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Implementation Options and Economics of Phased UMTS Deployment
Grillo, Davide,Montagna, Maurizio,Alfano, Franco,Colombo, Antonio,Ricci, Simone The Korea Institute of Information and Commucation 2002 Journal of communications and networks Vol.4 No.4
3GPP (Third Generation Partnership Project) is defining UMTS (Universal Mobile Telecommunication System) releases which span the transition from GSM/UMTS coexistence to All-IP UMTS networks. The deployment of an UMTS network depends, in the first place, on the intended service offerings and the release an operator chooses to start service with. Other key decisions in-fluencing UMTS deployment relate to the timing of the functional enhancements and capacity increases along the economic life of the network. This paper gives an overview on the architectural and technical options for UMTS deployment. It also outlines the methodology underlying the business plan aimed at estimating the returns from investments in the UMTS infrastructure, thus helping to tune operators’ strategies for UMTS deployment.
Could Acupuncture Be Useful in the Treatment of Temporomandibular Dysfunction?
Ca´ssia Maria Grillo,Giancarlo De la Torre Canales,Ronaldo Seichi Wada,Marcelo Correˆa Alves,Ce´lia Marisa Rizzatti Barbosa,Fausto Berzin,Maria da Luz Rosa´rio de Sousa 사단법인약침학회 2015 Journal of Acupuncture & Meridian Studies Vol.8 No.4
In this study, the effects of acupuncture in comparison with flat occlusal plane appliance were evaluated in patient with myogenic temporomandibular dysfunction (TMD). The sample consisted of 40 women with TMD and unbalanced energy predominance of Yang Liver Ascension, selected using the Renying and Cunkou pulses, randomly divided into two groups: acupuncture and splint. The effect of treatments on the masseter and anterior temporal muscles was evaluated after 4 weeks of treatment, by means of electromyographic activity (root mean square) and pain pressure threshold. Pain intensity was measured using the visual analog scale, and range of mouth opening was evaluated using a millimeter ruler. All evaluations were performed at the beginning and end of the treatment. Visual analog scale score was reduced equally in the two groups (p < 0001), and the increase in range of mouth opening was significant in both groups. A significant difference was detected only in pain pressure threshold of the left masseter in the acupuncture group (p < 0.05). Only root mean square in the at rest position of the right temporal muscle diminished in the final stage of the splint group (p < 0.05). Both treatments reduced the pain intensity of myogenic TMD in the short term and may be considered strategies for control of chronic pain related to TMD.
Acupuncture in the Management of Acute Dental Pain
Ca´ssia Maria Grillo,Ronaldo Seichi Wada,Maria da Luz Rosa´rio de Sousa 사단법인약침학회 2014 Journal of Acupuncture & Meridian Studies Vol.7 No.2
Acute dental pain is the main reason for seeking dental services to provide urgent dental care; there is consensus about the use of alternative therapies, such as acupuncture, to control dental pain in pre-dental care. This study aimed to evaluate the use of acupunc- ture in reducing the intensity of acute dental pain in pre-dental care in patients waiting for emergency dental care, and was conducted at the After-Hours Emergency Dental Clinic of Piracicaba Dental School, and at the Emergency Center Dental Specialties I in Piracicaba, Sa ˜o Paulo, Brazil. The sample consisted of 120 patients. The Visual Analog Scale (VAS) was used to measure pain intensity. All patients underwent one session of acupuncture; the points LI4, ST44 and CV23 were selected and were used alone or in com- binations. Reduction in pain was observed in 120 patients (mean initial VAS = 6.558 ± 1.886, p < 0; mean final VAS= 0.962 ± 2.163, p < 0.00001). The results of this study indi- cate that acupuncture analgesia could be a technical adjunct to pain control in patients with acute dental pain, contributing to the restoration of health with social benefit.
Would a Placebo Acupuncture Needle be Able to Induce Deqi?
Ca´ssia Maria Grillo,Vera Lucia Rasera Zotelli,Maria Lu´cia Bressiani Gil,Maria da Luz Rosa´rio de Sousa 사단법인약침학회 2018 Journal of Acupuncture & Meridian Studies Vol.11 No.5
The aim of this study was to evaluate Deqi in patients under treatment with acupunctureand sham acupuncture. Forty (40) volunteers of all genders with temporomandibulardysfunction (TMD) were randomized into two study groups: Acupuncture and ShamAcupuncture (non-penetrating device). The patients answered the Southampton NeedleSensation Questionnaire (SNSQ) at the initial and final sessions of acupuncture treatment. The questionnaire was composed of two parts: the first one, consisting of 17 Deqi descriptorsand a Likert scale in order to evaluate the intensity of each sensation; and the secondone, consisting of a visual analog scale (VAS) to evaluate how painful the acupuncturetreatment was. At the initial session, LI4 was the most cited acupuncture point in bothgroups, being responsible for a ‘Slight Intensity’ needling sensation of electric shock inthe acupuncture group at initial (10%) and final (15%) sessions. The most common relatedneedling sensations at different acupuncture points was “Pricking” and “Sharp” in bothgroups. The acupuncture group showed higher VAS than the Sham Acupuncture eitherin the initial (3.87 2.43) and final (2.04 2.14) sessions. Deqi response to acupuncturestimulation was verified either in the both groups.
Surajit Pathak,Alessia Rosaria Grillo,Melania Scarpa,Paola Brun,Renata D’Incà,Laura Nai,Antara Banerjee,Donatella Cavallo,Luisa Barzon,Giorgio Palù,Giacomo Carlo Sturniolo,Andrea Buda,Ignazio Castagli 생화학분자생물학회 2015 Experimental and molecular medicine Vol.47 No.-
Abnormal levels of microRNA (miR)-155, which regulate inflammation and immune responses, have been demonstrated in the colonic mucosa of patients with inflammatory bowel diseases (IBD), although its role in disease pathophysiology is unknown. We investigated the role of miR-155 in the acquisition and maintenance of an activated phenotype by intestinal myofibroblasts (IMF), a key cell population contributing to mucosal damage in IBD. IMF were isolated from colonic biopsies of healthy controls, ulcerative colitis (UC) and Crohn’s disease (CD) patients. MiR-155 in IMF was quantified by quantitative reverse transcription-PCR in basal condition and following exposure to TNF-α, interleukin (IL)-1β, lipopolysaccharide (LPS) or TGF-β1. The effects of miR-155 mimic or inhibitor transfection on cytokine release and suppressor of cytokine signaling 1 (SOCS1) expression were assessed by enzyme-linked immunosorbent assay and western blot, respectively. Regulation of the target gene SOCS1 expression by miR-155 was assessed using luciferase reporter construct. We found that miR-155 was significantly upregulated in UC as compared with control- and CD-derived IMF. Moreover, TNF-α and LPS, but not TGF-β1 and IL-1β, significantly increased miR-155 expression in IMF. Ectopic expression of miR-155 in control IMF augmented cytokines release, whereas it downregulated SOCS1 expression. MiR-155 knockdown in UC-IMF reduced cytokine production and enhanced SOCS1 expression. Luciferase reporter assay demonstrated that miR-155 directly targets SOCS1. Moreover, silencing of SOCS1 in control IMF significantly increased IL-6 and IL-8 release. In all, our data suggest that inflammatory mediators induce miR-155 expression in IMF of patients with UC. By downregulating the expression of SOCS1, miR-155 wires IMF inflammatory phenotype.
Agenesis of the Internal Carotid Artery Associated with Generalized Epilepsy
Paolino La Spina,Francesco Grillo,Francesca Granata,Carmela Casella,Maria Carolina Fazio,Margherita Colella,Masina Cotroneo,Cristina Dell’Aera,Antonio Ciacciarelli,Giuseppe Vita,Rosa Musolino 대한신경과학회 2018 Journal of Clinical Neurology Vol.14 No.3
Annunziatella, M.,Bonamigo, M.,Grillo, C.,Mercurio, A.,Rosati, P.,Caminha, G.,Biviano, A.,Girardi, M.,Gobat, R.,Lombardi, M.,Munari, E. American Astronomical Society 2017 The Astrophysical journal Vol.851 No.2
<P>We present a high-resolution dissection of the two-dimensional total mass distribution in the core of the Hubble Frontier Fields galaxy cluster MACS J0416.1-2403, at z = 0.396. We exploit HST/WFC3 near-IR (F160W) imaging, VLT/Multi Unit Spectroscopic Explorer spectroscopy, and Chandra data to separate the stellar, hot gas, and dark-matter mass components in the inner 300 kpc of the cluster. We combine the recent results of our refined strong lensing analysis, which includes the contribution of the intracluster gas, with the modeling of the surface brightness and stellar mass distributions of 193 cluster members, of which 144 are spectroscopically confirmed. We find that, moving from 10 to 300 kpc from the cluster center, the stellar to total mass fraction decreases from 12% to 1% and the hot gas to total mass fraction increases from 3% to 9%, resulting in a baryon fraction of approximatively 10% at the outermost radius. We measure that the stellar component represents similar to 30%, near the cluster center, and 15%, at larger clustercentric distances, of the total mass in the cluster substructures. We subtract the baryonic mass component from the total mass distribution and conclude that within 30 kpc (similar to 3 times the effective radius of the brightest cluster galaxy) from the cluster center the surface mass density profile of the total mass and global (cluster plus substructures) dark-matter are steeper and that of the diffuse (cluster) dark-matter is shallower than an NFW profile. Our current analysis does not point to a significant offset between the cluster stellar and dark-matter components. This detailed and robust reconstruction of the inner dark-matter distribution in a larger sample of galaxy clusters will set a new benchmark for different structure formation scenarios.</P>
Kinematics of the SN Refsdal host revealed by MUSE: a regularly rotating spiral galaxy at z ≃ 1.5
Di Teodoro, E M,Grillo, C,Fraternali, F,Gobat, R,Karman, W,Mercurio, A,Rosati, P,Balestra, I,Caminha, G B,Caputi, K I,Lombardi, M,Suyu, S H,Treu, T,Vanzella, E Oxford University Press 2018 Monthly notices of the Royal Astronomical Society Vol.476 No.1
Patterns of Energy Imbalance of the Meridians in Patients with Temporomandibular Dysfunction
Vera L. Rasera Zotelli,Ca´ssia M. Grillo,Maria L. Bressiani Gil,Ronaldo S. Wada,Jorge E. Sato,Maria da Luz R. de Sousa 사단법인약침학회 2018 Journal of Acupuncture & Meridian Studies Vol.11 No.1
Temporomandibular dysfunction (TMD) is a set of changes that affects the muscles of mastication, temporomandibular joint, teeth, and associated periodontal and orofacial structures. According to Traditional Chinese Medicine, the imbalance of energy (Qi) circulating in the acupuncture meridians is always the primary etiologic cause of any physical manifestation. The aim of this study was to describe the patterns of Qi imbalance in patients with TMD by means of an objective measurement. The clinical study was conducted at the Piracicaba Dental School (FOP/Unicamp), in Piracicaba-SP, Brazil. We evaluated 40 adult volunteers with TMD. The Qi measurement was carried out by the researcher using the Ryodoraku method using 24 points representing the 12 acupuncture meridians: LU9 (Taiyuan), PC7 (Daling), HT7 (Shemen), SI5 (Yanggu), TE4 (Yangchi), LI5 (Yangxi), SP3 (Taibai), LR3 (Taichong), KI3 (Taixi), BL64 (Jinggu), GB40 (Qiuxu), and ST42 (Chongyang). The average total Qi of 40 volunteers (21.7 μA ± 1.5), was below the normal range (40–60 μA) and was classified as deficiency of Qi (empty). The coupled meridians that showed the highest Qi imbalance were the kidney (29.4 μA ± 2.8) and bladder (13.8 μA ± 1). The Qi planes with greatest imbalance were the Shao Yang and Shao Yin. In conclusion, volunteers with TMD presented a pattern of Qi deficiency, and the most prevalent imbalance patterns identified were in the kidney and bladder coupled meridians and in the energetic planes Shao Yin (heart/kidney) and Shao Yang (triple energizer/gall bladder).