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      • KCI등재후보

        Inheritance and Development of Cultural Heritage of Chinese Architecture

        Liu, Fu-long 사단법인 한국조형디자인협회 2013 조형디자인연구 Vol.16 No.4

        Chinese traditional architecture has a long-dated history. As one of the important architectural style of ancient cultural heritage, archway (square) building used since the Song Dynasty and now is the crowning touch to the composition of architectural space. First, the value of the arch is embodied in the inheritance and development of traditional culture, and cultural development of the arch is closely related to historical and cultural background of Chinese society; Second, as a traditional architectural form, the arch is one of the unique elements in entrance spaces, such as villages, temples, towns, royal gardens, memorial sites, tombs, etc. Meanwhile, the arch has become typical symbol of the entrance to residential area of foreign Chinese. Column, floor and frontal fang and span arch is the basic components of the arch.To cleverly constructed so that the arch stand leaving it emerged actual situation and white silhouette beauty. We can learn construction techniques and layout forms of Chinese traditional architecture, then explore the inheritance and development of the wisdom and culture of Chinese traditional architecture under contemporary perspective though the arch arts. The article takes the design of Baoji City Dai Jia-wan administrative square arch for example, explores the way of combining new technologies with traditional materials, meanwhile achieves harmony between large-scale pure stone arch and contemporary urban space, which is a useful practice about inheritance and innovation of traditional arch arts.

      • KCI등재

        Inheritance and Development of Cultural Heritage of Chinese Architecture - Root-Exploring and Innovation of the Cultural Value of the Arch

        Liu,Fu-long 한국조형디자인학회 2013 조형디자인연구 Vol.16 No.4

        Chinese traditional architecture has a long-dated history. As one of the important architectural style of ancient cultural heritage, archway (square) building used since the Song Dynasty and now is the crowning touch to the composition of architectural space. First, the value of the arch is embodied in the inheritance and development of traditional culture, and cultural development of the arch is closely related to historical and cultural background of Chinese society; Second, as a traditional architectural form, the arch is one of the unique elements in entrance spaces, such as villages, temples, towns, royal gardens, memorial sites, tombs, etc. Meanwhile, the arch has become typical symbol of the entrance to residential area of foreign Chinese. Column, floor and frontal fang and span arch is the basic components of the arch. To cleverly constructed so that the arch stand leaving it emerged actual situation and white silhouette beauty. We can learn construction techniques and layout forms of Chinese traditional architecture, then explore the inheritance and development of the wisdom and culture of Chinese traditional architecture under contemporary perspective though the arch arts. The article takes the design of Baoji City Dai Jia-wan administrative square arch for example, explores the way of combining new technologies with traditional materials, meanwhile achieves harmony between large-scale pure stone arch and contemporary urban space, which is a useful practice about inheritance and innovation of traditional arch arts.

      • Changes in Markers of Liver Function in HCV 1b Patients with Compensated Cirrhosis Treated with Ombitasvir/Paritaprevir/ Ritonavir plus Dasabuvir with Ribavirin

        ( Jeong Heo ),( Yan Luo ),( Wan-long Chuang ),( Jidong Jia ),( Kwang-hyub Han ),( Ming-lung Yu ),( Hong Tang ),( Young-suk Lim ),( Cheng-yuan Peng ),( Min Xu ),( Maorong Wang ),( Bo Fu ),( Niloufar Mo 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

        Aims: Patients chronically infected with HCV are at risk of developing extrahepatic manifestations of HCV as well as progressing to compensated or decompensated cirrhosis and HCC. Although current treatments have high rates of SVR, relatively little is known about possible regression of liver fibrosis after achieving an SVR. The ONYX-II trial examined the efficacy and safety of ombitasvir/paritaprevir/ritonavir plus dasabuvir + ribavirin (RBV) in Asian patients with HCV genotype 1b infection and compensated cirrhosis. Here we report changes in key markers of liver fibrosis and function. Methods: Patients with chronic HCV GT1b infection and compensated cirrhosis were enrolled in China, South Korea and Taiwan and received 12 weeks of OBV/PTV/r (25 mg/150 mg/100 mg once daily) and DSV (250 mg twice daily) with weight-based RBV. The primary objective of ONYX-II was to assess efficacy (SVR12) and safety of the regimen. Changes in markers of liver fibrosis and function between baseline (BL) and post-treatment week (PTW) 12 are presented. Results: Overall, 104 patients were enrolled and treated in ONYX-II. All patients (104/104, 100%) achieved SVR12. BL and PTW12 data for FibroTest score, alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin, albumin, platelet count and alpha fetoprotein (AFP) are shown in Table 1. All selected parameters showed numerical improvements between BL and PTW12. Mean ALT and AST levels returned to within normal range and FibroTest scores demonstrated a numerical improvement, suggesting improvement in liver status. The complete set of data between BL and PTW12 will be presented for these parameters and other liver composite parameters at the conference. Conclusions: Measurement of key liver function markers during the ONYX-II trial showed a numerical improvement within 12 weeks of completion of treatment in HCV GT1b-infected patients with compensated cirrhosis. Further follow-up of these patients will determine the long-term durability of these changes.

      • KCI등재후보

        한국인 및 중국 한족 정신분열병 환자의 5-HT2A 수용체 유전자 -1438A/G 다형성

        이장호,이광철,이승부,오용인,최영근,조아랑,정주호,장환일 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.1

        Objectives : The purpose of the present study was to investigate the association between -1438A/G polymorphism of 5-HT2A receptor gene and schizophrenia in Korean and Han Chinese population. Methods : A sample of 184 Korean patients with schizophrenia and 96 Korean healthy normal controls and 96 Han Chinese patients with schizophrenia and 96 Han-Chinese healthy normal controls were genotyped for a single nucleotide polymorphism with in 5-HT2A receptor gene (promoter region, A-1438G) by Msp I Resthction Fragment Length Polymorphism (RFLP). Results : There was no difference in allelic frequencies and genotype frequencies of -1438A/G polymorphism between Korean schizophrenics and controls (p=0.13) and Han Chinese schizophrenics and controls (p=0.40). Also, -1438A/G Poly-morphism did not show ethnical difference between Korean and Han Chinese controls. The Scale for the Assessment of Negative Symptoms (SANS) scores showed no significant differences between genotypes of -1438A/G polymorphism in both of Korean and Han Chinese schizophrenics. Conclusion : These results suggest that -1438A/G polymorphism of the 5-HT2A receptor gene is not causally related to the development of schizophrenia in Korean and Han Chinese population, and there no ethnic difference between Korean and Han Chinese population.

      • KCI등재

        Comparative proteomic analysis of parasitic loranthus seeds exposed to dehydration stress

        Limei Pan,Lingyun Wan,Lili He,Lisha Song,Hairong Long,Xiaowen Ji,Ni Jiang,Juan Huo,Shugen Wei,Jine Fu 한국식물생명공학회 2021 Plant biotechnology reports Vol.15 No.1

        Parasitic loranthus [Taxillus chinensis (DC.) Danser] is an important medicinal plant that produces recalcitrant seeds that are sensitive to dehydration. Desiccation tolerance is critical for the survival of recalcitrant seeds in low-moisture environments. Clarifying how these seeds respond to desiccation is important for long-term conservation. Thus, the viability, germination, microstructure, and antioxidant enzyme activities of dehydrated parasitic loranthus seeds were investigated. Diverse organelles were degraded or deformed during dehydration treatments. Additionally, superoxide dismutase and catalase activities gradually decreased in response to desiccation stress. A proteomic analysis involving TMT-labeling and LC–MS/ MS were performed. A total of 1479 proteins were identifed, of which 141 were diferentially expressed proteins (DEPs) at 16 and 36 h after initiating the dehydration treatments. A functional annotation based on gene ontology revealed that the DEPs were mainly localized in chloroplasts and were related to energy metabolism, responses to stimuli, and the regulation of biological processes. A KEGG pathway enrichment analysis determined that several of the identifed proteins were associated with signal transductions, photosynthesis, and glycolysis/gluconeogenesis. The results suggest that the efcient removal of excessive ROS amounts may be crucial for promoting parasitic loranthus seed germination under dehydration stress conditions. A series of candidate dehydration stress-related proteins were identifed and may be relevant for enhancing the dehydration tolerance of the recalcitrant seeds. To the best of our knowledge, this is the frst study to elucidate the possible molecular mechanisms underlying the sensitivity of recalcitrant parasitic loranthus seeds to dehydration via a proteomic analysis involving TMT-labeling.

      • Teachers’ Collaborative Professional Development Model through Video Analysis Methods-Design Based Research in 2011~2012

        Fu Long 한양대학교 교육공학연구소 2013 학습과학연구 Vol.7 No.2

        This article describes a teacher’s professional development model based on collaborative learning theory and video reflective club experiences. 408 teachers of all subjects joined our program and 113 of them upload their videos for discussion and reflections. We are doing this research in a real-life environment with multiple variables, and have to adopt design based research as methodology. At the very beginning we put up a VOD platform and quantitative analysis results for teachers to make their discussion; then we keep collecting filed notes, patch flaws and add elements that might work. After 3 iterations, the author summarized all the positive effect and simplified the whole process into a cycling model. Which uses teachers’ real-life classroom video as media, video analysis as scaffold, online discussion as main activity, reflection as guarantee, and trying to make them redesign their instructional design as a continuous process.

      • KCI등재

        Seismic Active Earth Pressure of Infinite Width Backfilled Soil on Cantilever Retaining Wall with Long Relief Shelf under Translational Mode

        Yun Que,Cheng-cheng Long,Fu-Quan Chen 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.8

        In the area of high seismic intensity, there were few methods for calculating active earth pressure (Ea). Especially for the cantilever retaining wall with long relief shelf (CRW-LRS), the theoretical method lags behind the practical engineering. The seismic active earth pressure (Es) of the CRW-LRS subject to translational mode was researched. By finite element method (FEM), the failure mode of the active limit state under seismic load was evaluated. The results show that the backfill behind the wall generates the first sliding surface at the wall heel bottom, the second at the wall heel top, and the third at the relief shelf top. The calculation formula of Es under long relief shelf failure mode was proposed using the limit analysis method of a horizontal differential layer. The calculation results were compared with the FEM results to prove the rationality and reliability of the theoretical solution. The effects of relief shelf relative length (l) and position (m), wall heel length (n), internal frictional angle of the backfill (ϕ), seismic horizontal acceleration (ah), and seismic vertical acceleration (av) on Es were studied.

      • KCI등재

        Sliding Mode Control of Three-Phase Four-Leg Inverters via State Feedback

        Long-Yue Yang,Jian-Hua Liu,Chong-Lin Wang,Gui-Fu Du 전력전자학회 2014 JOURNAL OF POWER ELECTRONICS Vol.14 No.5

        To optimize controller design and improve static and dynamic performances of three-phase four-leg inverter systems, a compound control method that combines state feedback and quasi-sliding mode variable structure control is proposed. The linear coordinate change matrix and the state variable feedback equations are derived based on the mathematical model of three-phase four-leg inverters. Based on system relative degrees, sliding surfaces and quasi-sliding mode controllers are designed for converted linear systems. This control method exhibits the advantages of both state feedback and sliding mode control. The proposed controllers provide flexible dynamic control response and excellent stable control performance with chattering suppression. The feasibility of the proposed strategy is verified by conducting simulations and experiments.

      • KCI등재

        Microstructural Evolution and Mechanical Properties of a Continuously Cast Al–Mg–Si–Cu Alloy Processed by Repetitive Continuous Extrusion Forming

        Long Zhang,Ruiqing Lu,Jie Tang,Fulin Jiang,Dingfa Fu,Hui Zhang,Jie Teng 대한금속·재료학회 2023 METALS AND MATERIALS International Vol.29 No.7

        A continuously cast Al–Mg–Si–Cu alloy was processed by repetitive continuous extrusion forming (R-Conform) and thecorresponding deformation behaviors, microstructural evolution and mechanical properties were investigated systematicallyby combining uniaxial compression deformation, finite element simulation, microstructural observation and mechanicaltest. The results showed that the grain size of Al–Mg–Si–Cu alloy bar was gradually refined and became more uniformafter R-Conform processing with the increase of pass as a result of continuous dynamic recrystallization. The evolution ofmicrostructure was related to the complex thermomechanical conditions of temperature, shear rate and the distribution ofaccumulated strain during R-Conform process. Then the improvement of properties was obtained by the refined grains afterR-Conform processing. Further, the dense and fine precipitates formed after solution treatment and aging led to optimizedmechanical properties with tensile strength approximate 400 MPa and elongation about 17.8%.

      • KCI등재

        Collateral Flow in Magnetic Resonance Angiography: Prognostic Value for Vertebrobasilar Stenosis With Stroke Recurrence

        Long Yan,Ying Yu,Kaijiang Kang,Zhikai Hou,Min Wan,Weilun Fu,Rongrong Cui,Yongjun Wang,Zhongrong Miao,Xin Lou,Ning Ma 대한신경과학회 2022 Journal of Clinical Neurology Vol.18 No.5

        Background and Purpose Intracranial vertebrobasilar atherosclerotic stenosis (IVBAS) is a major cause of posterior circulation stroke. Some patients suffer from stroke recurrence despite receiving medical treatment. This study aimed to determine the prognostic value of a new score for the posterior communicating artery and the P1 segment of the posterior cerebral artery (PCoA-P1) for predicting stroke recurrence in IVBAS. Methods We retrospectively enrolled patients with severe IVBAS (70%–99%). According to the number of stroke recurrences, patients were divided into no-recurrence, single-recurrence, and multiple-recurrences groups. We developed a new 5-point grading scale, with the PCoA-P1 score ranging from 0 to 4 based on magnetic resonance angiography, in which primary collaterals were dichotomized into good (2–4 points) and poor (0 or 1 point). Stroke recurrences after the index stroke were recorded. Patients who did not experience stroke recurrence were compared with those who experienced single or multiple stroke recurrences. Results From January 2012 to December 2019, 176 patients were enrolled, of which 116 (65.9%) had no stroke recurrence, 35 (19.9%) had a single stroke recurrence, and 25 (14.2%) had multiple stroke recurrences. Patients with single stroke recurrence (odds ratio [OR]= 4.134, 95% confidence interval [CI]=1.822–9.380, p=0.001) and multiple stroke recurrences (OR=6.894, 95% CI=2.489–19.092, p<0.001) were more likely to have poor primary collaterals than those with no stroke recurrence. Conclusions The new PCoA-P1 score appears to provide improve predictions of stroke recurrence in patients with IVBAS

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