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      • KCI등재

        Multibiometrics fusion using Aczel-Alsina triangular norm

        ( Ning Wang ),( Li Lu ),( Ge Gao ),( Fanglin Wang ),( Shi Li ) 한국인터넷정보학회 2014 KSII Transactions on Internet and Information Syst Vol.8 No.7

        Fusing the scores of multibiometrics is a very promising approach to improve the overall system`s accuracy and the verification performance. In recent years, there are several approaches towards studying score level fusion of several biometric systems. However, most of them does not consider the genuine and imposter score distributions and result in a higher equal error rate usually. In this paper, a novel score level fusion approach of different biometric systems (dual iris, thermal and visible face traits) based on Aczel-Alsina triangular norm is proposed. It achieves higher identification performance as well as acquires a closer genuine distance and larger imposter distance. The experimental tests are conducted on a virtual multibiometrics database, which merges the challenging CASIA-Iris-Thousand database with noisy samples and the NVIE face database with visible and thermal face images. The rigorous results suggest that significant performance improvement can be achieved after the implementation of multibiometrics. The comparative experiments also ascertain that the proposed fusion approach outperforms the state-of-art verification performance.

      • KCI등재후보

        DDAB-MODIFIED TPGS-b-(PCL-ran-PGA) NANOPARTICLES AS ORAL ANTICANCER DRUG CARRIER FOR LUNG CANCER CHEMOTHERAPY

        TIEJUN ZHAO,HEZHONG CHEN,LIXIN YANG,HAI JIN,ZHIGANG LI,LIN HAN,FANGLIN LU,ZHIYUN XU 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2013 NANO Vol.8 No.2

        Oral chemotherapy is a great way to cancer treatment because it is less stressful being that the patient will have less hospital visits and can still maintain a close relationship with health care professionals. In this research, three types of nanoparticle formulation from commercial PCL and self-synthesized TPGS-b-(PCL-ran-PGA) diblock copolymer were fabricated for oral delivery of antitumor agents, including DDAB-modified PCL nanoparticles, unmodified TPGS-b-(PCL-ran-PGA) nanoparticles and DDAB-modified TPGS-b-(PCL-ran-PGA) nanoparticles. Firstly, the TPGS-b-(PCL-ran-PGA) diblock copolymer was synthesized and characterized. DDAB was adopted to increase retention time at the cell surface, thus increasing the chances of nanoparticle uptake by the gastrointestinal mucosa and improving drug absorption. The TPGS-b-(PCL-ran-PGA) nanoparticles were found by FESEM of spherical shape and around 200 nm in diameter. The surface charge of TPGS-b-(PCL-ran-PGA) nanoparticles was reversed from anionic to cationic after DDAB modification. The DDAB-modified TPGS-b-(PCL-ran-PGA) nanoparticles have significantly higher level of the cell uptake than that of DDAB-modified PCL nanoparticles and unmodified TPGS-b-(PCL-ran-PGA) nanoparticles. In vitro cell viability studies showed advantages of the DDAB-modified TPGS-b-(PCL-ran-PGA) nanoparticles over Taxotere® in terms of cytotoxicity against A549 cells. In conclusion, oral chemotherapy by DDAB-modified TPGS-b-(PCL-ran-PGA) nanoparticle formulation may provide a promising outcome for lung cancer patients.

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