Pleural effusion due to intraoperative rupture of an infected renal cyst

Handan Gulec,Semih Degerli,Esra Ozayar,Fatma Bercin,Saziye Sahin 대한마취통증의학회 2012 Korean Journal of Anesthesiology Vol.62 No.5

Effect of Septoplasty on Voice Quality: A Prospective-Controlled Trial

Safak Gulec,Ismail Kulahli,Mehmet Ilhan Sahin,Kerem Kokoğlu,Murat Salih Gunes,Deniz Avci,Turan Arli 대한이비인후과학회 2016 Clinical and Experimental Otorhinolaryngology Vol.9 No.3

Objectives. The purpose is to investigate effect of septoplasty and widened nasal patency on voice quality. Methods. Fifty patients who undergone septoplasty were included in the study. Thirty-three people who had similar age and distribution were enrolled as control group. Before and 1 and 3 months after surgery, anterior rhinomanometry, voice analysis by Multi-Dimensional Voice Program, and spectrographic analysis were performed to patients. The recordings of /a/ vowel were used to evaluate average fundamental frequency (F0), jitter percent, and shimmer percent. In spectrographic analyses, F3–F4 values for the vowels /i, e, a, o, and u/, nasal formant frequencies of the consonants /m/ and /n/ in the word /mini/, and 4 formant frequencies (F1, F2, F3, and F4) for nasalized /i/ vowel following a nasal consonant /n/ in the word /mini/ were compared. The differences in nasal resonance were evaluated. All patients were asked whether change in their voices after the surgery. Preoperative and postoperative voice parameters and anterior rhinomanometry results were compared separately with the control group as well as in the patient group itself. Results. Preoperative total nasal resistance (TNR) values of patients were higher than the control group (P=0.001). TNR values of patients measured one day before surgery and after surgery in the 1st and 3rd months were different and these differences were significant statistically (P=0.001). There was no significant difference between the voice analysis parameters in preoperative, postoperative 1st, and 3rd months. As a result of their subjective reviews, 12 patients (36%) noted their voices were better than before surgery and 20 patients (61%) noted no change before and after surgery. Conclusion. Providing widened nasal cavity has no effect on voice quality.

Description of Pediatric Tuberculosis Evaluated in a Referral Center in Istanbul Turkey

Seda Geylani Gulec,Leyla Telhan,Tanyel Koçkaya,Ela Erdem,Banu Bayraktar,Ayse Palanduz 연세대학교의과대학 2012 Yonsei medical journal Vol.53 No.6

Purpose: Diagnosis of tuberculosis (TB) in children is more challenging than in adults. This study aimed to describe demographical, clinical and laboratory findings of children diagnosed with tuberculosis in Turkey, including the issues of contact tracing, culture positivity and forms of the disease. Materials and Methods: Clinical and laboratory data of 51 children with a mean age of 8.0±4.6 years who were diagnosed with TB were retrospectively reviewed. Main diagnostic tools included tuberculin skin test, chest X-ray, sputum/gastric aspirate culture with sensitivity testing,and direct microscopy for acid-fast bacilli on available samples. Clinical characteristics and outcomes of the patients were examined. Results: Thirty-six (70.6%) children were diagnosed with intra-thoracic and 15 (29.4%) with extra-thoracic tuberculosis. Twenty-eight of the patients had a positive Bacillus Calmette-Guérin vaccine scar (28/51, 54.9%) and 23/51 (45.1%) had a positive tuberculin skin test. An adult TB contact was identified in 27 (52.9%) of the cases. On direct microscopy, acid-fast bacilli were found in nine (17.6%) patients and positive culture for Mycobacterium tuberculosis was found in 19 (37.3%). Drug resistance to isoniazid was detected in four (7.8%). One patient with nephrotic syndrome and miliary tuberculosis died during follow-up. All other patients responded well to the treatment. Conclusion: Focusing on active contact tracing among all household contacts of tuberculous cases may be helpful in early identification and controlling childhood disease, even in regions with low disease prevalence. Adopting a suspicious and proactive approach in this particular age group is warranted.

A new paranormed series space using Euler totient means and some matrix transformations

G. Canan Hazar Gulec,Merve Ilkhan 강원경기수학회 2020 한국수학논문집 Vol.28 No.2

Paranormed spaces are important as a generalization of the normed spaces in terms of having more general properties. The aim of this study is to introduce a new paranormed space $ \left\vert \phi _{z}\right\vert \left( p\right) $ over the paranormed space $ \ell \left( p\right) $ using Euler totient means, where $p=\left( p_{k}\right) $ is a bounded sequence of positive real numbers. Besides this, we investigate topological properties and compute the $ \alpha -,\beta -,$ and $\gamma $ duals of this paranormed space. Finally, we characterize the classes of infinite matrices $(\left\vert \phi_{z}\right\vert \left( p\right) ,\lambda )$ and $(\lambda ,\left\vert \phi_{z}\right\vert \left( p\right) ),$\ where $\lambda $ is any given sequence space.

Effects of Golden Thistle (Scolymus hispanicus L.) on Cytotoxic Activity: Cell Cycle Arrest and Apoptotic Properties on the CaCo-2 Cell Line

Cansu Ozel-Tasci,Sukru Gulec 한국식품영양과학회 2022 Journal of medicinal food Vol.25 No.5

Cancer is a global concern for many individuals with high mortality rates, with colon cancer being the third most common diagnosed cancer worldwide. A phytochemical-rich diet is often recommended in the prevention and during the treatment of cancer cases. Golden thistle (GT) plant (Scolymus hispanicus L.) is a wild edible plant widely consumed in the Mediterranean countries. In this study, we aimed to obtain a hydromethanolic extract from three parts of the GT plant and test its antiproliferative activity in the CaCo-2 human adenocarcinoma cell line. Concentrations of the golden thistle extract (GTE) were used to treat CaCo-2 cells and the most significant reduction was detected with 4 mg/mL GTE after 72 h, with 78.3% decrease in cell viability (P < .05). Additionally, 4 mg/mL GTE caused 7.8-fold higher release of lactate dehydrogenase enzyme, indicating cell death after treatment. Flow cytometric analyses concluded both 3.3-fold higher early and late apoptotic activity of the 4 mg/mL GTE compared with the nontreated control group (P < .05). Last, 4 mg/mL GTE showed 24.1% reduction in the G1 phase and 38.1% increase in the S phase of cell cycle distribution. The alteration of G1 and S phases in the cell cycle led to growth reduction of CaCo-2 cells and caused apoptosis.

Increased Serum Level of P-Selectin in the Patients with Lichen Planus

Teoman Erdem,A.Ihsan Gulec,Akin Aktas,Abdulkadir Yildirim,Ahmet Kiziltunc 연세대학교의과대학 2004 Yonsei medical journal Vol.45 No.2

Lichen planus (LP) is a common, pruritic and inflammatory disease of the skin, hair follicles and mucous membranes. Immunologic mechanisms, especially cell-mediated immunity, play a major role in triggering the clinical expression of the disease. P-selectin is an adhesion molecule present within endothelial cells and mediates endothelial-leukocyte interactions. Therefore, it is considered that P-selectin plays an important role in LP. The aim of our study is to research the relation between P-selectin and LP. Serum P-selectin levels were determined with the enzyme- linked immunosorbent sandwich assay method in sera from 40 LP patients and 40 healthy controls. The serum levels of P-selectin were statistically significantly higher in the patients than in healthy controls (p<0.05), in female patients (39.32+/-11.34pg/ml) than in male patients (31.93+/-9.83 pg/ml) (p<0.01), and in the patients with eruptive form (40.27±9.32pg/ml) than in those with the localised (32.83±9.93 pg/ml) and hypertrophic (31.72±8.39pg/ml) forms (both p<0.01). In conclusion, we found a meaningful relation between LP and serum P-selectin levels.

Wilshire Grand: Outrigger Designs and Details for a Highly Seismic Site

Joseph, Leonard M.,Gulec, C. Kerem,Schwaiger, Justin M. Council on Tall Building and Urban Habitat Korea 2016 International journal of high-rise buildings Vol.5 No.1

The 1100 foot [335 m] tall Wilshire Grand Center tower under construction in Los Angeles illustrates many key outrigger issues. The tower has a long, narrow floor plan and slender central core. Outrigger braces at three groups of levels in the tower help provide for occupant comfort during windy conditions as well as safety during earthquakes. Because outrigger systems are outside the scope of prescriptive code provisions, Performance Based Design (PBD) using Nonlinear Response History Analysis (NRHA) demonstrated acceptability to the Los Angeles building department and its peer review panel. Buckling Restrained Brace (BRB) diagonals are used at all outrigger levels to provide stable cyclic nonlinear behavior and to limit forces generated at columns, connections and core walls. Each diagonal at the lowest set of outriggers includes four individual BRBs to provide exceptional capacities. The middle outriggers have an unusual 'X-braced Vierendeel' configuration to provide clear hotel corridors. The top outriggers are pre-loaded by jacks to address long-term differential shortening between the concrete core and concrete-filled steel perimeter box columns. The outrigger connection details are complex in order to handle large forces and deformations, but were developed with contractor input to enable practical construction.

Plasmapheresis in a Patient With "Refractory" Urticarial Vasculitis

Ozgur Kartal,Mustafa Gulec,Zafer Caliskaner,Oral Nevruz,Turker Cetin,Osman Sener 대한천식알레르기학회 2012 Allergy, Asthma & Immunology Research Vol.4 No.4

Immune complexes are found in the circulation of 30%-75% of patients with urticarial vasculitis and much evidence supports the role of these immune complexes in the pathogenesis of urticarial vasculitis. Plasmapheresis is effective for removing these immune complexes; however, there are few reports on the use of plasmapheresis in the treatment of urticarial vasculitis. We describe a case of “refractory” urticarial vasculitis in which the symptoms improved after plasmapheresis treatment. We suggest that plasmapheresis be considered as an option in patients with severe or treatment-resistant urticarial vasculitis.

Comparison of cone-beam computed tomography and panoramic radiography in the evaluation of maxillary sinus pathology related to maxillary posterior teeth: Do apical lesions increase the risk of maxillary sinus pathology?

Terlemez, Arslan,Tassoker, Melek,Kizilcakaya, Makbule,Gulec, Melike Korean Academy of Oral and Maxillofacial Radiology 2019 Imaging Science in Dentistry Vol.49 No.2

Purpose: The aims of this study were first, to compare panoramic radiography with cone-beam computed tomography (CBCT) for evaluating topographic relationships, such as the classification of maxillary posterior teeth and their distance to the maxillary sinus floor; and second, to determine the relationship between maxillary sinus pathology and the presence of apical lesions. Materials and Methods: In total, 285 paired CBCT and panoramic radiography records of patients (570 maxillary sinuses) were retrospectively analyzed. Both imaging modalities were used to determine the topographic relationship of the maxillary posterior teeth to the sinus floor. Mucosal thickening >2 mm was considered a pathological state. Data were analyzed using the chi-square, Wilcoxon, and Mann-Whitney U tests. Odds ratios (ORs) and confidence intervals(CIs) were calculated. Results: The closest vertical distance measurements made between posterior maxillary teeth roots and the maxillary sinus on panoramic radiography and CBCT scans showed statistically significant differences from each other(P<0.05). Compared to panoramic radiography, CBCT showed higher mean values for the distance between the maxillary sinus floor and maxillary posterior teeth roots. The CBCT images showed that at least 1 apical lesion adjacent to the right maxillary sinus increased the risk of maxillary sinus pathology by 2.37 times(OR, 2.37; 95% CI, 1.58-3.55, P<0.05). Conclusion: Panoramic radiography might lead to unreliable diagnoses when evaluating the distance between the sinus floor and posterior roots of the maxillary teeth. Periapical lesions anatomically associated with maxillary sinuses were a risk factor for sinus mucosal thickening.

CASE REPORT : Acute Urticaria Associated with Thyroid Papillary Carcinoma: A Case Report

Ozgur Kartal,Baysan Abdullah,Ersoy Ramazan,Gulec Mustafa,Calıskaner Zafer,Sener Osman 대한피부과학회 2012 Annals of Dermatology Vol.24 No.4