심한 하악골 전돌증 환자의 외과적 치험례

권대근,이상한,이근호,장도근 大韓顎顔面成形再建外科學會 1994 Maxillofacial Plastic Reconstructive Surgery Vol.16 No.1

Obwegeser Ⅱ method and Rigid fixation conserving the condylar position has been performed on 5 patients with severe mandibular prognathism, and we obtained the result after the follow up study follows. 1. Obwegeser Ⅱ method is considered to move the distal segment passively when surgical correction of severe open bite correction and large amount of set back above 15mm is needed. 2. In one case that has more change of condylar position after operation, documented immediate post- operative relapse have been occurred 3. In the others that have adequate control of condylar position, passive set back and firm skeletal fixation, more functional and esthetic improvement and more post-operative stability has been achieved

Magnetic Resonance Imaging: Historical Overview, Technical Developments, and Clinical Applications

Jahng, Geon-Ho,Park, Soonchan,Ryu, Chang-Woo,Cho, Zang-Hee Korean Society of Medical Physics 2020 의학물리 Vol.31 No.3

The authors congratulate the cerebrations for the 30 years of the Korean Society of Medical Physics (http://www.ksmp.or.kr/). The paper is published to recognize the anniversary. Geon-Ho Jahng invited Professor Z. H. Cho to join to submit this manuscript because he has been one of the leaders in the field of magnetic resonance imaging (MRI) during the last 40 years. In this review, we describe the development and clinical histories of MRI internationally and domestically. We also discuss diffusion and perfusion MRI, molecular imaging using MRI and MR spectroscopy (MRS), and the hybrid systems, such as positron emission tomography-MRI (PET-MRI), MR-guided focused ultrasound surgery (MRgFUS), and MRI-guided linear accelerators (MRI-LINACs). In each part, we discuss the historical evolution of the developments, technical developments, and clinical applications.

The Antioxidant Effect of the Rhaponticum uniflorum Extracts on the Oxidative Stress in H₂O₂ induced Human Keratinocytes

So Hee Ahn,Won Yeoung Choi,Ji Won Jeong,Geon Woo Park,Su Yeon Kang,Eun Jeong Kim,Su Rim Sin,Eun Seo Jang,Gye Won Lee,Young Ho Cho 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10

In this study, To investigate the antioxidant activities of Rhaponticum uniflorum extracts (RUE), we assessed scavenging activities on DPPH, ABTS radicals, and reducing power. The DPPH and ABTS radical scavenging activities (SC50) of RUE were 96.97±1.19 μg/mL and 31.26±0.13 μ g/mL, respectively, and the reducing power significantly increased dose-dependent manner. To study the antioxidant effecters of RUE in H₂O₂ induced human keratinocytes, expression of Nuclear factor erythroid-2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1) were determined by Western blot and qRT-PCR. RUE induced the expression of HO-1, a critical target enzyme of Nrf2, in a concentration-dependent manner. The expression of HO- 1 mRNA was also induced in H₂O₂-treated HaCaT cells but no significant difference in the level of HO-1 mRNA was observed. Taken together, these results suggest that RUE may be useful as a potential ingredient for anti-aging products.

정신분열증 입원환자에서 니코틴과 항정신병 약물의 상관관계 규명을 위한 니코틴 패취 적용 연구

반건호,유희정,윤도준,김종우,이기철 대한생물치료정신의학회 2000 생물치료정신의학 Vol.6 No.1

연구목적 : 정신분열증 환자는 흡연율이 높고, 그에 따라 항정신병 약물 투여량이 늘어나고, 약물에 의한부작용은 오히려 감소한다고 알려져 있다. 이러한 연구에서 방법론적 문제로는 실제 니코틴 용량을 측정하지 않았다는 점이다. 본 연구는 담배보다 니코틴의 주요 대사물인 코티닌을 측정하여 방법론적 오류를 최소화하고자 하였다. 방법 : 정신분열증으로 진단받은 입원환자 중 니코틴 패취군 8명, 대조군 8명을 설정하였다. 5일간 패취를 붙인 후 혈액에서 코티닌을 측정하였고, 정신증상의 정도를 알기 위하여 PANSS, 약물의 추체외로 부작용 측정을 위하여 ESRS를 실시하였다 일일 약물용량을 chlorpromazine 동량으로 환산하여 기록하였다. 결과 : 코티닌 수치와 정신증상, 추체외로부작용, 약물용량 사이에는 유의한 차이가 없었다. 결론 : 코티닌은 항정신병 약물의 작용에 영향을 미치지 못하였다. 단, 향후 연구에서는 니코틴 패취의 양을 증량하여 사용하므로써, 코티닌 용량에 따라 항정신병 약물효과에 영향을 미칠 수 있는지를 검증해야 할 것이다.

절연 파괴 특성을 이용한 에폭시 복합체의 절연 신뢰도 예측

박건호,이준웅 광운대학교 신기술연구소 1996 신기술연구소논문집 Vol.25 No.-

본 연구에서는 송배전 계통에서 변성기의 몰드 재료로서 널리 사용되고 있는 에폭시 수지를 시료로 하여 설정해 높은 배합비에 따라 5종으로 제작한 각 시편에 대해 절연 파괴 실험을 하였다. 절연파괴 데이터를 가지고 와이블 분포식을 이용하여 임의의 허용 파괴 확률에서의 허용인가 전계의 값을 추정하였으며 절연 안전성을 판단하기 위하여 경년 열화(經年劣化) 데이터의 통계 처리를 행한 결과 허용 파괴 확률을 0.1[%]로 하였을 때, 허용 인가 전계는 21.5[kV/mm] 이하가 되어야 함을 확인할 수 있었다. In this study, the dielectric breakdown of epoxy composites used for transformers was experimented and then its data were simulated by Weibull distribution probability. The more hardener increased the stronger breakdown strength at low temperature because of cross-linked density by the virtue of ester radical, and the breakdown strength of specimens with filler was lower than it of non-filler specimens because it is believed that the adding filler forms interface and charge is accumulated in it, therefore the molecular motility is raised, the electric field is concentrated, and the acceleration of electron and the growth of electron avalanche are early accomplished. From the analysis of Weibull distribution, it was confirmed that as the allowed breakdown probability was given by 0.1[%], the applied field value needed to be under 21.5[kV/mm].

자해

반건호,강윤형,박태원,이은정,표경식 漢陽大學校 精神健康硏究 2000 精神健康硏究 Vol.19 No.-

성인에서의 주의력결핍·과잉행동장애

반건호,조아랑 경희대학교 2002 慶熙醫學 Vol.18 No.3-4

항암제 투여가 이식된 가토 유리자가골의 치유에 미치는 영향

이근호,장현중 慶北大學校 齒科大學 1993 慶北齒大論文集 Vol.10 No.2

저자는 가토 16마리를 사용하여 하악골편을 절제하여 재이식한 후 7일째 대조군 8마리에 생리식염수 5cc를 정주하고 실험군 8마리에 체중 1kg당 Cisplatin 2mg과 5-Fluo- ruracil 40mg을 정주한 후에서 각각 3, 7, 14, 21일째 군별로 2마리씩 희생시켜 이식골의 치유과정을 조직학적으로 비교 관찰하여 다음과 같은 결과를 얻었다. 1. 투약후 3일(이식후 10일)째 이식된 골조직내의 세포는 생활력을 나타내며 골간극에는 신생골주가 형성되었다. 2. 투약후 7일째 형성된 골소주에 의해 수용체와 이식골이 유합되기 시작하여 투약후 14일째 대부분에서 골성유합이 완성되었어며 투약후 21일째에는 재형성과정이 진행되었다. 3. 투약후 각 기간별로 대조군과 실험군에서 명확한 차이는 없었다. The purpose of this study is to investigate the effect of antineoplastic agents on the healing process of free autogenous bone graft to reconstruct mandible immediately after tumor resection. Sixteen rabbits, resected and replanted a part of mandible, were divided into two groups. The eigth experimental rabbits were administrated cisplatin 2mg and 5-fluorouracil 40mg per kg of body weight, and the eight controls were administrated normal saline 5cc on postoperation 7 days. Each of them was sacrified 3,7,14 and 21 days after administration of drugs. Specimens were obtained and processed in a routine manner for H-E stain. After light microscopic examination, following results were obtained. 1. In 3 days after administration of chemotherapic agents, the cell in the graft showed vitality, and new trabecular bone was formed in the gap between host and graft bone. 2. In 7 days after administration, bony union between host bed and graft by new-formed trabecular bone was appeared, and in 14 days achieved almost. In 21 days, remodeling process was appeared. 3. There was no significant difference between experimental and control groups.

지수분포를 따르는 가속수명자료의 최우추정법에 기초한 경험적 베이즈 예측분석

조건호,이우동,하일도 慶山大學校 基礎科學硏究所 1997 基礎科學 Vol.1 No.2

본 논문은 지수수명분포에서 제2종 중도절단된 가속수명자료를 이용하여 고장률의 사전분포의 평균을 알 때, 정상조건하에서 하나의 미래 관찰치의 예측문제를 사전분포의 모수에 대하여 최우추정량(Maximun Likelihood estimator)을 이용하는 경험적 베이즈 접근방법을 적용시켜 경험적 베이즈 예측분포와 예측구간에 대하여 연구하였다. In accelerated life tests(ALTs), the failure time of a test item is observed under high stress conditions, and based on these data, one intrests statistical inference on the parameters of lifetime distribution at the normal stress. Under the type-II censoring, we assume that the life distribution is exponential distribution. When the information on the prior is partially known, we device the empirical Bayesian analysis of ALTs data in order to obtain the empirical Bayesian predictive density and predictive intervals for a future observation under the normal stress level.

유소아의 반복행동. 습관인가 정신병리인가?

반건호,김태 경희대학교 2002 慶熙醫學 Vol.18 No.3-4