http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Gürses (검색결과 4 건)
- 무료
- 기관 내 무료
- 유료
-
Teratogenicity of Antiepileptic Drugs
Betül Tekin Güveli,Rasim Özgür Rosti,Alper Güzeltaş,Elif Bahar Tuna,Dilek Ataklı,Serra Sencer,Ensar Yekeler,Hülya Kayserili,Ahmet Dirican,Nerses Bebek,Betül Baykan,Ayşen Gökyiğit,Candan Gürses 대한정신약물학회 2017 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.15 No.1
Objective: Antiepileptic drugs (AED) have chronic teratogenic effects, the most common of which are congenital heart disease, cleft lip/palate, urogenital and neural tube defects. The aim of our study is to examine teratogenic effects of AED and the correlation between these malformations and AED in single or multiple pregnancies. Methods: This is a retrospective study of malformations in children born to mothers currently followed up by our outpatient clinics who used or discontinued AED during their pregnancy. Their children were then investigated using echocardiography, urinary ultrasound, cranial magnetic resonance image, and examined by geneticists and pediatric dentists. Results: One hundred and seventeen children were included in the study. Ninety one of these children were exposed to AED during pregnancy. The most commonly used AED were valproic acid and carbamazepine in monotherapy. The percentage of major anomaly was 6.8% in all children. Dysmorphic features and dental anomalies were observed more in children exposed especially to valproic acid. There were 26 mothers with two and four mothers with three pregnancies from the same fathers. No correlation was found between the distribution of malformations in recurring pregnancies and AED usage. Conclusion: Our study has the highest number of dysmorphism examined in literature, found in all the children exposed to valproic acid, which may account for the higher rate of facial dysmorphism and dental anomalies. On lower doses of valproic acid, major malformations are not seen, although the risk increases with polytherapy. Our data also indicate possible effects of genetic and environmental factors on malformations.
-
Elçin Demirhan,Büşra Gürses,Bengi Ece Yalçin,Dilek Kiliç Apar,Belma Özbek 한국식품과학회 2013 Food Science and Biotechnology Vol.22 No.4
The aim of the present study was to investigate the effects of additions of various vitamins (B1, B6, B9, B12,and C) and minerals (CuSO4·H2O, MnSO4·H2O, and Na3PO4·12 H2O) on the propagation of kefir grains. The activated kefir grains were inoculated into very low fat (0.1%) cows’ milk under constant temperature (25oC) and impeller speed (100 rpm) for a propagation time of 24 h. After evaluation of the experimental data, the most influential mineral addition providing 39% increase of kefir grain biomass was found to be Na3PO4·12 H2O with a concentration of 0.30 g phosphate (PO43−) ion/L. At this optimal condition, a model was also derived for the kefir grain biomass concentration representing pH dependence. This study demonstrated the basis for further research in the direction of kefir grain biomass growth considering the effect of additions of vitamins and minerals to other researchers working in the same field and to dairy industry as well.
-
Effectiveness of Pregabalin for Treatment of Burning Mouth Syndrome
Saliha Yeter Amasyalı,Aslı Akyol Gürses,Osman Nuri Aydın,Ali Akyol 대한정신약물학회 2019 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.17 No.1
Treatment of burning mouth syndrome (BMS) is challenging because there is no consensus regarding pharmalogical or nonpharmalogical therapies. The use of anticonvulsants is controversial. We present nine patients BMS who respond to pregabalin. They were diagnosed secondary BMS except two. Etiologic regulations were made firstly in patients with secondary BMS but symptoms did not decrease. We preferred pregabalin in all patients and got good results. Furthermore the addition of pregabalin to the treatment of two patients who did not respond adequately to duloxetine provided good results. We are only aware that pregabalin may reduce symptoms as a result of case reports. We believe that the diagnosis of pathologic etiology with appropriate diagnostic tests will result in better outcomes in treatment.
-
First extensor compartment morphology and clinical significance: a cadaver series study
Osman Coşkun,Fatma Ok,Büşra Şahin,İlke Ali Gürses 대한해부학회 2023 Anatomy & Cell Biology Vol.56 No.3
The first extensor compartment of the wrist is a distinctly variable anatomical area. Anatomical variations in thisregion contribute to the pathophysiology and treatment failure of de Quervain’s disease, which is a kind of tenosynovitis that develops in the first extensor compartment of the wrist. We aim to describe the first extensor compartment morphology, to evaluate the septum frequency, location of the septum, and the number of tendons of abductor pollicis longus (APL) and extensor pollicis brevis muscles (EPB). First extensor compartment of 87 wrists of 45 cadavers were dissected. The presence or absence of septum and number of tendon slips of APL and EPB revealed. The proximal and distal widths of the compartments were measured. Septums were detected in 60.9% (n=53) of the wrists. Incomplete (distal) and complete (proximal) septa were present in 35.6% (n=31) and 25.3% (n=22) of the cases. Only 26.4% of the wrists had a single slip of APL tendon. The Remaining had multiple slips. The median inner width of the proximal and distal compartments in all wrists were calculated as in the order of 9.11±1.14 mm and 8.55±1.12 mm. We believe that understanding the anatomy of the first extensor compartment in the Turkish population would be helpful to surgeons, radiologists, and physiotherapists to diagnose and manage de Quervain’s disease.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
