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Isolation and characterization of Mesenchymal stem cell derived from umbilical cord blood
Shin, Eulsoon,Yang, Keum-Jin,Piao, Longzhen,Shin, Sanghee,Li, Yuwen,Kim, Young-Rae,Byun, Hee Sun,Won, Minho,Park, Kyung Ah,Lee, Hyunji,Hur, Gangmin,Seok, Jeong Ho,Kim, Jeong-Lan,Kwon, Gye-Cheol,Park, 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10
Melittin, a Amphipathic Cationic Peptide that Causes ROS-Mediated Apoptosis in Prostate Cancer Cell
Shin, Eulsoon,Yang, Keum-Jin,Piao, Longzhen,Shin, Sanghee,Li, Yuwen,Kim, Young-Rae,Byun, Hee Sun,Won, Minho,Park, Kyung Ah,Lee, Hyunji,Choi, Byung Lyul,Hong, Jang Hee,Hur, Gangmin,Seok, Jeong Ho,Park, 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10
Effects of Melittin on Oxidative Stress Mediated Induction of Apoptosis in Prostate Cancer Cell
Shin, Eulsoon,Yang, Keum Jin,Piao, Longzhen,Shin, Sanghee,Li, Yuwen,Kim, Young-Rae,Byun, Hee Sun,Won, Minho,Park, Kyung Ah,Lee, Hyunji,Choi, Byung Lyul,Hong, Jang Hee,Hur, Gangmin,Seok, Jeong Ho,Park, 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10
Differentiation potential of Mesenchymal stem cell derived from Bone Marrow
Li, Yuwen,Shin, Eulsoon,Yang, Keum-Jin,Piao, Longzhen,Shin, Sanghee,Kim, Young-Rae,Byun, Hee Sun,Won, Minho,Park, Kyung Ah,Lee, Hyunji,Hur, Gangmin,Seok, Jeong Ho,Kim, Jeong-Lan,Kwon, Gye-Cheol,Park, 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10
영어 의사소통 능력 향상을 위한 비폭력대화 활용 초등 영어 프로그램 개발
박선영(Seonyoung Park),이을순(Eulsoon Lee) 학습자중심교과교육학회 2022 학습자중심교과교육연구 Vol.22 No.22
목적 본 연구의 목적은 영어 의사소통 능력 향상을 위하여 비폭력대화를 활용한 초등 영어 프로그램을 개발하는 것이다. 방법 이를 위하여 ADDIE 모형의 절차인 분석, 설계, 개발, 실행, 평가 단계에 따라 프로그램을 개발하였다. 자문단의 협의를 거친 후, 초등학교 6학년 23명을 대상으로 프로그램을 적용하여 최종 수정 보완하였다. 결과 연구 결과는 다음과 같다. 첫째, 영어과 교육과정과 의사소통 기능 분석을 통해 비폭력대화를 활용한 영어 수업의 가능성을 확인한 후, 비폭력대화의 네 가지 단계인 관찰, 느낌, 욕구, 부탁에 기초하여 영어 의사소통 능력 향상을 위한 프로그램을 구안하였다. 둘째, 프로그램의 구체적인 적용사례로서 교수⋅학습지도안을 개발하여 제시하였으며 적용 사례를 분석하여 프로그램 적용의 시사점을 도출하였다. 결론 비폭력대화를 활용한 초등 영어 프로그램을 통하여 실제적인 의사소통의 폭을 넓히고 영어과 목표 및 세계 시민으로서의 교과역량과 핵심역량 함양을 도모할 수 있다는 점에서 의의가 있다. 영어교육의 관점에서 비폭력대화를 활용한 후속 연구가 필요함을 제안한다. Objectives The purpose of this study was to develop an English program based on nonviolent communication to improve students’ English communicative competence. Methods This program was developed based on the ADDIE model, which consists of analysis, design, development, implementation, and evaluation stage. After being examined by an expert group, this program was conducted with 23 elementary school students. Results The study found that nonviolent communication relating to communicative competence could be associated with the 2015 revised curriculum. Secondly, according to the four components of nonviolent communication, communicative functions were categorized and the English program was designed in a way that nonviolent communication could be applied and practiced. Lastly, an example lesson plan was created and provided as guidance and executed in the classroom. Conclusions Based on the results, it was discovered that there is a possibility to adapt nonviolent communication to improve students’ communicative competence. Also, this study implied that this English program based on nonviolent communication could expand the scope of genuine communication. Further studies on nonviolent communication are required for English education.
Protective effects of compound B1 on liver injury in alcohol-fed rats
Shin, Sanghee,Yang, Keum-Jin,Piao, Longzhen,Shin, Eulsoon,Li, Yuwen,Park, Kyeong Ah,Byun, Hee Sun,Won, Minho,Kim, Young-Rae,Lee, Hyunji,Hur, Gang Min,Seok, Jeong Ho,Kim, Jin Man,Song Minho,Park, Jongs 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10
Yang, Keum-Jin,Shin, Sanghee,Piao, Longzhen,Shin, Eulsoon,Li, Yuwen,Park, Kyeong Ah,Byun, Hee Sun,Won, Minho,Hong, Janghee,Kweon, Gi Ryang,Hur, Gang Min,Seok, Jeong Ho,Chun, Taehoon,Brazil, Derek P,He American Society for Biochemistry and Molecular Bi 2008 The Journal of biological chemistry Vol.283 No.3
<P>3-Phosphoinositide-dependent protein kinase-1 (PDK1) appears to play a central regulatory role in many cell signalings between phosphoinositide-3 kinase and various intracellular serine/threonine kinases. In resting cells, PDK1 is known to be constitutively active and is further activated by tyrosine phosphorylation (Tyr(9) and Tyr(373/376)) following the treatment of the cell with insulin or pervanadate. However, little is known about the mechanisms for this additional activation of PDK1. Here, we report that the SH2 domain of Src, Crk, and GAP recognized tyrosine-phosphorylated PDK1 in vitro. Destabilization of PDK1 induced by geldanamycin (a Hsp90 inhibitor) was partially blocked in HEK 293 cells expressing PDK1-Y9F. Co-expression of Hsp90 enhanced PDK1-Src complex formation and led to further increased PDK1 activity toward PKB and SGK. Immunohistochemical analysis with anti-phospho-Tyr(9) antibodies showed that the level of Tyr(9) phosphorylation was markedly increased in tumor samples compared with normal. Taken together, these data suggest that phosphorylation of PDK1 on Tyr(9), distinct from Tyr(373/376), is important for PDK1/Src complex formation, leading to PDK1 activation. Furthermore, Tyr(9) phosphorylation is critical for the stabilization of both PDK1 and the PDK1/Src complex via Hsp90-mediated protection of PDK1 degradation.</P>