Investigation of linear and nonlinear of behaviours of reinforced concrete cantilever retaining walls according to the earthquake loads considering soil-structures interactions

Gursoy, Senol,Durmus, Ahmet Techno-Press 2009 Structural Engineering and Mechanics, An Int'l Jou Vol.31 No.1

It is known that retaining walls were severely damaged as well in the most recent earthquakes having occurred in the countries in the active seismic belts of the world. This damage can be ascribed to the calculation methods used for the designs of retaining walls in the event of their constructions and employment having been accurately carried out. Generally simplified pseudo-static methods are used in the analysis of retaining walls with analytical methods and soil-structure interaction are not considered. In view of these circumstances, in this article by taking soil interaction into consideration, linear and nonlinear behaviours of retaining walls are analyzed with the assistance of LUSAS which is one of the structural analysis programs. This investigations are carried out per LUSAS which employs the finite element method as to the Erzincan (1992) Earthquake North-South component and the obtained findings are compared with the ones obtained from the method suggested in Eurocode-8, which is still effective today, and Mononobe-Okabe method. Not only do the obtained results indicate the distribution and magnitude of soil pressures are depend on the filling soil but on the foundation soil as well and nonlinear effects should be considered in designs of these walls.

Autoimmunity and intestinal colonization by Candida albicans in patients with type 1 diabetes at the time of the diagnosis

Gursoy, Semra,Kockar, Tuba,Atik, Sezen Ugan,Onal, Zerrin,Onal, Hasan,Adal, Erdal The Korean Pediatric Society 2018 Clinical and Experimental Pediatrics (CEP) Vol.61 No.7

Purpose: Type 1 diabetes mellitus (T1DM) is a chronic and immune-mediated disease, which is characterized by the progressive destruction of pancreatic beta cells. T1DM precipitates in genetically susceptible individuals through environmental factors. In this study, we aimed to evaluate the impact of autoimmunity and intestinal colonization of Candida albicans on the development of T1DM. Methods: Forty-two patients newly diagnosed with T1DM and 42 healthy subjects were included in this monocentric study. The basic and clinical characteristics of the patients were recorded. T1DM-, thyroid-, and celiac-associated antibodies were evaluated. Stool cultures for C. albicans were performed to assess whether or not gut integrity was impaired in patients with T1DM. Results: The evaluation of T1DM- and thyroid-associated antibodies showed that the prevalences of islet cell antibodies and antithyroperoxidase positivity were higher in the study patients than in the patients in the control group. Furthermore, the direct examination and culture of fresh stool samples revealed that 50% of the patients with T1DM and 23.8% of the control subjects had fungi (C. albicans). Conclusion: Through this study, we suggest that the presence of intestinal C. albicans colonization at the time of the diagnosis of T1DM may indicate impairment of normal intestinal microbiota. We also suggest that there may be a tendency of T1DM in patients with a high prevalence of intestinal C. albicans.

Investigation of the effects on earthquake behavior and rough construction costs of the slab type in reinforced concrete buildings

Gursoy, Senol,Uludag, Omer Techno-Press 2020 Advances in concrete construction Vol.10 No.4

In the architectural design process, the selection and configuration of the structural system significantly affect the earthquake behaviours of the reinforced concrete buildings. The main purpose of this study, the effects on the earthquake performances and the rough construction cost of the buildings of the slab type in reinforced concrete buildings are to examine comparatively for different local soil classes. The results obtained from this study have been determined that the building model having slabs with beams is safer compared to other types of slabs, especially when considering the vertical bearing structural elements (columns). It also shows that other types of slab, except for slab with beams, reduce the earthquake performances of reinforced concrete buildings, increase the displacement values, 1st natural vibration period values and the cost of rough construction. This matter reveals that slab type is quite important and the preference of beamed slabs in reinforced concrete buildings to be constructed in earthquake zones would be more appropriate in terms of safety and cost.

Determination of In Vitro Antioxidative and Antimicrobial Properties and Total Phenolic Contents of Ziziphora clinopodioides, Cyclotrichium niveum, and Mentha longifolia ssp. typhoides var. typhoides

Gursoy, Nevcihan,Sihoglu-Tepe, Arzuhan,Tepe, Bektas The Korean Society of Food Science and Nutrition 2009 Journal of medicinal food Vol.12 No.3

The aerial parts of Ziziphora clinopodioides, Cyclotrichium niveum, and Mentha longifolia ssp. typhoides var. typhoides were screened for their possible antioxidant and antimicrobial activities in addition to their penolic contents. Antioxidant activity was employed by two complementary test systems: 2,2'-diphenyl-1-picrylhydrazyl free radical scavenging and $\beta$-carotene/linoleic acid. In the first case, Z. clinopodioides was superior to the other species with a 50% inhibitory concentration value of $37.73\;{\pm}\;1.18\;{\mu}g/mg$. Similar results were obtained from the b-carotene/linoleic acid system. Inhibition capacity of the linoleic acid of Z. clinopodioides was $83.56\;{\pm}\;1.19%$. Additionally, antioxidant activities of butylated hydroxytoluene, curcumin, and ascorbic acid were determined in parallel experiments. Methanol extracts obtained from the plants studied were found to have moderate antimicrobial activity against all microorganisms tested. In general, Z. clinopodioides extract exhibited stronger activity than the other extracts. On the other hand, Acinetobacter lwoffii and Candida krusei were the most sensitive microorganisms for the all extracts. The amount of the total phenolics was highest in Z. clinopodioides extract ($129.55\;{\pm}\;2.26\;{\mu}g/mg$), followed by M. longifolia ssp. typhoides var. typhoides ($93.47\;{\pm}\;1.84\;{\mu}g/mg$). It is extremely important to note that there is a positive correlation between antioxidant activity potential and amount of phenolic compounds.

Determination of In Vitro Antioxidative and Antimicrobial Properties and Total Phenolic Contents of Ziziphora clinopodioides, Cyclotrichium niveum, and Mentha longifolia ssp. typhoides var. typhoides

Nevcihan Gursoy,Arzuhan Sihoglu-Tepe,Bektas Tepe 한국식품영양과학회 2009 Journal of medicinal food Vol.12 No.3

The aerial parts of Ziziphora clinopodioides, Cyclotrichium niveum, and Mentha longifolia ssp. typhoides var. typhoides were screened for their possible antioxidant and antimicrobial activities in addition to their penolic contents. Antioxidant activity was employed by two complementary test systems: 2,2′-diphenyl-1-picrylhydrazyl free radical scavenging and β-carotene/linoleic acid. In the first case, Z. clinopodioides was superior to the other species with a 50% inhibitory concentration value of 37.73±1.18μg/mg. Similar results were obtained from the β-carotene/linoleic acid system. Inhibition capacity of the linoleic acid of Z. clinopodioides was 83.56±1.19%. Additionally, antioxidant activities of butylated hydroxytoluene, curcumin, and ascorbic acid were determined in parallel experiments. Methanol extracts obtained from the plants studied were found to have moderate antimicrobial activity against all microorganisms tested. In general, Z. clinopodioides extract exhibited stronger activity than the other extracts. On the other hand, Acinetobacter lwoffii and Candida krusei were the most sensitive microorganisms for the all extracts. The amount of the total phenolics was highest in Z. clinopodioides extract (129.55±2.26μg/mg), followed by M. longifolia ssp. typhoides var. typhoides (93.47±1.84μg/mg). It is extremely important to note that there is a positive correlation between antioxidant activity potential and amount of phenolic compounds.

Evaluation of Antioxidant Activities of 3 Edible Mushrooms: Ramaria flava (Schaef.: Fr.) Quél., Rhizopogon roseolus (Corda) T.M. Fries., and Russula delica Fr.

Nevcihan Gursoy,Cengiz Sarikurkcu,M. Halil Solak,Bektas Tepe 한국식품과학회 2010 Food Science and Biotechnology Vol.19 No.3

The methanolic extracts of Ramaria flava,Rhizopogon roseolus, and Russula delica were analyzed for their antioxidant activities in different test systems including β-carotene/linoleic acid, 1.1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging, reducing power, and metal chelating activities in addition to their total phenolic and flavonoid contents. In the first case,methanol extract of R. roseolus showed the strongest activity. In DPPH system, the scavenging effects increased with the concentration. The reducing power of the mushroom also increased with concentration. Chelating effect was 96.75±0.28% for R. flava. In the case of total phenolic and flavonoid assays, R. flava found to have the highest phenolic content. Total flavonoid content of R. flava again found the superior to the other mushrooms. Experimental results indicate that the mushroom species evaluated here can be consumed safely. On the other hand, knowing the biological activity of these mushrooms will contribute to the establishment of conscious consumption.

Ineffective Doses of Dexmedetomidine Potentiates the Antinociception Induced by Morphine and Fentanyl in Acute Pain Model

Unal, Mumin,Gursoy, Sinan,Altun, Ahmet,Duger, Cevdet,Kol, Iclal Ozdemir,Kaygusuz, Kenan,Bagcivan, Ihsan,Mimaroglu, Caner The Korean Society of Pharmacology 2013 The Korean Journal of Physiology & Pharmacology Vol.17 No.5

The aim of this study was to evaluate the synergistic potentiation effect of ineffective doses of dexmedetomidine on antinociception induced by morphine and fentanyl in acute pain model in rats. Seventy albino Wistar rats were separated into 7 groups. Data for the control and sham groups were recorded. The ineffective dose of dexmedetomidine was investigated and found to be 3 ${\mu}g/kg$. Each group was administered the following medications: 3 mg/kg morphine (intraperitoneal) to Group 3, 5 ${\mu}g/kg$ fentanyl (intraperitoneal) to Group 4, dexmedetomidine 3 ${\mu}g/kg$ (subcutaneously) to Group 5, dexmedetomidine 3 ${\mu}g/kg$ (subcutaneous)+3 mg/kg morphine (intraperitoneal) to Group 6 and finally 3 ${\mu}g/kg$ dexmedetomidine (subcutaneous)+5 ${\mu}g/kg$ fentanyl (intraperitoneal) to Group 7. Just before the application and 15, 30, 60, 90 and 120 min after the administration of medication, two measurements of tail flick (TF) and hot plate (HP) tests were performed. The averages of the measurements were recorded. TF and HP latencies were the main outcomes. The analgesic effect of the combinations with dexmedetomidine+morphine (Group 6) and dexmedetomidine+fentanyl (Group 7), compared to the analgesic effect of morphine alone and fentanyl alone was significantly higher at 15, 30, 60 and 90 minutes after administration. In this study, dexmedetomidine in ineffective doses, when combined with morphine and fentanyl, potentiates the effects of both morphine and fentanyl.

ON GENERALIZATIONS OF SKEW QUASI-CYCLIC CODES

Bedir, Sumeyra,Gursoy, Fatmanur,Siap, Irfan Korean Mathematical Society 2020 대한수학회보 Vol.57 No.2

In the last two decades, codes over noncommutative rings have been one of the main trends in coding theory. Due to the fact that noncommutativity brings many challenging problems in its nature, still there are many open problems to be addressed. In 2015, generator polynomial matrices and parity-check polynomial matrices of generalized quasi-cyclic (GQC) codes were investigated by Matsui. We extended these results to the noncommutative case. Exploring the dual structures of skew constacyclic codes, we present a direct way of obtaining parity-check polynomials of skew multi-twisted codes in terms of their generators. Further, we lay out the algebraic structures of skew multipolycyclic codes and their duals and we give some examples to illustrate the theorems.

Processing of in-situ SiC reinforced AlN based composites

Ayse Kalemtas,Gursoy Arslan,Pinar Kaya,Servet Turan,Ferhat Kara 한양대학교 세라믹연구소 2018 Journal of Ceramic Processing Research Vol.19 No.2

In this study, highly dense (>97%) in-situ SiC reinforced AlN based ceramic-metal composites were produced by pressurelessreactive infiltration of 7075 aluminium alloys into porous α-Si3N4, α-Si3N4 + 4 wt. % carbon and α-Si3N4 + 8 wt. % carbonpreforms at 1400 oC for 4 hours under an argon gas atmosphere. X-ray diffraction and transmission electron microscopyanalysis of the designed α-Si3N4-Al and α-Si3N4-C-Al composites revealed that Si3N4 was completely consumed during theinfiltration process via reacting with the Al alloy and resulted in the formation of AlN and Si phases. The aim of the currentwork was to introduce a novel method to produce in-situ SiC reinforced AlN based ceramic-metal composites. Composites withrelatively low metal contents were successfully fabricated through incorporating active carbon to the starting α-Si3N4 powder,which in turn consumes the liberated metallic Si phase in the system via chemical reactions leading to the formation of SiCceramic phase. Formation of in-situ SiC, AlN and metallic Si were also confirmed by analytical transmission electronmicroscopy investigations.

Phenytoin-induced gingival overgrowth in un-cooperated epilepsy patients

Ismail Marakoglu,Ulvi Kahraman Gursoy,Hulya Cakmak,Kamile Marakoglu 연세대학교의과대학 2004 Yonsei medical journal Vol.45 No.2

Phenytoin-induced gingival overgrowth is a well-known and frequently reported gingival lesion, which was first detected in 1939. However, there are conflicts in the literature about the agents which affect the severity of the lesion. Un-cooperative dental patients are one of the most unsuccessfully treated periodontal patient groups because of the difficulty in maintaining their oral hygiene. This case report consists of two cases with the same characteristics: phenytoin usage, comprehension and speech defects and poor oral hygiene, but each case differs in the duration of the phenytoin therapy. Both of the cases received scaling, root planning and a gingivectomy.