보건소를 이용하는 지역주민의 건강 행위와 건강관련 체력간의 관계

전미양,최명애,이인숙,김태수,김의숙,박선홍 대한보건협회 2002 대한보건연구 Vol.28 No.3

The purpose of this study is to identify relationship health behavior and health related physical fitness in order to provide the basic data for health promotion program for community people. The study was conducted 299 people, during the period from June 1, 2000 to October 30, 2000. The result are as follows. 1. Female comprised was 63.2%(189), while male comprised 36.8%(110). The age range of the subject were from 21 to 59 years old. The subject were aged 30s group 52.5%, 40s group 29.1%, 50s group 12.7%, 20s group 5.7%. Twenty subjects (6.7%) had experience smoking and one subject (0.3%) in female and nineteen subjects (6.4%) in male. Seventy-five subjects (25.1%) had experience drinking and twenty-nine subjects (9.7%) in female, and forty-six (15.4%) in male subjects. ninety-nine subjects had exercise and sixty subjects (20.1%) in female subjects and thirty-mine subject (13%) in male. 2. Body fat and flexibility were higher in female than male subjects, but cardioresperatory endurance, muscular strength and muscular endurance were higher in male than female subjects. 3. There were significant differences in body fat and muscular endurance between age group in both gender subjects, and in cardioresperatory endurance and muscular strength between the age group in male subjects. 4. No significant differences health related fitness between non-smoking and smoking group in both gender subjects. 5. No significant differences health related fitness between non-alcohol and alcohol group in both gender subjects. 6. For female subjects, muscular strength, muscular endurance and flexibility of the exercise group were significantly higher than those of the non exercise group. for male subjects, cardiorespiratory endurance of the exercise group were significantly higher than those of the non exercise group.

대장선암에서 p53 과 P-glycoprotein의 분포에 관한 연구

강상균,김의한,장인성,김대중,양승하 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.1

Adenocarcinoma of colon and rectum express many oncogenes. The p53 acts as tumor suppressor in normal tissue but mutant forms are known as doing important role in carcinogenesis of many malignant tumors, such as colorectal cancer, gastric cancer, and breast cancer. P-glycoprotein shows distribution in many normal tissues and malignant tumor. This protein occurs multidrug resistance to therapeutic anticancer drug, resulting in poor prognosis of patients. The expression of p53 and P-glycoprotein has been studied by many authors according to clinicopthologic findings of colorectal adenocarcinoma, but these results are controversial yet. To observe the relationship between both antigen and pathologic findings, including prognostic factos, of colorectal adenocarcinoma, we analysed 13 cases adenoma and 62 cases adenocarcinoma then processed for immunohistochemical stain by SLAB method using mouse monoclonal anti-p53 and JSB-1. The results were as followings; 1) The expression rate of p53 in adenoma and adenocarcinoma are 38.5% and 71.0%, respectively, and P-glycoprotein are 46.6% and 58.1%, respectively. 2) The p53 revealed higher expression rate in case of well differnetiated form, invasion to serosa and surrounding adipose tissue, lymphatic metastasis compared to that of moderately and poorly differentiated form, invasion to muscle, no lymphatic metastasis, but no difference accoding to site. 3) P-glycoprotein revealed higher positive rate in case of right side, invasion to surrounding adipose tissue, lymphatic metastasis compared to that of left side, invasion to muscle and serosa, no lymphatic metastasis, but no difference according to differentiation. 4) Both of p53 and P-glycoprotein revealed higher ex pression in case of right side, well and moderately differentiated form, invation to serosa and surrounding adipose tissue, lymphatic metastasis compared to that of left side, poorly differentiated form, invasion to muscle, no lymphatic metastasis. Above results revealed that the expression of p53 begins in adenoma and shows close relation with development of colorectal carcinoma. p53 and P-glycoprotein may reveal the relation with poor prognosis. Adenocarcinoma showing both positive reaction of p53 and P-glycoprotein is also similar prognostic relation.

How Textual Sources Affect Fashion Design Ideation and Developing Process

( Eui Young Yang ),( Hoe Ryung Lee ),( Su Jin Park ),( Ji Woon Jeong ),( Hye In Park ),( Jisoo Ha ) 한국의류산업학회 2021 한국의류산업학회지 Vol.23 No.1

The research expects that textual sources such as reading texts with additional information in the form of texts can be effective inspiration sources for fashion design ideation and development process. This research analyzes how efficiently textual sources work along with individual internal sources, such as sociocultural influence, design fixation, and during the design process. Six fashion design graduate students shared 2 inspirational experiences under 2 different studies (4 experiences in total); in addition, in-depth interviews were conducted based on individual design sketches. The result shows that textual sources provided a positive effect on all 6 participants with different intensities based on various backgrounds and individual tastes. This result demonstrates individual ‘influence’ (their sociocultural capital such as personal preferences, likings, habits, and past experiences) and ‘inspiration’ mutually work together to make an effect on fashion designers’ ideation and development process for the design, sometimes one working more than the other (or vice versa), respectively. This paper makes important practical contributions by identifying and discussing the design behavior performed (especially in fashion design) by fashion design students during the design process with new sources of inspiration provided such as textual sources. The research revealed how textual sources can be an effective inspiration for fashion design students and provide insight to fashion design educators and professional fashion designers.

INS-1 세포에서 SHP에 의해 유도된 유전자발현의 변화에 대한 마이크로어레이 분석

정의달 ( Eui Dal Jung ),이지현 ( Ji Hyun Lee ),장원구 ( Won Gu Jang ),김정국 ( Jung Guk Kim ),김보완 ( Bo Wan Kim ),이인규 ( In Kyu Lee ) 대한당뇨병학회 2007 Diabetes and Metabolism Journal Vol.31 No.3

DTC를 이용한 새로운 파라메터 추출법

서용진,신희갑,이철인,장의구 중앙대학교 기술과학연구소 1994 기술과학연구소 논문집 Vol.24 No.-

In the manufacturing of VLSI circuits, variations of device characteristics due to the slight differences in process parameters drastically aggravate the performances of fabricated devices. Therefore, it is very important to establish optimal process conditions in order to minimize device sensitivities. In this paper, we used one-dimensional process simulator, SUPREM-Ⅱ, and two-dimensional device simulator, MINIMOS 4.0 in order to extract optimal process parameter which can minimize changes of the device characteristics caused by process parameter variation in the case of short channel nMOSFET and pMOSFET device. From this simulation, we have derived the dependence relationship between process parameters and device characteristics. Here, we have presented a method to extract process parameters from design trend curve(DTC)obtained by process and device simulations.

정상 한국인 성인 남녀에서 협골을 중심으로 한 중안모의 측모 두부방사선 규격사진 분석법

정인교,이의훈 大韓顎顔面成形再建外科學會 1999 Maxillofacial Plastic Reconstructive Surgery Vol.21 No.4

Purpose : A new method of lateral cephalometric analy sis for midface, focusing on zygomatic bone, was created in this study, and measured in Korean adults. The purposes of this study are understanding about new approach for midfacial depression, especially zygomatic bone, and using to make adequate diagnosis and treatment plan. Materials and methods : In this study, esthetic Korean adults, 25 males and 25 females who were between 0˚and 4˚in ∠ANB, and between 62% and 70% in P/A facial height ratio, and had normal overbite and overjet, were used. Orbitale(Or) and Soft tissue orbitale(Or') were used for indicators of anteroposterior position of zygomatic area. And, mean value and standard deviation of linear and angular meansurements, and ratio about each linear measurements, were obtained. then, standard deviation diagram - wiggle diagram- was made for visualization of results. Results : Mean values, standard deviations and ranges of 19 meansurements were obtained, and among them, 5 linear meansurements that had large standard deviation were excluded and the others were used for making standard deviation diagram. In standard deviation diagram, the following results were obtained. 1. If the measurements are located on more left side of mean-value- vertical-line, the potential of midfacial hypoplasia are stronger, especially zygomatic area. 2. If the measurements are located on more right side ofmean-value-vertical-line, the potential of midfacial hypoplasia are decreased. Conclusion : This study presented a new method of lateral cephalometric analysis focusing on zygomatic bone in Korean adults. We expect that the results of this study can be used as parameter when clinicians make decisions about diagnosis and treatment plan for rehabilitation of esthetics and function. But, it is necessary to prove its usefulness, and to further evaluate the results.

유산소운동이 정신장애인의 신체조성, 체력, 폐활량에 미치는 영향

이석인,이의수 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

The purpose of this study is to find out what effects aerobic exercise has on the body formation and physical strength of people suffering from schizophrenia, [n order to do so, we conducted an experiment, in which we selected seven men and seven women from the thirties to sixties who were diagnosed with schizophrenia by their physicians in S mental hospital in Seoul, Afterward, we had those people do aerobic exercise and analyzed the change in body formation, physical strength, and breathing capacity, Followings are the result of our experiment. 1. Although there was a slight decline in Body Mass Index (BMI) of both the group of men and women, it was not a significant difference statistically. On the other hand, there was a statistically significant change in the density of body and the account of body fat of both the group of men and women(p<.05). 2. There was a slight increase in abdominal muscle power of both the group of men and women, which was not a statistically significant difference. As for Trunk Flexion that indicates flexibility, the group of women showed a significant increase (p<.05), whereas the group of men did not show a significant difference, although there was a slight increase, Concerning Whole Body Response that indicates agility, both men and women showed a significant increase(p<.05). 3. Considering Functional Vital Capacity (FVC), while the group of women showed a significant increase (p<.05), the group of mere did not show a statistically significant difference despite a slight increase, There was a significant increase in %FVC of both men and women (p<.05), and regarding Forced Expiratory Volume (FEV1.0), there was a slight increase of both the group of men and women, which was statistically not a significant change.

광범위 베타 락탐계 항생제 분해 효소를 생성하는 폐렴간균에 의한 균혈증이 발생한 환자에서 감영의 위험 인자 및 치료 결과

강철인,김성한,방지환,김홍빈,박상원,최영주,오명돈,김의종,최강원 대한감염학회 2003 감염과 화학요법 Vol.35 No.2

목적 : 본 연구는 ESBL을 생성하는 K. pneumoniae에 의한 균혈증 환자에서 감염의 위험 인자 및 치료 결과를 알아보고자 시행하였다. 방법 : 1998년 1월부터 2002년 4월까지 혈액 배양 검사에서 동정된 K. pneumoniae를 대상으로 NCCLS guidelines과 이중 디스크 확산법(double-disk diffusion test)을 이용하여 ESBL 생성 여부를 확인하였다. ESBL 생성 균주에 의한 균혈증 환자 60명(환자군)에 대해 ESBL을 생성하지 않는 균주에 의한 균혈증 환자들(대조군)을 연령, 성별, 균혈증 발생 시점을 고려하여 1:2 또는 1:3으로 배정하였다. 총 159명의 대조군을 선정하였고 후향적인 환자-대조군 연구를 시행하였다. 결과 : 환자군과 대조군 사이에 연령, 성별, APACHE Ⅱ score, 주된 감염 부위의 유의한 차이는 없었다. ESBL을 생성하는 K. pneumoniae에 의한 균혈증이 발생할 독립적인 위험 인자에는 요관 삽입, 균혈증 발생 이전 72시간 동안 침습적인 시술을 받은 경우, 균혈증 발생 이전 30일 동안 투여받은 항생제 개수가 있었다. 초기 항생제 치료 72시간 후의 반응을 평가하였을 때, 완전 반응(complete response)은 대조군에서 더 많았고(13.3% vs. 40.3%, P<0.001), 치료 실패(treatment failure)는 환자군에서 더 많았다(33.3% vs. 11.9%, P<0.001). 7일 사망률은 환자군에서 20% (12/60), 대조군에서 15.6% (25/159)이었고(P=0.451), 30일 사망률은 환자군에서 30% (18/60), 대조군에서 24.5% (39/159)이었다(P=0.410). ESBL 생성 균주에 의한 균혈증이 있는 환자들에서 최종 항생제 치료가 부적절했던 환자들을 제외하고 30일 사망률을 분석하였을 때 효과적인 항생제 치료의 지연은 사망률을 높이지 않았다(11.1% vs. 9.1%, P=1.000). 결론 : ESBL을 생성하는 K. pneumoniae에 의한 균혈증이 있는 환자에서 초기 항균제 치료 72시간 후의 치료 반응률은 낮지만 사망률은 유의하게 증가하지 않았다. 원인균이 동정된 후 최종 치료 항생제의 선정이 적절하다면 초기에 효과적인 항생제 투여의 지연은 사망률을 유의하게 증가시키지는 않았다. Background : This study was conducted to evaluate risk factors for infection and treatment outcome of bloodstream infection due to extended spectrum β-lactamases(ESBL)-producing K. pneumoniae. Methods: ESBL production was evaluated by NCCLS guidelines and/or double-disk synergy test in K. pneumoniae blood isolates stored from January, 1998 to April, 2002. Sixty patients with bloodstream infection due to ESBL-producing K. pneumoniae (case patients) were compared with 159 matched control patients with bloodstream infection of non-ESBL-producing K. pneumoniae. Retrospective case-control study was performed. Results : There were no significant differences in age, sex, APACHE Ⅱ score, and the primary site of infection between the case and control groups. In multivariate analysis, significant independent risk factors associated with bloodstream infection due to ESBL-producing K. pneumoniae were urinary catheterization, invasive procedure within previous 72 hours, and the number of antibiotics administered within previous 30 days. In clinical response at 72 hours after initial antibiotic treatment, complete response rate was higher in the controls (13.3% vs. 40.3%, respectively, P<0.001), however, treatment failure rate was higher in the cases (33.3% vs. 11.9%, respectively, P<0.001). Overall 7-day mortality rates in the cases and the controls were was 20% (12/60) and 15.7% (25/159) (P=0.451), respectively, and overall 30-day mortality rates were 30% (18/60) and 24.5% (39/159), respectively (P=0.410). When the patients with bloodstream infection of ESBL-producing organism were evaluated and the patients who received inadequate definitive antibiotic treatment were excluded, delayed effective antibiotic treatment was found to be not associated with higher mortality. Conclusion : In patients infected with ESBL-producing K. pneumoniae bacteremia, clinical response rate at 72 hours after antimicrobial therapy was lower, but the increase of mortality rate was not significant. Delayed effective antibiotic treatment was not associated with higher mortality, when definitive appropriate antibiotic treatment was prescribed.

관학연계 주간보호센터 사업 운영 프로그램 개발 : 동작구민을 대상으로

한승의,김경희,정연강,전인희 중앙대학교 간호과학연구소 2001 중앙간호논문집 Vol.5 No.2

The purpose of this study was to sere as a basis for the development of more successful programs for the elderly who used adult day care center, by examining the Activities of Daily Living, Instrumental Activities of Daily Living and dementia symptom of elderly people who wed in Dongjak-gu in Seoul. Data for this present study were collected from 260 people via questionnares randomly distributed to over 65-year-old elderly people who lived in Dongjak-gu in Seoul from March to June, 2001. The findings of this study were as below: 1. For general characteristics, the women outnumbered the men, as the former group accounted for 63.8% of the subjects and 36.2% were male. By age, the largest age group was 71 to 75, which accounted for 43.2%. By disease, 87.3% suffered from disease, and most of them had mode than one disease. 2. For Activities of Daily Living, washing and dressing mean scored the highest with 2.96, and bathing stored the least with 2.87. 3. Concerning Instrumental Activities of Daily Living, what's in want of the greatest help was going shopping(4.5%), followed by cooking(4.5%) and laundering(4.5%) in the order named. 4. As a result of making a primary dementia screening test, 68 people(26.2%) were suspected to have dementia, and those people need to take dementia diagnosis test to fond out dementia prevalence.

法醫學者 崔棟

박의우,여인석 大韓法醫學會 1994 대한법의학회지 Vol.18 No.1

Forensic medicine in modern sense was introduced in early 20th century in our country. The first Korean forensic pathologist among medical school graduates was Dr. Choy Dong, who graduated from Severance Union Medical College(SUMC) in 1921. He was born in 1896 at Seoul, and entered SUMC in 1918. He went to Department of Forensic Medicine, Tohoku University Medical College, Sendai, Japan, and researched in the field of forensic medicine. He returned to Korea in 1936 and became a lecturer of forensic medicine. He had also lectured clinical pathology and parasitology. He resigned SUMC in 1948 because of some uncertain reasons.