Increased Serum Brain-derived Neurotrophic Factor, Nerve Growth Factor, Glial-derived Neurotrophic Factor and Galanin Levels in Children with Attention Deficit Hyperactivity Disorder, and the Effect of 10 Weeks Methylphenidate Treatment

Cavithan Gumus(Cavithan Gumus ),Ipek Percinel Yazici(Ipek Percinel Yazici ),Kemal Utku Yazici(Kemal Utku Yazici ),Bilal Ustundag(Bilal Ustundag ) 대한정신약물학회 2022 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.20 No.4

Objective: This study aimed to investigate the levels of serum brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), glial cell-derived neurotrophic factor (GDNF) and galanin in children with attention deficit hyperactivity disorder (ADHD). Methods: The study included 58 cases with ADHD and 60 healthy controls. Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version (K-SADS-PL) together with Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5) criteria were used for diagnostic evaluation. Sociodemographic data form and Conners’ Parent/Teacher Rating Scale-Revised:Long Form were applied to all cases. The serum levels of BDNF, NGF, GDNF, and galanin were evaluated in all subjects. Afterwards, methylphenidate was started in the ADHD group. ADHD cases were reevaluated in terms of the serum levels of BDNF, NGF, GDNF, galanin at the 10th week of treatment. Results: Before the treatment, the levels of BDNF, NGF, GDNF, galanin were significantly higher in the ADHD group compared to the control group. The levels of BDNF, NGF, GDNF, galanin were found to be significantly lower after treatment in ADHD group compared to pre-treatment. No correlation was between scale scores and the serum levels of BDNF, NGF, GDNF, galanin. Conclusion: The levels of neurotrophic factors and galanin were thought to be parameters worth evaluating in ADHD. Further studies on the subject with longer-term treatments and larger sample groups are required.

Dynamical Behavior of a Third-Order Difference Equation with Arbitrary Powers

Gumus, Mehmet,Abo-Zeid, Raafat,Ocalan, Ozkan Department of Mathematics 2017 Kyungpook mathematical journal Vol.57 No.2

The aim of this paper is to investigate the dynamical behavior of the difference equation $$x_{n+1}={\frac{{\alpha}x_n}{{\beta}+{\gamma}x^p_{n-1}x^q_{n-2}}},\;n=0,1,{\ldots}$$, where the parameters ${\alpha}$, ${\beta}$, ${\gamma}$, p, q are non-negative numbers and the initial values $x_{-2}$, $x_{-1}$, $x_0$ are positive numbers. Also, some numerical examples are given to verify our theoretical results.

Analysis of Induction Motor-pump System Supplied by a Photovoltaic Generator for Agricultural Irrigation in Southeastern Anatolian Region of Turkey

Gumus, Bilal,Yakut, Yurdagul Bentesen The Korean Institute of Electrical Engineers 2015 Journal of Electrical Engineering & Technology Vol.10 No.3

In agricultural systems, significant amount of energy is consumed during irrigation periods. Therefore operating irrigation systems with electrical energy produced by solar energy is very important. It is be possible to operate irrigation systems which have small-pump power like drip-irrigation with electrical energy produced by solar energy. Electrical energy produced by photovoltaic panels can vary from the estimated value due to environmental factors. Consequently analysis of a real system's performance is important. Thus, more correct projections can be made for the systems which will be designed. In this study, induction motor-pump mechanism for drip-irrigation system is operated with photovoltaic generator. Solar energy capacity of the established system is evaluated by measurements in irrigation periods. By means of simulations, power values produced by system and gained from the actual system are compared. Additionally the performance of induction motor is analyzed with the help of the driver system that increases the efficiency and controls the motor. As regards of results, design values of the drip-irrigation systems fed with solar energy in Southeastern Anatolian Regions of Turkey are obtained. Performance results of induction motor controlled with driver are also provided.

THE DYNAMICS OF POSITIVE SOLUTIONS OF A HIGHER ORDER FRACTIONAL DIFFERENCE EQUATION WITH ARBITRARY POWERS

GUMUS, MEHMET,SOYKAN, YUKSEL The Korean Society for Computational and Applied M 2017 Journal of applied mathematics & informatics Vol.35 No.3

The purpose of this paper is to investigate the local asymptotic stability of equilibria, the periodic nature of solutions, the existence of unbounded solutions and the global behavior of solutions of the fractional difference equation $$x_{n+1}=\frac{^{{\alpha}x}n-1(k+1)}{{\beta}+{\gamma}x^p_{n-k}x^q_{n-(k+2)}}$$, $$n=0,1,{\dots}$$ where the parameters ${\alpha}$, ${\beta}$, ${\gamma}$, p, q are non-negative numbers and the initial values $x_{-(k+2)}$,$x_{-(k+1)}$, ${\dots}$, $x_{-1}$, $x_0{\in}\mathb{R}^+$.

Fatty Acid Composition of Fry Mirror Carp (Cyprinus carpio) Fed Graded Levels of Sand Smelt (Atherina boyeri) Meal

Gumus, Erkan Asian Australasian Association of Animal Productio 2011 Animal Bioscience Vol.24 No.2

The effect of replacement of fish meal (FM) in diets with sand smelt meal (SSM) on fatty acid composition of carp fry, Cyprinus carpio, was examined. Five isonitrogenous and isoenergetic (38% crude protein, $15.75\;kJ\;g^{-1}$) diets replacing 0, 25, 50, 75, and 100% FM protein by SSM protein were formulated. Each diet was randomly allocated to triplicate groups of fish in aquaria, and each aquarium was stocked with 20 fish (initial average weight of $0.300{\pm}0.65\;g\;fish^{-1}$). Fish were fed twice daily to apparent satiation for 13 weeks. Results indicated that final weight, specific growth rate and feed efficiency ratio of fish fed with different SSM replacement diets did not differ significantly (p>0.05) from fish fed the control diet, except for 100% SSM level. No significant differences were noted among experimental treatments on dry matter, protein, lipid and ash contents of the fish body composition (p>0.05). Fatty acid analysis showed that saturated fatty acids in fish muscle significantly decreased, but monounsaturated fatty acids (MUFA) and polyunsaturated fatty acids (PUFA) did not change with increasing dietary SSM. However, some changes also could be observed for some particular fatty acids in experimental fish. For example, the amounts of 15:0, 17:0, 18:1n-7, 18:2n-6 and 22:5n-3 significantly increased, but 16:0, 18:1n-9, 18:3n-3 and 20:1 n-9 significantly decreased with increasing dietary SSM. Total n-6 PUFA increased with increasing dietary SSM, but total n-3 PUFA were not changed in muscle of fish fed the experimental diets. The ratio of n-3 to n-6 was not affected significantly in muscle of fish fed the experimental diets containing different proportions of SSM, including the control diet.

TG Index, its Graphical Matrix Representation and Application on Polyenes

Gumus, Selcuk,Turker, Lemi Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.5

A novel topological index (TG Index) has been introduced. The graphical matrix representation of the TG index includes the use of directed subgraphs for the first time in graph theory literature. The application of the TG index on certain properties of polyenes yielded very well correlation data.

Computerized analysis of occlusal contacts in bruxism patients treated with occlusal splint therapy

Gumus, Hasan Onder,Kilinc, Halil Ibrahim,Tuna, Suleyman Hakan,Ozcan, Nihal The Korean Academy of Prosthodonitics 2013 The Journal of Advanced Prosthodontics Vol.5 No.3

PURPOSE. Occlusal splints are commonly used to prevent tooth wear caused by bruxism. However, the effects of splints on occlusion are still unclear. Although it is rarely alluded in literature, splints can provoke severe occlusal alterations and other complications. This study was aimed to identify differences in the responses of individuals with bruxism and healthy individuals to a full-arch maxillary stabilization splint in terms of occlusal changes. MATERIALS AND METHODS. Occlusal contacts in 20 (5 male, 15 female) bruxism patients and 20 (5 male, 15 female) controls with normal occlusion were evaluated before and after occlusal splint therapy. T-Scan III, a computerized occlusal analysis system, was used to simultaneously measure occlusion and disclusion times as well as left-right and anterior-posterior contact distributions before splint therapy and 3 months after therapy. Wilcoxon and Mann-Whitney U tests were used for statistical analyses (${\alpha}$=.05). RESULTS. No differences were found in the posterior contact of bruxism patients before and after stabilization splint treatment. However, differences in posterior contact were observed between bruxists and normal individuals prior to treatment, and this difference disappeared following treatment. CONCLUSION. The results of this study showed the use of a stabilization splint may not have an effect on occlusion. However, the area of posterior occlusal contact among bruxists was found to be greater than that of normal individuals. According to this study, the clinical use of splints may be harmless.

Inhibition of Heat Resistant Molds: Aspergillus fumigatus and Paecilomyces variotii by Some Plant Essential Oils

Tuncay Gumus,Ahmet Sukru Demirci,Osman Sagdic,Muhammet Arici 한국식품과학회 2010 Food Science and Biotechnology Vol.19 No.5

In this study, the inhibitory properties of some essential oils including citrus (Citrus sinensis L. Osbeck),laurel (Laurus nobilis L.), myrtle (Myrtus communis L.),oregano (Origanum vulgare L.), and savory (Satureja thymbra L.) were investigated against the heat resistant molds Aspergillus fumigatus and Paecilomyces variotii isolated from margarine in a previous study in order to assess the potential for using these essential oils as a natural food preservative. In this study, the essential oils of the plants were obtained by steam distillation using Clevenger apparatus and were tested for antifungal activities at 0.25,0.50, and 1.00% concentrations. Inhibitory effects of the essential oils on the growth of the fungi followed the sequence: oregano=citrus>savory>laurel>myrtle. P. variotii was more resistant against the essential oils than A. fumigatus.

Xanthan Gum Production of Xanthomonas spp. Isolated from Different Plants

Tuncay Gumus,A. Sukru Demirci,Mustafa Mirik,Muhammet Arici,Yesim Aysan 한국식품과학회 2010 Food Science and Biotechnology Vol.19 No.1

Xanthan gum were produced from the following Xanthomonas strains; standard strain Xanthomonas campestris NRRL B-1459 and isolated strains Xanthomonas arbicola pv. juglandis, Xanthomonas axonopodis pv. vesicatoria, Xanthomonas axonopodis pv. begonia,Xanthomonas axonopodis pv. dieffenbachia. The viscosity features of the xanthan gums obtained were determined at 25-80℃ with different pH values and were compared to commercial xanthan gum. Our results indicate that X. arbicola pv. juglandis showed the highest productivity (8.22±1.52 g/L gum). This was followed by X. axonopodis pv. begonia (7.74±1.30 g/L gum), and the control bacterial strain X. campestris NRRL B-1459 (7.46±0.28 g/L gum). X. axonopodis pv. vesicatoria showed the lowest productivity (6.40±0.55 g/L gum). No xanthan gum could be obtained from X. axonopodis pv. dieffenbachia. Xanthan gum produced by X. axonopodis pv. vesicatoria showed the highest viscosity value (428 mPa·sec at 1%solution) in all Xanthomonas strains isolated from plants.

Analysis of Induction Motor-pump System Supplied by a Photovoltaic Generator for Agricultural Irrigation in Southeastern Anatolian Region of Turkey

Bilal Gumus,Yurdagul Bentesen Yakut 대한전기학회 2015 Journal of Electrical Engineering & Technology Vol.10 No.3

In agricultural systems, significant amount of energy is consumed during irrigation periods. Therefore operating irrigation systems with electrical energy produced by solar energy is very important. It is be possible to operate irrigation systems which have small-pump power like dripirrigation with electrical energy produced by solar energy. Electrical energy produced by photovoltaic panels can vary from the estimated value due to environmental factors. Consequently analysis of a real system’s performance is important. Thus, more correct projections can be made for the systems which will be designed. In this study, induction motor-pump mechanism for drip-irrigation system is operated with photovoltaic generator. Solar energy capacity of the established system is evaluated by measurements in irrigation periods. By means of simulations, power values produced by system and gained from the actual system are compared. Additionally the performance of induction motor is analyzed with the help of the driver system that increases the efficiency and controls the motor. As regards of results, design values of the drip-irrigation systems fed with solar energy in Southeastern Anatolian Regions of Turkey are obtained. Performance results of induction motor controlled with driver are also provided.