstrate that a destructive interference between backscattering from equatorial oxygen (O<SUB>eq</SUB>) and that from axial oxygen (O<SUB>ax</SUB>) atoms leads to an apparent coordination number (CN) less than six expected for the tetragonal coordination, with the farther, loosely bound axial oxygen atoms making a minor, yet negative contribution to the CN determined by the EXAFS analysis. This study shows that Cu(II) has interchangeable octahedral, tetragonal, and square planar coordinations in the interlayer of montmorillonite, depending on Cu(II) loading and degree of hydration. The quasi-regular octahedral coordination of the interlayer Cu(II) in montmorillonite is a new finding of this study.