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      • Non-volatile, Li-doped ion gel electrolytes for flexible WO<sub>3</sub>-based electrochromic devices

        Yun, Tae Yong,Li, Xinlin,Bae, Jaehyun,Kim, Se Hyun,Moon, Hong Chul Elsevier 2019 Materials & Design Vol.162 No.-

        <P><B>Abstract</B></P> <P>Flexible electrochromic devices (ECDs) based on Li-doped ion gels and tungsten trioxide (WO<SUB>3</SUB>) are demonstrated. Colored ECDs cannot be produced using conventional ion gels comprised of copolymers and room temperature ionic liquids (RTILs) due to a lack of cations that can be inserted into WO<SUB>3</SUB>. Based on considerations of the coloration mechanism, we developed Li-doped ion gels and applied these to devices. The effects of Li salt concentration are systematically examined, with respect to device dynamics, coloration efficiency, and transmittance contrast. In addition, the coloration/bleaching switching stability of the ECD produced using optimal Li salt content is investigated. The ECD exhibits distinct colored and bleached states even after 24 h operation in air. Using the described Li-doped ion gel electrolytes, flexible WO<SUB>3</SUB> ECDs were successfully demonstrated with good bending stability and no electrolyte leakage.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Non-volatile, Li-doped ion gel electrolytes are designed for flexible WO<SUB>3</SUB>-based ECDs. </LI> <LI> ECDs exhibit low voltage operation (–0.9 V) and large transmittance contrast (~85%) between colored and bleached states. </LI> <LI> Electrolyte leakage is not observed in flexible ECDs containing Li-doped gel electrolyte when bending deformation is applied. </LI> <LI> Flexible ECDs maintain ~90.3 and ~84.5% of initial optical transmittance and coloration efficiency after 1000 bending tests. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • Reversible dual-ion battery <i>via</i> mesoporous Cu<sub>2</sub>O cathode in SO<sub>2</sub>-in-salt non-flammable electrolyte

        Kwak, Kyung-Hwan,Suh, Hyun Jung,Kim, Ayoung,Park, Sanghyuk,Song, Juhye,Li, Siying,Kim, Youngkwon,Jeong, Goojin,Kim, Hansu,Kim, Young-Jun unknown 2019 Nano energy Vol.66 No.-

        <P><B>Abstract</B></P> <P>Finding a new battery chemistry is of urgent importance to reply diverse deployment trends of battery-driven devices. Here we propose a strategy to configure dual-ion storage battery based on SO<SUB>2</SUB> solvated chloroaluminate molten salt complex electrolyte employing Cu<SUB>2</SUB>O cathode material. The proposed battery chemistry is proven by two different couples of dual-ion (Li/Cl and Na/Cl) batteries that show about 590 Wh kg<SUP>−1</SUP> based on Cu<SUB>2</SUB>O mass with working voltage of 3.4 V as well as highly stable cycle performance up to 300 cycles. Further improvement may be possible by optimizing the electrode material with the compatible electrolyte composition, thus being another alternative to address various requirements of next-generation battery for future applications.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A dual ion battery system using Li (or Na) cations and Cl anions for the anode and cathode energy carriers. </LI> <LI> Self-formulated cathode material from a highly-safe and cost-effective Cu<SUB>2</SUB>O mesoporous nanosphere through in situ transformation to nanostructured CuCl as a Cl<SUP>-</SUP> anion storage material. </LI> <LI> Ensuring the safety of batteries using non-flammable and highly-conductive SO<SUB>2</SUB> based electrolyte. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>Highly-safe and cost-effective dual ion storage battery system are demonstrated by employing self-formulated CuCl cathode from mesoporous Cu<SUB>2</SUB>O nanosphere in conjunction with a non-flammable Li(or Na)AlCl<SUB>4</SUB>·xSO<SUB>2</SUB> inorganic liquid electrolyte.</P> <P>[DISPLAY OMISSION]</P>

      • KCI등재

        Lipolysis Effect of Daucosterol Isolated from Mulberry (Morus alba) Leaves

        Ke Li1(이커),Mi Lim Lee(이미림),Lu Que(루쿼),Mae Li(이매),Jum Soon Kang(강점순),Yung Hyun Choi(최영현),Kyung Mi Kim(김경미),Jae-Chul Jung(정재철),Dae Youn Hwang(황대연),Young Whan Choi(최영환) 한국생명과학회 2017 생명과학회지 Vol.27 No.12

        뽕나무는 약 40여 속과 1,000여 종이 있는 것으로 알려져 있으며, 항염증, 항진정, 지사작용, 노화억제 및 신경보호작용이 있는 것으로 알려져 있다. 본 연구에서는 아시아 지역에서 전통 한약재로 사용되는 뽕 나무 잎의 지방분해 활성에 관여하고 있는 물질을 스크린하기 위하여 뽕잎 분말을 헥산, 에틸 아세테이트 및 메탄올로 순차 추출하였다. 뽕 잎의 EtOAc 추출물로부터 daucosterol이 순수분리 되었으며, 그 구조는 1H, 13C, DEPT, COSY, HSQC 및 HMBC 등의 NMR스펙트럼 분석에 의해 밝혀졌다. Daucosterol은 농도 의존적으로 지질분해 효과를 나타내었는데, 본 연구의 결과로부터 뽕나무 잎으로부터 순수분리한 daucosterol의 지분분해 활성은 다양한 질병을 치료하기 위한 천연물 소재 또는 지표성분으로서 활용이 가능할 것으로 생각된다. 그러나 보다 효율적으로 이용하기 위해서는 daucosterol의 비만에 관한 생리활성 기작에 대한 추가적인 연구가 필요할 것이다. Plants are reservoirs of naturally occurring chemical compounds and of structurally diverse bioactive molecules. The aim of this investigation was to screen for the presence of phytochemicals responsible for the lipolysis activity in mulberry (Morus alba) leaves, which are important in traditional Asian medicinal plants. Powdered mulberry leaves were extracted with hexane, ethyl acetate, and methanol. Daucosterol was isolated from the EtOAc extract of mulberry leaves, and its structure was elucidated by NMR spectral analyses. The NMR assignments for the compound were determined using 1H, 13C, DEPT, COSY, HSQC, and HMBC NMR spectral data. Daucosterol showed a concentration-dependent lipolysis activity that may impart medicinal properties that can be exploited by medical practitioners for the treatment of various diseases. However, further studies should be conducted to elucidate additional mechanisms of daucosterol.

      • 한국형 공개SW 표준 플랫폼 BOOYO 기반의 WAS구축 및 SPECjAppServer2004 벤치마킹 연구

        김두현,김리라,정성인 건국대학교 산업기술연구원 2005 건국기술연구논문지 Vol.30 No.-

        We efficiently loaded Tomcat, JBoss, PostreSQL and Apache which are the core of publicly published open Source based WAS middleware on Booyo in Korea Open Source Standard Platform. This paper compare performance of Booyo with performance of foreign products using SPECjAppsserver2004 banchmark. In benchmark if Booyo increases a load, JOPS for a performance measurement unit falls a small number. Therefore. this paper describes a result and building a research WAS.

      • KCI등재

        Bortezomib과 Dexamthasone으로 치료한 골수외 형질세포종 4예

        백종현,이은영,장리라,손창배,신은경,서정아,이지숙,이호섭,이상민,신성훈,김양수 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

        Despite the use of aggressive local and systemic treatment including autologous stem cell transplantation in multiple myeloma, extramedullary recurrences are common and the prognosis of these patients is poor. Many novel drugs such as thalidomide, lenalidomide and bortezomib improve the response of treatment of multiple myeloma, but some reports failed to describe thalidomide has effect in extramedullary plasmacytoma. Recent data report on the successful treatment plasmacytomas with bortezomib in patients with advanced multiple myeloma. We treated 4 relapsed or refractory extramedullary plasmacytomas with bortezomib at our institution. We recognized all these extramedullary plasmacytomas decreased and showed more than partial response. This report lends support to the efficacy of bortezomib in the treatment of plasmacytoma and describes the safe use of bortezomib. Responses may, however, be of short duration. Therefore, despite our limited experience, we propose that bortezomib may be considered a therapeutic option for such patients who have risk of radiation therapy

      • 일부지역 청소년들의 건강행위 이행에 관한 조사연구 : 건강책임, 건강관심도, 건강행위, 건강통제위와의 관계 Relationship among Health Interest, Responsibility, Behavior and Health Locus of Control

        김현리 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2

        This study is purposed to discriminte the effect of health interest, health responsibility and health locus of control on the teenagers'health behavior. The. subject of this study was 409 boys and girls, high school 2nd grade students in G city. The period of data collection was from July 9. 1990 to July 14, 1990. Data analysis method is used SPSS-X program and frequency, number, mean, standard deviation, t value and Pearsons correlation coefficient were computed. The results of this study were as follows. 1. Hypothesis 1. "The higher health responsibility score is, the higher health behavior score is." is supported statistically (r=.2613, p<0.001). 2. Hypothesis 2. "The higher healh interest score is, the higher health behavior score is." is supported statisically (r=.1130, p<0.001) 3. Hypothesis 3. "The higher internal health locus of control tendency is, the higher health behavior score is." is statistically supported (r= 0.1013, p<0.001). 4. The health behavior score is positive correlation with internal locus of control (r=.1013. p<0.001) and external health locus of control (r=.2314 p<0.001). And there is no differnce between IHLOC group and EHLOC group in health behavior score(t= 0763, p<0.05). And so, I suggested that ; (1) We should find out the effect of health locus of control type on health behavior of single and multi dimension. (2) We should discriminate the dimension of health behavior. (3) We should search the nursing intervention method, such as reinforcement of health interest and health responsibility to develop health behavior.

      • 콘택트렌즈 보존 용기 유래 Acanthamoeba lugdunensis KA/L5주의 내공생세균

        정동일,공현희,김태호,황미열,유학선,윤호철,설성용 경북대학교 의학연구소 1999 경북대학교병원의학연구소논문집 Vol.3 No.1

        콘택트렌즈 보존 용기 유래 가시아메바 KA/L5주의 세포질 내에 존재하는 bacterial endosymbiont(내공생세균)를 투과전자현미경으로 관찰하여 확인하였다. 숙주인 가시아메바 KA/L5주는 형태학적으로 제2군에 속하였고, rDNA PCR-RFLP 결과 A. lugdunensis로 동정되었다. 미토콘드리아 DNA RFLP와 동위효소 분석상 이 충주는 국내 콘택트렌즈 보존용기에서 가장흔히 분리되는 type인 KA/Ll주, 국내 임상 분리주 중 하나인 KA/E2주, 내공생세균을 가지는 것으로 보고된 병원 냉각수 유래 KA/W4주 및 L3a주와 동일하거나 매우 유사한 성적을 보였다. 내공생세균은 약 1.38× 0.507㎛의 크기였고, 아메바 세포질 내에 불규칙하게 분포하고 있었으며. 그 표면에 아메바의 ribosome이 부착되어 있었다. 내공생세균을 둘러싼 lacunae나 막과 같은 구조는 관찰되지 않았다. Legionella 특이 primer를 이용한 효소중합반응(PCR)에서 내공생세균의 염색체 DNA는 증폭되지 않았다. A. lugdunensis의 우리말 이름을 담수가시아메바로 제안한다. Transmission electron microscopy of an Acanthamieba isolate (KA/L5) from a contact lens case revealed bacterial endosymbionts within cytoplasm of the amoebae, The Acanthamoeba isolate belonged to the morphological group II. Based on the polymerase chain reaction (PCR) - restriction fragment length Polymorphism (RFLP) of 18S ribosomal RNA coding DNA (rDNA), the Isolate was identified as A. lugdunensis. Strain typing by isoenzyme analysis using isoelectric focusing (IEF) and mitochondrial (Mt) DNA RFLP revealed that the isolate was closely related with KA/Ll , the most predominant type of isolates from contact lens storage cases, KA/E2, a clinical isolate, KA/W4, preciously reported to host endosymbionts, and L3a strains of A. lugdunensis. The endosymbionts were similar to those of KA/W4 In aspects that they were randomly distributed in both trophozoites and cysts, and were rod-shaped bacteria measuring approximately 1.38x 0.50㎛. But the number of endosymbionts per amoeba was significantly lower than that of KA/W4. They were neither limited by phagosomal membranes nor included In lacunae- like structure.

      • 일 종합병원 수간호사의 역할기대에 관한 연구

        김태숙,김현리 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2

        The purpose of this study was an attempt to examine the value of the nurses' and doctors' role expectation against that of the head nurses who are in charge of each ward. During the period from Nov. 5 to Nov. 10, 1990, data were collected from 119 nurses and 51 doctors who work in a hospital in Daejeon. Data analysis included percentage, mean, stadard deviation, t-test and ANOVA. The results were as follows: 1. The nurses total expectation score was higher than the doctors 218.82:185.82 (P<0.001). 2. In comparing each item: The nurses showed the highest score to the item about writing and sending all kinds of requests for work to the proper dept and confirming whether it completed or not (4.63). The item of educating once a week to ward staff got the lowest score (3.79). The doctors gave the highest score to the item concerning the implementation of nursing plans and sometimes doing things by herself (4.07). The item about explaining patient's conditions to the relatives got the lowest score (2.96). 3. In comparing by the factor: The nurses showed the highest expectation mean score for Operating Management (4.47) and the lowest one was for Education and Research (3.84). The doctors showed the highest expectation mean score for Direct Patient Care (3.90) and the 4. The score on the head nurse's role expectation were significantly higher in the satisfactory group than in the dissatisfactory group (P<0.01).

      • 임상간호사와 환자 및 보호자가 지각하는 환자역할

        소희영,김현리 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.2

        The general framework of references for this study consists of rights and responsibilities of the sick role by Parsons. The purpose of this study is to understand the perception about sick role of clinical nurse and patient & his guardian. The research tool was developed by investigation from the literature review. Subjects consisted of two non-random convenience sample, one was 148 clinical nurse; and the other was 199 patients and his gurdians. Data was collected by self administered questionaire from 1st June to 30th June 1987, at 2 general hospitals located in Daejeon. By SPSS, data were analyzed using mean, standard deviation, T-test, Pearson correlation. The results of the study may summarized as follows: 1. There was no difference between groups in actual level (P=.353) and discrepant score (P= .122), and statistically significant difference in expected level (P=.012), and importance (P= .004) 2. From the clinical nurse's view, actual level is correlated with expected level (r=.3855, P=000), importance (r=.2979, P=.000), and discrepant score (r=-.6958, P=.000). Expected level is correlated with importance (r=.8704, P=.000) and discrepant score (r=.3386, P=.000). Importance is correlated with discrepancy (r=.3150, P=.000). 3. From the patient and his guardian's view, actual level is correlated with expected level (r=.4289, P=.000), importance (r=.3812, P=.000), and discrepant score (r=-.8005, P=.000), Expected level is correlated with importance (r=.8833, P=.000). Therefore, nurses should make a great deal of efforts to improve the understanding of expected level and importance about sick role of patient and his guardian.

      • 재가노인의 일상생활동작수행의 의존성과 생활만족에 관한 연구

        홍춘실,김현리,이상화 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1

        This study was conducted to analyse the correlation between the ADL dependency and life satisfaction. Data were collected from the 102 home resident eldery who have no dementia by cognition test. The age distribution f subjects were 65 years and over The data were collected from January 16th to February 15th, 1997. The instruments used for this study were a survey of general characteristics(10 items), physical function(15 items), life satisfaction(20 items). The data were analysed by using an SPSS program and included percentage, t-test, ANOVA & Pearson correlation coefficient. The result of the study are summarized as follows: 1. The mean of ADL dependency score was 5..912 in a possible range of 15 to 60 when 15 indicates high dependency and 60 incicates low dependency. 2. The mean of life satisfaction score was 20.363 in a possible range of 0 to 40 when 0 indicates low life satisfaction and 50 indicates high life satisfaction. 3. The relationship between ADL dependency and life satisfaction for old people in home proved to be of statistically highly negative correlation(r=-.2553 P=.01). 5. General characteristics related to life satisfaction was educational status, household status, economic status, personality, perception of health(P<0.05). In conclusion, it was identified that ADL dependency is the important variable influencing the life satisfaction of the elderly. Therefore, more efforts are needed to decreased the ADL dependency of the elderly to enhance life satisfaction of the elderly.

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