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Rosana Goldbeck,Francisco Maugeri Filho 한국식품과학회 2013 Food Science and Biotechnology Vol.22 No.suppl1
The main goal of this work was to select and characterize lipase producing wild yeasts isolated from different biomes of Brazil. A total of 372 wild yeasts were tested for their lipase producing potential and 3 strains were selected and characterized according to their substrate specificity, pH, and temperature effects and biocatalytic capacity for synthesis in organic media. For the AC02strain, the optimal enzymatic conditions were pH 7.0 and temperature 44ºC, whilst for AAV1 strain, pH 7.0 was also better, but the optimal temperature was 47ºC, and for AY3strain the optimal temperature was 37ºC and pH 6.6. About substrate specificity, the lipase from AY3 strain showed higher specificity for short-chain triglycerides. The AC02strain showed the highest lipolytic activity among the 3selected, and was molecularly identified by sequencing the ITS1-5.8S-ITS2 and D1/D2 domains of the subunit (26 S)ribosomal DNA as Metschnikowia pulcherrima.
Association of Lower Socioeconomic Status and SARS-CoV-2 Positivity in Los Angeles, California
Allan-Blitz Lao-Tzu,Goldbeck Cameron,Hertlein Fred,Turner Isaac,Klausner Jeffrey D. 대한예방의학회 2021 Journal of Preventive Medicine and Public Health Vol.54 No.3
Objectives: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreads heterogeneously, disproportionately impacting poor and minority communities. The relationship between poverty and race is complex, with a diverse set of structural and systemic factors driving higher rates of poverty among minority populations. The factors that specifically contribute to the disproportionate rates of SARS-CoV-2 infection, however, are not clearly understood. Methods: We evaluated SARS-CoV-2 test results from community-based testing sites in Los Angeles, California, between June and December, 2020. We used tester zip code data to link those results with United States Census report data on average annual household income, rates of healthcare coverage, and employment status by zip code. Results: We analyzed 2 141 127 SARS-CoV-2 test results, of which 245 154 (11.4%) were positive. Multivariable modeling showed a higher likelihood of SARS-CoV-2 test positivity among Hispanic communities than among other races. We found an increased risk for SARS-CoV-2 positivity among individuals from zip codes with an average annual household income <US$65 000 (adjusted odds ratio [aOR], 1.77; 95% confidence interval [CI], 1.72 to 1.82), as well as from zip codes with <85% of individuals with health insurance (aOR, 1.29; 95% CI, 1.25 to 1.33), and <60% of individuals employed (aOR, 1.42; 95% CI, 1.41 to 1.44). Conclusions: Residence in zip codes with lower average annual household income, lower rates of employment, or lower rates of health insurance was associated with SARS-CoV-2 positivity. Further research is needed into how those factors increase the spread of SARS-CoV-2 infection among populations of lower socioeconomic status in order to develop targeted public health interventions.