수면 유포 유류의 제거에 미치는 자성유체의 특성

신학기,신세건 한국환경과학회 2003 한국환경과학회지 Vol.12 No.1

Magnetite powder for kerosene-based ferrofluid was synthesize by air oxidation of waste acid containing Fe^2^+ and Fe^3^+ ions in the ph=11 at 60℃. stable kerosen-based ferrofluid was prepared by addition of polyoxyethylene nonyphencyl ether(POENPE) to the magnetite was examined by means of the fractionof solid dispersed FT-IR spectrum of an addition POENPE to the magnetite was examined by means of the fraction of solid dispersed FT-IR spectrum. And magnetic properties of kerosen-based ferrofluid were examined by method of Vibrating Sample Magnetometer. In order to oil on the water surface by an addition of kerosen-based ferrofluid, the optimum conditions were examined.

재발된 고혈압성 뇌실질내 출혈

배학근,정두신,도재원,이경석,윤일규 대한신경외과학회 1999 Journal of Korean neurosurgical society Vol.28 No.3

외상후 발작의 위험인자에 대한 조사

이재학,배학근,윤석만,도재원,이경석,윤일규,최순관,변박장 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

Risk Factors for Posttraumatic Seizure The authors evaluate the risk factors for posttraumatic seizures. this prospective study was performed in a series of 470 head injured patient from January 1996 to Decomber 1998. The patients who were dead within 1 week of injury or children from 3 years old and under were excluded. There were 358 male and 112 female with a mean age of 35.2±22.8 years (range, 4-88 years). The results were as follows : 1). Of the 470 patients, pasttraumatic seizure occurred in 48 patients(10.2%): early seizure in 28(6%) and late seizure in 20 patients(4.2%). 2). The clinical risk factors for posttraumatic seizure were poor consciousness at admission, presence of brainstem herniation signs, poor GCS score, and posttraumatic amnesia more than 24 hours after trauma(p<0.001). 3). The radiological risk factors for posttraumatic seizure were subdural hematoma(p<0.001), intracerebral hematoma (p<0.02), mutiple intracranial CT lesions(p<0.001), or delayed lesions on follow-up CT scans(p<0.001). the incidence of seizure increased according to the severity of diffuse brain lesion(p<0.001), and the seizure rate in mass lesion was higher than that in diffuse lesion(p<0.001). 5). Hypoxia and coagulopathy had a statistically significant influence on posttraumatic seizure(p<0.05). Hypoxia had a infuence on occurrence of late seizure(p<0.05). 6). The incidence of posttraumatic seizure signiticantly increased in surgical group compared with coservative group(p<0.001) and significantly increased in patient who underwent decompressive craniectomy compared with those who underwent craniotomy(p<0.001) 7). Preventive administration of antiepileptic drugs decreased the incidence of early seizure, but did not affect on the reduction of late seizure. 8). Multivariate logistic regression analysis showed the subdural hematoma, GCS score, delayed lesion, and intracerebral hematoma in order of importance for seizure risk. in conclusion, the risk factors affecting on the occurrence of seizure were clinical status at admission, CT lesions, and severity of diffuse brain inJury. Considering that hypoxia affected on the late seizure, it is necessary to detect and treat it immediately after trauma. In addition, the patients who underwent decompressive craniectomy should be carefully followed to evaluate the risk of late seizure. Even though preventive administration of antiepileptic drugs had a tendency to decrease the incidence of early seizure, it is unclear whether administration of antiepileptic drugs can reduce the incidence of posttraumatic seizures. Prospective study will be needed in the selected patients.

한국대학생의 음주양태와 생물정신사회적 요인의 상호관계

이창인,김학렬,박동건 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.5

연구목적 및 방법 : 본 연구는 한국 남자 대학생의 음주양태와 생물학적, 심리사회적 요소의 연관성을 알아보기 위해, 약4개월에 걸쳐 조선대학교 의과대학 의학과 학생 750명중 예비조사 결과 선정된 94명의 남학생을 대상으로 음주양태에 대한 설문지, 생활사건척도, 사회지지척도, 내-외 통제척도, 성격차원검사, 상태-특성 불안척도, 간이정신진단검사, 에탄올 삽포검사를 통해 다음의 결과를 얻었다. 결 과 : 1) 소량음주군과 과량음주군(이후 두 군으로 칭함)의 가족력 비교결과 소량음주군의 가족에서 음주후 급성 신체반응 민감자가 많았다(p〈.005). 2) 소량음주군에서 음주후 급성 신체반응이 많았으며(p〈.005). 과량음주군에서 음주후 심리적 유쾌감이 높았으며(p〈.005). 심리적 불쾌감은 차이가 없었다. 3) 성격, 심리, 환경적 특성비교에서 과량음주군이 성격차원검사의 외향성 척도가 높고(p〈.01). 사회 지지척도상 물질적 지지도가 높았다(p〈.01). 4) 에탄올 삽포검사상 15분, 30분, 60분후 모두 소량음주군의 양성반응율이 높았다(p 〈.005). 5) 한국형 알코올 사용척도(AUI) 하위요인을 비교한 결과 요인 1, 2, 4는 α=0.005 수준에서, 요인 3는 α=0.01 수준에서 과량음주군이 높았다. 6) 두 군의 음주양태 비교에서 소량음주군은 유사 비음주자. 숭화형 음주자가 많았고, 과량음주군은 일과성 사교음주자, 자제형 사교음주자, 습관적 과음자, 충동적 폭음자가 많았다(p〈.005). 두 군의 음주 양상의 차이는 과량음주군은 음주 의존도, 음주기간, 일일 음주성향, 음주선호, 술의 돗수, 막걸리, 소주 및 맥주의 평균 주량과 최대 주량, 맥주의 한 모금에 마시는 양은 α=0.01 수준에서 높으며, 소량음주자는 술을 마시는 두 모금사이의 시간이 유의하게 길었다(p〈.005). 7) 두 군의 사회인구학적 변인의 비교에서 과량음주군의 흡연율이 상대적으로 높았고(p〈.01), 가족들의 주거지를 보면 과량음주군은 대도시 출신이 많은 반면 소량음주군은 시골 출신이 많았으며(p〈.05), 동거 가족수는 소량음주군이 많은 편이었다(p〈.05). 그외의 다른 사회인구학적인 변인에서 과량음주군은 부모의 학력이 모두 높았고(p〈.05), 부모의 부부사이가 나쁜 편이었다(p〈.05). 결 론 : 알코올중독의 원인론과 그 특성에 대한 이해를 돕기 위해 비교적 균일하며 병적인 음주행태가 시작되는 대학생 집단에서 과량음주군과 소량음주군으로 나누어 비교했는데, 현저한 차이를 보이는 것은 ALDH 활성도 결핍과 강력히 연관된 것으로 추정되는 급성 신체(홍조)반응과 에탄올 삽포검사의 양성율의 차이였고 심리사회적인 측면은 다소의 차이가 있었으나 구체적인 해석에 어려움이 있었다. Objects and Methods : In order to evaluate the relationships between drinking habits and biological and psychosocial characteristics, the authors administrated the questionnaires about drinking patterns and acute physiological and psychological responses after drinking, several psychological scales and ethanol patch test to 94 male medical students in Chosun University. Results : 1) Low consumer group had significantly more severe physiological respondents after drinking in family members than high consumer group(p<0.05). 2) Low consumer group has significantly more severe acute physiological responses(p<0.005) and high consumer group revealed more positive psychological responses after drinking(p<0.05). But there was no difference in the degree of negative psychological responses between two group. 3) High consumer group had significantly more extroversion tendency(p<0.1) and received more financial support from family than low consumer group(p<0.1). 4) In the results of ethanol patch test, low consumer group showed more positive skin reaction in three test occasions than high consumer group (p<0.005). 5) Also the high consumer group revealed higher scores in factor 1, 2, 4(α=0.005), and 3(α=0.01) in comparison of factors of Korean Alcohol Use Inventory. 6) In comparison of drinking habits, low consumer group revealed higher incidence of nearly non-drinkers and sublimatory drinkers. But there were more casual social drinkers, sel-controlled social drinkers, impulsive-binge drinkers, and habitual-excessive drinkers in high consumer group(p<0.05). And in drinking patterns, the items of dependence and duration of drinking, daily drinking disposition, preferential beverage, average and maximum drinking amount of each liquor, and magnitude of sips taken were higher in high consumer group. Only one item of interval between sips was longer in low consumer group(o<.005). 7) In comparison of sociodemographic variables, there were more students who were smokers(p<0.1), from larger cities and small family(P<0.5), and whose parents were well educated(P<0.5) but had worse marital relationship(P<0.5) in high consumer group. Conclusion : For better explanation of the etiology and characteristics of alcoholism, we investigated the differences in various aspects between low alcohol consumers and high alcohol consumer in college students. The most evident differences lied in the degree of acute physiological reaction and positive rates of ethanol patch test that strongly suggested the relations with the activity of ALDH. Some differences in psychosocial aspects between two groups were noticed but could not appropriately be explained at this time.

60세 이상 환자의 척추수술

윤석만,이경석,도재원,배학근,윤일규 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

Objective: Advances in surgical technique, anesthesia and perioperative patient management, coupled with the rapid increase in the population of patients reaching their 60s or older, have led to a signiticant rise in spinal precedures. The objective of this study was to evaluate frequency of the disease, surgical results and postoperative complications of the aged patients who underwent spinal surgeries. Methods : We reviewed all spinal procedures for spinal lesions including degenerative diseases, trauma, tumor and others in patients aged 60 years or older between January 1 1994 and October 1 1998(56 men and 26 women), retrospectively. Final outcome was assessed by telephone interview with the patient or the family in 67.1%(55/82). Results : There were 56 male patients and 26 female patients. There were 57 cases of degenerative diseases, 14 cases of trauma, 5 cases of metastaisis, 4 cases of infection and 2 cases of others. According to the level of surgical procedures, there were 20 cases fo cervical spine, 8 cases of thoracic spine, 54 cases of lumbar spine. Postoperaive complications included the following(17/82): 7 dural tears, 2 sepsis, 2 nerve root injury and 6 others. There were no operation-related deaths. During follow up period, ten patients(12.2%) had died, 45 patients(54.9%) were contacted and 27 patients(32.9%) could not be located. Mean follow up period for the 45 patients contacted was 26.1±15.7 months. Of the 45 persons contacted, 34(75.6%) reported improvement, 6(13.3%) no change and 5(11.1%) aggravation of their preoperative symptoms. Conclusion: Spine surgery in patients aged 60 years or older has higher complication rate compare to the younger but it is reasonable to consider the surgical procedures even in the elderly if it is needed. We should give attention not to tear the dura during the surgical procedures, especially in the elderly.

자발성 뇌지주막하 출혈 환자에서 최초 뇌실 크기의 임상적 의의

신일영,윤일규,윤석만,도재원,이경석,배학근,최순관,변박장 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

The purpose of this study is to invesetigate the clinical significance of initial enlargement of ventricle in the patients who had aneurysmal SAH. Of the total 821 patients with aneursmal SAH who were registerd in SAH data bank system between 1989-1999, 307 patients who had been already measured in the size of ventricle at the time of admission, were studied retrospectively. The size of ventricle was calculated by bifrontal index. Normal size of ventricle was defined as 30% or less, mild enlargement was defined as 31 to 39%, and moderate enlargement of vertricle was defined as more than 39% in bifrontal index. The sizes of ventricle using bifrontal index were analysed according to the age, sex, blood pressure, consciousness at admission, medical history of hypertension, location of ruptured aneurysm, Fisher's grade on CT(computerized tomography) scan at the time of admission, cerebral vasospasm, intraventricular hemorrhage (IVH), performance of external ventricular drainage (EVD), and prognosis at discherge. Chi-square test and ANONA were used in the statistical evaluation. The results were as follows : 1) Of the 307 patients, 235(76.5%) had a mild to moderate enlargement of ventricle at the time of admission (more than 30% in bifrontal index). 2) The size of ventricle was enlarged according to the increase of age (p<0.05). 3) In the patients who had ruptured aneurysm on anterior cerebral artery, the size of ventricle significantly increased and showed a higher incidence in mild enlargement compared with moderate enlargement of ventricle (p<0.05). 4) The size of ventricle increased in th patients who had IVH and the EVD was more frequently performed in th patients who had the enlarged ventricle associated with IVH (p<0.05). 5) In the patients who had high Fisher's grade, the size of ventricle had a tendency to increase, but there was no statistical significance. 6) In the patients who had poor prognosis, the size of ventricle had a tendency to increase, but there was no statistical significance. Conclusively, the initial size of ventricle was enlarged in th aged patients, ruptured aneurysm on anterior communicating artery, high FIsher's grade, patients associated with IVH. Considering those factors, prediction for the enlargement of ventricle size may help to treat the patients suffering aneurysmal SAH.

Hypertensive Intracerebral Hemorrhage Associated with Unruptured Intracranial Saccular Aneurysms : Report of Three Cases 3례 보고

Bae, Hack Gun,Do, Jae Won,Lee, Keong Seok,Bae, Won Kyung,Yun, Il Gyu,Byun, Bark Jang 대한신경외과학회 1993 Journal of Korean neurosurgical society Vol.22 No.5

미파열 뇌동맥류를 동반한 고혈압성 뇌내출혈 3례를 보고한다. 3례 모두 초기병변은 피각부출혈로서, 전대뇌동맥의 형성부전이 있는 측으로 출혈이 있었다. 뇌동맥류는 뇌내출혈 반대측을 공급하는 뇌혈관을 따라 위치했다. 뇌동맥류 발생 원인이 혈행역학적 긴장(hemodynamic stress)으로서, 연령 및 고혈압과의 관계를 고려해 볼때, 고혈압성 뇌내출혈 환자에서 뇌동맥류 동반은 흔히 예상될 수 있는 병변이나, 아직 이에 대한 보고가 없다. 고혈압성 뇌내출혈 환자에서 미파열 뇌동맥류 동반에 대한 주의 및 이에 대한 추적조사가 요망된다.

Prepontine Chordoma without Bone Involvement : Case Report 증례보고

Bae, Hack Gun,Ohata, Kenji,Katsuyama, Junsuke,Hakuba, Akira 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.1

뇌교에 유착된 매우 드문 경막내 척색종 1례를 보고한다. 5년간의 추적기간 동안 광범위 종양절제에도 불구하고 두차례 재발했으며, 마지막으로 재발된 종양은 gamma knife로 치료되었다. 방사선 치료 1년후 검사한 핵자기공명 촬영상 뇌교부 종양은 감소된 반면, 천막열공 상부로 새로운 경막내 척색종이 보였다. 골밀도 뇌전산화단층 촬영상 두개골침범의 소견은 보이지 않았다. 두개골침범없는 경막내 척색종이 비교적 양성의 성격을띄운다 하더라도, 본증례의 재발양상은 뇌교와의 유착 및 종야의 뇌세포 침윤으로 인해, 두개골을 침범하는 고전적 척색종과 같은 aggressiveness를 보였다. 종양의 장기간 재발방지를 위한 보조적치료로 방사선치료가 요망된다. Presented here is an extremely rare case of intradural extraosseous chordoma with tenacious adhesion to the pons. During the 5 years' follow-up period, the tumor has recurred locally twice in the prepontine region despite radical excisions and final irradiation with gamma knife. Magnetic resonance image obtained 1 year after radiosurgery demonstrated a new intradural mass growing above the tentorial hiatus, whereas the mass within the pons was markedly reduced. High resolution computed tomographic scan showed no evidence of bone involvement. Even though intradural location without bone involvement is a relatively benign occurrence, the recurrent pattern suggests and aggressiveness that correlates classic chordoma because of its invasion to the pons. Adjuvant radiotherapy will be required in this case for a long-term control.

Primitive Neuroectodermal Tumor Arising from the Cerebellum : A Case Report 증례보고

Bae, Hack Gun,Lee, Kyeong Seok,Han, Dong Suk,Yun, Il Gyu,Lee, In Soo,Yang, Seung Ha 대한신경외과학회 1989 Journal of Korean neurosurgical society Vol.18 No.1

16개월된 소아에서 소뇌반구에 발생한 원시 신경외배엽성 종양 1례를 경험하여 문헌고찰과 함께 보고한다. 제거된 종양은 간충조직이 풍부하였고, 특이한 세포분화성을 보이지 않았다. We report a 16-month-old male with a primitive neuroectodermal tumor of the cerebellar hemisphere. This tumor consisted of undifferentiated cells resembling germinal or matrix cells of the embryonic neural tube and prominent mesenchymal component.

Outcome Following Diffuse Brain Injury in Children

Bae, Hack Gun,do, Jae Won,Lee, Kyeong Seok,Yun, Il Gyu,Lee, In Soo,Bae, Won Kyong 대한신경외과학회 1990 Journal of Korean neurosurgical society Vol.19 No.8-9

두부외상후 뇌전산화단층촬영상(CT) 종괴병변이 없는 소아환자 연속 100례를 대상으로 예후를 분석하였다. 대상 환자는 모두 15세 이하로 외상후 6시간이상 글라스고우 혼수계수가 8이하였다. 예후는 회복 27%, 중등도장애 17% , 중중장애 15%, 식물상태 2 % , 사망 39% 였다. 내원당시 글라스고우 혼수계수 5이하인 환자의 대부분은 사망하였다(81.9%). 내원당시 CT상 미만성뇌종창 소견은 53례에서 보였으며, 이중 27례(50.9%)에서 사망하였다. 예후에 나쁜 영향을 미치는 요인들로는 : 1) 내원당시 글라스고우혼수계수 5이하(p<0.05), 2) 저산소증(PaCO₂<60 ㎜Hg, p<0.05), 3) 뇌기저골절(p<0.005), 4) 폐 혹은 복부손상을 동반한 경우(p<0.005), 5) 미만성뇌종창(p<0.01), 6) 내원당시 CT상 뇌지주막하출혈, 뇌실내출혈 혹은 미량의 뇌경막하혈종이 있는 경우(p<0.05)였다. 연령, 성별, 두개골원개(skull vault) 골절, 두부를 제외한 다른 신체부위 골절 등은 예후에 영향을 미치지 못했다. 외상후간질이나 추적 CT상 나타난 지연성뇌병변은 불량한 예후를 나타내는 소견은 아니었다. 뇌량, 뇌기저핵부, 시상부, 혹은 상소뇌각 부위에 소량의 출혈 소견, 소위 말해 미만성뇌측색손상의 전형적인 CT 소견은 23례에서 나타났으나, 소아의 중증미만성뇌손상군에서는 불량한 예후를 반영하는 소견은 아니었다