Nurses’ attitudes and stress related to perinatal bereavement care in Korea: a cross-sectional survey

( Eunhui Kim ),( Hae Won Kim ) 한국여성건강간호학회 2022 여성건강간호학회지 Vol.28 No.2

Purpose: A descriptive correlational survey was conducted to examine nurses’ attitudes and stress related to perinatal bereavement care (PBC) and their relationships, with the ultimate goal of improving nurses’ capabilities related to PBC. Methods: Korean nurses (N=136) who had experienced perinatal death at least once were recruited from seven hospitals. Data were analyzed using descriptive statistics. The Korean version of Nurses’ Attitudes towards Perinatal Bereavement Support was assessed in terms of three subdomains (attitudes to PBC, importance of policies related to PBC, and importance of training related to PBC), and nurses’ stress was measured. Results: The participants gave high scores for the attitude-related items of “giving sufficient time to bereaved parents to mourn for their dead baby” (4.54 points) and “nurses should treat bereaved parents with respect and dignity” (4.51 points), and they perceived a high level of importance for the policy-related items of “every staff member in the hospital should understand the policies relevant for PBC” and “when nurses feel emotional exhaustion, they should seek support” (4.58 points). Nurses’ attitude toward PBC was associated with the perceived importance of policies (r=.40, p<.001), the perceived importance of PBC-related training (r=.61, p<.001), and stress related to PBC (r=.29, p<.001). Nurses’ perceived importance of PBC-related training was associated with stress related to PBC (r=.38, p<.001). Conclusion: Establishing hospital policies related to PBC and providing PBC training for nurses could positively affect nurses’ attitudes toward PBC. A stress management program for nurses could reduce the stress caused by PBC.

Alteration of Lipid Metabolism Related Proteins in Liver of High-Fat Fed Obese Mice

Eunhui Seo(서은희),Ying Han(한영),So-Young Park(박소영),Hyongjong Koh(고형종),Hye-Jeong Lee(이혜정) 한국생명과학회 2010 생명과학회지 Vol.20 No.7

과체중과 비만은 당뇨병, 고혈압, 고지혈증과 같은 신진 대사 질환의 발병과 강력하게 연관되어 있다. 비만의 원인은 여러가지가 있겠지만, 고지방식이는 비만의 원인 중 가장 중요한 요소 중 하나이다. 본 연구에서는 C57BL/6 생쥐에게 22주간의 고지방 식이를 주었으며, 이를 통해 비만과 고혈당을 유도하였다. 22주 후에 고지방식이를 한 생쥐들에서 체중과 혈장 포도당 수준이 정상 식이를 한 생쥐들에 비해 크게 증가함을 관찰하였다. 복막 내 당 부하 검사(IPGTT)에서도 고지방 식이를 한 생쥐들은 정상 식이를 한 생쥐들에 비해서 당 내성 이상 반응을 보여주었다. 이러한 결과들은 고지방식이가 C57BL/6 생쥐에서 비만 및 고혈당을 유도한다는 사실을 확인시켜 주었다. 고지방식이군 생쥐들에서는 정상식이군의 생쥐들에 비해 혈장의 중성지방과 총 콜레스테롤의 양이 증가됨이 관찰되었다. 간에서의 중성지방 및 총 콜레스테롤의 수준도 역시 증가하였다. 따라서, 간에서의 지질 대사가 어떻게 변하였는지를 알기 위해, 지질대사에 관련된 단백질들의 변화를 관찰하였다. 지방 합성과 관련된 효소들 중 FAS와 GPAT가 고지방식이 군에서 의미있게 증가 되어있었으며, 지방 수송에 관련하는 단백질 중에서도 ApoB 및 MTP의 큰 증가가 고지방식이군에서 관찰되었다. 흥미롭게도, 대사 조절 인자로 알려진 AMPK의 단백질의 양과 인산화 정도는 정상식이군에 비해 고지방식이군에서 의미있게 증가되었음이 관찰되었다. 결론적으로, 본 연구에서 우리는 고지방식이가 지질 합성과 지질 수송과정을 생리학적으로 증가시키지만, 역설적으로 AMPK의 활성화를 유발한다는 것을 확인하였다. Obesity and being overweight are strongly associated with the development of metabolic disease such as diabetes, hypertension, dyslipidemia. High-fat diet (HFD) is one of the most important factors which cause obesity. In this study, C57BL/6 mice were treated with a HFD for 22 weeks in order to induce obesity and hyperglycemia. Twenty-two weeks later, body weight and plasma glucose level of the HFD group were significantly increased, compared with the normal diet (ND) group. Intra-peritoneal glucose tolerance test (IPGTT) showed glucose intolerance in the HFD group compared with the ND group. These results confirmed that a HFD induced obesity and hyperglycemia in C57BL/6 mice. Plasma levels of triglyceride (TG) and total cholesterol (TC) were increased in the HFD group compared with the ND group. Hepatic levels of TG and TC were also increased by a HFD. To investigate the alteration of lipid metabolism in liver, proteins which are related to lipid metabolism were observed. Among lipid synthesis related enzymes, fatty acid synthase (FAS) and glycerol phosphate acyl transferase (GPAT) were significantly increased in the HFD group. Apolipoprotein B (apoB) and microsomal triglyceride transport protein (MTP), which are related to lipid transport, were significantly increased in the HFD group. Interestingly, protein level and phosphorylation of AMP-activated protein kinase (AMPK), which is known as a metabolic regulator, were significantly increased in the HFD group compared with the ND group. In the present study we suggest that HFD may physiologically increase the proteins which are related with lipid synthesis and lipid transport, but that HFD may paradoxically induce the activation of AMPK.

Overexpression of AMPKՁ1 Ameliorates Fatty Liver in Hyperlipidemic Diabetic Rats

Eunhui Seo,Eun-Jin Park,Yeonsoo Joe,Soojeong Kang,Mi-Sun Kim,Sook-Hee Hong,Mi-Kyoung Park,Duk Kyu Kim,Hyongjong Koh,Hye-Jeong Lee 대한생리학회-대한약리학회 2009 The Korean Journal of Physiology & Pharmacology Vol.13 No.6

5 -AMP-activated protein kinase (AMPK) is a heterotrimeric complex consisting of a catalytic (Ձ) and two regulatory (Ղ and Ճ) subunits. Two isoforms are known for catalytic subunit (Ձ1, Ձ2) and are encoded by different genes. To assess the metabolic effects of AMPKՁ1, we examined the effects of overexpression of adenoviral-mediated AMPKՁ1 in hyperlipidemic type 2 diabetic rats. The Otsuka Long-Evans Tokushima Fatty (OLETF) rat is an established animal model of type 2 diabetes that exhibits chronic and slowly progressive hyperglycemia and hyperlipidemia. Thirty five-week-old overt type 2 diabetic rats (n=10) were administered intravenously with Ad.AMPKՁ1. AMPK activity was measured by phosphorylation of acetyl CoA carboxlyase (ACC). To investigate the changes of gene expression related glucose and lipid metabolism, quantitative real-time PCR was performed with liver tissues. Overexpression of AMPKՁ1 showed that blood glucose concentration was decreased but that glucose tolerance was not completely recovered on 7th day after treatment. Plasma triglyceride concentration was decreased slightly, and hepatic triglyceride content was markedly reduced by decreasing expression of hepatic lipogenic genes. Overexpression of AMPKՁ1 markedly improved hepatic steatosis and it may have effective role for improving hepatic lipid metabolism in hyperlipidemic state.

Establishment of genetically engineered zebra finch chondrocyte-like cell line by c-MYC expression

Eunhui Yoo,Kyung Min Jung,Young Min Kim,Jae Yong Han 한국가금학회 2022 한국가금학회 정기총회 및 학술발표회 Vol.2022 No.11

A Study on Comparative Exploration of Optimizer Techniques for fine-tuning of language models

Eunhui Kim,Youna Jung,Minho Lee,WonKyung Sung 한국콘텐츠학회 2021 한국콘텐츠학회 ICCC 논문집 Vol.2021 No.12

Melittin Induces Apoptosis in Non-Small Cell Lung Cancer and Increase Radiosensitivity

Eunhui Seo,Kyung-Ok Kim,Kyeongah Kim,Yunsook Choi,Kyu Chan Lee 대한방사선방어학회 2023 대한방사선방어학회 학술발표회 논문요약집 Vol.2023 No.4

An Automatic Recommendation Scheme of TV Program Contents for (IP)TV Personalization

Eunhui Kim,Shinjee Pyo,Eunkyung Park,Munchurl Kim IEEE 2011 IEEE transactions on broadcasting Vol.57 No.3

<P>Due to the rapid increase of contents available under the convergence of broadcasting and Internet, efficient access to personally preferred contents has become an important issue. In this paper, an automatic recommendation scheme based on collaborative filtering is presented for intelligent personalization of (IP)TV services. The proposed scheme does not require TV viewers (users) to make explicit ratings on their watched TV program contents. Instead, it implicitly infers the users' interests on the watched TV program contents. For the recommendation of user preferred TV program contents, our proposed recommendation scheme first clusters TV users into similar groups based on their preferences on the content genres from the user's watching history of TV program contents. For the personalized recommendation of TV program contents to an active user, a candidate set of preferred TV program contents is obtained via collaborative filtering for the group to which the active user belongs. The candidate TV programs for recommendation are then ranked by a proposed novel ranking model. Finally, a set of top- <I>N</I> ranked TV program contents is recommended to the active user. The experimental results show that the proposed TV program recommendation scheme yields about 77% of average precision accuracy and 0.135 value of <I>ANMRR</I> (Average Normalized Modified Retrieval Rank) with top five recommendations for 1,509 people.</P>

They Are Not Machines: Korean Women Workers and Their Fight for Democratic Trade Unionism in the 1970s, by Soonok Chun, Cornwall

Eunhui Eom 부산대학교 한국민족문화연구소 2011 Localities Vol.1 No.-

[Book Reviews]They Are Not Machines: Korean Women Workers and Their Fight for Democratic Trade Unionism in the 1970s

Eunhui Eom 부산대학교 한국민족문화연구소 2011 Localities Vol.- No.1

Differential Expression of Metabolism-related Genes in Liver of Diabetic Obese Rats

Eunhui Seo,Eun-Jin Park,Mi-Kyoung Park,Duk Kyu Kim,Hye-Jeong Lee,Sook-Hee Hong 대한생리학회-대한약리학회 2010 The Korean Journal of Physiology & Pharmacology Vol.14 No.2

The Otsuka Long-Evans Tokushima Fatty (OLETF) rat, a model of spontaneous type 2 diabetes (T2D), develops hyperglycemic obesity with hyperinsulinemia and insulin resistance after the age of 25 weeks, similar to patients with noninsulin-dependent diabetes mellitus (DM). In the present study, we determined whether there are differences in the pattern of gene expression related to glucose and lipid metabolism between OLETF rats and their control counterparts, Long-Evans Tokushima (LETO) rats. The experiment was done using 35-week-old OLETF and LETO rats. At week 35 male OLETF rats showed overt T2D and increases in blood glucose, plasma insulin, plasma triglycerides (TG) and plasma total cholesterol (TC). Livers of diabetic OLETF and LETO rats also showed differences in expression of mRNA for glucose and lipid metabolism related genes. Among glucose metabolism related genes, GAPDH mRNA was significantly higher and FBPase and G6Pase mRNA were significantly lower in OLETF rats. For lipid metabolism related genes, HMGCR, SCD1 and HL mRNA were substantially higher in OLETF rats. These results indicate that gluconeogenesis in OLETF rats is lower and glycolysis is higher, which means that glucose metabolism might be compensated for by a lowering of the blood glucose level. However, lipid synthesis is increased in OLETF rats so diabetes may be aggravated. These differences between OLETF and LETO rats suggest mechanisms that could be targeted during the development of therapeutic agents for diabetes.