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      • KCI등재

        전란' 소재 애정전기소설의 성립과 발전에 대한 시론 : 「취취전(翠翠傳)」과「이생규장전(李生窺墻傳)」을 중심으로

        정환국 민족문학사학회 2001 민족문학사연구 Vol.19 No.-

        This study is a research for the formation and development of romantic Chuanchi dealing with the war, taking note of the fact that romantic Chuanchi dealing with the war had been continuously written. The first short story was 「A story of Yi Saeng's peeping in the wall」in 『New Stories from Geum-Oh』. We could find out a form in 「A story of Yi Saeng's peeping in the wall」in which a man and a woman met and parted during the war, and the form made a stream in the Korean novel until seventeen century. The narrative form, I think, connotes a significant clue to understand the formation and development of the Korean novel, so it could be meaningful to elucidate the characteristics of the form. I tried to find a new way to explain by using the e method of 'compare and contrast'. 「A story of Yi Saeng's peeping in the wall」in 『New Stories from Geum-Oh』resembles 「A story of Chui Chui」in 『New Stories read by snuffing a lampwick』in Yuan Dynasty in the aspects of structure. And 「A story of Chui Chui」is also connected with 「A story of Madame Yoo」, a Chuanchi of Tang Dynasty. I should compare it again with 「A story of Yi Saeng's peeping in the wall」. As a result, I could make out the formative process of romantic Chuanchi dealing with the war, because 「A story of Madame Yoo」is in a state of not so fully embodying the war into the structure. It is thought that a current of the Korean novel could be objectified from getting hold of the stream of Chinese novel as well as the stream of Korean.

      • KCI우수등재
      • KCI등재

        酒精과 神經傳達物質-文獻 考察

        田珍淑,張煥一 大韓神經精神醫學會 1984 신경정신의학 Vol.23 No.3

        주정은 중추신경계에 여러 생화학적 변화를 일으킬 수 있으며, 급성 및 만성 주정투여시의 효과는 하나의 생물학적인 연속으로 볼 수 있다. 즉, 이러한 변화는 주정의 일차적 효고 및 이에 대한 이차적인 평형반응에 의한다. 1. 주정의 급격한 투여에 의한 효과는 생물학적 막(biological membrane)의 화학적 변화보다는 비특이적인 생물리적 변화에 의해 시작되며, 전반적으로 중추신경기능의 억제를 가져온다. 2. 주정의 만성투여에 의한 효과는, 생물학적 막의 지방성분의 변동으로 인한 막의 유동성의 변화에 대한 생리학적인 적응의 결과로서 내성 및 의존이 생기게 된다. 금단시에는 억압되었던 중추신경계가 보상적인 과잉흥분을 보인다. 3. 1970년대 이래로 주정의 중추신경전달물질에 대한 역할을 이해하고자 하는 시도가 있었으나, 아직까지 의견이 분분하며, 주정은 opiate를 제외하고는 특이한 수용체에 작용하는 것 같지는 않으며, catecholamine과 GABA는 상당히 연관되는 것으로 보이나, 그 외에 serotonin, acetylcholine 및 1980년대 들어서 관심이 높아지고 있는 peptides와의 관계는 아직 불명하다. Alcohol is capable of producing many biochemical changes in central nervous system. Theses changes are composed of direct primary effect and secondary homeostatic response. In this regard, acute and chronic administration seems to be a biological continuum. 1. The primary effect of acute alcohol administration is initiated with nonspecific biophysical mechanism rather than biomembrane, and produces generalized depression of neuronal function. 2. Chronic alcohol administration produces tolerance and physical dependence due to physical adaptation to the changes of membrane fluidity caused by alteration of lipid composition in biological membrane. Upon withdrawal, central nervous system depression is replaced by compensatory neuronal hyperexcitability. 3. Since 1970, investigators have been trying to understand the role of alcohol on neurotransmitters. Although controversial, it seems that catecholaminergic and gamma-aminobutyric acidergic systems are significantly involved. But, the relation with other neurotransmitters such as serotonin, acetylcholine, and peptides which have been attracting much interest since 1980, is not clarified.

      • 디메틸설폭사이드에서의 고분자량 아크릴로니트릴 중합체 및 공중합체의 합성과 그의 섬유에로의 응용

        유승운,박환만,이수,문규열 國立 昌原大學校 基礎科學硏究所 1993 基礎科學硏究所論文集 Vol.4 No.-

        To obtain polyacrylonitrile of high molecular weight (>1,000,000) under optimum solution polymerization condition in dimethylsufoxide, which has very low chain transfer constant, using an azobisisobutyronitrile as initiator, we examined the effect of water content in reaction mixture, and the concentration of monomer and initiator on the conversion rate and polymer properties. As a result, homo PAN with Mw=1,330,000 and about 12% of conversion was prepared under the condition of[AN]=7 mole/1 and[AIBN]=6.0x10-4 mole/1 at 50℃. Copolymers with AN and other vinylic monomers such as methyl acrylate, itaconic acid, and acrylamide, having considerably high molecular weight were also prepared under similar condition. These polymer solutions after direct dilution with DMSO were suitable enough to be applied to high strength fiber formation by dry-jet-wet spinning technique. Tensile strength was improved more than twice as high as that of common acrylic fiber used as apparel.

      • KCI등재

        교대제형태에 따른 지하철 남성 근로자들의 수면의 질과 관련요인

        김민기,이원철,이영민,유재홍,김환철,유승원,남경한 大韓産業醫學會 2008 대한직업환경의학회지 Vol.20 No.4

        배경 교번제 근무에 의해 지하철 근로자들의 수면의 질은 영향을 받고 있으나 기존 연구자체가 교번제를 행하는 지하철 기관사들만을 대상으로 하여 3교대 근로자 및 비교대 근무자의 수면의 질 점수와 수면장애군 분포의 차이를 비교할 수 없었고 수면에 영향을 끼치는 요인들을 파악할 수 없었다 이에 본 연구는 교번제와 3교대제 및 비 교대제 근로자들 간에 수면의 질의 차이가 있는지와 영향을 끼치는 요인들에 어떤 것들이 있는 지를 분석하기 위해 본 연구를 수행하였다 방법 2007년도 5월 초에 일개 지하철공사에 근무하는 모든 근로자를 대상으로 구조화된 설문지를 배포하였으며 2007년 5월말까지 회수되었다 회수된 설문지 중 수면의 질 평가설문지를 완벽히 기재하지 않은 70(6.93%)명과 그 수가 많지 않은 여성 근로자 36(3.56%)명을 제외한 759(75.15%)명의 남성 지하철근로자를 대상으로 설문분석을 시행하였다 자기기입식 설문지를 통하여 얻어진 자료를 SPSS (ver 12.0)프로그램을 사용하여 분석하였다 결과 교번제 근로자들이 직무요구와 직무불안정을 제외한 모든 직무스트레스점수 영역에서 가장 높은 점수를 차지하고 있으며 한국형직무스트레스 중앙값과의 비교에서도 교번제 근로자 중에서 직무스트레스 하부항목의 평균값 이상의 비율이 높았다 비교대 근무근로자들은 직무요구 직무불안정 항목에서 가장 높은 점수를 나타내었다 교대제에 따른 수면의 질 점수에서도 교번제 근로자들의 평균값이 5.1로 수면의 질 증상 점수인 5점을 넘고 있었으며 교대제에 따라 수면의 질 점수와 증상분포에 차이를 보였다 수면의 질은 직무요구가 높고 외적통제 신념이 강할수록 지난 1년간 아차사고를 경험하였거나 업무 중 사고를 경험하였을 때 나빠지며 비교대제 이거나 내적통제신념이 강할수록 좋아지는 결과를 보였다 결론 교번제에서 수면의 질 평균점수가 가장 높고 증상군의 비율도 가장 높았으며 직무스트레스의 대다수 항목에서 가장 높았다 지하철근로자들의 수면의 질 향상을 위해서는 교번제를 가급적 줄이는 교대제 체계의 개선 및 직무요구의 적절한 분배 내적통제신념 등의 향상과 사고 및 아차사고에 노출되는 교번제와 3교대 근로자들을 위한 사고 예방교육이 도움이 될 수 있을 것이다 Background The sleep quality of subway drivers who work in the dark underground with an rotating shift system is generally poor, which can degrade the quality of a worker's life This study examined the relationship between the sleep quality of subway worker and shift work by comparing three shift systems (rotating shift system, a three day shift system and no shift system). Method Questionnaires including The short form of the Korean Occupational Stress Scale (KOSS) Pittsburgh Sleep Questionnaire (PSQI), the worker's age gender job type, accident, near miss and shift system were given to a total of 1010 workers The results of 759 qualified questionnaires (75.15 %) were analyzed using the SPSS (ver 12.0) program. Result The highest level of job stress was found among those working a rotating shift system followed by three shift system and no-shift system. The mean sleep quality score in the rotating shift workers was 5.1 (SD±3.2), which was greater than the sleep symptom score (5) 34.8% of rotating shift workers suffered from sleep symptoms. The sleep quality score by shift-work was significantly different High job demand, strong external locus control, the experience of a near miss or an accident in the workplace during previous year has an adverse affect on the sleep quality The sleep quality improved in case of a change into a no-shift system or a strong internal locus control. Conclusion A rotating shift system is more harmful to the quality of sleep in subway workers than a 3 shift system or no-shift system. In addition, job stress, personality, near miss and the experience of an accident affect the sleep quality of subway workers.

      • 성인 급성 림프구성 백혈병에 대한 복합 화학 요법

        곽상혁,신현영,김성은,이정호,이정찬,강정현,윤환중,조덕연,김삼용 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.1

        Although acute lymphoblastic leukemia(ALL) is one of the most frequently encountered cancer in children, only about 20% of patients who were diagnosed leukemia are ALL in adults. During past 30 years, the result of treatment of ALL in children have been markedly improved, but in adults, the result of treatment of ALL is not so good as that in children. In recent, morbidity of ALL has been increased in KOREA, but studies of long-term survival are rare. So a retrospective clinical analysis was made in patients who were diagnosed for adult acute lymphoblastic leukemia between March 1988 and February 1997, in Chungnam National University Hospital. The result of treatment, prognostic factors of survival and duration of complete remission were analyzed. In 44 patients who were newly diagnosed as ALL in Chungnam National University Hospital, total 31 patients who have received chemotherapy more than two weeks were analyzed. All patients were treated by vincristine, daunorubicine, and prednisolone in phase I induction chemotherapy. At the 28th day of phase I induction chemotherapy, bone marrow aspiration biopsy was performed and achievement of complete remission was estimated. Within one or two weeks after completion of phase I chemotherapy, phase II induction chemotherapy was done. In phase II induction chemotherapy, cyclophosphamide, cytosine arabinoside and 6-mercaptopurine were administerd. During phase II induction chemotherapy, CNS prophylaxis with intrathecal methotrexate administration and intracranial irradiation. After completion of phase I and phase II of induction chemotherapy, 4 cycles of consolidation chemotherapy were made in utilization of VP-16 and cytosine arabinoside in standard risk group, and in utilization of methotrexate with leucovorin rescue and L-asparaginase in the high risk group. And then maintenance chemotherapy with 6-mercaptopurine and methotrexate was continued till two years later from the day of treatment start. The median survival time was 15.8 months (95% C.I. 6.0-18.8 months) and the long-term survival (more than 5 years after diagnosis) rate was 28.0%. The rate of complete remission was 83.9% ( 26 of 31) and the median of the complete remission duration was 15.8 months (95% C.I. 5.6-25.9 months). The rate of relapse was 69.2%. Good prognostic factor for overall survival time was the fraction of blast cells less than 75% in bone marrow at diagnosis (P=0.001) in univariate analysis. In multivariate analysis, age below 40 (P=0.003) and blast cells less than 75% in hone marrow at diagnosis (P=0.003) were good prognostic factors for overall survival time. Good prognostic factors for disease free survival in univariate analysis were the fraction of blast cells less than 75% in bone marrow (P=0.003), absence of fever (P=0.013), and absence of hepatomegaly (P=0.025), all at diagnosis. In multivariate analysis, good prognostic factors for disease free survival were platelet count more than 50,000/uL, blast cells less than 75% in bone marrow at diagnosis (P=0.004), serum LDH level below 500U/L (P=0.016). The result of treatment of ALL in adults has been improved but is not satisfactory in comparison with that in children. Despite of marked improvement of the rate of complete remission, the rate of relapse still not so much improved. So intensified consolidation chemotherpy or allogenic bone marrow transplantation or autologous bone marrow transplantation is necessary for improvement of survival of adult ALL.

      • 중독한 추체로 증상을 보인 cyclosporine에 의한 뇌증 1예

        강정현,곽승근,신현영,김성은,이정호,이정찬,곽상혁,윤환중,조덕연,김삼용,김제,송창준 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.1

        The use of cyclosporine(CsA), a potent immunosuppressive agent, is associated with numerous side effects. Neurotoxicity was earlier less well known, but with growing experience central nervous system side effects are now reported up to 40% of patients. Among various CsA-induced neurotoxicities, tremor is most common and posterior leukoencephalopathy is well characterized. An encephalopathy presenting with pyramidal weakness, however, seems to be rare and poorly documented. We report here a case of encephalopathy presenting with multiple generalized seizures followed by fluctuating quadriparesis developed a few days after starting CsA and resolved spontaneously after withdrawal of the drug . A 48-year-old woman with aplastic anemia was placed upon immmunosuppressive treatment consisting of antithymocyte globulin(ATG), CsA, and methylprednisolone. Two days after starting the therapy, she developed a generalized seizure. The next day she developed 2 more episodes of seizure and the therapy was stopped. Computed tomogram of the brain was normal. Six days after starting therapy, she developed mild motor weakness and paresthesia of both lower extremities, which progressed to a definite quariparesis confining her to a bed in 3 days. Magnetic resonance imaging(MRI) of the brain revealed asymmetric, bilateral high-signal abnormalites in the subcortical white matter of fronto-temporal areas. After reaching to a maximum with some fluactuation(14 days after starting the therapy) the motor weakness started to be resolved. She was discharged with a almost complete resolution of the weakness 45 days after starting the therapy. Five months later she did well and brain MRI was negative.

      • KCI등재

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