모성으로 구축하는 여성 택견의 새로운 패러다임에 관한 탐색

김영학,장경태,김태일,허채봉 龍仁大學校 武道硏究所 2011 武道硏究所誌 Vol.22 No.1

여성택견연맹은 택견의 최고지도자가 택견미래를 위한 포석으로 창설을 주도한 것이다. 그런 만큼 연맹의 기능과 역할에 거는 택견전체의 기대가 큰 것을 알 수 있다. 그럼에도 연맹은 그 기대에 부응하지 못하고 조직 자체의 존폐가 위기에 몰렸던 것도 사실이다. 이제 새로 출범하는 제2기 연맹은 회장을 중심으로 외견상으로 볼 때 탄탄한 진용임이 분명하다. 집행부의 임원 한 사람 한 사람의 면면을 보면 충분히 수긍이 간다. 다시 말해 인적자원은 충분하다는 뜻이다. 문제는 이 인력을 얼마나 활용하느냐 하는 것이라고 생각된다. 지난 날 잘 한 것을 계승하여 더욱 활성화하고 부족했던 부분을 보완하고 개선하면 될 것이다. 앞서 살펴본 바와 같이 모든 문제의 시작과 결과는 여성택견인들의 참여의식의 여부에 달려 있다고 판단된다. 우리 연맹이 정체된 것도 따지고 보면 바로 우리 각자의 이기주의적․편의주의적 의식에 기인하는 것이라고 생각한다. 공동체적 가치를 지향할 때 인간은 인간다워진다는 것이 보편적 진리이다. 이를 모를 사람은 없을 것이다 그런데 알면서도 이를 실행하지 못하는 것이 어려운 문제인 것이다. 택견 내부의 공동체적 가치구현을 우리 여성연맹 구성원들이 지닌 모성적 이타주의로 이끌어 나간다면 여성연맹의 기능은 활성화될 것이다.

축하중과 첨가질량이 작용하는 적층복합판의 진동해석

이봉학,김경진,원치문,성기태 江原大學校 産業技術硏究所 1995 産業技術硏究 Vol.15 No.-

A method of calculating the natural frequency corresponding to the first mode of vibration of beams and tower structures, with irregular cross-sections and with arbitrary boundary conditions was developed and reported by D. H. Kim in 1974. IN this paper, hte result of application of this method to the laminated plates with axial forces and with attached point mass/masses is presented. Both N? and N? forces are considered. The solution for the laminated plates with arbitrary boundary conditions and irregular section can be obtained by simply obtaining the deflection influence coefficients by any method. The effect of neglecting the mass of the plates on the natural frequency, as the ratio of the point mass/masses to the plate mass increases, is thoroughly studied. The influence of N? and N? is also carefully investigated.

Single-Chip 마이크로 콘트롤러를 이용한 이상 전류 검출기

김경렬,나채동,문학룡,유두영 崇實大學校 生産技術硏究所 1993 論文集 Vol.23 No.-

The development of the measurement technology has occupied an important position of not only the electrical, electronic but also scientific technology sphere. In the past, the abnormal current detector was used by the analog method, had many the trouble and the inconvenience of measurement, dissatisfied the accuracy and had difficulty in storing, preserving the data. In this paper, these are improved by using single-chip microcontroller which detects the abnormal current and saves in back-up RAM after digitizing. For the efficient management, processing of the memory, it was used the index method. The data in the memory can be transmitted to the personal computer by the serial communication, and also be independently transmitted by the parallel communication to the personal computer which is interfaced with. The software to control system components are structured in assembly language and C language, in order to process and analyze the software is used in C language.

건강식품 바이탈 및 비지놀의 抗疲勞 效果에 관한 연구

정경수,김혜경,김희수,김계양,곽영숙,김학범 충남대학교 약학대학 의약품개발연구소 1993 藥學論文集 Vol.9 No.-

As a result of extensive research efforts on the oriental medicinal herbs, some of their interesting biological activities have been elucidated. In the present study, antifatigue effects of two natural food supplements consisting of oriental herbs, Vital and Vigilor, were investigated using the ICR mice. The mice were fed with antibiotic-free normal mouse feed containing Vital or Vigilor for 14,28, or 31 days and then subjected to forced swim tests. In a test carried out in melting-ice water, Vital and Vigilor significantly increased the exhaustion times of the 28 day-fed mice by 26.9 % (p < 0.01) and 16.2% (p < 0.05), respectively. However, in the other test performed at 15±0.5℃ using 31 day-fed mice, Vigilor failed to increase the exhaustion time significantly (at p< 0.05), while Vital showed antifatigue effect by increasing the swimming time by 29.9% (p<0.01). Neither of Vital nor Vigilor exerted antifatigue effects in a swim test carried out on day 14 after the initiation of feeding. These results suggest that Vital and Vigilor exhert antifatigue effets when administered for a sufficient period of time by enhancing the health of the host animals.

Rat의 복강에 삽입한 Fluorouracil-Polyglycolic acid 제형의 Fluorouracil 용출에 관한 연구

노승무,정경수,오정연,김진향,양준묵,강대영,송규상,최정목,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 忠南大學校 癌共同硏究所 1998 癌共同硏究所 硏究誌 Vol.2 No.1

A common form of relapse in adenocarcinoma of the stomach is intraperitoneal dissemination, in fact, among gastric adenocarcinoma patients who have undergone surgery intended to cure, approximately 50% of the patients develope initial recurrence in the peritoneal cavity regardless of the anatomic site of the primary tumor within the stomach. The efficacy of systemic postoperative chemotherapy to prevent peritoneal recurrence of gastrric adcnocarcinoma is not satisfactory. There is still a great need for improved therapeutic strategies on the disseminated microscopic disease and small miliary nodules remaining on the peritoneal surface or lymphatics after operation. The authers have made fluorouracil-polyglycolic acid composite disks(Fu-PGA disks) with fluorouracil and biodegradable polymer: polyglycolic acid for more effective intraperitoneal chemotherapy. We inserted the Fu-PGA disk(s) in the peritoneal cavity of rat and pharmacokinetic study was performed to measure fluorouracil concentration in the peritoneal fluid, plasma, liver, kidney and heart tissue at 24 hour, 72 hour and 168 hour after insertion of Fu-PGA disk(s). Myelosuppressive action of this composite also was determined following its administration. The data of this study suggested that Fu-PGA composite will be a new device releasing drugs in a controlled manner and having targetability to peritoneum, and this device will be improving the efficacy of intraperitoneal chemotherapy for gastric adenocarcinoma.

Rat의 복강에 삽입한 Filorouracil-Polyglycolic acid제형의 Fluorouracil용출에 관한 연구

노승무,정경수,오정연,김진향,양준묵,강대영,송규상,최정목,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

A common form of relapse in adenocarcinoma of the stomach is intraperitioneal dissemination, in fact, among gastric adenocarcinoma patients who have undergone surgery intended to cure, approximately 50% of the patients develope initial recurrence in the peritoneal cavity regardless of the anatomic site of the primary tumor within the stomach. The efficacy of systemic postoperative chemotherapy to prevent peritoneal recurrence of gastrric adenocarcinoma is not satisfactory. There is still a great need for improved therapeutic strategies on the disseminated microscopic disease and small miliary nodules remaining on the peritoneal surface or lymphatics after operation. The authers have made fluorouracil-polyglycolic acid composite disks(Fu-PGA disks) with fluorouracil and biodegradable polymer: polyglycolic acid for more effective intraperitoneal chemotherapy. We inserted the Fu-PGA disk(s) in the peritoneal cavity of rat and pharmacokinetic study was performed to measure fluorouracil concentration in the peritoneal fluid, plasma, liver, kidney and heart tissue at 24 hour, 72 hour and 168 hour after insertion of Fu-PGA disk(s). Myelosuppressive action of this composite also was determined following its administration. The data of this study suggested that Fu-PGA composite will be a new device releasing drugs in a controlled manner and having targetability to peritoneum, and this device will be improving the efficacy of intraperitoneal chemotherapy for gastric adenocarcinoma.

주야교대작업이 근로자의 심혈관계 질환의 위험인자에 미치는 영향

신재학,이중정,이경수,사공준,김창윤,정종학 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.1

지속적인 주야간 교대작업이 심혈관계 질환의 위험요인에 미치는 영향을 평가하고, 심혈관계 질환의 위험요인들 중 교대작업에 의해 민감하게 영향을 받는 요인들을 조사하고, 교대작업에 참여한 기간과 위험요인들과의 관계를 평가하기 위하여 울산시에 있는 모 자동차공장 생산직 근로자를 대상으로 1993년 4월 20일부터 2개월간에 걸쳐 단면조사를 시행하였다. 교대작업은 하루 2교대로 이루어지며 야간작업조와 주간작업조는 1주일 주기로 순환되었다. 근무기간 1년이상 80%이상을 교대작업에 참여했던 근로자 420명을 교대작업군으로, 교대작업에 참여한 경험이 전혀 없는 생산직 근로자 88명을 대조군으로 하여 연령, 성별, 최종 학력, 현 산업장에서의 근속기간, 입사전 경력, 현재 작업부서, 작업내용 및 직급을 자기기입식 설문지를 통하여 조사하였다. 교대작업에 관해서는 조사당시의 교대작업에 참여여부, 교대작업의 주기와 규칙성 여부, 입사후 지금까지 교대작업에 참여한 기간을 조사하였다. 심혈관계 질환의 위험요인들로서 혈압, 콜레스테롤치, 중성지방, apolipoprotein A-1과 B 등을 측정하였다. 위험요인들의 단순비교에 있어서는 수축기혈압은 교대작업군과 대조군이 각각 122.4±11.9mmHg, 120.0±11.4mmHg로 교대작업군에서 다소 높았고 이완기혈압도 각각 76.5±9.3mmHg, 75.9±9.1mmHg로서 교대작업군에서 다소 높았으나 유의한 차이는 없었다. 콜레스테롤치와 중성지방도 교대작업군에서 다소 높았으나 통계적으로 유의하지 않았다. Apolipoprotein B는 교대작업자가 101.8±19.9mg/dl로서 대조군의 94.2±26.5mg/dl에 비해 다소 높게 나타났으며 통계적으로도 경계역 유의성을 보였으나(p=0.057), apolipoprotein A-1은 apolipoprotein B에 비해 개인적인 변이가 크고 두 군간의 차이를 인정할 수 없었다. Apolipoprotein B와 apolipoprotein A-1의 비는 교대작업군이 0.73±0.20으로 대조군에 비해 높게 나타났다(p<0.05). 비체중은 두 군 모두 약 22로서 유의한 차이를 보이지 않았으나, 1주일 동안 규칙적인 운동을 하는 횟수는 대조군이 1.27±1.5회에 비해 교대작업자가 0.76±1.1회로서 유의하게 적었다(p<0.01). A형 행동양상을 가지는 비율은 교대작업자에서 58.8%로 주간작업자의 51.1%에 비해 다소 높았으나 통계적으로 유의하지는 않았다. 심혈관계 질환의 주된 위험인자들을 종속변수로 하고 교대작업과 다른 위험인자들을 독립변수로한 다중회귀분석에서는 수축기혈압을 종속변수로 채택하였을 때 가변수 교대작업은 회귀계수 2.668로서 수축기혈압을 증가시키는 것으로 나타났으며 (p=0.059), 비체중도 경계역 유의성을 보였다(p=0.053). 이완기혈압에 대한 다중회귀분석에서는 가변수인 교대작업이 유의한 영향을 미치지 않은 것으로 나타났으며, 비체중이 유의한 변수였다(p<0.01). 콜레스테롤치를 종속변수로 하여 실시한 다중회귀분석의 결과는 연령 및 비체중이 증가할수록 콜레스테롤치가 증가하는 경향을 보였으며 가변수인 교대작업이 콜레스테롤치를 증가시키나 통계적으로 유의하지는 않았다. 중성지방에 대한 다중회귀분석에서는 가변수 교대작업이 중성지방을 증가시키는 것으로 나타났으나 통계적으로 유의하지는 않았다. Apolipoprotein A-1의 경우 가변수 교대작업은 apolipoprotein A-1의 수준을 감소시키는 경향을 보였으나 통계적으로 유의하지는 않았다. 그 밖의 다른 변수들 중 apolipoprotein A-1의 수준에 영향을 미치는 변수는 없었다. Apolipoprotein B를 종속변수로한 다중회귀분석에서는 가변수 교대작업은 apolipoprotein B의 수준을 증가시키는 경향을 보였으나 통계적으로 유의하지는 않았다. Apolipoprotein B와 apolipoprotein A-1의 비를 종속변수로 한 다중회귀분석에서는 가변수 교대작업이 apolipoprotein B/Apo A-1을 증가시키는 변수였으며 통계적으로도 유의하였다(p<0.05). 교대작업군을 교대작업에 참여한 기간이 5년 미만인 군과 5년 이상인 군으로 나누어 비교하였을 때 콜레스테롤치, apolipoprotein B 및 Apo B/Apo A-1가 5년 미만의 교대작업군에 비해 5년 이상인 군이 유의하게 높게 나타났다(p<0.05). 교대작업기간이 위험요인에 미치는 영향을 보기 위해 가변수로 교대작업기간을 독립변수로 투입하여 다중회귀분석을 실시하였다. 콜레스테롤치를 종속변수로 한 다중회귀분석에서는 교대작업의 기간이 길수록 유의하게 증가하는 경향을 보였으며(p<0.05), apolipoprotein B도 교대작업의 기간이 길수록 다소 증가하는 경향을 보였으나 통계적으로 유의하지는 않았다. An investigation of effects of shift work on cardiovascular risk factors has been carried out on workers of a motor company in Ulsan, for 2 months from 20 April to 20 June, 1993. This cross-sectional survey was designed to compare the shift workers(n=420) with day workers(n=88). The study subjects were drawn from workers who were employed in twelve hour shift system. A control group who never experienced shift work was drawn from different sections of the factory. Each worker completed a medical and occupational questionnaire, and cardiovascular risk factors such as blood pressure, total cholesterol, triglyceride, apolipoprotein A-1 and B were measured. In univariate analysis, apolipoprotein B and the ratio of apolipoprotein B to apolipoprotein A-1 increased in shift workers. In multiple regression analysis for the systolic blood pressure, shift work was significant independent variable(p=0.059). In multiple regression analysis for the cholesterol, age and body mass index were significant independent variables(p<0.01), but shift work was not a statistically significant independent variable. In multiple regression analysis for the ratio of apolipoprotein B to apolipoprotein A-1, shift work was significant independent variable(p<0.05). Shift workers who have engaged in shift work more than 5 years have an excess of total cholesterol, apolipoprotein B and ratio of apolipoprotein B to apolipoprotein A-1 than those who have engaged in shift work less than 5 years (p<0.05). In multiple regression analysis for the cholesterol, duration of shift work was a significant independent variable(p=0.012). In multiple regression analysis for the apolipoprotein B and ratio of apolipoprotein B to apolipoprotein A-1, duration of shift work was not a significant independent variable.

위암환자의 복강내에 투여한 Mitomycin C-Carbon Particle의 Mitomycin 용출에 관한 연구

노승무,조영훈,정경수,오정연,김진향,양준묵,강대영,송규상,조준식,최선웅,이진호,민병무,김용백,김창식,박근성,인현빈,정현용,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherpy seems a logical choice for cancer chemotherapy. The Mitomycin C(MMC) adsorbed by the activated charcoal particles(CH) is relatively released when the drug concentration surrounding the carbon particles becomes low in the peritoneum of the peritoneal cavity. For the intraperitoneal chemotherapy on the advanced gastric adenocarcnoma, mitomycin C adsorbed on activated carbon particles was administered in the peritoneal cavity just before abdominal wall closure. The closed drainage tubes were inserted in the peritoneal cavity and clamped for tuo hours after completion of operation. MMC concentrations were serially measured in peritoneal fluid, plasma and urine at 2hour, 48 hour, 72 hour and 168 hour following its administration in order to study the efficacy of the MMC-CH as a drug delivery system. There were minimal toxicities in born marrow, liver, and gastrointestinal system after intraperitoneal MMC-CH administration. The data of this study suggested that MMC-CH may have a somewhat more beneficial effect than surgery alone when administered in optimal dose and schedules, but the MMC concentration of the peritoneal fluid was not sufficient to eradicate remnant cancer cells, and effective duration of maintenance was only below 24 hours in the peritoneal fluid and plasma.

위암 환자의 복강내 투여를 위한 Activated Charcoal-Alginate Bead 제형으로부터 Mitomycin C의 용출 거동

이진호,최선웅,서중기,김동민,정경수,오정연,김진향,노승무,민병무,김용백,김창식,박근성,강대영,송규상,양준묵,조준식,정현용,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherapy seems a logical choice for cancer chemotherapy. In this study, Mitomycin C (MMC)-activated charcoal (CH)-alginate (ALG) beads were prepared by the mixtures of CH particles adsorbed with MMC as an anti-cancer drug and aqueous alginate solution. The alginate is recognized as biodegradable, nontoxic, and biocompatible. The release of MMC from the beads in 0.1 M Tris buffer was stable and continuous until about 1 week. The MMC-CH-ALG beads can be applied in the peritoneal cavity for intraperitoneal chemotherapy since they provide a good adhesiveness on the tissue and controlled release pattern of the drugs.

Rat의 복강내에 투여한 5-fluorouracil-polyglycolic acid 제형이 장기에 미치는 영향에 관한 연구

강대영,송규상,최정목,노승무,정경수,오정연,김진향,양준묵,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

For more effective intraperitoneal chemotherapy, the authers made 5-fluorouracil-polyglycolic acid composite disks(FU-PGA disks) with 5-fluorouracil and polyglycolic acid, a biodegradable polymer. We inserted the FU-PGA disk into the peritoneal cavites of Sprague-Dawley male rats, the control and three experimental groups; one FU-PGA disk insert group(300mg/kg), two FU-PGA disk insert group(600mg/kg), and three FU-PGA disk insert group(900mg/kg). The control group received a similar number of PGA disk inserts. A pharmacokinetic study was performed to measure the 5-fluorouracil concentration in the peritoneal fluid, blood, and tissues(liver, kidney and heart) at 24 hours, 72hours and 168 hours after insertion of the FU-PGA disk. Light and electron microscopic studies were done. The results were as follows: 1) The number of white blood cells and platelets decreased after FU-PGA insertion. The degree was proportional to the duration and amounts inserted. The change in the number of red blood cells varied slightly. 2) Light microscopically, slight changes were noted at 168 hours in the 3 disk insert group (900mg/kg). Mild fatty change and hepatocyte degeneration around the central veins of the liver were noted, with vacuolar degeneration in the proximal convoluted tubules of the kidney. 3) Electron microscopically,the liver showed focal increases of lipid droplets in the hepatocytes, and irregular nuclear membrane with focal nucleolar segregation of the fibrillar and granular elements. Also the double membranous structure of the hepatocytes and Kupffer cells was widened with bleb formation. The kidney showed wide separation of the nuclear double membrane in the proximal convoluted tubular cells and mesangial cells, with vacuolation and myelin figure formation in the mitochondria of the proximal convoluted tubular cells, at 72 hours and 168 hours in the 2 to 3 FU-PGA insert groups. The heart showed focal loss of cristae,vacuolation and myelin figure formation in the mitochondria of the 2 to 3 FU-PGA insert groups. In conclusion, despite the large amont of FU-PGA inserted, the histopathological changes in the liver, kidney and heart were slight, and consonant with the very low amount of 5-fluorouracil concentrations detected in the liver, kidney and heart. The above results suggest that the FU-PGA composite can serve as a new device for releasing drugs in a controlled manner and easily targeted to intraperitoneal organs. This device can improve the efficacy of intraperitoneal chemotherapy for gastric cancer.