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      • 국민학교 영어 교육 실례 연구(Ⅰ)

        이혜란 淑明女子大學校 1983 論文集 Vol.24 No.-

        There are pros and cons involved in the issue of teaching English in our elementary schools. Some English educators strongly argue that our children should be taught English, before they reach the critical period (11∼12) when their pronunciation will have no hope to be like that of native speakers. On the other hand, some observe that teaching English in our elementary schools is rather untimely because of the lack of teaching materials capable teachers, facilities, etc. There have been quite a few theses representing both sides. Despite these heated debates or perhaps because of them, the Ministry of Education decided in October 1981 to enforce teaching English in elementary schools beginning March of 1982 through extra curricular activities or English classes. Almost a year and half has passed since then. However, there are no reports available from field experiments. This study reports the experiment with 6th graders in a private elementary school from March of 1982 to February of 1983 (26 weeks). It was conducted emphasizing listening and speaking. It decribes the experimental study in six areas: pronunciation, sentence structure, communication skills, vocabulary, reading and writing of the Alphabet, and motivation. It concludes that 6th grade children are ready and eager to receive English education. The results of teaching English to them testify that communication skills improve significantly while motivation remains high. Because this study is only the first step of its kind, it is encouraged and expected that professionals in English education pursue the topic through other experiments, studies, research and written articles. In this way only can we discover the most efficient and timely method of teaching and learning the English language in our elementary schools.

      • KCI등재
      • Rapid Measurement of NH<sub>3</sub> and Weak Acid Permeation Through Liposomes and Renal Proximal Tubule Membranes

        Bae. Hae-Rahn,Suh. Duck-Joon,Lee. Sang-Ho 대한생리학회 1994 대한생리학회지 Vol.28 No.2

        Using the methods of stopped-flow and epifluorescence microscopy with entrapped fluorophore, membrane permeability of NH<sub>3</sub> and weak acids in liposomes, renal brush border (BBMV) and basolateral membrane vesicles (BLMV), and primary culture cells from renal proximal tubule was measured. Permeability coefficient (cm/sec) of NH<sub>3</sub> was (2.9 X 10<sup>-2</sup> in phosphatidylcholine liposome 25℃), 5.9 X 10<sup>-2</sup> in renal proximal tubule cell (37℃), 4.0 X 10<sup>-2</sup> and 2.4 X 10<sup>-2</sup> in BBMV and BLMV (25℃), respectively. Formic acid has the highest permeability coefficient among the weak acids tested, which was 4.9 X 10<sup>-3</sup> in liposome, 5.0 X 10<sup>-3</sup> in renal proximal tubule cell, 9.1 X 10<sup>-3</sup> in BBMV and 3.8 X 10<sup>-3</sup> in BLMV. There was a linear relationship between external concentration of nonionized formic acid and initial rate of flux of formic acid in liposome, and the slope coincided with the value of permeability coefficient of formic acid measured in pH 7.0. These results show that techniques of stopped-flow and epifluorescence microscopy with entrapped fluorophore provide the precise method of measurement of very rapid transport of nonelectrolytes through membranes with the advantages of instantaneous mixing effect, good resolution time and easy manipulation.

      • Analytical Reading Skills : What, Why, How?

        Lee, Hae-Rahn 淑明女子大學校 1986 論文集 Vol.27 No.-

        인류문화의 발전과 지식의 보급을 위해서는 문자의 이해가 중요하며 읽기능력의 우열은 생존경쟁과도 직결된다. 적절한 읽기능력의 교습이 없이는 개개인의 인간성을 위한, 평등주의에 입각한 민주사회 건설을 위한 교육목표를 달성할 수 없다. 본고에서는 1955, 1963, 1974, 1981년에 문교부령으로 제정공포된「국어과」와 「외국어과」교육과정의 고등학교 3학년 학습지침에서 「읽기」면 만을 살펴 보았다. 조사에 의하면 과거 20여년간 국어과나 영어과의 교과과정에 있어서 「읽기」교습 면에 별다른 발전이 없고, 지도목표나 지도법이 구체적이고 체계적으로 명시되어 있지 않다. 즉 학생들이 논리적·비평적 사고력을 가지고 읽는 능력을 신장시킬 수 있도록 하는 지도방안이 설정되어 있지 않다. 본고에서는 이를 보완하여 독서능력증진 방안으로 분석적·비평적 독서력 교수를 제안하고, 「읽기」교수법을 구체적으로 제시하였다.

      • Rapid Measurement of $NH_3$ and Weak Acid Permeation Through Liposomes and Renal Proximal Tubule Membranes

        Bae, Hae-Rahn,Suh, Duck-Joon,Lee, Sang-Ho The Korean Physiological Society 1994 대한생리학회지 Vol.28 No.2

        Using the methods of stopped-flow and epifluorescence microscopy with entrapped fluorophore, membrane permeability of $NH_3$ and weak acids in liposomes, renal brush border (BBMV) and basolateral membrane vesicles (BLMV), and primary culture cells from renal proximal tubule was measured. Permeability coefficient (cm/sec) of $NH_3$ was $(2.9{\times}10^{-2}$ in phosphatidylcholine liposome $25^{\circ}C)$, $5.9{\times}10^{-2}$ in renal proximal tubule cell $(37^{\circ}C)$, $4.0{\times}10^{-2}\;and\;2.4{\times}10^{-2}$ in BBMV and BLMV $(25^{\circ}C)$, respectively. Formic acid has the highest permeability coefficient among the weak acids tested, which was $4.9{\times}10^{-3}$ in liposome, $5.0{\times}10^{-3}$ in renal proximal tubule cell, $9.1{\times}10^{-3}$ in BBMV and $3.8{\times}10^{-3}$ in BLMV. There was a linear relationship between external concentration of nonionized formic acid and initial rate of flux of formic acid in liposome, and the slope coincided with the value of permeability coefficient of formic acid measured in pH 7.0. These results show that techniques of stopped-flow and epifluorescence microscopy with entrapped fluorophore provide the precise method of measurement of very rapid transport of nonelectrolytes through membranes with the advantages of instantaneous mixing effect, good resolution time and easy manipulation.

      • KCI등재
      • KCI우수등재
      • 독해에 영향을 미치는 배경 요인 연구

        이혜란 淑明女子大學校 1993 論文集 Vol.33 No.-

        This paper studies some factors which may influence reading comprehension. Among many possible factors, it focuses on the background of the reader, especially on the reader's schemata (prior experiences) and cultural knowledge. This study examines related studies and previous experimental work. They assure us that reading comprehension utilizes a reader's prior experiences as well as his cultural knowledge. The reader has to have schemata which are appropriate for the reading material. Reading coprehension is a process of interaction between the reader's knowledge and the content of the passage. Therefore. the teacher should provide the reader with related background knowledge prior to reading in order to aid the student in comprehending the passage properly. In addition to the student's prior knowledge of the subject. i.e., knowledge of the world and a(fictive factors, the teacher must add information on the socio-cultural heritage of the reading material. This study concludes that the reader's background. his proper schemata, and cultural knowledge may be among the main factors influencing successful reading comprehension. This seems to be especially true for EFL/ ESL reading.

      • SCOPUSSCIEKCI등재

        The Role of Aquaporin-4 in Cerebral Edema Formation after Focal Cerebral Ischemia in Rats

        Song, Young-Jin,Bae, Hae-Rahn,Ha, Se-Un,Huh, Jae-Taeck The Korean Neurosurgical Society 2007 Journal of Korean neurosurgical society Vol.41 No.1

        Objective : To elucidate the role of aquaporin-4[AQP4] in cerebral edema formation, we studied the expression and subcellular localization of AQP4 in astrocytes after focal cerebral ischemia. Methods : Cerebral ischemia were induced by permanent middle cerebral artery[MCA] occlusion in rats and estimated by the discoloration after triphenyltetrazolium chloride[TTC] immersion. Change of AQP4 expression were evaluated using western blot. Localization of AQP4 was assessed by confocal microscopy and its interaction with ${\alpha}-syntrophin$ was analyzed by immunoprecipitation. Results : After right MCA occlusion, the size of infarct and number of apoptotic cells increased with time. The ratio of GluR1/GluR2 expression also increased during ischemia. The polarized localization of AQP4 in the endfeet of astrocytes contacting with ventricles, vessels and pia mater was changed into the diffuse distribution in cytoplasm. The interactions of AQP4 and Kir with ${\alpha}-syntrophin$, an adaptor of dystrophin complex, were disrupted by cerebral ischemia. Conclusion : The deranged spatial buffering function of astrocytes due to mislocalized AQP4/Kir4.1 channel as well as increased assembly of $Ca^{2+}$ permeable AMPA receptors might contribute to the development of edema formation and the excitotoxic neuronal cell death during ischemia.

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