두 마리의 면역매개성 혈고판감소증 개에서의 MMF를 이용한 치료

손혜진,박형진,서경원,송근호 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

Two dogs (case 1: 4-years-old female Dachshund, case 2: 1-years-old male maltese) were reffered with petechia. Result of blood analysis and coagulation test reveled immune-mediated thrombocytopenia in all dogs. Treatment with MMF for them, case 1 present steroid-induced hepatopathy, case 2 present anemia, so treated with Human IgG and blood transfusion. 3(case 1) or 2(case 2) months after initial treatment, clinical features were improved, and continuous monitoring is needed.

Caffeine 과 Glucose 투여가 지구성 운동중 대사 및 호흡기능에 미치는 효과

박해근,전종귀,홍성표,민창기 忠南大學校體育科學硏究所 1986 體育科學硏究誌 Vol.4 No.1

Twelve male students (major in physical education; non-coffee drinkers; 6 endurance athletes; 6 non-athletes) were studied to determine the effects of caffeine, and Glucose feedings on submaximal endurance performance. Each subject performed three submaximal cycling trials at an absolute intensity of 900kpm. The trials were randomized to negate any possible order or training effects. For the caffeine trial, 2.5 mg/kg body weight of caffeine in 250ml of artificially sweetened barley tea was ingested twice one hour and 30.min prior to the ride. In the glucose trial, 0.5g/kg. body weight of glucose in 250m1 of barley tea was ingested twice one hour and 30 min prior to the ride. During the control trial, 250ml of artificially sweetened barley tea was ingested twice one hour and 30 min prior to the ride. obtained data from the three trials were analyzed with one way ANOVA for repeated measures design. Significant differences between means were located using a multivariate comparison. The level of significance was established at p<0. 05. The results were summerized as follows : Ingestion of glucose elevated blood glucose and insulin levels at rest , but no significant differences in blood glucose concentration were found between the three trials . Glucose ingestion resulted in rapid hypoglycemia and inhibition of FFA mobilization during exercise. Caffeine ingestion increased significantly in VE, Vo2 and plasma osmolarity during the exercise. But caffeine ingestion failed to elevate plasma FFA concentration, HR and blood pressure significantly. Glucose or caffeine ingestion did not change in blood lactate, Hb , plasma Na+ concentration, Hit and RQ during exercise. In the above results, It was suggested that ingestion of caffeine prior to the exercise fail to increase in lipid metabolism during exorcise and may have some detrimental effects on endurance performance besides psychological ergogenic effect of caffeine, and that glucose ingestion prior to the exercise elevate blood glucose and insulin level at rest but may have detrimental effect of endurance performance because of rapid hypoglycemia caused by hyperinsulinemia.

고교 레슬링선수의 무산소성 파워 및 측정방법의 타당도에 관한 사례 연구

전해섭,윤재량,정동군,이희동,이정근 韓國體育大學校 1995 論文集 Vol.18 No.-

1) Anaerobic power by jump reach test record was not significant difference statistically between Free-style and Grecoroman-style player. 2) Anaerobic power by 50m Allout-running was not significant difference statistically between free-style player and Grecoroman-style player. 3) Anaerobic power by Lewis-nomogram After measure jump reach test record and weight was not significant difference statistically between Free-style player and Grecoroman-style player.. 4) Anaerobic maximal, Anaerobic mean power and total power were not significant difference statistically between Free-style and Grecoroman-style player. 5) Wingate test measurement method can substitution for Anaerobic power measurement method by Lewis-nomogram.

一部 農村住民의 傷病樣相에 關한 硏究

鄭海鍵,李性寬 慶北大學校 醫科大學 1981 慶北醫大誌 Vol.22 No.1

1980年 3月부터 1981年 2月까지 滿 1年間 慶北 軍戚郡의 3個部落 143個家口 男女 654名을 對象으로 傷病狀況의 前向性 調査成績을 要約하면 다음과 같다. 年間 傷病率은 男子 190%, 女子 240%로 女子에서 높았으며 年間 平均 罹病回數는 2.2回程度였고, 年齡別로는 4歲以下群에서 94.3%로 제일 높고 15~19歲群에서 제일 낮았다. 年間 急性疾患의 發生率은 78.9%이며, 件當 罹患率은 男子가 173.6% 女子가 212.8%로 女子에서 高率이었다(p<0.05). 敎育程度別 發生頻度는 未就學 兒童群이 87.3%로 제일 높고 다음이 無學群 83.6%로 次位이며 高卒群 66.7%로 제일 낮아, 대체로 學歷이 낮을수록 傷病發生頻度가 높은 경향이었다. 疾病別分布는 呼吸器系疾患이 71.3%로 제일 높고 다음이 神經系 및 消化器系疾患의 順이었다. 診斷名別로는 감기, 氣管支炎, 설사, 食中毒, 皮膚炎 및 外傷이었다. 慢性疾患의 有病率은 전체 15%로 女子가 16.9%로 男子 12.9%에 비해 높았고, 年齡이 增加할수록 有病率이 높은 것으로 나타났다. 敎育程度別로는 無學群이 제일 높았고, 高率群이 제일 낮아 敎育水準이 낮을수록 그 頻度가 높게 나타났다. 疾病別로는 神經系, 消化器系, 呼吸器系 및 循環器系疾患의 順으로 나타났다. 診斷名別로는 神經痛, 慢性胃腸炎, 胃潰瘍, 腦卒中, 瑞息 및 肺結核의 順으로 나타났다. 生活程度別 疾病 罹患率의 觀察에서 生活水準이 낮을수록 罹患率이 약간 높게 나타났으나 有意義한 差異는 없었다. 地域別 罹患率 調査에서 山嶽地域이 平野 및 中間地域에 比해 그 率이 높았다. 呼吸器系疾患의 경우 山嶽地域이 他地域에 比하여 현저히 높은 것을 제외하고, 傷病分類別 分布에 있어 크게 두드러진 樣相을 나타내지 않았다. 季節別 疾病 發生率 調査에서 春季가 54.1%로 제일 높고 夏季가 32.6%로 제일 낮았다. 呼吸器系疾患은 冬季에 제일 많이 發生했고 消化器系疾患은 春季에 가장 많았다. 疾病發生은 全國的인 流行에 따라 樣相에 影響을 미칠수 있으므로 정확한 疾病樣相을 把握하려면 長期間에 걸친 코호트 觀察이 要望되는 바이다. The present study was conducted to investigate the status of sickness through a prospective study for a year from March 1980 to February 1981. The subjects were 654 of 143 households of three villages, each one of mountainous, plain and intermediate area which were selected by cluster sampling in Gunee Gun, Kyungpook province. The results obtained are as follows : Annual spell morbidity rate was 22O percent 190 percent in male and 240 percent in female. The frequency of events per capita during a year among whole population was 1.9 in male and 2.4 in female. Age specific morbidity rate showed highest as 93.4 percrnt among 0-4 year group and lowest as 62.2 percent among 15-19 year group. Overall morbidity of acute diseases was 73.9 percent and spell morbidity rate was significantly higher in female (212.8%) than that in male (173.6%) (p<0.05). The morbidity rate was highest in pre-school age group (87.3%), followed in no schooling group (83.6%) and was lowest in high school group (66.7%). In general, the morbidity rate increased with decreasing educational level. The diseases of respiratory system were found the highest rate with 71.3 percent, and the diseases of the nervous system and sensory organs, and the diseases of the digestive system were followed. By kind of disease, common cold was highest and bronchitis, diarrhea, food poisoning, dermatitis and injuries were followed. The morbidity rate of chronic diseases was 15 percent and the rate was higher in female(19.9%) than that in male (12.9%). In general, the morbidity rate increased with aging and decreasing educational level. The diseases of the nervous system showed highest and the digestive system, the respiratory system, and the circulatory system were followed. By kind of disease, neuralgia showed highest, and chronic gastroenteritis, peptic ulcer, apoplexy and bronchial asthma were followed in order. There was no significant difference between morbidity rate and living level. The spell morbidity rate was highest at 283.1 percent in mountainous area. The next was 172 percent in plain area. The morbidity rate of the respiratory diseases revealed much higher in mountainous area compared to others. In spring the morbidity rate showed the highest rate with 54.1 percent among both male and female population, and in summer, lowest. The diseases of the respiratory system and the diseases of the digestive system were frequently prevailed in winter and in spring, respectively.

Takayama 방법에 의한 항내 파고 분포 계산

이해종,편종근 명지대학교 공학기술연구소 1989 공학기술연구소 논문집 Vol.4 No.-

In designing a new harbor or expanding and modifying the port facilities, one of the great concerns is how to reduce the disturbance of water inside a harbor. The calmness may be influenced by many external factors such as waves, winds, and currents, in which waves are the most influential. Waves are composed of incident wave, reflected wave, transmitted wave, ship wave, wind generating wave and long period oscillations. Among them, incident wave and reflected wave are most important to estimate the wave height distributions around a harbor. In this paper, wave height distributions in HUPO harbor is calculated with numerical model, which are Takayama's model, superposing Sommerfeld's solution. The validities of these model is also investigated by comparisons with experimental results. It is shown that the computational results of Takayama's model agree reasonably with the experimental values.

瓦松의 作用機轉에 關한 硏究

朴海根,金光鎭 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.1

Orostachys malacophyllus Fischer is a plant to grow on the tiled roof of the old house, and on the rock in the mountain. And the chemical compositions of the plant have not known yet. But it has transmitted to this day as a kind of medical plant from remote antiquity. Sometimes, it is used in the folk remedies for the treatment of the malignant diseases. This study was attempted to investigate the effects of water extract or water fraction on the Na-K-ATPase activity, on the renal functions, and on the contractility of the cardiac and intestinal muscles. The results obtained were summarized as follows: 1. The activity of Na-K-ATPase purified from the outer medulla of pig was increased at 0. 01%, and was decreased at 0.1% of the water extract. 2. In the study of the renal functions of rabbits, urine volume, glomerular filtration rate (GFR), and renal plasmaflow (RPF) were decreased by water extract, and their decreased phenomena were continued after infusion of physiological saline 3. The free water clearance of rabbit kidneys was decreased significantly by water extract. 4. The contractilities of the isolated ventricular muscles of turtles were increased, and of muscle strips of mice intestine were decreased by the addition of water extract. 5. The contractilities of the isolated ventricular muscles of turtles were decreased, and of the muscle strips of mice intestine were increased by the addition of water fraction from alcohol extract. 6. The increased contractility of the cardiac or intestinal muscle was inhibited significantly by the addition of the mixed solution with verapamil.

Bonded SOI 웨이퍼 제조를 위한 기초연구

정해도,문도민,강성건,류근걸 釜山大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.52 No.-

SOI(Silicon On Insulator)기술은 MOS(Metal-Oxide Semiconductor), CMOS(Complementary MOS)등의 전자집적회로 제조시 소자의 고속화, 고집적화, 저전력화, 발열 특성의 향상 등의 효과를 기대할 수 있다. 간략하게 Bonded SOI웨이퍼의 제조를 설명하면 SiO₂를 성장시킨 웨이퍼와 경면 가공한 다른 웨이퍼를 접합하여 열처리 등 후공정을 행한 후 한쪽 웨이퍼를 원하는 두께만큼 박막으로 가공한다. 본 연구에서는 기본적인 Bonded SOI 웨이퍼의 제조 공정 기술을 획득하고, 이를 통해 두께 3㎛ 이하, 표면거칠기 5Å이하의 상부 실리콘 박막을 가공하였다. SOI(Silicon On Insulator) technology is many advantages in the fabrication of MOS(Metal-Oxide Semiconductor) and CMOS(Complementary MOS) structures. These include high speed, lower dynamic power consumption, greater packing density, increased radiation tolearence et al. In the smiplest form of bonded SOI wafer manufacturing, creating, a bonded SOI structure involves oxidizing at least one of the mirror polished silicon surfaces, cleaning the oxidized surface and the surface of the layer to which it will be bonded, bringing the two cleanded surfaces together in close physical proximity, allowing the subsequent room temperature bonding to proceed to completion, and then following this room temperature joining with some form of heat treatment step, and device wafer is thinned to the target thickness. In this paper, The process of Bonded SOI wafer manufacturing is described briefly, and we made an attempt to manufacture the Bonded SOI safer that Si layer thickness is below 3㎛ and average roughness is below 5Å.

레슬링 自由型 競技 戰蹟에 關한 硏究 : (1904 Vienna to 1992 Barcelona) 歷代 올림픽 大會 中心으로

鄭東君,全海燮,李義東 韓國體育大學校 1994 論文集 Vol.17 No.-

From this research, the results of winning Olympic medals in free Style Wrestling have been analyzed, on the basis of the 1904 Vienna Olympics to the 1992 Barcelona. The medal results of all Weight Categories in the Olympic Participants are as follows: 1) The gold has been Crowned to USA in all Weight divisions, to URS Except Welter Weight, to JPN in Light Fly including 4 Categories, to TUR and KOR in 8 and 4 categories respectively. and the silver has also been given to USA in all categories, to URS in 9, TUR in 7, BUL, JPN, IRN, FIN, and SWE in 6 for each, and KOR in 3 Weight divisions. As for the bronze, USA and URS have won in all Weights, IRN and BUL in 7 for each, FIN and SWE in 6, and KOR, GBR and JPN in 5, and HUN in 4 categories. 2) The medals total gotten by each participant are that USA wins 41 golds including 32 silvers with 20 bronze, URS 31 golds with 17 silvers plus 15 bronzs, JPN 16 golds with 9 silvers plus 7 bronzes, FIN 8 golds with 7 silvers with 10 bronzes, SWE 8 golds including 10 silvers with 8 bronzes, BUL 6 golds with 15 Silvers Plus 9 bronzes, SUI 4 golds with 4 silvers plus 5 bronzes, GBR 4 golds including 4 silvers with 10 bronzes and KOR 4 golds with 4 silvers plus 6 bronzes. 3) The results of the competition can be reviewed by the spatial considerations such continents as Asia, Europe, and North and South America. The medals by the three are the same in the categories of Light Fly, Fly, Bantam and Feather. By conteast, the two continents of America, Europe outnumber Asia in the weights such as Light, Welter, Middleu and Light Heavy. It is interesting to mote that there is no gold in Asia in Heavy Weight divisions of Heavy and Super Heavy weight. Europe gets 86 golds including 89 silvers with 95 bronzes, America 42 golds with 36 silvers plus 26 bronzes and Asia 25 golds including 28 silvers with 32 bronzes in Olympic. 4) As for the history of wrestling this match starts with 7 categories in Vienna Olympics, which is conducted with 10 weights from the 1972 Munhen Olympics through the slight category change expected to be modified in the future With considering dividing weights, some of them are not studied to be changed in such categories as in Feather, Light and Heavy weight. 5) As to the medals gotten by the KOR wrestlers, they win 14 medals in the Olympics of them, 4 golds are given to Mr. Jong-Mo Yang in 62kg, In-Tak Yu in 68kg, Jang-Soon Pa가 in 74kg, and Myung-Woo Han in 82kg, 4 silvers to Mr. Jung-Shin kim in 48kg, Chang-Sun chang and Jong-Kyu kim in 52kg and Jang-Soon Pa가 in 68kg and 6 bronzes to Mr Kap-Do Son in 48kg, Hae-Sub Jeon in 52kg, Eui-Kon Kim and Kyung-Sun Noh in 57kg, Jung-Keun Lee in 62kg, and Tae-Woo Kim in 90kg.

腸收縮機能에 미치는 Diazepm의 影響

林良洙,朴海根 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.2

This study was carried out to determine the effect of diazepam on the isolated intestinal smooth muscles. The intestinal mucle strips were prepared from mouse duodenum (about 2cm long) and were arranged isometrically, in vitro. Intestinal motility was recorded on a Physiograph (Four-A, Narco Biosystem) with force transducer (F-60) by means of Magnus method in Lock's solution. Diazepam significantly inhibited (p<0.001) the contractility of isolated smooth muscle in concentration of 0. 02, 0. 04, 0. 05, and 0.08mg/ml by dose dependently, and ceased the contraction in the concentration of 0.08mg/ml, and the effect of diazepam was not affected by presamina(10^-6M) propranolol (10^-4M), hexamethonium (10-5M), and acetylcholine (10-4b1). Diazepam inhibited the K^+-induced contraption by dose dependently and also in Ca^++-free Lock's solution, and effect of diazepam (0.08mg/ml) on muscle contraction was same pattern by the, effect of verapamil (10-7M). Diazepam (0.08mg/ml) decreased ^45Ca^++-uptake by the isolated intestinal muscle strip significantly (p<0.05) but more potent effect was observed by verapamil (10^-7M). These results suggested that diazepam inhibited the contractility by inhibiting the Ca++ movement by means of direct interaction with receptor in the muscle membrane.

개구리에서 산-염기 평형의 계절적 변동에 관한 연구

조석현,박해근 충남대학교 의과대학 지역사회의학연구소 1984 충남의대잡지 Vol.11 No.1

The influence of environmental temperature on the acid base balance of frog(Rana Temporaria Chosenica) blood was investigated at 25℃ all the year round. pH of blood was measured by means of Artrup method and Sigaard- Anderson's nomogram using pH meter(Corning) and tonometer. Buffer value, actual bicarbonate concentration and OH^-/H^+ ratio were calculatedd by the measure buffer line, pH and CO2 gas tension which was used(low CO_2 was 4-5% and high C0_2 was 8-9% balanced with 0_2). Results obtained are as follows: 1. Buffer line was shift to the upper and-right side during winter season and the differences was statistically significant. 2. Buffer value was higher during winter season than summer value and the difference was significan (p<0.001). 3. The actual blood pH was 7.42±0.01 in September and 7.78±0.03 in January. Generally the pH was higher during winter season than that of summer. The difference between two seasons was statistically significant(p<0.05). 4. The blood PCO_2 value has a seasonal changes with low PC0_2 during winter season and the differences were statistically significant. 5. The plasma bicarbonate concentration was 17.00±1.07mM/L in September and the value were decreased with cold weather of 12.33±1.29mM/L in January. Seasonal changes were significantly different(p<0.05). It is concluded from this findings that the acid-base changes of blood in frog were related to the temperature of living habitat and the corresponding changes in the tissue energy store and buffers.