In-office dental bleaching with violet light emitting diode: bleaching efficacy and pulpal temperature rise

Guanaes Brunna Katyuscia de Almeida,Duarte Talyta Neves,Correr Gisele Maria,Kaizer Marina da Rosa,Gonzaga Carla Castiglia 대한치과보존학회 2022 Restorative Dentistry & Endodontics Vol.47 No.1

Objectives This study evaluated the bleaching efficacy of different in-office protocols associated with violet light emitting diode (V-LED), and measured the pulpal temperature rise caused by V-LED with or without gel application. Materials and Methods Bovine incisors were distributed in 4 groups (n = 10): VL – V-LED; HP – 35% hydrogen peroxide (control); HYB – hybrid protocol, V-LED applied without gel for 10 irradiation cycles followed by V-LED applied with gel for another 10 irradiation cycles; and HPVL – gel and V-LED applied for 20 irradiation cycles. Three bleaching sessions were performed with 7-day intervals. Bleaching efficacy was evaluated with ΔE * ab ΔEab* , ΔE00 and ΔWID. Data were recorded at baseline, 7, 14, 21 and 70 days. For pulpal temperature rise, thermocouples were placed inside the pulp chamber of human incisors. To determine intrapulpal temperature, the teeth were irradiated with V-LED with or without application of bleaching gel. Color difference data were analyzed by 2-way repeated measures ANOVA and Tukey’s test. Pulpal temperature was analyzed by t-test (α = 5%). Results VL exhibited lower color (ΔE * ab ΔEab* and ΔE00) and whiteness changes (ΔWID) than the other groups. HPVL presented higher color change values than HYB. HYB and HPVL showed not different ΔWID values; and HP showed the highest whiteness changes at all times. There were significant differences comparing ΔT with gel (8.9°C) and without gel application (7.2°C). Conclusions HPLV was more efficient than HYB. The 2 protocols with VL showed similar results to control. Gel application combined with VL promoted higher pulpal temperature than to the no gel group. Objectives This study evaluated the bleaching efficacy of different in-office protocols associated with violet light emitting diode (V-LED), and measured the pulpal temperature rise caused by V-LED with or without gel application. Materials and Methods Bovine incisors were distributed in 4 groups (n = 10): VL – V-LED; HP – 35% hydrogen peroxide (control); HYB – hybrid protocol, V-LED applied without gel for 10 irradiation cycles followed by V-LED applied with gel for another 10 irradiation cycles; and HPVL – gel and V-LED applied for 20 irradiation cycles. Three bleaching sessions were performed with 7-day intervals. Bleaching efficacy was evaluated with ΔE * ab ΔEab* , ΔE00 and ΔWID. Data were recorded at baseline, 7, 14, 21 and 70 days. For pulpal temperature rise, thermocouples were placed inside the pulp chamber of human incisors. To determine intrapulpal temperature, the teeth were irradiated with V-LED with or without application of bleaching gel. Color difference data were analyzed by 2-way repeated measures ANOVA and Tukey’s test. Pulpal temperature was analyzed by t-test (α = 5%). Results VL exhibited lower color (ΔE * ab ΔEab* and ΔE00) and whiteness changes (ΔWID) than the other groups. HPVL presented higher color change values than HYB. HYB and HPVL showed not different ΔWID values; and HP showed the highest whiteness changes at all times. There were significant differences comparing ΔT with gel (8.9°C) and without gel application (7.2°C). Conclusions HPLV was more efficient than HYB. The 2 protocols with VL showed similar results to control. Gel application combined with VL promoted higher pulpal temperature than to the no gel group.

Accessory mental foramen: A rare anatomical variation detected by cone-beam computed tomography

Marianna Guanaes Gomes Torres,Ludmila de Faro Valverde,Manuela Torres Andion Vidal,Ieda Margarida Crusoe-Rebello 대한영상치의학회 2015 Imaging Science in Dentistry Vol.45 No.1

The mental foramen is a bilateral opening in the vestibular portion of the mandible through which nerve endings, such as the mental nerve, emerge. In general, the mental foramen is located between the lower premolars. This region is a common area for the placement of dental implants. It is very important to identify anatomical variations in presurgical imaging exams since damage to neurovascular bundles may have a direct influence on treatment success. In the hemimandible, the mental foramen normally appears as a single structure, but there are some rare reports on the presence and number of anatomical variations; these variations may include accessory foramina. The present report describes the presence of accessory mental foramina in the right mandible, as detected by cone-beam computed tomography before dental implant placement.

Accessory mental foramen: A rare anatomical variation detected by cone-beam computed tomography

Torres, Marianna Guanaes Gomes,Valverde, Ludmila De Faro,Vidal, Manuela Torres Andion,Crusoe-Rebello, Ieda Margarida Korean Academy of Oral and Maxillofacial Radiology 2015 Imaging Science in Dentistry Vol.45 No.1

The mental foramen is a bilateral opening in the vestibular portion of the mandible through which nerve endings, such as the mental nerve, emerge. In general, the mental foramen is located between the lower premolars. This region is a common area for the placement of dental implants. It is very important to identify anatomical variations in presurgical imaging exams since damage to neurovascular bundles may have a direct influence on treatment success. In the hemimandible, the mental foramen normally appears as a single structure, but there are some rare reports on the presence and number of anatomical variations; these variations may include accessory foramina. The present report describes the presence of accessory mental foramina in the right mandible, as detected by cone-beam computed tomography before dental implant placement.

The Complex Surgical Management of the First Case of Severe Combined Immunodeficiency and Multiple Intestinal Atresias Surviving after the Fourth Year of Life

Guana, Riccardo,Garofano, Salvatore,Teruzzi, Elisabetta,Vinardi, Simona,Carbonaro, Giulia,Cerrina, Alessia,Morra, Isabella,Montin, Davide,Mussa, Alessandro,Schleef, Jurgen The Korean Society of Pediatric Gastroenterology 2014 Pediatric gastroenterology, hepatology & nutrition Vol.17 No.4

Severe combined immunodeficiency (SCID) is a life-threatening syndrome of recurrent infections and gastro-intestinal alterations due to severe compromise of T cells and B cells. Clinically, most patients present symptoms before the age of 3 months and without intervention SCID usually results in severe infections and death by the age of 2 years. Its association with intestinal anomalies as multiple intestinal atresias (MIA) is rare and worsens the prognosis, resulting lethal. We describe the case of a four year-old boy with SCID-MIA. He presented at birth with meconium peritonitis, multiple ileal atresias and underwent several intestinal resections. A targeted Sanger sequencing revealed a homozygous 4-bp deletion ($c.313{\Delta}TATC$; p.Y105fs) in tetratricopeptide repeat domain 7A (TTC7A). He experienced surgical procedures including resection and stricturoplasty. Despite parenteral nutrition-associated liver disease, the patient is surviving at the time of writing the report. Precocious immune system assessment, scrutiny of TTC7A mutations and prompt surgical procedures are crucial in the management.

Characterization of eight Bacillus thuringiensis isolates originated from fecal samples of Fuzhou Zoo and Fuzhou Panda Center

ChangbiaoWu,Lili Wu,Lingling Zhang,Ivan Gelbi,Lei Xu,Xiong Guana 한국응용곤충학회 2014 Journal of Asia-Pacific Entomology Vol.17 No.3

In eight fecal samples of 5 herbivorous animals from Fuzhou Zoo and Fuzhou Panda Center were found eightBacillus thuringiensis isolates. Obtained isolates were characterized by crystal microscopy, cry identification,and assay against the development of Eimeria tenella oocyst in chicken embryo. Bt WCB1, WCB2, WCB3 andWCB8, originated from horse, spotted deer, giant panda and lesser panda, respectively, all exhibited bipyramidaland cuboidal crystal and harbored the same cry genes, which were cry1Cb, cry1Db, cry1Fa, cry1Ib and cry2Ab. WCB7, a Bt isolate with bipyramidal crystal from zebra, showed a different cry pattern, cry1Cb, cry1Db, cry1Faand cry1Ia. BtWCB6, the third Bt isolate fromgiant panda, also contained bipyramidal crystal, however, harboredcry1Ib only. It was noted that Bt isolate WCB5 contained cuboidal crystal and harbored an unknown cry3 gene. It was very interesting that no cry genes were detected from Bt isolate WCB4 with dot-like crystal. Parasporalcrystal proteins of WCB3, WCB4 and WCB7 obviously inhibited the development of E. tenella oocyst in chickenembryo.

Secukinumab demonstrates superior efficacy and faster response in clearing skin of Asian patients compared to ustekinumab: a subgroup analysis of the CLEAR study

( Tsen Fang Tsai ),( Yu Huei Huang ),( Joo-heung Lee ),( Seung-chul Lee ),( Tae-gyun Kim ),( Derrick Chen Wee Aw ),( Weibin Bao ),( Michelle Dee ),( Adriana Guana ),( Min-geol Lee ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2

Background: Although secukinumab demonstrated superior efficacy to ustekinumab in patients with moderate-tosevere plaque psoriasis at 16 and 52 weeks in the global CLEAR study, subgroup analysis among Asian population has not been investigated so far. Objectives: We aimed to describe the efficacy and safety of secukinumab versus ustekinumab over 52 weeks in Asian patients with moderate-to-severe plaque psoriasis in the CLEAR study. Methods: Patients with moderate-to-severe psoriasis received either secukinumab 300mg or ustekinumab 45 or 90mg. Logistic regression analysis of PASI 75, PASI 90 and PASI 100 at week 16 and 52 using nonresponder imputation was conducted, P<0.05 was considered significant. Results: Sixty-two Asian patients were included in the subanalysis (23 secukinumab vs 39 ustekinumab). Secukinumab was superior to ustekinumab in achieving PASI 90 response at week 16. Superior efficacy was also observed for secukinumab vs ustekinumab with respect to PASI 75 and PASI 90 at week 52. Secukinumab exhibited a favorable safety profile similar to ustekinumab in an Asian population, and also consistent with the main trial results. Conclusion: Secukinumab provided superior efficacy over ustekinumab in clearing skin of Asian patients with moderate-to-severe plaque psoriasis. These results are consistent with the core study results (NCT02074982).