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Fengzhi Li 한국분자세포생물학회 2009 Molecules and cells Vol.27 No.4
We present the result of our research on the tumorigenic ability of single cell clones isolated from an aggressive murine breast cancer cell line in a matched allografting mouse model. Tumor formation is basically dependent on the cell numbers injected per location. We argue that in vivo tumor formation from single cell clones, isolated in vitro from cancer cell lines, may not provide conclusive evidence to disprove the cancer stem cell (CSC) theory without additional data.
Fengzhi Shi,Chengyi Zhao,Xu Zhou,Xinhu Li 한국기상학회 2019 Asia-Pacific Journal of Atmospheric Sciences Vol.55 No.2
The interaction between climate change trends and water cycle variables is complex. The spatial distributions and trends of hydroclimatic variables (precipitation, temperature, water vapor pressure, and relative humidity) at 65 stations in Xinjiang in 1961–2011 were analyzed. Five meteorological stations were selected for a detailed analysis of the changes in climatic factors. We explored the relationship between water vapor pressure, relative humidity, temperature, and precipitation using nonparametric methods [the block bootstrap (B-B) method, Mann-Kendall (MK) test, and a generalized additive model (GAM)] for data from 1940 to 2011. The results showed that temperature, precipitation, and water vapor pressure at most stations increased over the period studied, while relative humidity decreased in the north of Xinjiang, and increased in the south. The results indicated that the temperature and water vapor pressure were elevated. At the same time, there was a large spatiotemporal heterogeneity of precipitation and relative humidity among the five stations. The water vapor pressure had a significant positive relationship with temperature and relative humidity, but the temperature trend with relative humidity displayed a negative relationship. The relationship of the precipitation and temperature trends with water vapor and relative humidity was either positive or negative. The most significant controlling factor for the climate variables was relative humidity, which was governed by water vapor pressure in the study area. Further investigations are needed to better understand the climatic influences in other complex physiographic landscapes, and to determine reliable mechanisms to more effectively integrate water cycle variables, high resolution data, and climatic modeling.
Study on the Decoupling Effects of Carbon Emission in Shandong Tourism
Tian, Hong,Sun, Fengzhi,Ding, Changan 한중경제문화학회 2015 한중경제문화연구 Vol.5 No.-
With the depth research in global climate change and the rapid development of tourism industry, tourism industry has been paid more and more attention to carbon emissions. Shandong Province is a major tourism province, the tourism industry not only has the high speed development, but also has expanded each year, the issue of tourism carbon emissions has become one of the important problems to be solved. By using Tapio model to analyze the decoupling relationship between economic growth and carbon emissions in Shandong Province tourism during 2000-2013, and decomposed the total decoupling indicator into the energy saving decoupling indicator and emission reduction decoupling indicator to study, the results showed that: the decoupling relationship between economic growth and carbon emissions in Shandong Province tourism was mainly weak decoupling, energy saving decoupling indicator was the main influence factor of the total decoupling indicators being weak decoupling state, emissions reduction decoupling indicator showed a weak influence on the total decoupling indicators being weak decoupling state. When Shandong Province develop the low-carbon tourism, efforts should be made to create a good institutional environment, to increase research and development of low carbon technology, to improve the level of low-carbon tourism facilities, to optimize energy consumption structure, to increase the proportion of the use of low carbon energy.
Analysis of Rural Tourism Service Quality and improvement Countermeasures of Shandong Province
Xu, Jia,Sun, Fengzhi 한중경제문화학회 2015 한중경제문화연구 Vol.4 No.-
Tourism service quality is the lifeline for the survival of tourism enterprises , which is the core embodiment of the competitiveness of tourism enterprises. Based on the perspective of tourists perceived value, this paper aimed to analyze the quality of rural tourism of Shandong province, it indentified the effect factors of tourist service quality from two research perspective: the impact to the expectations before the tourists travel process and the experience during tourists travel the process. And then, through the analysis of problems existing in the rural tourism service of Shandong province, it put forward the relative countermeasures. Key Words
Rotational behavior of exposed column bases with different base plate thickness
Yao Cui,Fengzhi Wang,Hao Li,Satoshi Yamada 국제구조공학회 2019 Steel and Composite Structures, An International J Vol.32 No.4
Exposed column base connections are used in low- to mid-rise steel moment resisting frames. This paper is to investigate the effect of the base plate thickness on the exposed column base connection strength, stiffness, and energy dissipation. Five specimens with different base plate thickness were numerically modelled using ABAQUS software. The numerical model is able to reproduce the key characteristics of the experimental response. Based on the numerical analysis, the critical base plate thickness to identify the base plate and anchor rod yield mechanism is proposed. For the connection with base plate yield mechanism, the resisting moment is carried by the flexural bending of the base plate. Yield lines in the base plate on the tension side and compression side are illustrated, respectively. This type of connection exhibits a relatively large energy dissipation. For the connection with anchor rod yield mechanism, the moment is resisted through a combination of bearing stresses of concrete foundation on the compression side and tensile forces in the anchor rods on the tension side. This type of connection exhibits self-centering behavior and shows higher initial stiffness and bending strength. In addition, the methods to predict the moment resistance of the connection with different yield mechanisms are presented. And the evaluated moment resistances agree well with the values obtained from the FEM model.
Analysis of Rural Tourism Service Quality and improvement Countermeasures of Shandong Province
Xu, Jia,Sun, Fengzhi 한중경제문화학회 2015 한중경제문화연구 Vol.4 No.-
Tourism service quality is the lifeline for the survival of tourism enterprises , which is the core embodiment of the competitiveness of tourism enterprises. Based on the perspective of tourists perceived value, this paper aimed to analyze the quality of rural tourism of Shandong province, it indentified the effect factors of tourist service quality from two research perspective: the impact to the expectations before the tourists travel process and the experience during tourists travel the process. And then, through the analysis of problems existing in the rural tourism service of Shandong province, it put forward the relative countermeasures.
Zhibo Zhang,Huifang Huang,Fengzhi Feng,Jinhui Wang,Ninghai Cheng 대한부인종양학회 2019 Journal of Gynecologic Oncology Vol.30 No.4
Objective: This study aims to evaluate the effects and pregnancy outcomes of gonadotropin-releasing hormone agonist (GnRH agonist) combined with aromatase inhibitor (AI) in preserving the fertility of obese women with grade 1 endometrial cancer (EC). Methods: This study recruited obese EC patients who wished to preserve their fertility. The treatment regimen consisted of intramuscular GnRH agonist 3.75 mg every 4 weeks and oral AI 2.5 mg daily. The maintenance regimen was the same as the initial treatment regimen. Primary outcomes included response rate, time to complete response (CR), and time to recurrence; pregnancy outcomes included the time to pregnancy, pregnancy rate and live birth rate. Results: Six obese patients with EC were included in this study, with the age (mean±standard deviation [SD]) of 30.5±3.3 years and body mass index (mean±SD) of 35.0±1.4 kg/m2. CR rate was 100%, and time to CR was 3–6 months. None of the patients had recurrence after a median follow-up of 4.0 years (range, 1.3–7.0 years). The most common side effects were menopause-like symptoms. Among these patients, no weight gain was observed during treatment. The pregnancy rate and live birth rate was 50.0% and 75.0%, respectively, with a median time to pregnancy of 2.4 years (range, 1.0–5.5 years). Conclusion: The combination of GnRH agonist and AI demonstrated promising long-term effect in young obese EC patients who wished to preserve their fertility. No weight gain side effects were observed. Further studies with a larger sample size are needed to fully evaluate this novel treatment regimen.