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      • 신한옥 부재 제작을 위한 CNC 프로세스 적용 가능성에 관한 연구

        이현우(Lee Hyun-Woo),김미경(Kim Mi-Kyoung),이제진(Lee Je-Jin),전한종(Jun Han-Jong) 대한건축학회 2011 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.31 No.2(계획계)

        There have been a lot of studies about Han-Ok, the Korean-style house, in the perspective of existing Han-Ok’s inheritance, but there are no practicality in supply of Han-Ok. The cause is considered the complexity of Han-Ok construction techniques and higher construction expenses comparatively by processing in the restricted range by the shortage of the manufacturing technology of materials. On the contrary, for evolution to the new Han-Ok that can be supplied to the present period, there are studies that is analyzed the connection between sub materials and for possible modeling by formulating of assembling way. Thus, this study try to suggest the CNC process for new Han-Ok construction to secure construction relate to construction technique, which is determined by few expert technicians that is pointed out as problems of Han-Ok.

      • 한강시민공원 체육시설 현황과 효율적 활용 방안에 대한 연구

        한진욱,김진호 경희대학교 체육과학연구소 1999 體育學論文集 Vol.27 No.-

        The aim of this study is primarily to examine the current state of the sports facilities for the Han-Gang Citizens' Park and to propose its effective utilization plans for the coming 21st century. The main findings and conclusions can be described as follows: 1.Strengthening of publicity fucntions 2.To provide citizens with various means of easy access to the Park such as shuttle buses and samaul buses 3.Developments of new programs for the disabled and senior citizens 4.Extensive utlization measures for the evening hours 5.To make the Park distictive according to each distict 6.Reorganization of the Parks' administrative structures 7.Diversification of programs, and training and retaining instructors of an excellent caliber.

      • 범가자미, Verasper variegatus의 난황단백질 분리 및 면역학적 특성

        백혜자,한창희,김우진,박중연,김진한,김윤 동의대학교 기초과학연구소 1998 基礎科學硏究論文集 Vol.8 No.1

        The yolk protein of spotted flounder, Verasper variegatus was purified by precipitation with cold distilled water, followed by Sepharose CL-6B column chromatography. The purified protein was identified as vitellin by Ouchterlony's immunodiffusion test and immunoelectrophoresis. The purified vitellin from ovarian crude extracts has same antigenic determinants with the female specific serum protein, vitellogenin. The molecular weight of purified vitellin was estimated about 550kD by gel filtration. The vitellin was composed of three major subunits with molecular weight of about 108, 85 and 31 kD, and two minor subunits. The vitellin was identified by western blot analysis using anti-vitellin antibody.

      • KCI등재

        Four new compounds from the bulbs of Lycoris aurea with neuroprotective effects against CoCl2 and H2O2-induced SH-SY5Y cell injuries

        An Jin,Xuelian Xiang,Yun-Yun Zhu,Heng-Yi Yu,Hui-Fang Pi,Peng Zhang,Han-Li Ruan 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.3

        Three new alkaloids, 2a-hydroxy-6-O-n-butyloduline,O-n-butyllycorenine, (-)-N-(chloromethyl)lycoramine(1–3), and a new phenolic compound, ((7S)-7-(4-hydroxyphenyl)-7-hydroxypropyl)-20-methylbenzene-30,60-diol (14), along with ten known alkaloids (4–13), wereisolated from the bulbs of Lycoris aurea collected fromHuaihua County of Hunan Province, China. Their structureswere elucidated by spectroscopic methods includingHRESIMS, UV, IR, and NMR. All the isolated compoundswere tested for their neuroprotective effects against CoCl2and H2O2-induced SH-SY5Y cell death. Compounds 1–7and 10 exhibited significant neuroprotective effects againstCoCl2-induced SH-SY5Y cell injury, while compounds1–5, 7, 10 and 12 showed obvious neuroprotective effectsagainst H2O2-induced SH-SY5Y cell death.

      • KCI등재후보

        Anti-inflammatory and Anti-oxidant Effects of PHBV/Collagen (PHCP) on Lipopolysaccharide-Induced Skin Inflammation

        Jin-Yi Han3*, Xu Zi Guang, Jyung-Sik Kwak, Ki-Wan Oh, Han-Ik Bae 충북대학교 동물의학연구소 2012 Journal of Biomedical and Translational Research Vol.13 No.1

        The anti-inflammatory effect of PHBV/Collagen (PHCP) was examined in a mouse model of lipopolysaccharide (LPS)-induced skin inflammation. Vascular permeability on the back skin was measured by the local accumulation of Evan’s blue dye after subcutaneous injection of LPS (30 μg site-1). Dye leakage in the skin showed a significant increase at 2 h after injection of LPS. This LPS-induced dye leakage was also completely inhibited by HO-1 inhibitor, ZnPP, and antioxidants, including methyl gallate, trolox, and mannitol. To study the possible mechanisms underlying the in vivo anti-inflammatory effect of PHCP against LPS-induced inflammation, we also examined the effects of PHCP on malondialdehyde (MDA) and glutathione levels in skin tissues and found that pretreatment with PHCP resulted in inhibited MDA elevation and a remarkable reduction of glutathione level. In addition, similar results were obtained after pretreatment with antioxidants, including trolox and mannitol, and HO-1 inhibitor, ZnPP. Histopathologically, an influx of neutrophils into the skin dermis was detected between 24 h and 72 h after LPS injection (30, 100 μg site-1), compared to control animals after injection of saline. This increase was greater in mice treated with 100 μg of LPS than in those treated with 30 μg of LPS and was significantly suppressed by pretreatment with PHCP, antioxidants, and HO-1 inhibitor. These results collectively suggest that PHCP has an anti-inflammatory effect against LPS-induced inflammation model in vivo and may be a good candidate for the skin tissue engineering biomedical application primarily through manipulation of the redox state.

      • KCI등재

        Research Trends in Young Children’s Theory of Mind using Keyword Network Analysis

        Han,Yoo-Jin(Yoo-Jin Han),Kim,Ho(Ho Kim) 경인교육대학교 교육연구원 2022 교육논총 Vol.42 No.-

        This study aims to investigate the trends in research and find implications for future research to understand the characteristics of young children’s theory of mind from 1997 to 2021. Out of the research papers published in journals in the field of early childhood education, 175 articles that fit the purpose of this study were analyzed using network analysis methods. The summary of the analysis results was as follows: First, in the study of young children’s theory of mind, “theory of mind”, “false belief”, “pretend play”, “emotion”, “executive function”, “social ability”, “story”, “young children”, “peer competence”, and “picturebook” showed high frequency. Second, it can be seen that the network structure for each period gradually changes from the first to the third periods. This demonstrated that while the research of theory of mind was somewhat slow but steadily active, the keywords identified in the early childhood theory of mind study evolved into a broad and rich array. Based on the results of this study, this study suggests diversification of the theory of mind research to perspectives of social cognition development of young children.

      • KCI등재

        Differential Manifestation of Ocular Phenotypes in TALEN-mediated p19arf Knockout FVB/N and C57BL/6J mouse lines

        Jin‑Sung Park,Joo‑Il Kim,Hyun‑Jin Lim,Soo‑Kyung Ryu,Euna Kwon,Kang‑Min Han,Ki‑Taek Nam,Han‑Woong Lee,Byeong‑Cheol Kang 한국유전학회 2020 Genes & Genomics Vol.42 No.9

        Background p19arf, primarily known as a tumor suppressor, has also been reported to play an essential role in normal development of mouse eyes. Consistently, lack of p19arf has been associated with ocular defects, but the mixed background of the knockout (KO) mouse strain used raised a concern on the accuracy of the phenotypes observed in association with the targeted gene due to genetic heterogeneity. Object We carried out a study to investigate into the efect of genetic background on the manifestation of p19arf KO associated phenotypes. Methods We characterized the phenotypes of novel p19arf KO mouse lines generated in FVB/N and C57BL/6J using a transcription activator-like efector nuclease (TALEN) system in comparison to the reported phenotypes of three other p19arf-defcient mouse lines generated using homologous recombination. Results Ninety-fve percent of FVB/N-p19arf KO mice showed ocular opacity from week 4 after birth which worsened rapidly until week 6, while such abnormality was absent in C57BL/6J-p19arf KO mice up to the age of 26 weeks. Histopathological analysis revealed retrolental masses and dysplasia in the retinal layer in FVB/N-p19arf KO mice from week 4. Besides these, both strains developed normally from birth to week 26 without increased tumorigenesis except for a subcutaneous tumor found in a C57BL/6J-p19arf KO mouse. Conclusion Our fndings demonstrated surprisingly variable manifestation of p19arf-linked phenotypes between FVB/N and C57BL/6J mice, and furthermore between our mouse lines and the established lines, indicating a critical impact of genetic background on functional study of genes using gene targeting strategies in mice.

      • 정지궤도 위성과 지구국간 광통신 링크의 전송속도 해석

        한종석,정진호,김영권,Han, Jong-Seok,Jung, Jin-Ho,Kim, Yung-Kwon 한국전기전자학회 1997 전기전자학회논문지 Vol.1 No.1

        정지궤도 위성과 지구국간 광통신을 대기상태와 앙각의 함수로써 해석할 수 있는 한모델(Han's model)을 제시하였다. 한모델에서는 대기상태를 맑은날, 구름낀 날, 안개, 헤이즈, 비, 눈의 여섯가지 전형적인 상태로 구분한다. 비트오류을 $10^{-7}$을 만족하는 데이터 전송속도를 한모델을 이용하여 상향링크와 하향링크에 대해 해석하였다. 상향링크시의 포인팅손실이 하향링크시의 대기에 의한 공간 가간섭 저하보다 크기 때문에 데이터 전송속도는 하향링크 보다 오히려 상향링크시에 제한됨을 알 수 있었다. Han's model, which is able to analyze optical communication between earth station and geo-satellite as a function of atmospheric conditions and elevation angles. is presented. In Han's model, atmospheric conditions are roughly classified into six basic types; clear sky, cloud, haze, fog, rain and snow. Data rate satisfying for the BER below $10^{-7}$ is analyzed by Han's model in case of up-link and down-link, respectively. Data rate is more limited by up-link than by down-link because the pointing loss caused by atmosphere on the up-link is greater than the spatial coherence degradation caused by atmosphere on the down-link.

      • SCOPUSKCI등재

        Cleidocranial dysplasia : a case report

        Han, Jin-Woo 대한구강악안면방사선학회 2005 Imaging Science in Dentistry Vol.35 No.4

        Cleidocranial dysplasia is a rare, autosomal dominant congenital disorder. A 12-year old female visited with chief complaint of unerupted permanent teeth. Also her father showed severe class Ⅲmalocclusion. The extraoral radiography and computed tomography showed delayed closure of the cranial sutures and underdevelopment of maxilla, maxillary sinuses, and frontal sinus. Both clavicles were underdeveloped and thoracic rib cage was bell-shaped. Both zygomatic process appeared as hypoplastic feature. There were many unerupted permanent and supernumerary teeth in the maxilla and mandible. We examined location and number of the unerupted teeth using 3D CT. Finally we could conclude this case was cleidocranial dysplasia based on the clinico-radiologic findings.

      • KCI등재

        특허 정보를 활용한 컨버전스 산업에서의 경쟁 관계 분석 : 텔레매틱스의 예

        한유진 ( Yoo-jin¸ Han ) 한국지식재산연구원 2006 지식재산연구 Vol.1 No.2

        Recently, technological convergence has been paid much attention to in various fields. However, it has not been easy for firms to analyze the competition structure due to the vague characteristics of a convergence industry. Therefore, in this research, by using patents, I explore how firms can frame strategies in the fields wherein strategists suffer difficulties in defining competitors. To this end, a firm-wise technology portfolio and inter-firm technology portfolio similarity map will be prepared. As an example for a convergence industry, telematics is selected and among the patents granted by respective governments, US patents are used. The sample is composed of 363 patents corresponding to 40 companies and 36 technological fields. It was found that two company pairs had the exact same technology portfolios and three companies possessed unique technology portfolios. According to the similarities between these portfolios, appropriate technology strategies were proposed. Although the example of telematics may not be perfectly matched to other industries, the exploration process above will be a useful step for shaping technology strategy in a high-tech convergence industry.

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