http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Genome-wide Linkage Study for Plasma HDL Cholesterol Level in an Isolated Population of Mongolia
Hansoo Park,김종일,Sung-Il Cho,Joohon Sung,Hyung-Lae Kim,Young Seok Ju,Gombojav Bayasgalan,이미경,서정선 한국유전체학회 2008 Genomics & informatics Vol.6 No.1
High-density lipoprotein (HDL) whose primary role is to transport cholesterol from peripheral tissues to the liver, is associated with the incidence of coronary heart disease. We analyzed HDL cholesterol levels in a genetically isolated population of extended Mongolian families. A total of 1002 individuals (54.5% women) from 95 families were enrolled. After genotyping by use of 1000 microsatellite markers, we performed a genome-wide linkage search with variance component analysis. The estimated heritability of HDL cholesterol was 0.45, revealing that HDL cholesterol was under significant genetic influence. We found peak evidence of linkage (LOD score=1.88) for HDL cholesterol level on chromosome 6 (nearest marker D6S1660) and potential evidences for linkage on chromosomes 1, 12 and 19 with the LOD scores of 1.32, 1.44 and 1.14, respectively. These results should pave the way for the discovery of the relevant genes by fine mapping and association analysis.
PYROPROCESSING TECHNOLOGY DEVELOPMENT AT KAERI
HANSOO LEE,GEUN-IL PARK,KWEON-HO KANG,허진목,JEONG-GUK KIM,DO-HEE AHN,YUNG-ZUN CHO,EUNG HO KIM 한국원자력학회 2011 Nuclear Engineering and Technology Vol.43 No.4
Pyroprocessing technology was developed in the beginning for metal fuel treatment in the US in the 1960s. The conventional aqueous process, such as PUREX, is not appropriate for treating metal fuel. Pyroprocessing technology has advantages over the aqueous process: less proliferation risk, treatment of spent fuel with relatively high heat and radioactivity,compact equipment, etc. The addition of an oxide reduction process to the pyroprocessing metal fuel treatment enables handling of oxide spent fuel, which draws a potential option for the management of spent fuel from the PWR. In this context, KAERI has been developing pyroprocessing technology to handle the oxide spent fuel since the 1990s. This paper describes the current status of pyroprocessing technology development at KAERI from the head-end process to the waste treatment. A unit process with various scales has been tested to produce the design data associated with the scale up. A performance test of unit processes integration will be conducted at the PRIDE facility, which will be constructed by early 2012. The PRIDE facility incorporates the unit processes all together in a cell with an Ar environment. The purpose of PRIDE is to test the processes for unit process performance, operability by remote equipment, the integrity of the unit processes, process monitoring, Ar environment system operation, and safeguards related activities. The test of PRIDE will be promising for further pyroprocessing technology development.
The Effect of Order-disorder Transition of SBS on the Performance Grade in PMA
Hansoo Park,Sunwoo Cheen,Jun Sang Park,Pil Sung Kim 한국도로학회 2018 한국도로학회 학술대회 발표논문 초록집 Vol.2018 No.05
The worldwide PMA pavement is steadily increasing. Unlike straight asphalt at the specified temperature of the performance grade, PMA has little increase in complex modulus after RFTO. Even after satisfying the complex modulus of the original binder, the complex modulus after the RTFO does not satisfy the grade, so that the SBS may be over-prescribed. Unlike straight asphalt, PMA investigated the reason that the complex modulus did not increase after RTFO in this study. SBS consists of a styrene domain and a butadiene matrix. The morphology of SBS in PMA is not clear. The PMA was heat - treated to induce the formation of styrene domain and PG evaluation was carried out. As a result, we confirmed that the formation of styrene domain with aging effect changed the complex modulus after RTFO.
Gaussian-Based SMOTE Algorithm for Solving Skewed Class Distributions
Hansoo Lee,Jonggeun Kim,Sungshin Kim 한국지능시스템학회 2017 INTERNATIONAL JOURNAL of FUZZY LOGIC and INTELLIGE Vol.17 No.4
Sufficient amount of learning data is an essential condition to implement a classifier with excellent performance. However, the obtained data usually follow a significantly biased distribution of classes. It is called a class imbalance problem, which is one of the frequently occurred issues in the real world applications. This problem causes a considerable performance drop because most of the machine learning methods assume given data follow a balanced distribution of classes. The implemented classifier will derive false classification results if the problem is not solved. Therefore, this paper proposes a novel method, named as Gaussianbased SMOTE, to solve the problem by combining Gaussian distribution in a synthetic data generation process. It is confirmed that the proposed method could solve the class imbalance problem by conducting experiments with actual cases.
Yubu Island, the Important Waterbird Habitat on the West Coast of Korea and Its Conservation
Hansoo Lee,이시완,백운기,Jeong-Yeon Yi,Hwa-Chung Kim 한국해양과학기술원 2002 Ocean and Polar Research Vol.24 No.1
Yubu Island is located within the estuary of the Geum River, South Chungcheong Province (35o59'N, 126o36'E), Korea. The island is surrounded by a broad and sandy mudflat, which is typical in the west coast of Korea, and is located 4 km off from Gunsan City. Less than 100 humans live on the island, occupying 30 houses. After we discovered that this island was a very important waterbird habitat especially for the East Asian subspecies of the Eurasian oystercatcher, Haematopus ostralegus osculans. Waterbirds were monitored once every month from August 1999 to July 2000. The highest number of oystercatchers counted was 3,200 in December 1999, and the birds seemed to remain in the area continuously from September to next February. About 200 breeding and non-breeding birds remained during the breeding season. In August, early migrants returned to the island, with the number reaching 1,060 individuals. This island is also very important for other waterbirds. Endangered or significant species occurring at this site, and their maximum counts were: chinese egret Egretta eulophotes (5), black-faced spoonbill Platalea minor (17), brant Branta bernicla (1), common shelduck Tadorna tadorna (8,000), hooded crane Grus monacha (2), spoon-billed sandpiper Eurynorhynchus pygmeus (7), dunlin Calidris alpina (6,500), great knot Calidris tenuirostris (24,000), far eastern curlew Numenius madagascariensis (2,500), spotted greenshank Tringa guttifer (4) and Saunders's gull Larus saundersi (1,200). During the 12 month survey period, we observed 52 waterbird species and the total of the maximum counts for the separate species was 73,308, implying that perhaps 150,000 birds could be using the immediate area, if a turnover rate of 2 was assumed.
Design and Fabrication of a Si PIN-type Radiation Detector for Alpha Spectroscopy
HanSoo Kim,SeHwan Park,JangHo Ha,조승연,KunSik Park 한국물리학회 2009 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.55 No.2
Silicon PIN-type radiation detectors, which have 4.5 kΩ·cm and 7 kΩ·cm resistivities, were designed and fabricated for alpha spectroscopy. The main design considerations of the Si PIN-type radiation detector were a high biasing voltage, a low leakage current, and a low alpha energy loss caused by the incident window of the p+ layer. Two guard electrodes and an edge protection structure were incorporated to minimize the leakage current and to apply a high bias voltage for full depletion. A shallow p+ layer and non-metal deposition on the p+ layer were also incorporated to minimize alpha energy loss. The doping profile of the p+ layer and the alpha energy loss due to p+ layer were approximately calculated by using a Silvaco device simulation tool kit and the SRIM code, respectively. About 7-nA reverse leakage current at a 200-V reverse bias voltage and an energy resolution a 1.1% for 5.5 MeV alpha particles were achieved with the fabricated Si PIN-type radiation detectors, which had two different resistivities. Several important aspects to consider in the fabrication of a Si PIN-type radiation detector are also addressed. Silicon PIN-type radiation detectors, which have 4.5 kΩ·cm and 7 kΩ·cm resistivities, were designed and fabricated for alpha spectroscopy. The main design considerations of the Si PIN-type radiation detector were a high biasing voltage, a low leakage current, and a low alpha energy loss caused by the incident window of the p+ layer. Two guard electrodes and an edge protection structure were incorporated to minimize the leakage current and to apply a high bias voltage for full depletion. A shallow p+ layer and non-metal deposition on the p+ layer were also incorporated to minimize alpha energy loss. The doping profile of the p+ layer and the alpha energy loss due to p+ layer were approximately calculated by using a Silvaco device simulation tool kit and the SRIM code, respectively. About 7-nA reverse leakage current at a 200-V reverse bias voltage and an energy resolution a 1.1% for 5.5 MeV alpha particles were achieved with the fabricated Si PIN-type radiation detectors, which had two different resistivities. Several important aspects to consider in the fabrication of a Si PIN-type radiation detector are also addressed.