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C1–C3 Lateral Mass Screw-Rod Fixation and Fusion for C2 Pathologies and Hangman’s Fractures
Forhad Hossain Chowdhury,Mohammod Raziul Haque 대한척추외과학회 2014 Asian Spine Journal Vol.8 No.6
Study Design: Retrospective clinical study. Purpose: We report our experience of eight patients treated with C1–C3 lateral mass rod-screw stabilization and fusion in the treatment of Hangman’s fracture and other axis pathologies. Overview of Literature: Different surgical approaches, both anterior and posterior, have been described for treating Hangman’s fracture and other pathologies where surgery is indicated. Methods: All patients who underwent surgical treatment for Hangman’s fracture and axial pathology where C1–C3 lateral mass screw-rod stabilization and fusion done, following reduction of the fracture or removal of the pathology were included in this series. The recorded patient management data was retrospectively studied. Results: There were 8 cases in total. All were male, with an average age of 40.75 years. Hangman’s fracture occurred in 6 cases (75%), one with metastatic squamous cell carcinoma and the remaining with plasmocytoma. Among the Hangman’s fractures 4 (66.66%) had no neuro-deficit. Reduction and bilateral C1–C3 lateral mass screw and rod fixation with posterior fusion by bone graft was performed in all cases. In 2 cases, a C2 body tumor was removed transorally. All patients with neuro-deficit fully recovered, except one who expired in the early post-operative period. Rest of all patients were leading a normal life till last follow up. Conclusions: Although the number of cases was very small with a relatively short follow up period, C1 and C3 lateral mass screwrod fixation followed by fusion showed promise as an effective and biomechanically sound way for the treatment of properly selected Hangman’s fracture cases, and may also be suitable in other axial pathologies.
Insights into the in vitro germicidal activities of Acalypha indica
Rahman, Md. Shahedur,Hossain, Riad,Saikot, Forhad Karim,Rahman, Shaikh Mizanur,Saha, Subbroto Kumar,Hong, Jongki,Kim, Ki-Hyun The Korean Society of Analytical Science 2017 분석과학 Vol.30 No.1
Background and purpose: This study was carried out to learn more about the potential prophylactic or antibacterial activity of the plant Acalypha indica against selective pathogenic bacteria. Experimental: The test organisms were Sarcina lutea IFO 3232, Bacillus subtilis IFO 3026, Pseudomonas denitrificans, Escherichia coli IFO 3007, Klebsiella pneumoniae ATTC 10031, Xanthomonas campestris IAM 1671, and Proteus vulgaris. Leaf, stem, and bud powder of Acalypha indica were dissolved in various solvents, and the extracts were tested for antimicrobial activity through the disc diffusion method. GC-MS profiling was performed to characterize active chemical compounds in the essential oil of Acalypha indica. Results: The ethanol extract showed the highest activity against all bacteria, while the petroleum ether extract yielded the highest zone of inhibition against Proteus vulgaris ($11.83{\pm}1.75mm$). The minimum inhibitory concentration (MIC) of the ethyl acetate extract against Bacillus subtilis was 16 µg/mL. Phytochemical screening by GC-MS revealed a total of 12 bioactive compounds. Conclusion: Extracts of Acalypha indica may be useful in formulating and synthesizing new antibacterial drugs.